Synergistic Anti-Staphylococcal Activity Of Niosomal Recombinant Lysostaphin-LL-37

References

• López-Igual R, Bernal-Bayard J, Rodríguez-Patón A, Ghigo J-M, Mazel D. Engineered toxin–intein antimicrobials can selectively target and kill antibiotic-resistant bacteria in mixed populations. Nat Biotechnol. 2019;1:755–760.
   Google Scholar
• Bumann D. Has nature already identified all useful antibacterial targets? Curr Opin Microbiol. 2008;11:387–392. doi:10.1016/j.mib.2008.08.00218804175
   PubMed Web of Science ®Google Scholar
• Niemirowicz K, Piktel E, Wilczewska AZ, et al. Core–shell magnetic nanoparticles display synergistic antibacterial effects against Pseudomonas aeruginosa and Staphylococcus aureus when combined with cathelicidin LL-37 or selected ceragenins. Int J Nanomed. 2016;11:5443. doi:10.2147/IJN.S113706
   PubMed Web of Science ®Google Scholar
• Browder HP, Zygmunt WA, Young J, Tavormina P. Lysostaphin: enzymatic mode of action. Biochem Biophys Res Commun. 1965;19:383–389. doi:10.1016/0006-291X(65)90473-014317407
   PubMed Web of Science ®Google Scholar
• Desbois AP, Gemmell CG, Coote PJ. In vivo efficacy of the antimicrobial peptide ranalexin in combination with the endopeptidase lysostaphin against wound and systemic meticillin-resistant Staphylococcus aureus (MRSA) infections. Int J Antimicrob Agents. 2010;35:559–565. doi:10.1016/j.ijantimicag.2010.01.01620206480
   PubMed Web of Science ®Google Scholar
• Polak J, Della Latta P, Blackburn P. In vitro activity of recombinant lysostaphin-antibiotic combinations toward methicillin-resistant Staphylococcus aureus. Diagn Micr Infec Dis. 1993;17:265–270. doi:10.1016/0732-8893(93)90034-5
   PubMed Web of Science ®Google Scholar
• Fumakia M, Ho EA. Nanoparticles encapsulated with LL37 and serpin A1 promotes wound healing and synergistically enhances antibacterial activity. Mol Pharm. 2016;13:2318–2331. doi:10.1021/acs.molpharmaceut.6b0009927182713
   PubMedGoogle Scholar
• Duplantier AJ, van Hoek ML. The human cathelicidin antimicrobial peptide LL-37 as a potential treatment for polymicrobial infected wounds. Front Immunol. 2013;4:143. doi:10.3389/fimmu.2013.0014323840194
   PubMed Web of Science ®Google Scholar
• Oren Z, Lerman JC, Gudmundsson GH, Agerberth B, Shai Y. Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity. Biochem J. 1999;341:501. doi:10.1042/bj341050110417311
   PubMed Web of Science ®Google Scholar
• Geitani R, Moubareck CA, Touqui L, Sarkis DK. Cationic antimicrobial peptides: alternatives and/or adjuvants to antibiotics active against methicillin-resistant Staphylococcus aureus and multidrug-resistant Pseudomonas aeruginosa. BMC Microbiol. 2019;19:54. doi:10.1186/s12866-019-1416-830849936
   PubMedGoogle Scholar
• Alaiwa MHA, Reznikov LR, Gansemer ND, et al. pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37. PNAS. 2014;111:18703–18708. doi:10.1073/pnas.142209111225512526
   PubMed Web of Science ®Google Scholar
• Laridi R, Kheadr E, Benech R-O, Vuillemard J, Lacroix C, Fliss I. Liposome encapsulated nisin Z: optimization, stability and release during milk fermentation. Int Dairy J. 2003;13:325–336. doi:10.1016/S0958-6946(02)00194-2
   Web of Science ®Google Scholar
• Colas J-C, Shi W, Rao VM, Omri A, Mozafari MR, Singh H. Microscopical investigations of nisin-loaded nanoliposomes prepared by Mozafari method and their bacterial targeting. Micron. 2007;38:841–847.17689087
   PubMed Web of Science ®Google Scholar
• Sanderson NM, Jones MN. Targeting of cationic liposomes to skin‐associated bacteria. Pest Sci. 1996;46:255–261. doi:10.1002/(SICI)1096-9063(199603)46:3<255::AID-PS345>3.0.CO;2-Y
   Google Scholar
• Jones MN. Use of liposomes to deliver bactericides to bacterial biofilms. Methods Enzymol. 2005;391:211–228.15721384
   PubMed Web of Science ®Google Scholar
• Cortesi R, Esposito E, Corradini F, et al. Non-phospholipid vesicles as carriers for peptides and proteins: production, characterization and stability studies. Int J Pharm. 2007;339:52–60. doi:10.1016/j.ijpharm.2007.02.02417395411
   PubMed Web of Science ®Google Scholar
• Kopermsub P, Mayen V, Warin C. Nanoencapsulation of nisin and ethylenediaminetetraacetic acid in niosomes and their antibacterial activity. AJSR. 2012;4:457.
   Google Scholar
• Rochdy Haj-Ahmad R, Ali Elkordy A, Shu Chaw C. In vitro characterisation of Span™ 65 niosomal formulations containing proteins. Curr Drug Deliv. 2015;12:628–639. doi:10.2174/156720181266615051109543225963305
   PubMed Web of Science ®Google Scholar
• Moghassemi S, Hadjizadeh A, Omidfar K. Formulation and characterization of bovine serum albumin-loaded niosome. AAPS PharmSciTech. 2017;18:27–33. doi:10.1208/s12249-016-0487-126817764
   PubMed Web of Science ®Google Scholar
• Manosroi A, Khanrin P, Werner RG, Götz F, Manosroi W, Manosroi J. Entrapment enhancement of peptide drugs in niosomes. J Microencapsul. 2010;27:272–280. doi:10.3109/0265204090313129320113169
   PubMed Web of Science ®Google Scholar
• Manosroi A, Lohcharoenkal W, Götz F, Werner RG, Manosroi W, Manosroi J. Cellular uptake enhancement of Tat-GFP fusion protein loaded in elastic niosomes. J Biomed Nanotechnol. 2011;7:366–376. doi:10.1166/jbn.2011.130021830477
   PubMed Web of Science ®Google Scholar
• Farhangnia L, Ghaznavi-Rad E, Mollaee N, Abtahi H. Cloning, expression, and purification of recombinant Lysostaphin from Staphylococcus simulans. Jundishapur J Microbiol. 2014;7:e10009.25147708
   PubMed Web of Science ®Google Scholar
• Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248–254. doi:10.1016/0003-2697(76)90527-3942051
   PubMed Web of Science ®Google Scholar
• Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. PNAS. 1979;76:4350–4354. doi:10.1073/pnas.76.9.4350388439
   PubMed Web of Science ®Google Scholar
• van Vuuren SF, Nkwanyana MN, de Wet H. Antimicrobial evaluation of plants used for the treatment of diarrhoea in a rural community in northern Maputaland, KwaZulu-Natal, South Africa. BMC Complem Altern M. 2015;15:53. doi:10.1186/s12906-015-0570-2
   PubMed Web of Science ®Google Scholar
• Tavano L, Muzzalupo R, Picci N, de Cindio B. Co-encapsulation of antioxidants into niosomal carriers: gastrointestinal release studies for nutraceutical applications. Colloids Surf B Biointerfaces. 2014;114:82–88. doi:10.1016/j.colsurfb.2013.09.05824176886
   PubMed Web of Science ®Google Scholar
• Lutz JB, Zehrer CL, Solfest SE, Walters S-A. A new in vivo test method to compare wound dressing fluid handling characteristics and wear time. Ostomy Wound Manag. 2011;57:28.
   PubMedGoogle Scholar
• Hua S. Comparison of in vitro dialysis release methods of loperamide-encapsulated liposomal gel for topical drug delivery. Int J Nanomedicine. 2014;9:735. doi:10.2147/IJN24511230
   PubMed Web of Science ®Google Scholar
• LiPuma JJ, Rathinavelu S, Foster BK, et al. In vitro activities of a novel nanoemulsion against Burkholderia and other multidrug-resistant cystic fibrosis-associated bacterial species. Antimicrob Agents Chemother. 2009;53:249–255. doi:10.1128/AAC.00691-0818955531
   PubMed Web of Science ®Google Scholar
• Zhao X, Drlica K. Restricting the selection of antibiotic-resistant mutants: a general strategy derived from fluoroquinolone studies. Clin Infect Dis. 2001;33:S147–S156. doi:10.1086/cid.2001.33.issue-s311524712
   PubMed Web of Science ®Google Scholar
• Desbois AP, Coote PJ. Bactericidal synergy of lysostaphin in combination with antimicrobial peptides. Eur J Clin Microbiol Inf Dis. 2011;30:1015–1021. doi:10.1007/s10096-011-1188-z
   PubMed Web of Science ®Google Scholar
• Kang J, Dietz MJ, Li B. Antimicrobial peptide LL-37 is bactericidal against Staphylococcus aureus biofilms. PLoS One. 2019;14:e0216676. doi:10.1371/journal.pone.021667631170191
   PubMed Web of Science ®Google Scholar
• Liu T, Guo R. Investigation of PEG 6000/Tween 80/Span 80/H 2 O niosome microstructure. Colloid Polym Sci. 2007;285:711–713. doi:10.1007/s00396-006-1627-z
   Web of Science ®Google Scholar
• Junyaprasert VB, Singhsa P, Suksiriworapong J, Chantasart D. Physicochemical properties and skin permeation of Span 60/Tween 60 niosomes of ellagic acid. Int J Pharm. 2012;423:303–311. doi:10.1016/j.ijpharm.2011.11.03222155414
   PubMed Web of Science ®Google Scholar
• Varshosaz J, Pardakhty A, Hajhashemi V-I, Najafabadi AR. Development and physical characterization of sorbitan monoester niosomes for insulin oral delivery. Drug Deliv. 2003;10:251–262. doi:10.1080/drd_10_4_25114612341
   PubMed Web of Science ®Google Scholar
• Moazeni E, Gilani K, Sotoudegan F, et al. Formulation and in vitro evaluation of ciprofloxacin containing niosomes for pulmonary delivery. J Microencapsul. 2010;27:618–627. doi:10.3109/02652048.2010.50657920681747
   PubMed Web of Science ®Google Scholar
• Khaksa G, D’Souza R, Lewis S, Udupa N. Pharmacokinetic study of niosome encapsulated insulin. Indian J Exp Biol. 2000;38(9):901–905.12561948
   PubMedGoogle Scholar
• Gurrapu A, Jukanti R, Bobbala SR, Kanuganti S, Jeevana JB. Improved oral delivery of valsartan from maltodextrin based proniosome powders. Adv Powder Technol. 2012;23:583–590. doi:10.1016/j.apt.2011.06.005
   Web of Science ®Google Scholar
• Agarwal R, Katare O, Vyas S. Preparation and in vitro evaluation of liposomal/niosomal delivery systems for antipsoriatic drug dithranol. Int J Pharm. 2001;228:43–52. doi:10.1016/S0378-5173(01)00810-911576767
   PubMed Web of Science ®Google Scholar
• Pardakhty A, Moazeni E, Varshosaz J, Hajhashemi V, Najafabadi AR. Pharmacokinetic study of niosome-loaded insulin in diabetic rats. DARU. 2011;19:404.23008685
   PubMed Web of Science ®Google Scholar
• Hwang SH, Maitani Y, Takayama K, NAGAI T. High entrapment of insulin and bovine serum albumin into neutral and positively-charged liposomes by the remote loading method. Chem Pharm Bull (Tokyo). 2000;48:325–329. doi:10.1248/cpb.48.32510726850
   PubMed Web of Science ®Google Scholar
• Xie J, Ng WJ, Lee LY, Wang CH. Encapsulation of protein drugs in biodegradable microparticles by co-axial electrospray. J Colloid Interface Sci. 2008;317:469–476. doi:10.1016/j.jcis.2007.09.08217945246
   PubMed Web of Science ®Google Scholar
• Müller RH, MaÈder K, Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery–a review of the state of the art. Eur J Pharm Biopharm. 2000;50:161–177. doi:10.1016/S0939-6411(00)00087-410840199
   PubMed Web of Science ®Google Scholar
• Ebrahimi HA, Javadzadeh Y, Hamidi M, Jalali MB. Repaglinide-loaded solid lipid nanoparticles: effect of using different surfactants/stabilizers on physicochemical properties of nanoparticles. DARU. 2015;23:46. doi:10.1186/s40199-015-0128-326392174
   PubMed Web of Science ®Google Scholar
• Dash S, Murthy PN, Nath L, Chowdhury P. Kinetic modeling on drug release from controlled drug delivery systems. Acta Pol Pharm. 2010;67:217–223.20524422
   PubMed Web of Science ®Google Scholar
• Yang X-Y, Li C-R, Lou R-H, et al. In vitro activity of recombinant lysostaphin against Staphylococcus aureus isolates from hospitals in Beijing, China. J Med Microbiol. 2007;56:71–76. doi:10.1099/jmm.0.46788-017172520
   PubMedGoogle Scholar
• Boge L. Lipid-Based Liquid Crystals as Drug Delivery Vehicles for Antimicrobial Peptides. Department of Chemistry and Chemical Engineering, Chalmers University of Technology; 2018.
   Google Scholar
• Lewies A, Wentzel JF, Jordaan A, Bezuidenhout C, Du Plessis LH. Interactions of the antimicrobial peptide nisin Z with conventional antibiotics and the use of nanostructured lipid carriers to enhance antimicrobial activity. Int J Pharm. 2017;526:244–253. doi:10.1016/j.ijpharm.2017.04.07128461263
   PubMedGoogle Scholar
• Abbaszadegan A, Ghahramani Y, Gholami A, et al. The effect of charge at the surface of silver nanoparticles on antimicrobial activity against gram-positive and gram-negative bacteria: a preliminary study. J Nanomater. 2015;16:53.
   Google Scholar
• Were LM, Bruce BD, Davidson PM, Weiss J. Size, stability, and entrapment efficiency of phospholipid nanocapsules containing polypeptide antimicrobials. J Agric Food Chem. 2003;51:8073–8079. doi:10.1021/jf034836814690399
   PubMed Web of Science ®Google Scholar
• Kopermsub P, Mayen V, Warin C. Potential use of niosomes for encapsulation of nisin and EDTA and their antibacterial activity enhancement. Food Res Int. 2011;44:605–612. doi:10.1016/j.foodres.2010.12.011
   Web of Science ®Google Scholar
• Were LM, Bruce B, Davidson PM, Weiss J. Encapsulation of nisin and lysozyme in liposomes enhances efficacy against Listeria monocytogenes. J Food Prot. 2004;67:922–927. doi:10.4315/0362-028X-67.5.92215151228
   PubMed Web of Science ®Google Scholar
• Amusa AS, Satish J, Gopalakrishna P. In vitro activities of fluoroquinolones entrapped in non-ionic surfactant vesicles against ciprofloxacin-resistant bacteria strains. IJPSDR. 2012;1:5.
   Google Scholar
• Newman SP. Principles of metered-dose inhaler design. Respir Care. 2005;50:1177–1190.16122401
   PubMedGoogle Scholar
• Niven R. Feasibility studies with recombinant human granulocyte colony-stimulating factor. Lung Biol Health Dis. 1997;107:413–452.
   Google Scholar