Gene-carried hepatoma targeting complex induced high gene transfection efficiency with low toxicity and significant antitumor activity

References

• Cavazzana-CalvoMHacein-BeySde Saint BasileGGene therapy of human severe combined immunodeficiency (SCID)-X1 diseaseScience2000288546666967210784449
   PubMed Web of Science ®Google Scholar
• BoydACGene and stem cell therapyBushAAltonEWFWDaviesJCGriesenbachUJaffeACystic Fibrosis in the 21st CenturyBaselKarger2006221232
   Google Scholar
• KaplittMGFeiginATangCSafety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson’s disease: an open label, phase I trialLancet200736995792097210517586305
   PubMed Web of Science ®Google Scholar
• YangZRWangHFZhaoJRecent developments in the use of adenoviruses and immunotoxins in cancer gene therapyCancer Gene Ther200714759961517479105
   PubMed Web of Science ®Google Scholar
• AndersonWFHuman gene therapyNature1998392667925309579858
   PubMed Web of Science ®Google Scholar
• PackDWHoffmanASPunSStaytonPSDesign and development of polymers for gene deliveryNat Rev Drug Discov20054758159316052241
   PubMed Web of Science ®Google Scholar
• VermaIMSomiaNGene therapy – promises, problems and prospectsNature199738966482392429305836
   PubMed Web of Science ®Google Scholar
• Koping-HoggardMVarumKMIssaMImproved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomersGene Ther200411191441145215269712
   PubMed Web of Science ®Google Scholar
• KimTHKimSIAkaikeTChoCSSynergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexesJ Control Release2005105335436615949861
   PubMed Web of Science ®Google Scholar
• DensmoreCLOrsonFMXuBAerosol delivery of robust polyethyleneimine-DNA complexes for gene therapy and genetic immunizationMol Ther20001218018810933929
   PubMed Web of Science ®Google Scholar
• KichlerALeborgneCDanosODilution of reporter gene with stuffer DNA does not alter the transfection efficiency of polyethyleniminesJ Gene Med20057111459146716041686
   PubMed Web of Science ®Google Scholar
• FischerDBieberTLiYElsasserHPKisselTA novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicityPharm Res19991681273127910468031
   PubMed Web of Science ®Google Scholar
• KunathKvon HarpeAFischerDKisselTGalactose-PEI-DNA complexes for targeted gene delivery: degree of substitution affects complex size and transfection efficiencyJ Control Release200388115917212586513
   PubMed Web of Science ®Google Scholar
• GaoJQZhaoQQLvTFGene-carried chitosan-linked-PEI induced high gene transfection efficiency with low toxicity and significant tumor-suppressive activityInt J Pharm20103871–228629420035848
   PubMed Web of Science ®Google Scholar
• ZhaoQQChenJLLvTFN/P ratio significantly influences the transfection efficiency and cytotoxicity of a polyethylenimine/chitosan/ DNA complexBiol Pharm Bull200932470671019336909
   PubMed Web of Science ®Google Scholar
• ParkIKParkYHShinBAGalactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrierJ Control Release20006919710811018549
   PubMed Web of Science ®Google Scholar
• ParkMRKimHWHwangCSHighly efficient gene transfer with degradable poly(ester amine) based on poly(ethylene glycol) diacrylate and polyethylenimine in vitro and in vivoJ Gene Med200810219820718064729
   PubMed Web of Science ®Google Scholar
• ZhangCGaoSJiangWTargeted minicircle DNA delivery using folate-poly(ethylene glycol)-polyethylenimine as non-viral carrierBiomaterials201031236075608620488533
   PubMed Web of Science ®Google Scholar
• BonoiuACMahajanSDDingHNanotechnology approach for drug addiction therapy: gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neuronsProc Natl Acad Sci U S A2009106145546555019307583
   PubMed Web of Science ®Google Scholar
• ZhangBZhangYWangJScreening and identification of a targeting peptide to hepatocarcinoma from a phage display peptide libraryMol Med2007135–624625417622312
   PubMed Web of Science ®Google Scholar
• FarhoodHBottegaREpandRMHuangLEffect of cationic cholesterol derivatives on gene transfer and protein kinase C activityBiochim Biophys Acta1992111122392461420259
   PubMed Web of Science ®Google Scholar
• KopatzIRemyJSBehrJPA model for non-viral gene delivery: through syndecan adhesion molecules and powered by actinJ Gene Med20046776977615241784
   PubMed Web of Science ®Google Scholar
• FengMLeeDLiPIntracellular uptake and release of poly (ethyleneimine)-co-poly(methyl methacrylate) nanoparticle/ pDNA complexes for gene deliveryInt J Pharm20063111–220921416442245
   PubMed Web of Science ®Google Scholar
• HashimotoMMorimotoMSaimotoHShigemasaYSatoTLactosylated chitosan for DNA delivery into hepatocytes: the effect of lactosylation on the physicochemical properties and intracellular trafficking of pDNA/chitosan complexesBioconjug Chem200617230931616536460
   PubMed Web of Science ®Google Scholar
• ColomboMPTrinchieriGInterleukin-12 in anti-tumor immunity and immunotherapyCytokine Growth Factor Rev200213215516811900991
   PubMed Web of Science ®Google Scholar
• ManettiRParronchiPGiudiziMGNatural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cellsJ Exp Med19931774119912048096238
   PubMed Web of Science ®Google Scholar
• ManettiRGerosaFGiudiziMGInterleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clonesJ Exp Med19941794127312837908322
   PubMed Web of Science ®Google Scholar
• Del VecchioMBajettaECanovaSInterleukin-12: biological properties and clinical applicationClin Cancer Res200713164677468517699845
   PubMed Web of Science ®Google Scholar
• BerraondoPPrietoJGonzalez-AseguinolazaGAdvances in interleukin- 12 gene therapy for acquired liver diseasesCurr Gene Ther200992627119355864
   PubMed Web of Science ®Google Scholar