References
- MillerDMPolanskyDAThomasSDMithramycin selectively inhibits transcription of G-C containing DNAAm J Med Sci198729453883942962490
- SastryMFialaRPatelDJSolution structure of mithramycin dimers bound to partially overlapping sites on DNAJ Mol Biol199525156746897666419
- SastryMPatelDJSolution structure of the mithramycin dimer-DNA complexBiochemistry19933226658866048329387
- BlumeSWSnyderRCRayRThomasSKollerCAMillerDMMithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivoJ Clin Invest1991885161316211834700
- SnyderRCRayRBlumeSMillerDMMithramycin blocks transcriptional initiation of the c-myc P1 and P2 promotersBiochemistry19913017429042971827033
- SafeSAbdelrahimMSp transcription factor family and its role in cancerEur J Cancer200541162438244816209919
- AbdelrahimMSmithR3rdBurghardtRSafeSRole of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cellsCancer Res200464186740674915374992
- BlackARBlackJDAzizkhan-CliffordJSp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancerJ Cell Physiol2001188214316011424081
- KennedyBJMetabolic and toxic effects of mithramycin during tumor therapyAm J Med19704944945034320120
- BrownJHKennedyBJMithramycin in the treatment of disseminated testicular neoplasmsN Engl J Med196527211111814224214
- KollerCAMillerDMPreliminary observations on the therapy of the myeloid blast phase of chronic granulocytic leukemia with plicamycin and hydroxyureaN Engl J Med198631523143314382431313
- RyanWGMithramycin for Paget’s disease of boneN Engl J Med19702832111715474359
- RyanWGSchwartzTBNorthropGExperiences in the treatment of Paget’s disease of bone with mithramycinJAMA19702137115311575468261
- RemsingLLGarcia-BernardoJGonzalezAKetopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathwayJ Am Chem Soc200212481606161411853433
- AlbertiniVJainAVignatiSNovel GC-rich DNA-binding compound produced by a genetically engineered mutant of the mithramycin producer Streptomyces argillaceus exhibits improved transcriptional repressor activity: implications for cancer therapyNucleic Acids Res20063461721173416571899
- RemsingLLGonzálezAMNur-e-AlamMMithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesisJ Am Chem Soc2003125195745575312733914
- TakakuraYFujitaTHashidaMSezakiHDisposition characteristics of macromolecules in tumor-bearing micePharm Res1990743393461694582
- van VlerkenLVyasTAmijiMPoly(ethylene glycol)-modified Nanocarriers for tumor-targeted and intracellular deliveryPharm Res20072481405141417393074
- SmartTLomasHMassignaniMFlores-MerinoMVPerezLRBattagliaGBlock copolymer nanostructuresNano Today200833–43846
- BaeYKataokaKIntelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymersAdv Drug Deliv Rev2009611076878419422866
- ChenHKimSLiLWangSParkKChengJXRelease of hydrophobic molecules from polymer micelles into cell membranes revealed by Forster resonance energy transfer imagingProc Natl Acad Sci U S A2008105186596660118445654
- LeeHJBaeYCross-linked nanoassemblies from poly(ethylene glycol)-poly(aspartate) block copolymers as stable supramolecular templates for particulate drug deliveryBiomacromolecules20111272686269621644544
- BeckerMLRemsenEEPanDWooleyKLPeptide-derivatized shell-cross- linked nanoparticles. 1. Synthesis and characterizationBioconjug Chem200415469970915264856
- WestKROttoSReversible covalent chemistry in drug deliveryCurr Drug Discov Technol20052312316016472224
- JonesATGumbletonMDuncanRUnderstanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systemsAdv Drug Deliv Rev200355111353135714597135
- Vander HeidenMGCantleyLCThompsonCBUnderstanding the Warburg effect: the metabolic requirements of cell proliferationScience200932459301029103319460998
- GilliesRJRobeyIGatenbyRACauses and consequences of increased glucose metabolism of cancersJ Nucl Med200849Suppl 24S42S
- BaeYNishiyamaNKataokaKIn vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartmentsBioconjug Chem20071841131113917488066
- HowardMDPontaAEckmanAJayMBaeYPolymer micelles with hydrazone-ester dual linkers for tunable release of dexamethasonePharm Res201128102435244621614636
- PontaABaeYPEG-poly(amino acid) block copolymer micelles for tunable drug releasePharm Res201027112330234220372992
- AlaniAWBaeYRaoDAKwonGSPolymeric micelles for the pH-dependent controlled, continuous low dose release of paclitaxelBiomaterials20103171765177219959225
- JinH-JKanthasamyAAnantharamVRanaAKanthasamyAGTranscriptional regulation of pro-apoptotic protein kinase Cδ: implications for oxidative stress-induced neuronal cell deathJ Biol Chem2011286198401985921467032
- SeznecJSilkenstedtBNaumannUTherapeutic effects of the Sp1 inhibitor mithramycin A in glioblastomaJ Neurooncol201110136537720556479
- SleimanSFLangleyBCBassoMMithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegenerationJ Neurosci2011316858687021543616
- GaoYJiaZKongXCombining betulinic acid and mithramycin A effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesisCancer Res2011715182519321673052
- TagashiraMKitagawaTIsonishiSOkamotoAOchiaiKOhtakeYMithramycin represses MDR1 gene expression in vitro, modulating multidrug resistanceBiol Pharm Bull200023892692910963297
- TagashiraMKitagawaTNozatoNTwo novel C-glycosides of aureolic acid repress transcription of the MDR1 geneChem Pharm Bull (Tokyo)200048457557810783084
- GroharPJWoldemichaelGMGriffinLBIdentification of an Inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screeningJ Natl Cancer Inst201110396297821653923
- GibsonMNur-e-alamMLipataFOliveiraMARohrJCharacterization of kinetics and products of the Baeyer-Villiger oxygenase MtmOIV, the key enzyme of the biosynthetic pathway toward the natural product anticancer drug mithramycin from Streptomyces argillaceusJ Am Chem Soc200512750175941759516351075
- FrezardFGarnier-SuillerotADemicheliCEncapsulation of mithramycin in liposomes in response to a transmembrane gradient of calcium ionsJ Incl Phenom Macrocycl Chem19972815162