Functionalization Of T Lymphocytes With Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles For Magnetically Controlled Immune Therapy

References

• World Health Organization International Agency for Research on Cancer. Fact sheets: world. 2018 Available from: http://gco.iarc.fr/today/data/factsheets/populations/900-world-fact-sheets.pdf Accessed 108, 2018.
   Google Scholar
• Galon J, Costes A, Sanchez-Cabo F, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science. 2006;313(5795):1960–1964. doi:10.1126/science.112913917008531
   PubMed Web of Science ®Google Scholar
• Jass JR. Lymphocytic infiltration and survival in rectal cancer. J Clin Pathol. 1986;39(6):585–589. doi:10.1136/jcp.39.6.5853722412
   PubMed Web of Science ®Google Scholar
• Hwang WT, Adams SF, Tahirovic E, Hagemann IS, Coukos G. Prognostic significance of tumor-infiltrating T cells in ovarian cancer: a meta-analysis. Gynecol Oncol. 2012;124(2):192–198. doi:10.1016/j.ygyno.2011.09.03922040834
   PubMed Web of Science ®Google Scholar
• Fridman WH, Pages F, Sautes-Fridman C, Galon J. The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer. 2012;12(4):298–306. doi:10.1038/nrc324522419253
   PubMed Web of Science ®Google Scholar
• Galon J, Angell Helen K, Bedognetti D, Marincola Francesco M. The continuum of cancer immunosurveillance: prognostic, predictive, and mechanistic signatures. Immunity. 2013;39(1):11–26. doi:10.1016/j.immuni.2013.07.00823890060
   PubMed Web of Science ®Google Scholar
• Gajewski TF, Schreiber H, Fu Y-X. Innate and adaptive immune cells in the tumor microenvironment. Nat Immunol. 2013;14(10):1014–1022. doi:10.1038/ni.270324048123
   PubMed Web of Science ®Google Scholar
• Lanitis E, Dangaj D, Irving M, Coukos G. Mechanisms regulating T-cell infiltration and activity in solid tumors. Ann Oncol. 2017;28(suppl_12):xii18–xii32. doi:10.1093/annonc/mdx07529045511
   PubMed Web of Science ®Google Scholar
• Kather JN, Suarez-Carmona M, Charoentong P, et al. Topography of cancer-associated immune cells in human solid tumors. eLife. 2018;7:e36967. doi:10.7554/eLife.4227030179157
   PubMedGoogle Scholar
• Carreau NA, Pavlick AC. Nivolumab and ipilimumab: immunotherapy for treatment of malignant melanoma. Future Oncol. 2019;15(4):349–358. doi:10.2217/fon-2018-060730334646
   PubMedGoogle Scholar
• Saruwatari K, Sato R, Nakane S, et al. The risks and benefits of immune checkpoint blockade in anti-AChR antibody-seropositive non-small cell lung cancer patients. Cancers. 2019;11(2):140. doi:10.3390/cancers11020140
   PubMed Web of Science ®Google Scholar
• van der Woude LL, Gorris MAJ, Halilovic A, Figdor CG, de Vries IJM. Migrating into the tumor: a roadmap for T cells. Trends Cancer. 2017;3(11):797–808. doi:10.1016/j.trecan.2017.09.00629120755
   PubMedGoogle Scholar
• Baeuerle PA, Reinhardt C. Bispecific T-cell engaging antibodies for cancer therapy. Cancer Res. 2009;69(12):4941. doi:10.1158/0008-5472.CAN-08-366019509221
   PubMed Web of Science ®Google Scholar
• Staton T. Amgen slaps record-breaking $178K price on rare leukemia drug Blincyto. 2014 Available from: https://www.fiercepharma.com/marketing/amgen-slaps-record-breaking-178k-price-on-rare-leukemia-drug-blincyto Accessed 131, 2019.
   Google Scholar
• Amann M, D’Argouges S, Lorenczewski G, et al. Antitumor activity of an EpCAM/CD3-bispecific BiTE antibody during long-term treatment of mice in the absence of T-cell anergy and sustained cytokine release. J Immunother. 2009;32(5):452–464. doi:10.1097/CJI.0b013e3181a1c09719609237
   PubMedGoogle Scholar
• Bean CP, Livingston JD. Superparamagnetism. J Appl Phys. 1959;30(4):S120–S129. doi:10.1063/1.2185850
   Google Scholar
• Wahajuddin AS. Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers. Int J Nanomedicine. 2012;7:3445–3471. doi:10.2147/IJN.S3032022848170
   PubMed Web of Science ®Google Scholar
• Tietze R, Lyer S, Durr S, et al. Efficient drug-delivery using magnetic nanoparticles–biodistribution and therapeutic effects in tumour bearing rabbits. Nanomedicine. 2013;9(7):961–971. doi:10.1016/j.nano.2013.05.00123669367
   PubMed Web of Science ®Google Scholar
• Vanecek V, Zablotskii V, Forostyak S, et al. Highly efficient magnetic targeting of mesenchymal stem cells in spinal cord injury. Int J Nanomedicine. 2012;7:3719–3730. doi:10.2147/IJN.S3282422888231
   PubMed Web of Science ®Google Scholar
• Chen J, Huang N, Ma B, et al. Guidance of stem cells to a target destination in vivo by magnetic nanoparticles in a magnetic field. ACS Appl Mater Interfaces. 2013;5(13):5976–5985. doi:10.1021/am400249n23749081
   PubMed Web of Science ®Google Scholar
• Cores J, Caranasos TG, Cheng K. Magnetically targeted stem cell delivery for regenerative medicine. J Funct Biomater. 2015;6(3):526–546. doi:10.3390/jfb603052626133387
   PubMedGoogle Scholar
• Goya GF, Marcos-Campos I, Fernandez-Pacheco R, et al. Dendritic cell uptake of iron-based magnetic nanoparticles. Cell Biol Int. 2008;32(8):1001–1005. doi:10.1016/j.cellbi.2008.04.00118534870
   PubMedGoogle Scholar
• Zhang Q, Wei W, Wang P, et al. Biomimetic magnetosomes as versatile artificial antigen-presenting cells to potentiate T-cell-based anticancer therapy. ACS Nano. 2017;11(11):10724–10732. doi:10.1021/acsnano.7b0495528921946
   PubMed Web of Science ®Google Scholar
• Mühlberger M, Janko C, Unterweger H, et al. Functionalization of T lymphocytes for magnetically controlled immune therapy: selection of suitable superparamagnetic iron oxide nanoparticles. J Magn Magn Mater. 2019;473:61–67. doi:10.1016/j.jmmm.2018.10.022
   Web of Science ®Google Scholar
• Elbialy NS, Fathy MM, Khalil WM. Doxorubicin loaded magnetic gold nanoparticles for in vivo targeted drug delivery. Int J Pharm. 2015;490(1–2):190–199. doi:10.1016/j.ijpharm.2015.05.03225997662
   PubMedGoogle Scholar
• Lugert S, Unterweger H, Muhlberger M, et al. Cellular effects of paclitaxel-loaded iron oxide nanoparticles on breast cancer using different 2D and 3D cell culture models. Int J Nanomedicine. 2019;14:161–180. doi:10.2147/IJN.S18788630613144
   PubMed Web of Science ®Google Scholar
• Munoz LE, Maueroder C, Chaurio R, Berens C, Herrmann M, Janko C. Colourful death: six-parameter classification of cell death by flow cytometry–dead cells tell tales. Autoimmunity. 2013;46(5):336–341. doi:10.3109/08916934.2012.75596023231469
   PubMed Web of Science ®Google Scholar
• Friedrich RP, Janko C, Poettler M, et al. Flow cytometry for intracellular SPION quantification: specificity and sensitivity in comparison with spectroscopic methods. Int J Nanomedicine. 2015;10:4185–4201. doi:10.2147/IJN.S8271426170658
   PubMed Web of Science ®Google Scholar
• Hanani M. Lucifer yellow - an angel rather than the devil. J Cell Mol Med. 2012;16(1):22–31. doi:10.1111/j.1582-4934.2011.01378.x21740513
   PubMed Web of Science ®Google Scholar
• Swanson JA, Yirinec BD, Silverstein SC. Phorbol esters and horseradish peroxidase stimulate pinocytosis and redirect the flow of pinocytosed fluid in macrophages. J Cell Biol. 1985;100(3):851–859. doi:10.1083/jcb.100.3.8513972898
   PubMedGoogle Scholar
• Mühlberger M, Janko C, Unterweger H, et al. Non-magnetic chromatographic separation of colloidally metastable superparamagnetic iron oxide nanoparticles and suspension cells. J Chromatogr B. 2019;1122–1123:83–89. doi:10.1016/j.jchromb.2019.05.033
   PubMed Web of Science ®Google Scholar
• Poller JM, Zaloga J, Schreiber E, et al. Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake. Int J Nanomedicine. 2017;12:3207–3220. doi:10.2147/IJN.S13236928458541
   PubMed Web of Science ®Google Scholar
• Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65(1–2):55–63. doi:10.1016/0022-1759(83)90303-46606682
   PubMed Web of Science ®Google Scholar
• Bahring F, Schlenk F, Wotschadlo J, et al. Suitability of Viability Assays for Testing Biological Effects of Coated Superparamagnetic Nanoparticles. IEEE Transactions on Magnetics 2013;49(1):383–388.
   Google Scholar
• Mühleisen L, Alev M, Unterweger H, et al. Analysis of hypericin-mediated effects and implications for targeted photodynamic therapy. Int J Mol Sci. 2017;18(7):1388. doi:10.3390/ijms18071388
   PubMed Web of Science ®Google Scholar
• Wang H, Joseph JA. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic Biol Med. 1999;27(5–6):612–616. doi:10.1016/S0891-5849(99)00107-010490282
   PubMed Web of Science ®Google Scholar
• Foucaud L, Wilson MR, Brown DM, Stone V. Measurement of reactive species production by nanoparticles prepared in biologically relevant media. Toxicol Lett. 2007;174(1–3):1–9. doi:10.1016/j.toxlet.2007.08.00117888595
   PubMed Web of Science ®Google Scholar
• Marsh M, McMahon HT. The structural era of endocytosis. Science. 1999;285(5425):215. doi:10.1126/science.285.5425.21510398591
   PubMed Web of Science ®Google Scholar
• Beer AJ, Holzapfel K, Neudorfer J, et al. Visualization of antigen-specific human cytotoxic T lymphocytes labeled with superparamagnetic iron-oxide particles. Eur Radiol. 2008;18(6):1087–1095. doi:10.1007/s00330-008-0874-418286290
   PubMedGoogle Scholar
• Liu L, Ye Q, Wu Y, et al. Tracking T-cells in vivo with a new nano-sized MRI contrast agent. Nanomedicine. 2012;8(8):1345–1354. doi:10.1016/j.nano.2012.02.01722406186
   PubMedGoogle Scholar
• Garden OA, Reynolds PR, Yates J, et al. A rapid method for labelling CD4+ T cells with ultrasmall paramagnetic iron oxide nanoparticles for magnetic resonance imaging that preserves proliferative, regulatory and migratory behaviour in vitro. J Immunol Methods. 2006;314(1–2):123–133. doi:10.1016/j.jim.2006.06.01016860821
   PubMedGoogle Scholar
• Zhao X, Su H, Yin G, Liu X, Liu Z, Suo X. High transfection efficiency of porcine peripheral blood T cells via nucleofection. Vet Immunol Immunopathol. 2011;144(3–4):179–186. doi:10.1016/j.vetimm.2011.10.00322055481
   PubMedGoogle Scholar
• Ebert O, Finke S, Salahi A, et al. Lymphocyte apoptosis: induction by gene transfer techniques. Gene Ther. 1997;4:296. doi:10.1038/sj.gt.33003949176514
   PubMed Web of Science ®Google Scholar
• Chicaybam L, Sodre AL, Curzio BA, Bonamino MH. An efficient low cost method for gene transfer to T lymphocytes. PLoS One. 2013;8(3):e60298–e60298. doi:10.1371/journal.pone.006029823555950
   PubMedGoogle Scholar
• Vairy S, Garcia JL, Teira P, Bittencourt H. CTL019 (tisagenlecleucel): CAR-T therapy for relapsed and refractory B-cell acute lymphoblastic leukemia. Drug Des Devel Ther. 2018;12:3885–3898. doi:10.2147/DDDT.S138765
   PubMed Web of Science ®Google Scholar
• Yu S, Li A, Liu Q, et al. Chimeric antigen receptor T cells: a novel therapy for solid tumors. J Hematol Oncol. 2017;10(1):78. doi:10.1186/s13045-017-0444-928356156
   PubMed Web of Science ®Google Scholar