Synthesis and Characterization of a Cationic Thiomer Based on Ethyl Cellulose for Realization of Mucoadhesive Tablets and Nanoparticles

References

• Soppimath KS, Aminabhavi TM, Kulkarni AR, Rudzinski WE. Biodegradable polymeric nanoparticles as drug delivery devices. J Control Release. 2001;70:1–20. doi:10.1016/s0168-3659(00)003339-4
   PubMed Web of Science ®Google Scholar
• Kumari A, Yadav SK. Cellular interactions of therapeutically delivered nanoparticles. Exp Opinion Drug Deliv. 2011;8:141–151. doi:10.1517/17425247.2011.547934
   PubMed Web of Science ®Google Scholar
• Iman K, Jafari SM. Nano-encapsulation as a promising approach for targeted delivery and controlled release of vitamins. Trends Food Sci Technol. 2016;53:34–48. doi:10.1016/j.tifs.2016.05.002
   Web of Science ®Google Scholar
• Naveen NR, Gopinath C, Kurakula M. Okra-thioglycolic acid conjugate-synthesis, characterization, and evaluation as a mucoadhesive polymer. Processes. 2020;8(316):1–19. doi:10.3390/pr8030316
   Web of Science ®Google Scholar
• Yang D, Chen W, Hu J. Design of controlled drug delivery system based on disulfide cleavage trigger. J Phys Chem B. 2014;118:12311–12317. doi:10.1021/jp507763a
   PubMed Web of Science ®Google Scholar
• Rahmat D, Rahman FAR, Nurhidayati L, Laksmitawati DR. Synthesis and characterization of hydroxypropyl cellulose-cysteamine conjugate as a novel cationic thiomer with lipophilic properties. Int J App Pharm. 2019;11:222–226. doi:10.22159/ijap.2019v11i1.30014
   PubMedGoogle Scholar
• Santana SP, Salazar NF. Ionotropic gelation method in the synthesis of nano/microparticles for biomedical purposes. Polym Int. 2020;69:443–447. doi:10.1002/pi.5970
   Web of Science ®Google Scholar
• Rahmat D, Müller C, Barthelmes J, Shahnaz G, Martien R, Schnürch AB. Thiolated hydroxyethyl cellulose: design and in vitro evaluation of mucoadhesive and permeation enhancing nanoparticles. Eur J Pharm Biopharm. 2013;83:149–155. doi:10.1016/j.ejpb.2012.10.008
   PubMed Web of Science ®Google Scholar
• Rahmat D, Sakloetsakun D, Shahnaz G, Perera G, Kaindl R, Schnurch AB. Design and synthesis of a novel cationic thiolated polymer. Int J Pharm. 2011;411:10–17. doi:10.1016/j.ijpharm.2011.02.063
   PubMed Web of Science ®Google Scholar
• Hassan EE, Gallo JJ. A simple rheological method for the in vitro assessment of mucin-polymer bioadhesive bond strength. Pharm Res. 1990;7:491–495. doi:10.1023/A:1015812615635
   PubMed Web of Science ®Google Scholar
• Bondar RJL, Mead DC. Evaluation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides in the hexokinase method for determining glucose in serum. Clin Chem. 1974;20:586–590. doi:10.1093/clinchem/20.5.586
   PubMed Web of Science ®Google Scholar
• Iqbal J, Shahnaz G, Dünnhaupt S, Müller C, Bernkop-Schnürch A. Preactivated thiomer as mucoadhesive polymers for drug delivery. Biomaterials. 2012;33:1528–1535. doi:10.1016/j.biomaterials.2011.10.021
   PubMed Web of Science ®Google Scholar
• Jonderian A, Maalouf R. Formulation and in vitro interaction of rhodamine-b loaded PLGA nanoparticles with cardiac myocyte. Front Pharmacol. 2016;7:1–7. doi:10.3389/fphar.2016.00458
   PubMed Web of Science ®Google Scholar
• Balzus B, Colombo M, Sahle FF, Zoubari G, Staufenbiel S, Bodmeier R. Comparison of different in vitro release methods used to investigate nanocarriers intended for dermal application. Int J Pharm. 2016;513:247–254. doi:10.1016/j.ijpharm.2016.09.033
   PubMed Web of Science ®Google Scholar
• Sarti F, Iqbal J, Müller C, Shahnaz G, Rahmat D, Schnürch AB. Poly(acrylic acid)–cysteine for oral vitamin b12 delivery. Anal Biochem. 2013;420:13–19. doi:10.1016/j.ab.2011.08.039
   Web of Science ®Google Scholar
• Ito T, Yeo Y, Highley CB, Bellas E, Benitez CA, Kohane DS. The prevention of peritoneal adhesions by in situ cross-linking hydrogels of hyaluronic acid and cellulose derivatives. Biomaterials. 2007;28:975–983. doi:10.1016/j.biomaterials.2006.10.021
   PubMed Web of Science ®Google Scholar
• Crespin L, Biancalana L, Morack T, Blakemore DC, Ley SV. One-pot acid-catalyzed ring-opening/cyclization/oxidation of aziridines with N‑tosylhydrazones: access to 1,2,4-triazines. Org Lett. 2017;19:1084–1087. doi:10.1021/acs.orglett.7b00101
   PubMed Web of Science ®Google Scholar
• Abdel-Magid AF, Carson KG, Harris BD, Maryanoff CA, Shah RD. Reductive amination of aldehydes and ketones with sodium triacetoxyborohydride: studies on direct and indirect reductive amination procedures (1). J Org Chem. 1996;61:3849–3862. doi:10.1021/jo960057x
   PubMed Web of Science ®Google Scholar
• Tadanier J, Hallas R, Martin JR, Stanaszek RS. Observation relevant to the mechanism of the reductive aminations of ketones with sodium cyanoborohydride and ammonium acetate. Tetrahedron. 1981;37:1309–1316. doi:10.1016/S0040-4020(01
   Web of Science ®Google Scholar
• Pletz J, Berg B, Breinbauer RA. General and direct reductive amination of aldehydes and ketones with electron-deficient anilines. Synthesis. 2016;48:1301–1317. doi:10.1055/s-0035-1561384
   Web of Science ®Google Scholar
• Hombach J, Palmberger TF, Schnürch AB. Development and in vitro evaluation of a mucoadhesive vaginal delivery system for nystatin. J Pharm Sci. 2009;98:555–564. doi:10.1002/jps.21457
   PubMed Web of Science ®Google Scholar
• Schnürch AB. Thiomers: a new generation of mucoadhesive polymers. Adv Drug Deliv Rev. 2005;57:1569–1582. doi:10.1016/j.addr.2005.07.002
   PubMed Web of Science ®Google Scholar
• Roldo R, Hornof M, Caliceti P, Schnürch AB. Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: synthesis and in vitro evaluation. Eur J Pharm Biopharm. 2004;57:115–121. doi:10.1016/s0939-6411(03)00157-7
   PubMed Web of Science ®Google Scholar
• Jadhav NR, Gaikwad VL, Nair KJ, Kadam HM. Glass transition temperature: basics and application in pharmaceutical sector. Asian J Pharm Sci. 2009;3:82–89. doi:10.4103/0973-8398.55043
   Google Scholar
• Gombas A, Szabó-Révész P, Kata M, Regdon JG, Erõs I. Quantitative determination of crystallinity of a-lactose monohydrate by dsc. J Therm Anal Calorim. 2002;68:503–510. doi:10.1023/A:1016039819247
   Web of Science ®Google Scholar
• Erikstein BS, Hagland HR, Nikolaisen J, et al. Cellular stress induced by resazurin leads to autophagy and cell death via production of reactive oxygen species and mitochondrial impairment. J Cell Biochem. 2010;111:574–584. doi:10.1002/jcb.22741
   PubMed Web of Science ®Google Scholar
• Borra RC, Lotufo MA, Gagioti SM, Barros FDM, Andrade PM. A simple method to measure cell viability in proliferation and cytotoxicity assays. Braz Oral Res. 2009;23:255–562. doi:10.1002/jcb.22741
   PubMed Web of Science ®Google Scholar
• Melzera E, Kreuterb J, Danielsa R. Ethylcellulose: a new type of emulsion stabilizer. Eur J Pharm Biopharm. 2003;56:23–27. doi:10.1016/s0939-6411(03)00025-0
   PubMed Web of Science ®Google Scholar