59
Views
9
CrossRef citations to date
0
Altmetric
Original Research

A novel EGFR-targeted gene delivery system based on complexes self-assembled by EGF, DNA, and activated PAMAM dendrimers

, , , , &
Pages 4625-4635 | Published online: 24 Aug 2012

References

  • GilliesERFrechetJMDendrimers and dendritic polymers in drug deliveryDrug Discov Today2005101354315676297
  • SampathkumarSGYaremaKJTargeting cancer cells with dendrimersChem Biol20051215615664507
  • FangJNakamuraHMaedaHThe EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effectAdv Drug Deliv Rev201163313615120441782
  • TorchilinVTumor delivery of macromolecular drugs based on the EPR effectAdv Drug Deliv Rev201163313113520304019
  • PetrosRADeSimoneJMStrategies in the design of nanoparticles for therapeutic applicationsNat Rev Drug Discov20109861562720616808
  • DuncanRIzzoLDendrimer biocompatibility and toxicityAdv Drug Deliv Rev200557152215223716297497
  • LeeCCMacKayJAFrechetJMSzokaFCDesigning dendrimers for biological applicationsNat Biotechnol200523121517152616333296
  • EsfandRTomaliaDAPoly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applicationsDrug Discov Today20016842743611301287
  • MamedeMSagaTIshimoriTHepatocyte targeting of 111 In-labeled oligo-DNA with avidin or avidin-dendrimer complexJ Control Release200495113314115013240
  • SvensonSTomaliaDADendrimers in biomedical applications – reflections on the fieldAdv Drug Deliv Rev200557152106212916305813
  • ZhangYSunYXuXSynthesis, biodistribution, and microsingle photon emission computed tomography (SPECT) imaging study of technetium-99m labeled PEGylated dendrimer poly(amidoamine) (PAMAM)-folic acid conjugatesJ Med Chem20105383262327220350006
  • PillaiVCYesudasRShaikIHDelivery of NADPH-cytochrome P450 reductase antisense oligos using avidin-biotin approachBioconjug Chem201021220320720063878
  • VlasovGPLesinaEAKorol’kovVIOptimization of transfection properties of DNA-lysine dendrimer complexesBioorg Khim200531216717415889791
  • ChoiJSParkJSSupramolecular self-assembly of poly(ethylene glycol)-block-poly (L-lysine) dendrimer with plasmid DNAMethods Mol Med200165233321318743
  • FroehlichEMandevilleJSWeinertCMKreplakLTajmir-RiahiHABundling and aggregation of DNA by cationic dendrimersBiomacromolecules201112251151721192723
  • FroehlichEMandevilleJSKreplakLTajmir-RiahiHAAggregation and particle formation of tRNA by dendrimersBiomacromolecules20111272780278721574643
  • FroehlichEMandevilleJSArnoldDKreplakLTajmir-RiahiHAEffect of PEG and mPEG-anthracene on tRNA aggregation and particle formationBiomacromolecules201213128228722176277
  • NavarroGTros de IlarduyaCActivated and non-activated PAMAM dendrimers for gene delivery in vitro and in vivoNanomedicine20095328729719523431
  • KuoJHLiouMJChiuHCEvaluating the gene-expression profiles of HeLa cancer cells treated with activated and nonactivated poly(amidoamine) dendrimers, and their DNA complexesMol Pharm20107380581420394435
  • KandalaPKWrightSESrivastavaSKBlocking EGFR activation suppresses ovarian tumor growth in vitro and in vivoJ Pharmacol Exp Ther2012341243222205686
  • FrederiksenKSAbrahamsenNCristianoRJDamstrupLPoulsenHSGene delivery by an epidermal growth factor/DNA polyplex to small cell lung cancer cell lines expressing low levels of epidermal growth factor receptorCancer Gene Ther20007226226810770635
  • ChenJGamouSTakayanagiAOhtakeYOhtsuboMShimizuNReceptor-mediated gene delivery using the Fab fragments of anti-epidermal growth factor receptor antibodies: improved immunogene approachCancer Gene Ther1998563573649917090
  • YuanQLeeEYeudallWAYangHDendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug deliveryOral Oncol201046969870420729136
  • SebastianSSettlemanJReshkinSJAzzaritiABellizziAParadisoAThe complexity of targeting EGFR signalling in cancer: from expression to turnoverBiochim Biophys Acta20061766112013916889899
  • ThomasTPShuklaRKotlyarADendrimer-epidermal growth factor conjugate displays superagonist activityBiomacromolecules20089260360918193839
  • ZhangQChenSZhuoRXZhangXZChengSXSelf-assembled terplexes for targeted gene delivery with improved transfectionBioconjug Chem201021112086209220931957
  • KrugerJSReddyKBDistinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cellsMol Cancer Res200311180180914517342
  • ShcharbinDPedziwiatrEBryszewskaMHow to study dendriplexes I: CharacterizationJ Control Release2009135318619719331857
  • MounkesLCZhongWCipres-PalacinGHeathTDDebsRJProteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivoJ Bio Chem19982734026164261709748298
  • MislickKABaldeschwielerJDEvidence for the role of proteoglycans in cation-mediated gene transferProc Natl Acad Sci U S A1996932212349123548901584
  • TangMXRedemannCTSzokaFCJrIn vitro gene delivery by degraded polyamidoamine dendrimersBioconjug Chem1996767037148950489
  • AndersonNGAhmadTChanKDobsonRBundredNJZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the ngrowth of EGFR-positive cancer cell lines with or without erbB2 overexpressionInt J Cancer200194677478211745477
  • DuncanRPolymer conjugates for tumour targeting and intracytoplasmic delivery. The EPR effect as a common gateway?Pharm Sci Technolo Today199921144144910542390
  • ZelphatiOUyechiLSBarronLGSzokaFCJrEffect of serum components on the physico-chemical properties of cationic lipid/oligonucleotide complexes and on their interactions with cellsBiochim Biophys Acta1998139021191339507083