Inhaled chemotherapy in lung cancer: future concept of nanomedicine

References

• JemalABrayFCenterMMFerlayJWardEFormanDGlobal cancer statisticsCA Cancer J Clin2011612699021296855
   PubMed Web of Science ®Google Scholar
• LangerCJHarrisJHorwitzEMPhase II study of low-dose paclitaxel and cisplatin in combination with split-course concomitant twice-daily reirradiation in recurrent squamous cell carcinoma of the head and neck: results of Radiation Therapy Oncology Group Protocol 9911J Clin Oncol200725304800480517947728
   PubMed Web of Science ®Google Scholar
• CurranWJJrSchillerJHWolkinACComisRLAddressing the current challenges of non-small-cell lung cancer clinical trial accrualClin Lung Cancer20089422222618650170
   PubMed Web of Science ®Google Scholar
• SomerRAShermanELangerCJRestrictive eligibility limits access to newer therapies in non-small-cell lung cancer: the implications of Eastern Cooperative Oncology Group 4599Clin Lung Cancer20089210210518501096
   PubMed Web of Science ®Google Scholar
• NovelloSLongoMLevraMGToward therapies tailored to patient characteristicsJ Thorac Oncol20072Suppl 5S384117457231
   PubMed Web of Science ®Google Scholar
• SubramanianJWaqarSNGovindanRTargeted therapy in lung cancer: lessons learned from past experiencesJ Thorac Oncol2011611 Suppl 4S1786178822005530
   PubMed Web of Science ®Google Scholar
• Garcia SarDAguadoLMontes BayonMRelationships between cisplatin-induced adducts and DNA strand-breaks, mutation and recombination in vivo in somatic cells of Drosophila melanogaster, under different conditions of nucleotide excision repairMutat Res20127411–2818822108251
   PubMed Web of Science ®Google Scholar
• HosomiYShibuyaMNihoSPhase II study of topotecan with cisplatin in Japanese patients with small cell lung cancerAnticancer Res201131103449345621965760
   PubMed Web of Science ®Google Scholar
• ShepherdFACrowleyJVan HouttePThe International Association for the Study of Lung Cancer lung cancer staging project: proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancerJ Thorac Oncol20072121067107718090577
   PubMed Web of Science ®Google Scholar
• HunterTBManimalaNJLuddyKACatlinTAntoniaSJPaclitaxel and TRAIL synergize to kill paclitaxel-resistant small cell lung cancer cells through a caspase-independent mechanism mediated through AIFAnticancer Res201131103193320421965726
   PubMed Web of Science ®Google Scholar
• SchillerJHHarringtonDBelaniCPComparison of four chemotherapy regimens for advanced non-small-cell lung cancerN Engl J Med20023462929811784875
   PubMed Web of Science ®Google Scholar
• MinchintonAITannockIFDrug penetration in solid tumoursNat Rev Cancer20066858359216862189
   PubMed Web of Science ®Google Scholar
• KemenyNENiedzwieckiDHollisDRHepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481)J Clin Oncol20062491395140316505413
   PubMed Web of Science ®Google Scholar
• ArmstrongDKBundyBWenzelLIntraperitoneal cisplatin and paclitaxel in ovarian cancerN Engl J Med20063541344316394300
   PubMed Web of Science ®Google Scholar
• GuerinCOliviAWeingartJDLawsonHCBremHRecent advances in brain tumor therapy: local intracerebral drug delivery by polymersInvest New Drugs2004221273714707492
   PubMed Web of Science ®Google Scholar
• RobinsonWRCoberlyCBeyerJLewisABallardCOffice-based intraperitoneal chemotherapy for ovarian cancerJ Oncol Pract20084522522820856699
   PubMedGoogle Scholar
• HofstraLSBosAMde VriesEGA phase I and pharmacokinetic study of intraperitoneal topotecanBr J Cancer200185111627163311742479
   PubMed Web of Science ®Google Scholar
• OsakiTHanagiriTNakanishiRYoshinoITagaSYasumotoKBronchial arterial infusion is an effective therapeutic modality for centrally located early-stage lung cancer: results of a pilot studyChest199911551424142810334163
   PubMed Web of Science ®Google Scholar
• MaischBRisticADPankuweitSNeubauerAMollRNeoplastic pericardial effusion. Efficacy and safety of intrapericardial treatment with cisplatinEur Heart J200223201625163112323163
   PubMed Web of Science ®Google Scholar
• MarkmanMClearySPfeifleCHowellSBCisplatin administered by the intracavitary route as treatment for malignant mesotheliomaCancer198658118213708543
   PubMed Web of Science ®Google Scholar
• RuschVWFiglinRGodwinDPiantadosiSIntrapleural cisplatin and cytarabine in the management of malignant pleural effusions: a Lung Cancer Study Group trialJ Clin Oncol1991923133191988578
   PubMed Web of Science ®Google Scholar
• GoldbergEPHadbaARAlmondBAMarottaJSIntratumoral cancer chemotherapy and immunotherapy: opportunities for nonsystemic preoperative drug deliveryJ Pharm Pharmacol200254215918011848280
   PubMed Web of Science ®Google Scholar
• DuvillardCRomanetPCosmidisABeaudouinNChauffertBPhase 2 study of intratumoral cisplatin and epinephrine treatment for locally recurrent head and neck tumorsAnn Otol Rhinol Laryngol20041133 Pt 122923315053208
   PubMed Web of Science ®Google Scholar
• LabirisNRDolovichMBPulmonary drug delivery. Part I: physiological factors affecting therapeutic effectiveness of aerosolized medicationsBr J Clin Pharmacol200356658859914616418
   PubMed Web of Science ®Google Scholar
• LaubeBLThe expanding role of aerosols in systemic drug delivery, gene therapy, and vaccinationRespir Care20055091161117616122400
   PubMedGoogle Scholar
• BakkerEMVolpiSSaloniniEImproved treatment response to dornase alfa in cystic fibrosis patients using controlled inhalationEur Respir J20113861328133521737560
   PubMed Web of Science ®Google Scholar
• BiltonDRobinsonPCooperPInhaled dry powder mannitol in cystic fibrosis: an efficacy and safety studyEur Respir J20113851071108021478216
   PubMed Web of Science ®Google Scholar
• YuKNMinai-TehraniAChangSHAerosol delivery of small hairpin osteopontin blocks pulmonary metastasis of breast cancer in micePLoS One2010512e1562321203518
   PubMed Web of Science ®Google Scholar
• ZarogoulidisPPapanasNKouliatsisGSpyratosDZarogoulidisKMaltezosEInhaled insulin: too soon to be forgotten?J Aerosol Med Pulm Drug Deliv201124521322321689020
   PubMed Web of Science ®Google Scholar
• ZarogoulidisPEleftheriadouESapardanisIFeasibility and effectiveness of inhaled carboplatin in NSCLC patientsInvest New Drugs July 82011 Epub ahead of print
   Web of Science ®Google Scholar
• TatsumuraTYamamotoKMurakamiATsudaMSugiyamaSNew chemotherapeutic method for the treatment of tracheal and bronchial cancers – nebulization chemotherapyGan No Rinsho1983297765770 Japanese6308308
   PubMedGoogle Scholar
• TatsumuraTKoyamaSTsujimotoMKitagawaMKagamimoriSFurther study of nebulisation chemotherapy, a new chemotherapeutic method in the treatment of lung carcinomas: fundamental and clinicalBr J Cancer1993686114611498260366
   PubMed Web of Science ®Google Scholar
• GautamAKoshkinaNPaclitaxel (Taxol) and taxoid derivates for lung cancer treatment: potential for aerosol deliveryCurr Cancer Drug Targets20033428729612871059
   PubMed Web of Science ®Google Scholar
• HersheyAEKurzmanIDForrestLJInhalation chemotherapy for macroscopic primary or metastatic lung tumors: proof of principle using dogs with spontaneously occurring tumors as a modelClin Cancer Res1999592653265910499645
   PubMed Web of Science ®Google Scholar
• KoshkinaNVGolunskiERobertsLEGilbertBEKnightVCyclosporin A aerosol improves the anticancer effect of paclitaxel aerosol in miceJ Aerosol Med200417171415120008
   PubMedGoogle Scholar
• MinchinRFJohnstonMRAikenMABoydMRPharmacokinetics of doxorubicin in isolated lung of dogs and humans perfused in vivoJ Pharmacol Exp Ther198422911931986707934
   PubMed Web of Science ®Google Scholar
• OttersonGAVillalona-CaleroMAHicksWPhase I/II study of inhaled doxorubicin combined with platinum-based therapy for advanced non-small cell lung cancerClin Cancer Res20101682466247320371682
   PubMed Web of Science ®Google Scholar
• GaviniEManuntaLGiuaSAchenzaGGiunchediPSpray-dried poly(D,L-lactide) microspheres containing carboplatin for veterinary use: in vitro and in vivo studiesAAPS Pharm Sci Tech200561E108114
   Web of Science ®Google Scholar
• KhannaCVailDMTargeting the lung: preclinical and comparative evaluation of anticancer aerosols in dogs with naturally occurring cancersCurr Cancer Drug Targets20033426527312871057
   PubMed Web of Science ®Google Scholar
• GagnadouxFHureauxJVecellioLAerosolized chemotherapyJ Aerosol Med Pulm Drug Deliv2008211617018518832
   PubMed Web of Science ®Google Scholar
• SeltingKWaldrepJCReineroCFeasibility and safety of targeted cisplatin delivery to a select lung lobe in dogs via the AeroProbe intracorporeal nebulization catheterJ Aerosol Med Pulm Drug Deliv200821325526818759657
   PubMed Web of Science ®Google Scholar
• WittgenBPKunstPWPerkinsWRLeeJKPostmusPEAssessing a system to capture stray aerosol during inhalation of nebulized liposomal cisplatinJ Aerosol Med200619338539117034313
   PubMedGoogle Scholar
• GagnadouxFPapeALLemarieEAerosol delivery of chemotherapy in an orthotopic model of lung cancerEur Respir J200526465766116204597
   PubMed Web of Science ®Google Scholar
• ChaoPDeshmukhMKutscherHLPulmonary targeting microparticulate camptothecin delivery system: anticancer evaluation in a rat orthotopic lung cancer modelAnticancer Drugs2010211657619966540
   PubMed Web of Science ®Google Scholar
• TsengCLSuWYYenKCYangKCLinFHThe use of biotinylated-EGF-modified gelatin nanoparticle carrier to enhance cisplatin accumulation in cancerous lungs via inhalationBiomaterials200930203476348519345990
   PubMed Web of Science ®Google Scholar
• SchafferMWRoySSMukherjeeSOngDEDasSKUptake of all-trans retinoic acid-containing aerosol by inhalation to lungs in a guinea pig model system – a pilot studyExp Lung Res2010361059360121043991
   PubMed Web of Science ®Google Scholar
• RoaWHAzarmiSAl-HallakMHFinlayWHMaglioccoAMLobenbergRInhalable nanoparticles, a non-invasive approach to treat lung cancer in a mouse modelJ Control Release20111501495521059378
   PubMed Web of Science ®Google Scholar
• HureauxJLagarceFGagnadouxFLipid nanocapsules: readyt-o- use nanovectors for the aerosol delivery of paclitaxelEur J Pharm Biopharm200973223924619560538
   PubMed Web of Science ®Google Scholar
• AndersonKLawsonKASimmons-MenchacaMSunLSandersBGKlineKAlpha-TEA plus cisplatin reduces human cisplatin-resistant ovarian cancer cell tumor burden and metastasisExp Biol Med (Maywood)2004229111169117615564444
   PubMed Web of Science ®Google Scholar
• KoshkinaNVWaldrepJCRobertsLEGolunskiEMeltonSKnightVPaclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma modelClin Cancer Res20017103258326211595722
   PubMed Web of Science ®Google Scholar
• GarbuzenkoOBSaadMPozharovVPReuhlKRMainelisGMinkoTInhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistanceProc Natl Acad Sci U S A201010723107371074220498076
   PubMed Web of Science ®Google Scholar
• OttersonGAVillalona-CaleroMASharmaSPhase I study of inhaled doxorubicin for patients with metastatic tumors to the lungsClin Cancer Res20071341246125217317836
   PubMed Web of Science ®Google Scholar
• WittgenBPKunstPWvan der BornKPhase I study of aerosolized SLIT cisplatin in the treatment of patients with carcinoma of the lungClin Cancer Res20071382414242117438100
   PubMed Web of Science ®Google Scholar
• WattenbergLWWiedmannTSEstensenRDChemoprevention of cancer of the upper respiratory tract of the Syrian golden hamster by aerosol administration of difluoromethylornithine and 5-fluorouracilCancer Res20046472347234915059884
   PubMed Web of Science ®Google Scholar
• KnightVKoshkinaNVGolunskiERobertsLEGilbertBECyclosporin A aerosol improves the anticancer effect of paclitaxel aerosol in miceTrans Am Clin Climatol Assoc200411539540417060982
   PubMedGoogle Scholar
• VerschraegenCFGilbertBELoyerEClinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)-camptothecin in patients with advanced pulmonary malignanciesClin Cancer Res20041072319232615073107
   PubMed Web of Science ®Google Scholar
• LawsonKAAndersonKSnyderRMNovel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasisCancer Chemother Pharmacol200454542143115197487
   PubMed Web of Science ®Google Scholar
• El-GendyNBerklandCCombination chemotherapeutic dry powder aerosols via controlled nanoparticle agglomerationPharm Res20092671752176319415471
   PubMed Web of Science ®Google Scholar
• AzarmiSTaoXChenHFormulation and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particlesInt J Pharm20063191–215516116713150
   PubMed Web of Science ®Google Scholar
• HitzmanCJWattenbergLWWiedmannTSPharmacokinetics of 5-fluorouracil in the hamster following inhalation delivery of lipid-coated nanoparticlesJ Pharm Sci20069561196121116639722
   PubMed Web of Science ®Google Scholar
• RodriguezCOJrCrabbsTAWilsonDWAerosol gemcitabine: preclinical safety and in vivo antitumor activity in osteosarcoma-bearing dogsJ Aerosol Med Pulm Drug Deliv201023419720619803732
   PubMed Web of Science ®Google Scholar
• KoshkinaNVKleinermanESAerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastasesInt J Cancer2005116345846315800950
   PubMed Web of Science ®Google Scholar
• KoshkinaNVGilbertBEWaldrepJCSeryshevAKnightVDistribution of camptothecin after delivery as a liposome aerosol or following intramuscular injection in miceCancer Chemother Pharmacol199944318719210453719
   PubMed Web of Science ®Google Scholar
• SharmaSWhiteDImondiARPlackeMEVailDMKrisMGDevelopment of inhalational agents for oncologic useJ Clin Oncol20011961839184711251016
   PubMed Web of Science ®Google Scholar
• SwiftDLAerosols and humidity therapy. Generation and respiratory deposition of therapeutic aerosolsAm Rev Respir Dis19801225 Pt 271777458052
   PubMed Web of Science ®Google Scholar
• PhippsPRGondaIAndersonSDBaileyDBautovichGRegional deposition of saline aerosols of different tonicities in normal and asthmatic subjectsEur Respir J199478147414827957833
   PubMed Web of Science ®Google Scholar
• ShinoharaHDistribution of lymphatic stomata on the pleural surface of the thoracic cavity and the surface topography of the pleural mesothelium in the golden hamsterAnat Rec1997249116239294645
   PubMedGoogle Scholar
• Lai-FookSJMechanical factors in lung liquid distributionAnnu Rev Physiol1993551551798466171
   PubMed Web of Science ®Google Scholar
• NunnJFNunn’s Applied Respiratory Physiology4th edOxford, UKButterworth-Heineman1993
   Google Scholar
• DeffebachMECharanNBLakshminarayanSButlerJThe bronchial circulation. Small, but a vital attribute of the lungAm Rev Respir Dis198713524634813544986
   PubMed Web of Science ®Google Scholar
• HoutmeyersEGosselinkRGayan-RamirezGDecramerMRegulation of mucociliary clearance in health and diseaseEur Respir J19991351177118810414423
   PubMed Web of Science ®Google Scholar
• SummersQAInhaled drugs and the lungClin Exp Allergy19912132592681863889
   PubMed Web of Science ®Google Scholar
• StoneKCMercerRRGehrPStockstillBCrapoJDAllometric relationships of cell numbers and size in the mammalian lungAm J Respir Cell Mol Biol1992622352431540387
   PubMed Web of Science ®Google Scholar
• FolkessonHGMatthayMAWestromBRKimKJKarlssonBWHastingsRHAlveolar epithelial clearance of proteinJ Appl Physiol1996805143114458727524
   PubMed Web of Science ®Google Scholar
• MartonenTBMathematical model for the selective deposition of inhaled pharmaceuticalsJ Pharm Sci19938212119111998308694
   PubMed Web of Science ®Google Scholar
• SuarezSHickeyAJDrug properties affecting aerosol behaviorRespir Care200045665266610894458
   PubMedGoogle Scholar
• IlowiteJSGorvoyJDSmaldoneGCQuantitative deposition of aerosolized gentamicin in cystic fibrosisAm Rev Respir Dis19871366144514493688646
   PubMed Web of Science ®Google Scholar
• MessinaMSSmaldoneGCEvaluation of quantitative aerosol techniques for use in bronchoprovocation studiesJ Allergy Clin Immunol19857522522573968336
   PubMed Web of Science ®Google Scholar
• DolovichMBKillianDWolffRKObminskiGNewhouseMTPulmonary aerosol deposition in chronic bronchitis: intermittent positive pressure breathing versus quiet breathingAm Rev Respir Dis19771153397402320924
   PubMed Web of Science ®Google Scholar
• DolovichMBSanchisJRossmanCNewhouseMTAerosol penetrance: a sensitive index of peripheral airways obstructionJ Appl Physiol1976403468471931865
   PubMed Web of Science ®Google Scholar
• DavisJNStaggDInterrelationships of the volume and time components of individual breaths in resting manJ Physiol197524524814981142186
   PubMed Web of Science ®Google Scholar
• KoshkinaNVKnightVGilbertBEGolunskiERobertsLWaldrepJCImproved respiratory delivery of the anticancer drugs, camptothecin and paclitaxel, with 5% CO2-enriched air: pharmacokinetic studiesCancer Chemother Pharmacol200147545145611391862
   PubMed Web of Science ®Google Scholar
• StegenKNeujensACrombezGHermansDVan de WoestijneKPVan den BerghONegative affect, respiratory reactivity, and somatic complaints in a CO2 enriched air inhalation paradigmBiol Psychol1998491–21091229792488
   PubMed Web of Science ®Google Scholar
• KleinstreuerCZhangZLiZModeling airflow and particle transport/deposition in pulmonary airwaysRespir Physiol Neurobiol20081631–312813818674643
   PubMed Web of Science ®Google Scholar
• ZhangZKleinstreuerCKimCSAirflow and nanoparticle deposition in a 16-generation tracheobronchial airway modelAnn Biomed Eng200836122095211018850271
   PubMed Web of Science ®Google Scholar
• CrankJThe Mathematics of Diffusion2nd edOxford, UKClarendon Press1975
   Google Scholar
• LeuAJBerkDALymboussakiAAlitaloKJainRKAbsence of functional lymphatics within a murine sarcoma: a molecular and functional evaluationCancer Res200060164324432710969769
   PubMed Web of Science ®Google Scholar
• JainRKMunnLLFukumuraDDissecting tumour pathophysiology using intravital microscopyNat Rev Cancer20022426627612001988
   PubMed Web of Science ®Google Scholar
• JainRKDelivery of molecular and cellular medicine to solid tumorsAdv Drug Deliv Rev1997262–3719010837535
   PubMed Web of Science ®Google Scholar
• MilosevicMFFylesAWWongRInterstitial fluid pressure in cervical carcinoma: within tumor heterogeneity, and relation to oxygen tensionCancer19988212241824269635535
   PubMed Web of Science ®Google Scholar
• HeldinCHRubinKPietrasKOstmanAHigh interstitial fluid pressure – an obstacle in cancer therapyNat Rev Cancer200441080681315510161
   PubMed Web of Science ®Google Scholar
• JainRKBarriers to drug delivery in solid tumorsSci Am1994271158658066425
   PubMed Web of Science ®Google Scholar
• JainRKTransport of molecules in the tumor interstitium: a reviewCancer Res19874712303930513555767
   PubMed Web of Science ®Google Scholar
• WeberAMorlinGCohenMWilliams-WarrenJRamseyBSmithAEffect of nebulizer type and antibiotic concentration on device performancePediatr Pulmonol19972342492609141110
   PubMed Web of Science ®Google Scholar
• EschenbacherWLBousheyHASheppardDAlteration in osmolarity of inhaled aerosols cause bronchoconstriction and cough, but absence of a permeant anion causes cough aloneAm Rev Respir Dis198412922112156696320
   PubMed Web of Science ®Google Scholar
• JonasDEWinesRCMDelMonteMDrug Class Review: Controller Medications for Asthma: Final Update 1 ReportPortland, OROregon Health & Science University2011
   Google Scholar
• DolovichMBRamsdaleEHReplacing CFC aerosols with powdersCMAJ19901421010362337836
   PubMed Web of Science ®Google Scholar
• NewmanSPTherapeutic inhalation agents and devices. Effectiveness in asthma and bronchitisPostgrad Med19847651942036435107
   PubMed Web of Science ®Google Scholar
• BennettWDSmaldoneGCHuman variation in the peripheral air-space deposition of inhaled particlesJ Appl Physiol1987624160316103597231
   PubMed Web of Science ®Google Scholar
• DolovichMRyanGNewhouseMTAerosol penetration into the lung; influence on airway responsesChest198180Suppl 68348367307620
   PubMed Web of Science ®Google Scholar
• CromptonGKProblems patients have using pressurized aerosol inhalersEur J Respir Dis Suppl19821191011046954081
   PubMedGoogle Scholar
• NewmanSPPaviaDMorenFSheahanNFClarkeSWDeposition of pressurised aerosols in the human respiratory tractThorax198136152557292382
   PubMed Web of Science ®Google Scholar
• NewmanSPPaviaDGarlandNClarkeSWEffects of various inhalation modes on the deposition of radioactive pressurized aerosolsEur J Respir Dis Suppl198211957656807705
   PubMedGoogle Scholar
• PaviaDThomsonMLClarkeSWShannonHSEffect of lung function and mode of inhalation on penetration of aerosol into the human lungThorax1977322194197867333
   PubMed Web of Science ®Google Scholar
• NewmanSPWeiszAWTalaeeNClarkeSWImprovement of drug delivery with a breath actuated pressurised aerosol for patients with poor inhaler techniqueThorax199146107127161750017
   PubMed Web of Science ®Google Scholar
• ChapmanKRLoveLBrubakerHA comparison of breath-actuated and conventional metered-dose inhaler inhalation techniques in elderly subjectsChest19931045133213378222783
   PubMed Web of Science ®Google Scholar
• DolovichMRationale for spacer use in childrenPediatr Pulmonol Suppl1997161841859443266
   PubMedGoogle Scholar
• PedersenSInhalers and nebulizers: which to choose and whyRespir Med199690269778730324
   PubMed Web of Science ®Google Scholar
• DolovichMNew propellant-free technologies under investigationJ Aerosol Med199912Suppl 1S91710623341
   PubMedGoogle Scholar
• NewmanSPMorenFTrofastETalaeeNClarkeSWDeposition and clinical efficacy of terbutaline sulphate from Turbuhaler, a new multi-dose powder inhalerEur Respir J1989232472522731602
   PubMed Web of Science ®Google Scholar
• LabirisNRDolovichMBPulmonary drug delivery. Part II: the role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medicationsBr J Clin Pharmacol200356660061214616419
   PubMed Web of Science ®Google Scholar
• BorgstromLBondessonEMorenFTrofastENewmanSPLung deposition of budesonide inhaled via Turbuhaler: a comparison with terbutaline sulphate in normal subjectsEur Respir J19947169738143834
   PubMed Web of Science ®Google Scholar
• ClarkARHollingworthAMThe relationship between powder inhaler resistance and peak inspiratory conditions in healthy volunteers – implications for in vitro testingJ Aerosol MedSummer19936299110
   PubMedGoogle Scholar
• ChrystynHIs inhalation rate important for a dry powder inhaler? Using the In-Check Dial to identify these ratesRespir Med200397218118712587970
   PubMed Web of Science ®Google Scholar
• LavoriniFMagnanADubusJCEffect of incorrect use of dry powder inhalers on management of patients with asthma and COPDRespir Med2008102459360418083019
   PubMed Web of Science ®Google Scholar
• AmaniAYorkPChrystynHClarkBJDoDQDetermination of factors controlling the particle size in nanoemulsions using artificial neural networksEur J Pharm Sci2008351–2425118617002
   PubMed Web of Science ®Google Scholar
• DolovichMBAhrensRCHessDRDevice selection and outcomes of aerosol therapy: Evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and ImmunologyChest2005127133537115654001
   PubMed Web of Science ®Google Scholar
• KendrickAHSmithECWilsonRSSelecting and using nebuliser equipmentThorax199752Suppl 2S921019155861
   PubMed Web of Science ®Google Scholar
• BoeJDennisJHO’DriscollBREuropean Respiratory Society Guidelines on the use of nebulizersEur Respir J200118122824211510796
   PubMed Web of Science ®Google Scholar
• SmithECDenyerJKendrickAHComparison of twenty three nebulizer/compressor combinations for domiciliary useEur Respir J199587121412217589407
   PubMed Web of Science ®Google Scholar
• BrandPBeckmannHMaas EnriquezMPeripheral deposition of alpha1-protease inhibitor using commercial inhalation devicesEur Respir J200322226326712952258
   PubMed Web of Science ®Google Scholar
• NivenRWIpAYMittelmanSPrestrelskiSJArakawaTSome factors associated with the ultrasonic nebulization of proteinsPharm Res199512153597724488
   PubMed Web of Science ®Google Scholar
• WagnerAVorauer-UhlKKatingerHNebulization of liposomal rh-Cu/Zn-SOD with a novel vibrating membrane nebulizerJ Liposome Res200616211312516753966
   PubMed Web of Science ®Google Scholar
• ElhissiAMKarnamKKDanesh-AzariMRGillHSTaylorKMFormulations generated from ethanol-based proliposomes for delivery via medical nebulizersJ Pharm Pharmacol200658788789416805947
   PubMed Web of Science ®Google Scholar
• KleemannESchmehlTGesslerTBakowskyUKisselTSeegerWIloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: formulation aspects and stabilityPharm Res200724227728717211729
   PubMed Web of Science ®Google Scholar
• JohnsonJCWaldrepJCGuoJDhandRAerosol delivery of recombinant human DNase I: in vitro comparison of a vibrating-mesh nebulizer with a jet nebulizerRespir Care200853121703170819025706
   PubMed Web of Science ®Google Scholar
• SmaldoneGCBergENikanderKVariation in pediatric aerosol delivery: importance of facemaskJ Aerosol Med200518335436316181009
   PubMedGoogle Scholar
• HarrisKWSmaldoneGCFacial and ocular deposition of nebulized budesonide: effects of face mask designChest2008133248248818071018
   PubMed Web of Science ®Google Scholar
• SmaldoneGCSangwanSShahAFacemask design, facial deposition, and delivered dose of nebulized aerosolsJ Aerosol Med.200720Suppl 1S667517411408
   PubMedGoogle Scholar
• ErzingerSSchueeppKGBrooks-WildhaberJDevadasonSGWildhaberJHFacemasks and aerosol delivery in vivoJ Aerosol Med200720Suppl 1S788317411409
   PubMedGoogle Scholar
• KleinstreuerCZhangZDonohueJFTargeted drug-aerosol delivery in the human respiratory systemAnnu Rev Biomed Eng20081019522018412536
   PubMed Web of Science ®Google Scholar
• DunneAO’HaraTDevaneJA new approach to modelling the relationship between in vitro and in vivo drug dissolution/absorptionStat Med199918141865187610407257
   PubMed Web of Science ®Google Scholar
• ZierenbergBOptimizing the in vitro performance of RespimatJ Aerosol Med199912Suppl 1S192410623337
   PubMedGoogle Scholar
• NewmanSPSteedKPReaderSJHooperGZierenbergBEfficient delivery to the lungs of flunisolide aerosol from a new portable hand-held multidose nebulizerJ Pharm Sci19968599609648877887
   PubMed Web of Science ®Google Scholar
• NewmanSPBrownJSteedKPReaderSJKladdersHLung deposition of fenoterol and flunisolide delivered using a novel device for inhaled medicines: comparison of RESPIMAT with conventional metered-dose inhalers with and without spacer devicesChest199811349579639554631
   PubMed Web of Science ®Google Scholar
• BatemanEDTashkinDSiafakasNA one-year trial of tiotropium Respimat plus usual therapy in COPD patientsRespir Med2010104101460147220620037
   PubMed Web of Science ®Google Scholar
• StormGCrommelinDJColloidal systems for tumor targetingHybridoma19971611191259085138
   PubMedGoogle Scholar
• SuarezSGonzalez-RothiRJSchreierHHochhausGEffect of dose and release rate on pulmonary targeting of liposomal triamcinolone acetonide phosphatePharm Res19981534614659563078
   PubMed Web of Science ®Google Scholar
• FieldingRMAbraRMFactors affecting the release rate of terbutaline from liposome formulations after intratracheal instillation in the guinea pigPharm Res1992922202231553346
   PubMed Web of Science ®Google Scholar
• CryanSACarrier-based strategies for targeting protein and peptide drugs to the lungsAAPS J200571E204116146340
   PubMed Web of Science ®Google Scholar
• Gonzalez-RothiRJSuarezSHochhausGPulmonary targeting of liposomal triamcinolone acetonide phosphatePharm Res19961311169917038956337
   PubMed Web of Science ®Google Scholar
• Gonzalez-RothiRJStraubLCacaceJLSchreierHLiposomes and pulmonary alveolar macrophages: functional and morphologic interactionsExp Lung Res19911746877051657589
   PubMed Web of Science ®Google Scholar
• LasicDDLiposomes in Gene DeliveryBoca Raton, FLCRC Press1997
   Google Scholar
• AllenTMLiposomal drug formulations. Rationale for development and what we can expect for the futureDrugs19985657477569829150
   PubMed Web of Science ®Google Scholar
• SchreierHGagneLBockTPhysicochemical properties and in vitro toxicity of cationic liposome cDNA complexesPharm Acta Helv19977242152239372644
   PubMedGoogle Scholar
• NivenRWSchreierHNebulization of liposomes. I. Effects of lipid compositionPharm Res1990711112711332293210
   PubMed Web of Science ®Google Scholar
• DesaiTRHancockREFinlayWHA facile method of delivery of liposomes by nebulizationJ Control Release2002841–2697812399169
   PubMed Web of Science ®Google Scholar
• NivenRWSpeerMSchreierHNebulization of liposomes. II. The effects of size and modeling of solute release profilesPharm Res1991822172212023870
   PubMed Web of Science ®Google Scholar
• NivenRWCarvajalTMSchreierHNebulization of liposomes. III. The effects of operating conditions and local environmentPharm Res1992945155201495897
   PubMed Web of Science ®Google Scholar
• JoshiMMisraADry powder inhalation of liposomal ketotifen fumarate: formulation and characterizationInt J Pharm20012231–2152711451628
   PubMed Web of Science ®Google Scholar
• Skalko-BasnetNPavelicZBecirevic-LacanMLiposomes containing drug and cyclodextrin prepared by the one-step spray-drying methodDrug Dev Ind Pharm200026121279128411147128
   PubMed Web of Science ®Google Scholar
• OmriABeaulacCBouhajibMMontplaisirSSharkawiMLagaceJPulmonary retention of free and liposome-encapsulated tobramycin after intratracheal administration in uninfected rats and rats infected with Pseudomonas aeruginosaAntimicrob Agents Chemother1994385109010958067743
   PubMed Web of Science ®Google Scholar
• WoodleMCCollinsLRSponslerEKossovskyNPapahadjopoulosDMartinFJSterically stabilized liposomes. Reduction in electrophoretic mobility but not electrostatic surface potentialBiophys J19926149029101581503
   PubMed Web of Science ®Google Scholar
• DeolPKhullerGKLung specific stealth liposomes: stability, biodistribution and toxicity of liposomal antitubercular drugs in miceBiochim Biophys Acta199713342–31611729101710
   PubMed Web of Science ®Google Scholar
• HutchinsonFGFurrBJBiodegradable polymers for controlled release of peptides and proteinsHoriz Biochem Biophys198991111292656473
   PubMedGoogle Scholar
• EhrhardtCFiegelJFuchsSDrug absorption by the respiratory mucosa: cell culture models and particulate drug carriersJ Aerosol Med200215213113912184863
   PubMedGoogle Scholar
• KawashimaYYamamotoHTakeuchiHFujiokaSHinoTPulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effectJ Control Release1999621–227928710518661
   PubMed Web of Science ®Google Scholar
• ChengYSYazzieDGaoJMuggliDEtterJRosenthalGJParticle characteristics and lung deposition patterns in a human airway replica of a dry powder formulation of polylactic acid produced using super-critical fluid technologyJ Aerosol Med2003161657312737686
   PubMedGoogle Scholar
• DhimanNKhullerGKProtective efficacy of mycobacterial 71-kDa cell wall associated protein using poly (DL-lactide-co-glycolide) microparticles as carrier vehiclesFEMS Immunol Med Microbiol199821119289657317
   PubMedGoogle Scholar
• EvoraCSorianoIRogersRAShakesheffKNHanesJLangerRRelating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: the effect of 1,2-dipalmitoylphosphatidylcholineJ Control Release1998512–31431529685911
   PubMed Web of Science ®Google Scholar
• FiegelJEhrhardtCSchaeferUFLehrCMHanesJLarge porous particle impingement on lung epithelial cell monolayers – toward improved particle characterization in the lungPharm Res200320578879612751635
   PubMed Web of Science ®Google Scholar
• BittnerBKisselTUltrasonic atomization for spray drying: a versatile technique for the preparation of protein loaded biodegradable microspheresJ Microencapsul199916332534110340218
   PubMed Web of Science ®Google Scholar
• TakeuchiHYamamotoHKawashimaYMucoadhesive nanoparticulate systems for peptide drug deliveryAdv Drug Deliv Rev2001471395411251244
   PubMed Web of Science ®Google Scholar
• LangerRDrug delivery and targetingNature1998392Suppl 66795109579855
   PubMed Web of Science ®Google Scholar
• TsapisNBennettDJacksonBWeitzDAEdwardsDATrojan particles: large porous carriers of nanoparticles for drug deliveryProc Natl Acad Sci U S A20029919120011200512200546
   PubMed Web of Science ®Google Scholar
• EdwardsDAHanesJCaponettiGLarge porous particles for pulmonary drug deliveryScience19972765320186818719188534
   PubMed Web of Science ®Google Scholar
• CannonGJSwansonJAThe macrophage capacity for phagocytosisJ Cell Sci1992101Pt 49079131527185
   PubMed Web of Science ®Google Scholar
• SteckelHBolzenNAlternative sugars as potential carriers for dry powder inhalationsInt J Pharm20042701–229730614726144
   PubMed Web of Science ®Google Scholar
• KobayashiSKondoSJuniKPulmonary delivery of salmon calcitonin dry powders containing absorption enhancers in ratsPharm Res199613180838668684
   PubMed Web of Science ®Google Scholar
• WintersMAKnutsonBLDebenedettiPGPrecipitation of proteins in supercritical carbon dioxideJ Pharm Sci19968565865948773954
   PubMed Web of Science ®Google Scholar
• SellersSPClarkGSSieversRECarpenterJFDry powders of stable protein formulations from aqueous solutions prepared using supercritical CO(2)-assisted aerosolizationJ Pharm Sci200190678579711357179
   PubMed Web of Science ®Google Scholar
• HickeyWAFactors influencing the distortion of sex ratio in Aedes aegyptiJ Med Entomol1970767277355503471
   PubMed Web of Science ®Google Scholar
• MaaYFNguyenPASweeneyTShireSJHsuCCProtein inhalation powders: spray drying vs spray freeze dryingPharm Res199916224925410100310
   PubMed Web of Science ®Google Scholar
• KlinkDTChaoSGlickMCScanlinTFNuclear translocation of lactosylated poly-L-lysine/cDNA complex in cystic fibrosis airway epithelial cellsMol Ther20013683184111407896
   PubMed Web of Science ®Google Scholar
• KawashimaYSeriganoTHinoTYamamotoHTakeuchiHA new powder design method to improve inhalation efficiency of pranlukast hydrate dry powder aerosols by surface modification with hydroxypropylmethylcellulose phthalate nanospheresPharm Res19981511174817529833998
   PubMed Web of Science ®Google Scholar
• RajewskiRAStellaVJPharmaceutical applications of cyclodextrins. 2. In vivo drug deliveryJ Pharm Sci19968511114211698923319
   PubMed Web of Science ®Google Scholar
• WoodleMCScariaPGaneshSSterically stabilized polyplex: ligand-mediated activityJ Control Release2001741–330931111489511
   PubMed Web of Science ®Google Scholar
• KlonneDRDoddDELoscoPETroupCMTylerTRTwo-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 ratsDrug Chem Toxicol198912139482714207
   PubMed Web of Science ®Google Scholar
• ZhangLZhuWSongLEffects of hydroxylpropyl-beta-cyclodextrin on in vitro insulin stabilityInt J Mol Sci20091052031204019564937
   PubMed Web of Science ®Google Scholar
• BruckAAbu-DahabRBorchardGSchaferUFLehrCMLectin- functionalized liposomes for pulmonary drug delivery: interaction with human alveolar epithelial cellsJ Drug Target20019424125111697028
   PubMed Web of Science ®Google Scholar
• Abu-DahabRSchaferUFLehrCMLectin-functionalized liposomes for pulmonary drug delivery: effect of nebulization on stability and bioadhesionEur J Pharm Sci2001141374611457648
   PubMed Web of Science ®Google Scholar
• YiSMHarsonREZabnerJWelshMJLectin binding and endocytosis at the apical surface of human airway epitheliaGene Ther20018241826183211821935
   PubMed Web of Science ®Google Scholar
• KlossAHenkleinPSieleDThe cell-penetrating peptide octa-arginine is a potent inhibitor of proteasome activitiesEur J Pharm Biopharm200972121922519027853
   PubMed Web of Science ®Google Scholar
• StrayerMSGuttentagSHBallardPLTargeting type II and Clara cells for adenovirus-mediated gene transfer using the surfactant protein B promoterAm J Respir Cell Mol Biol19981811119448040
   PubMed Web of Science ®Google Scholar
• GorenDHorowitzATTzemachDTarshishMZalipskySGabizonANuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pumpClin Cancer Res2000651949195710815920
   PubMed Web of Science ®Google Scholar
• CristianoRJRothJAEpidermal growth factor mediated DNA delivery into lung cancer cells via the epidermal growth factor receptorCancer Gene Ther1996314108785711
   PubMed Web of Science ®Google Scholar
• LundbergMWikstromSJohanssonMCell surface adherence and endocytosis of protein transduction domainsMol Ther20038114315012842437
   PubMed Web of Science ®Google Scholar
• DerossiDCalvetSTrembleauABrunissenAChassaingGProchiantzACell internalization of the third helix of the Antennapedia homeodomain is receptor-independentJ Biol Chem19962713018188181938663410
   PubMed Web of Science ®Google Scholar
• KurtenRCSorting motifs in receptor traffickingAdv Drug Deliv Rev200355111405141914597138
   PubMed Web of Science ®Google Scholar
• HasegawaSHirashimaNNakanishiMMicrotubule involvement in the intracellular dynamics for gene transfection mediated by cationic liposomesGene Ther20018211669167311895006
   PubMed Web of Science ®Google Scholar
• LeslieEMDeeleyRGColeSPMultidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defenseToxicol Appl Pharmacol2005204321623715845415
   PubMed Web of Science ®Google Scholar
• SharomFJABC multidrug transporters: structure, function and role in chemoresistancePharmacogenomics20089110512718154452
   PubMed Web of Science ®Google Scholar
• ZhangLStrongJMQiuWLeskoLJHuangSMScientific perspectives on drug transporters and their role in drug interactionsMol Pharm200631626916686370
   PubMed Web of Science ®Google Scholar
• Lechapt-ZalcmanEHurbainILacaveRMDR1-Pgp 170 expression in human bronchusEur Respir J1997108183718439272928
   PubMed Web of Science ®Google Scholar
• SchefferGLPijnenborgACSmitEFMultidrug resistance related molecules in human and murine lungJ Clin Pathol200255533233911986335
   PubMed Web of Science ®Google Scholar
• van der ValkPvan KalkenCKKetelaarsHDistribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues. Analysis with 3 monoclonal antibodies recognizing different epitopes of the P-glycoprotein moleculeAnn Oncol19901156641706611
   PubMed Web of Science ®Google Scholar
• Cordon-CardoCO’BrienJPBocciaJCasalsDBertinoJRMelamedMRExpression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissuesJ Histochem Cytochem1990389127712871974900
   PubMed Web of Science ®Google Scholar
• SchinkelAHJonkerJWMammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overviewAdv Drug Deliv Rev200355132912535572
   PubMed Web of Science ®Google Scholar
• HsiaTCLinCCWangJJHoSTKaoARelationship between chemotherapy response of small cell lung cancer and P-glycoprotein or multidrug resistance-related protein expressionLung2002180317317912177731
   PubMed Web of Science ®Google Scholar
• LallemandJYStovenVAnnereauJPInduction by antitumoral drugs of proteins that functionally complement CFTR: a novel therapy for cystic fibrosis?Lancet199735090797117129291908
   PubMed Web of Science ®Google Scholar
• NaumannNSiratskaOGahrMRosen-WolffAP-glycoprotein expression increases ATP release in respiratory cystic fibrosis cellsJ Cyst Fibros20054315716815964250
   PubMedGoogle Scholar
• YeSMacEachranDPHamiltonJWO’TooleGAStantonBAChemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin CifAm J Physiol Cell Physiol20082953C80781818650266
   PubMed Web of Science ®Google Scholar
• van der DeenMMarksHWillemseBWDiminished expression of multidrug resistance-associated protein 1 (MRP1) in bronchial epithelium of COPD patientsVirchows Arch2006449668268817072643
   PubMed Web of Science ®Google Scholar
• BlokzijlHVander BorghtSBokLIDecreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levelsInflamm Bowel Dis200713671072017262809
   PubMed Web of Science ®Google Scholar
• HenrikssonGNorlanderTZhengXStiernaPWestrinKMExpression of P-glycoprotein 170 in nasal mucosa may be increased with topical steroidsAm J Rhinol19971143173219292183
   PubMedGoogle Scholar
• DemeuleMJodoinJBeaulieuEBrossardMBeliveauRDexamethasone modulation of multidrug transporters in normal tissuesFEBS Lett19994422–32082149929003
   PubMed Web of Science ®Google Scholar
• Dinis-OliveiraRJDuarteJARemiaoFSanchez-NavarroABastosMLCarvalhoFSingle high dose dexamethasone treatment decreases the pathological score and increases the survival rate of paraquat-intoxicated ratsToxicology20062271–2738516956706
   PubMed Web of Science ®Google Scholar
• SparreboomAvan AsperenJMayerULimited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestineProc Natl Acad Sci U S A1997945203120359050899
   PubMed Web of Science ®Google Scholar
• LangmannTMauererRZahnAReal-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissuesClin Chem200349223023812560344
   PubMed Web of Science ®Google Scholar
• KoolMde HaasMSchefferGLAnalysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell linesCancer Res19975716353735479270026
   PubMed Web of Science ®Google Scholar
• FlensMJZamanGJvan der ValkPTissue distribution of the multidrug resistance proteinAm J Pathol19961484123712478644864
   PubMed Web of Science ®Google Scholar
• BrechotJMHurbainIFajacADatyNBernaudinJFDifferent pattern of MRP localization in ciliated and basal cells from human bronchial epitheliumJ Histochem Cytochem19984645135179524197
   PubMed Web of Science ®Google Scholar
• van der DeenMde VriesEGVissermanHCigarette smoke extract affects functional activity of MRP1 in bronchial epithelial cellsJ Biochem Mol Toxicol200721524325117912704
   PubMed Web of Science ®Google Scholar
• van der DeenMHomanSTimmer-BosschaHEffect of COPD treatments on MRP1-mediated transport in bronchial epithelial cellsInt J Chron Obstruct Pulmon Dis20083346947518990976
   PubMedGoogle Scholar
• BleasbyKCastleJCRobertsCJExpression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug dispositionXenobiotica20063610–1196398817118916
   PubMed Web of Science ®Google Scholar
• HorvathGMendesESSchmidNThe effect of corticosteroids on the disposal of long-acting beta2-agonists by airway smooth muscle cellsJ Allergy Clin Immunol200712051103110917920670
   PubMed Web of Science ®Google Scholar
• LipsKSVolkCSchmittBMPolyspecific cation transporters mediate luminal release of acetylcholine from bronchial epitheliumAm J Respir Cell Mol Biol2005331798815817714
   PubMed Web of Science ®Google Scholar
• HorvathGSchmidNFragosoMAEpithelial organic cation transporters ensure pH-dependent drug absorption in the airwayAm J Respir Cell Mol Biol2007361536016917073
   PubMed Web of Science ®Google Scholar
• KummerWLipsKSPfeilUThe epithelial cholinergic system of the airwaysHistochem Cell Biol2008130221923418566825
   PubMed Web of Science ®Google Scholar
• KummerWWiegandSAkinciSRole of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouseJ Mol Neurosci2006301–2676817192631
   PubMed Web of Science ®Google Scholar
• GronebergDAFischerAChungKFDanielHMolecular mechanisms of pulmonary peptidomimetic drug and peptide transportAm J Respir Cell Mol Biol200430325126014969997
   PubMed Web of Science ®Google Scholar
• SondergaardHBBrodinBNielsenCUhPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3Pflugers Arch2008456361162218094991
   PubMed Web of Science ®Google Scholar
• GronebergDAEynottPRDoringFDistribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lungThorax2002571556011809991
   PubMed Web of Science ®Google Scholar
• EndterSFrancombeDEhrhardtCGumbletonMRT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell modelsJ Pharm Pharmacol200961558359119405996
   PubMed Web of Science ®Google Scholar
• SaitoHTeradaTOkudaMSasakiSInuiKMolecular cloning and tissue distribution of rat peptide transporter PEPT2Biochim Biophys Acta1996128021731778639691
   PubMed Web of Science ®Google Scholar
• BosquillonCDrug transporters in the lung – do they play a role in the biopharmaceutics of inhaled drugs?J Pharm Sci20109952240225519950388
   PubMed Web of Science ®Google Scholar
• MiyazakiHSekineTEndouHThe multispecific organic anion transporter family: properties and pharmacological significanceTrends Pharmacol Sci2004251265466215530644
   PubMed Web of Science ®Google Scholar
• HagenbuchBGuiCXenobiotic transporters of the human organic anion transporting polypeptides (OATP) familyXenobiotica2008387–877880118668430
   PubMed Web of Science ®Google Scholar
• AdachiHSuzukiTAbeMMolecular characterization of human and rat organic anion transporter OATP-DAm J Physiol Renal Physiol20032856F1188119714631946
   PubMed Web of Science ®Google Scholar
• HitzmanCJElmquistWFWiedmannTSDevelopment of a respirable, sustained release microcarrier for 5-fluorouracil II: In vitro and in vivo optimization of lipid coated nanoparticlesJ Pharm Sci20069551127114316570303
   PubMed Web of Science ®Google Scholar
• HitzmanCJElmquistWFWattenbergLWWiedmannTSDevelopment of a respirable, sustained release microcarrier for 5-fluorouracil I: In vitro assessment of liposomes, microspheres, and lipid coated nanoparticlesJ Pharm Sci20069551114112616570302
   PubMed Web of Science ®Google Scholar
• LiangHFChenCTChenSCPaclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancerBiomaterials20062792051205916307794
   PubMed Web of Science ®Google Scholar
• MusumeciTVicariLVenturaCAGulisanoMPignatelloRPuglisiGLyoprotected nanosphere formulations for paclitaxel controlled deliveryJ Nanosci Nanotechnol200669–103118312517048526
   PubMed Web of Science ®Google Scholar
• KhalidMNSimardPHoarauDDragomirALerouxJCLong circulating poly(ethylene glycol)-decorated lipid nanocapsules deliver docetaxel to solid tumorsPharm Res200623475275816550475
   PubMed Web of Science ®Google Scholar
• StinchcombeTENanoparticle albumin-bound paclitaxel: a novel Cremphor-EL-free formulation of paclitaxelNanomedicine (Lond)20072441542317716129
   PubMed Web of Science ®Google Scholar
• AggarwalANAgarwalRThe new ATS/ERS guidelines for assessing the spirometric severity of restrictive lung disease differ from previous standardsRespirology200712575976217875068
   PubMed Web of Science ®Google Scholar
• KreiderMEGrippiMAImpact of the new ATS/ERS pulmonary function test interpretation guidelinesRespir Med2007101112336234217686622
   PubMed Web of Science ®Google Scholar
• LawsonKAAndersonKMenchacaMNovel vitamin E analogue decreases syngeneic mouse mammary tumor burden and reduces lung metastasisMol Cancer Ther20032543744412748305
   PubMed Web of Science ®Google Scholar
• KnightVAnticancer effect of an alpha-TEA liposome aerosolExp Biol Med (Maywood)2005230529115855295
   PubMed Web of Science ®Google Scholar
• KnightVKoshkinaNVWaldrepJCGiovanellaBCGilbertBEAnticancer effect of 9-nitrocamptothecin liposome aerosol on human cancer xenografts in nude miceCancer Chemother Pharmacol199944317718610453718
   PubMed Web of Science ®Google Scholar
• GagnadouxFLeblondVVecellioLGemcitabine aerosol: in vitro antitumor activity and deposition imaging for preclinical safety assessment in baboonsCancer Chemother Pharmacol200658223724416328414
   PubMed Web of Science ®Google Scholar
• GagnadouxFLe PapeAUrbanTSafety of pulmonary administration of gemcitabine in ratsJ Aerosol Med200518219820615966774
   PubMedGoogle Scholar
• LemarieEVecellioLHureauxJAerosolized gemcitabine in patients with carcinoma of the lung: feasibility and safety studyJ Aerosol Med Pulm Drug Deliv201124626127021793717
   PubMed Web of Science ®Google Scholar
• MinRLiTDuJZhangYGuoJLuWLPulmonary gemcitabine delivery for treating lung cancer: pharmacokinetics and acute lung injury aspects in animalsCan J Physiol Pharmacol200886528829818432290
   PubMed Web of Science ®Google Scholar
• CamusPKudohSEbinaMInterstitial lung disease associated with drug therapyBr J Cancer200491Suppl 2S182315340374
   PubMed Web of Science ®Google Scholar
• CamusPInterstitial lung disease in patients with non-small-cell lung cancer: causes, mechanisms and managementBr J Cancer200491Suppl 2S1215340371
   PubMed Web of Science ®Google Scholar
• CamusPFantonABonniaudPCamusCFoucherPInterstitial lung disease induced by drugs and radiationRespiration200471430132615316202
   PubMed Web of Science ®Google Scholar
• MeradMLe CesneABaldeyrouPMesurolleBLe ChevalierTDocetaxel and interstitial pulmonary injuryAnn Oncol1997821911949093730
   PubMed Web of Science ®Google Scholar
• PavlakisNBellDRMillwardMJLeviJAFatal pulmonary toxicity resulting from treatment with gemcitabineCancer19978022862919217042
   PubMed Web of Science ®Google Scholar
• RabinowitsGHerchenhornDRabinowitsMWeatgeDTorresWFatal pulmonary toxicity in a patient treated with gefitinib for non-small cell lung cancer after previous hemolytic-uremic syndrome due to gemcitabineAnticancer Drugs200314866566814501391
   PubMed Web of Science ®Google Scholar
• SuzukiHAoshibaKYokohoriNNagaiAEpidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosisCancer Res200363165054505912941834
   PubMed Web of Science ®Google Scholar
• HajosFStarkBHenslerSPrasslRMosgoellerWInhalable liposomal formulation for vasoactive intestinal peptideInt J Pharm20083571–228629418328650
   PubMed Web of Science ®Google Scholar
• PakunluRIWangYTsaoWPozharovVCookTJMinkoTEnhancement of the efficacy of chemotherapy for lung cancer by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense: novel multicomponent delivery systemCancer Res200464176214622415342407
   PubMed Web of Science ®Google Scholar
• PakunluRICookTJMinkoTSimultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicinPharm Res200320335135912669953
   PubMed Web of Science ®Google Scholar
• PakunluRIWangYSaadMKhandareJJStarovoytovVMinkoTIn vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and anticancer drugJ Control Release2006114215316216889867
   PubMed Web of Science ®Google Scholar