74
Views
5
CrossRef citations to date
0
Altmetric
Original Research

Oridonin nanosuspension was more effective than free oridonin on G2/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line

, , , , , , & show all
Pages 1793-1804 | Published online: 03 Apr 2012

References

  • AbelsonPHMedicine from plantsScience19902475132300807
  • FujiKNodeMSaiMFujitaETakedaSUnemiNTerpenoids. LIII. Antitumor activity of trichorabdals and related compoundsChem Pharm Bull (Tokyo)198937147214762776235
  • HanQBLiMLLiSHMouSHLinZWSunHDEnt-kaurane diterpenoids from Isodon rubescens var. lushanensisChem Pharm Bull (Tokyo)20035179079312843583
  • IkezoeTChenSSTongXJHeberDTaguchiHKoefflerHPOridonin induces growth inhibition and apoptosis of a variety of human cancer cellsInt J Oncol2003231187119312964003
  • LiCYWangEQChengYBaoJKOridonin: an active diterpenoid targeting cell cycle arrest, apoptotic and autophagic pathways for cancer therapeuticsInt J Biochem Cell Biol20114370170421295154
  • ChenSGaoJHalickaHDHuangXTraganosFDarzynkiewiczZThe cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineageInt J Oncol20052657958815703811
  • JinHYTanXZLiuXFDingYJDownregulation of AP-1 gene expression is an initial event in the oridonin-mediated inhibition of colorectal cancer: studies in vitro and in vivoJ Gastroenterol Hepatol20112670671521418301
  • MüllerMWFriessHKöningerJFactors influencing survival after bypass procedures in patients with advanced pancreatic adenocarcinomasAm J Surg200819522122818154768
  • WrayCJAhmadSAMatthewsJBLowyAMSurgery for pancreatic cancer: recent controversies and current practiceGastroenterology20051281626164115887155
  • RabinowBENanosuspensions in drug deliveryNat Rev Drug Discov2004378579615340388
  • PatravaleVBDateAAKulkarniRMNanosuspensions: a promising drug delivery strategyJ Pharm Pharmacol20045682784015233860
  • KesisoglouFPanmaiSWuYHNanosizing-oral formulation development and biopharmaceutical evaluationAdv Drug Deliv Rev20075963164417601629
  • GaoLZhangDChenMZhengTWangSPreparation and characterization of an oridonin nanosuspension for solubility and dissolution velocity enhancementDrug Dev Ind Pharm2007331332133918097807
  • LouHYZhangXMGaoLIn vitro and in vivo antitumor activity of oridonin nanosuspensionInt J Pharm200937918118619563872
  • GaoLZhangDRChenMHStudies on pharmacokinetics and tissue distribution of oridonin nanosuspensionInt J Pharm200835532132718242896
  • StormGBelliotSODaemenTLasicDDSurface medication of nanoparticles to oppose uptake by the mononuclear phagocyte systemAdv Drug Deliv Rev1995173148
  • KirkinVJoosSZörnigMThe role of Bcl-2 family members in tumorigenesisBiochim Biophys Acta2004164422924914996506
  • YinCKnudsonCMKorsmeyerSJVan DykeTBax suppresses tumorigenesis and stimulates apoptosis in vivoNature19973856376409024662
  • NicholsonDWAliAThornberryNAIdentification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosisNature199537637437596430
  • DenaultJBSalvesenGSCaspases: keys in the ignition of cell deathChem Rev20021024489450012475198
  • PhilchenkovAACaspases as regulators of apoptosis and other cell functionsBiochemistry (Mosc)20036836537612765517
  • ZouHLiYLiuXWangXAn APAF-1·Cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9J Biol Chem1999274115491155610206961
  • SleeEAHarteMTKluckRMOrdering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent mannerJ Cell Biol19991442812929922454
  • LiversidgeGGCundyKCParticle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogsInt J Pharm19951259197
  • LiversidgeGGConzentinoPDrug particle size reduction for decreasing gastric irritancy and enhancing absorption of naproxen in ratsInt J Pharm1995125309313
  • BloomJCrossFRMultiple levels of cyclin specificity in cell-cycle controlNat Rev Mol Cell Biol2007814916017245415
  • HanYHKimSZKimSHParkWHArsenic trioxide inhibits the growth of Calu-6 cells via inducing a G2 arrest of the cell cycle and apoptosis accompanied with the depletion of GSHCancer Lett2008270405518539383
  • ChengYQiuFYeYCTashiroSOnoderaSIkejimaTOridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cellsArch Biochem Biophys2009490707519699177