Spray-Dried Silica Xerogel Nanoparticles as a Promising Gastroretentive Carrier System for the Management of Chemotherapy-Induced Nausea and Vomiting

References

• Buckstein R, Kerbel R, Cheung M, et al. Lenalidomide and metronomic melphalan for CMML and higher risk MDS: a phase 2 clinical study with biomarkers of angiogenesis. Leuk Res. 2014;38(7):756–763. doi:10.1016/j.leukres.2014.03.02224819395
   PubMed Web of Science ®Google Scholar
• Chaiyasat P, Chaiyasat A, Boontung W, Promdsorn S, Thipsit S. Preparation and characterization of poly(divinylbenzene) microcapsules containing octadecane. Mater Sci Appl. 2011;02(08):1007–1013.
   Google Scholar
• Fu YJ, Mi FL, Wong TB, Shyu SS. Characteristic and controlled release of anticancer drug loaded poly (D,L-lactide) microparticles prepared by spray drying technique. J Microencapsul. 2001;18(6):733–747. doi:10.1080/0265204001005564911695638
   PubMed Web of Science ®Google Scholar
• Tadros MI, Al-Mahallawi AM. Long-circulating lipoprotein-mimic nanoparticles for smart intravenous delivery of a practically-insoluble antineoplastic drug: development, preliminary safety evaluations and preclinical pharmacokinetic studies. Int J Pharm. 2015;493(1–2):439–450. doi:10.1016/j.ijpharm.2015.08.01126253380
   PubMed Web of Science ®Google Scholar
• Thirumaran R, Prendergast GC, Gilman PB. Cytotoxic chemotherapy in clinical treatment of cancer. Cancer Immunother. 2007;101–116.
   Google Scholar
• Roscoe JA, Morrow GR, Hickok JT, Stern RM. Nausea and vomiting remain a significant clinical problem: trends over time in controlling chemotherapy-induced nausea and vomiting in 1413 patients treated in community clinical practices. J Pain Symptom Manage. 2000;20(2):113–121. doi:10.1016/S0885-3924(00)00159-710989249
   PubMedGoogle Scholar
• Ballatori E, Roila F. Impact of nausea and vomiting on quality of life in cancer patients during chemotherapy. Health Qual Life Outcomes. 2003;1:46. doi:10.1186/1477-7525-1-4614521717
   PubMedGoogle Scholar
• Farrell C, Brearley SG, Pilling M, Molassiotis A. The impact of chemotherapy-related nausea on patients’ nutritional status, psychological distress and quality of life. Support Care Cancer. 2013;21(1):59–66. doi:10.1007/s00520-012-1493-922610269
   PubMedGoogle Scholar
• Roila F, Warr D, Aapro M, et al. Delayed emesis: moderately emetogenic chemotherapy (Single-day chemotherapy regimens only). Support Care Cancer. 2011;Suppl 1:S57–S62. doi:10.1007/s00520-010-1039-y
   Google Scholar
• Kalia V, Garg T, Rath G, Goyal AK. Development and evaluation of a sublingual film of the antiemetic granisetron hydrochloride. Artif Cells Nanomedicine Biotechnol. 2016;44(3):842–846.
   PubMed Web of Science ®Google Scholar
• Brayfield A, ed. Martindale: The Complete Drug Reference. 38th ed. London: The Pharmaceutical Press; 2014.
   Google Scholar
• Stankus T. Drugs and poisons. Serials Librarian. 1996;27:87–102. doi:10.1300/J123v27n02_07
   Web of Science ®Google Scholar
• Kim JJ, Tannock IF. Repopulation of cancer cells during therapy: an important cause of treatment failure. Nat Rev Cancer. 2005;5(7):516–525. doi:10.1038/nrc165015965493
   PubMed Web of Science ®Google Scholar
• Kerbel RS, Klement G, Pritchard KI, Kamen B. Continuous low-dose anti-angiogenic/metronomic chemotherapy: from the research laboratory into the oncology clinic. Ann Oncol. 2002;13(1):12–15. doi:10.1093/annonc/mdf09311863092
   PubMedGoogle Scholar
• Browder T, Butterfield CE, Kräling BM, et al. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res. 2000;60(7):1878–1886.10766175
   PubMed Web of Science ®Google Scholar
• Croissant JG, Cattoën X, et al. Syntheses and applications of periodic mesoporous organosilica nanoparticles. Nanoscale. 2015;7(48):20318–20334. doi:10.1039/C5NR05649G26585498
   PubMed Web of Science ®Google Scholar
• Croissant JG, Fatieiev Y, Almalik A, Khashab NM. Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications. Adv Healthc Mater. 2018;7(4):1700831.
   Web of Science ®Google Scholar
• Huang WF, Tsui GCP, Tang CY, Yang M. Optimization strategy for encapsulation efficiency and size of drug loaded silica xerogel/polymer core-shell composite nanoparticles prepared by gelation-emulsion method. Polym Eng Sci. 2018;58(5):742–751. doi:10.1002/pen.24609
   Web of Science ®Google Scholar
• Zhai W, He C, Wu L, et al. Degradation of hollow mesoporous silica nanoparticles in human umbilical vein endothelial cells. J Biomed Mater Res - Part B Appl Biomater. 2012;100 B(5):1397–1403. doi:10.1002/jbm.b.3271122566482
   PubMedGoogle Scholar
• Ekkapongpisit M, Giovia A, Follo C, Caputo G, Isidoro C. Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: effects of size and surface charge groups. Int J Nanomedicine. 2012;7:4147–4158. doi:10.2147/IJN.S3380322904626
   PubMed Web of Science ®Google Scholar
• Chatterji DC, Yeager RL, Gallelli JF. Kinetics of chlorambucil hydrolysis using high-pressure liquid chromatography J Pharm Sci 1982;71(1):50–54. doi:10.1002/jps.2600710113
   Google Scholar
• Antovska P, Cvetkovska M, Goračinova K. Preparation and characterization of sol-gel processed spray dried silica xerogel microparticles as carriers of heparin sodium. Bull Chem Technol Macedonia. 2006;25(2):121–126.
   Google Scholar
• Levy MY, Benita S. Drug release from submicronized o/w emulsion: a new in vitro kinetic evaluation model. Int J Pharm. 1990;66(1–3):29–37. doi:10.1016/0378-5173(90)90381-D
   Web of Science ®Google Scholar
• Zhuang CY, Li N, Wang M, et al. Preparation and characterization of vinpocetine loaded nanostructured lipid carriers (NLC) for improved oral bioavailability. Int J Pharm. 2010;394(1–2):179–185. doi:10.1016/j.ijpharm.2010.05.00520471464
   PubMed Web of Science ®Google Scholar
• Bhardwaj U, Burgess DJ. A novel USP apparatus 4 based release testing method for dispersed systems. Int J Pharm. 2010;388(1–2):287–294. doi:10.1016/j.ijpharm.2010.01.00920083176
   PubMedGoogle Scholar
• Tadros MI, Fahmy RH. Controlled-release triple anti-inflammatory therapy based on novel gastroretentive sponges: characterization and magnetic resonance imaging in healthy volunteers. Int J Pharm. 2014;472(1–2):27–39. doi:10.1016/j.ijpharm.2014.06.01324928130
   PubMedGoogle Scholar
• Washburn EW. Note on a method of determining the distribution of pore sizes in a porous material. Proc Natl Acad Sci USA. 1921;7(4):115–116. doi:10.1073/pnas.7.4.11516576588
   PubMedGoogle Scholar
• Orlu M, Cevher E, Araman A. Design and evaluation of colon specific drug delivery system containing flurbiprofen microsponges. Int J Pharm. 2006;318(1–2):103–117. doi:10.1016/j.ijpharm.2006.03.02516687222
   PubMedGoogle Scholar
• Song H, Nie S, Yang X, et al. Characterization and in vivo evaluation of novel lipid-chlorambucil nanospheres prepared using a mixture of emulsifiers for parenteral administration. Int J Nanomedicine. 2010;5(1):933–942. doi:10.2147/IJN.S1459621187945
   PubMedGoogle Scholar
• Danks AE, Hall SR, Schnepp Z. The evolution of “sol-gel” chemistry as a technique for materials synthesis. Mater Horizons. 2016;3(2):91–112. doi:10.1039/C5MH00260E
   Web of Science ®Google Scholar
• Elsagh A. Synthesis of silica nanostructures and optimization of their size and morphology by use of changing in synthesis conditions. E-Journal Chem. 2012;9(2):659–668. doi:10.1155/2012/109765
   Google Scholar
• Kortesuo P, Ahola M, Kangas M, Yli-Urpo A, Kiesvaara J, Marvola M. In vitro release of dexmedetomidine from silica xerogel monoliths: effect of sol-gel synthesis parameters. Int J Pharm. 2001;221(1–2):107–114. doi:10.1016/S0378-5173(01)00656-111397572
   PubMedGoogle Scholar
• Kortesuo P, Ahola M, Kangas M, et al. Effect of synthesis parameters of the sol–gel-processed spray-dried silica gel microparticles on the release rate of dexmedetomidine. Biomaterials. 2002;23(13):2795–2801. doi:10.1016/S0142-9612(02)00016-912059031
   PubMed Web of Science ®Google Scholar
• Kesmez Ö, Burunkaya E, Kiraz N, Çamurlu HE, Asiltürk M, Arpaç E. Effect of acid, water and alcohol ratios on sol-gel preparation of antireflective amorphous SiO2 coatings. J Non Cryst Solids. 2011;357(16–17):3130–3135. doi:10.1016/j.jnoncrysol.2011.05.003
   Web of Science ®Google Scholar
• Maeda H, Matsumura Y. Tumoritropic and lymphotropic principles of macromolecular drugs. Crit Rev Ther Drug Carrier Syst. 1989;6(3):193–210.2692843
   PubMed Web of Science ®Google Scholar
• Yuan F, Dellian M, Fukumura D, et al. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res. 1995;55(17):3752–3756.7641188
   PubMed Web of Science ®Google Scholar
• Seleem MN, Munusamy P, Ranjan A, Alqublan H, Pickrell G, Sriranganathan N. Silica-antibiotic hybrid nanoparticles for targeting intracellular pathogens. Antimicrob Agents Chemother. 2009;53(10):4270–4274. doi:10.1128/AAC.00815-0919667284
   PubMed Web of Science ®Google Scholar
• International Agency for Research on Cancer. IARC monographs on the evaluation of carcinogenic risks to humans. IARC Monogr Eval Carcinog Risks to Humans. 2010;93:9–38.
   Google Scholar
• Wang X, Cao Y, Yan H. Chlorambucil loaded in mesoporous polymeric microspheres as oral sustained release formulations with enhanced hydrolytic stability. Mater Sci Eng C. 2018;91:564–569. doi:10.1016/j.msec.2018.05.078
   PubMed Web of Science ®Google Scholar
• Van Speybroeck M, Barillaro V, Do TT, et al. Ordered mesoporous silica material SBA-15: a broad-spectrum formulation platform for poorly soluble drugs. J Pharm Sci. 2009;98(8):2648–2658. doi:10.1002/jps.2163819072861
   PubMed Web of Science ®Google Scholar
• Abd-Elbary A, Tadros MI, Alaa-Eldin AA. Sucrose stearate-enriched lipid matrix tablets of etodolac: modulation of drug release, diffusional modeling and structure elucidation studies. AAPS PharmSciTech. 2013;14(2):656–668. doi:10.1208/s12249-013-9951-323572253
   PubMed Web of Science ®Google Scholar
• Nel AE, Mädler L, Velegol D, et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater. 2009;8(7):543–557. doi:10.1038/nmat244219525947
   PubMed Web of Science ®Google Scholar
• Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer. 2004;4(11):891–899. doi:10.1038/nrc147815516961
   PubMed Web of Science ®Google Scholar