89
Views
11
CrossRef citations to date
0
Altmetric
Original Research

Selective cytotoxicity of PAMAM G5 core–PAMAM G2.5 shell tecto-dendrimers on melanoma cells

, , &
Pages 4121-4133 | Published online: 31 Jul 2012

References

  • BhuleierEWehnerWVögtleF“Cascade”- and “nonskid-chain-like” syntheses of molecular cavity topologiesSynthesis19782155158
  • TomaliaDABakerHDewaldJA new class of polymers: starburst-dendritic macromoleculesPolym J198517117132
  • RobertsJCBhalgatMKZeraRTPreliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimersJ Biomed Mater Res199630153658788106
  • MalikNWiwattanapatapeeRKlopschRDendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivoJ Control Release2000651–213314810699277
  • GreishKThiagarajanGHerdHSize and surface charge significantly influence the toxicity of silica and dendritic nanoparticlesNanotoxicology Epub July 28, 2011
  • HawkerCJFréchetJMJPreparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromoleculesJ Am Chem Soc199011276387647
  • Lothian-TomaliaMKHedstrandDMTomaliaDAPadiasABHallHKJrA contemporary survey of covalent connectivity and complexity. The divergent synthesis of poly(thioether) dendrimers. Amplified, genealogically directed synthesis leading to the de Gennes dense packed stateTetrahedron1997531549515513
  • de GennesPGHervetHJStatistics of “starburst” polymersEurophys Lett198344351360
  • TomaliaDAUppuluriSSwansonDRLiJDendrimers as reactive modules for the synthesis of new structure-controlled, higher-complexity megamersPure Appl Chem20007223432358
  • TomaliaDAHedstrandDMWilsonLRDendritic polymersMarkHFBikalesNOverbergerCGMengesGEncylopedia of Polymer Science and EngineeringNew YorkWiley19904692
  • UppuluriSPiehlerLTLiJSwansonDRHagnauerGLTomaliaDACore-shell tecto(dendrimers): I. Synthesis and characterization of saturated shell modelsAdv Mater200012796800
  • LiJSwansonDRQinDCharacterizations of core−shell tecto-(dendrimer) molecules by tapping mode atomic force microscopyLangmuir19991573477350
  • TomaliaDABrothersHM2ndPiehlerLTDurstHDSwansonDRPartial shell-filled core-shell tecto(dendrimers): a strategy to surface differentiated nano-clefts and cuspsProc Natl Acad Sci U S A20029985081508711943851
  • KitchensKMKolhatkarRBSwaanPWEddingtonNWGhandehariHTransport of poly(amidoamine) dendrimers across caco-2 cell monolayers: influence of size, charge and fluorescent labelingPharm Res2006232818282617094034
  • JevprasesphantRPennyJAttwoodDMcKeownNBD’EmanueleAEngineering of dendrimer surfaces to enhance transepithelial transport and reduce cytotoxicityPharm Res200320101543155014620505
  • RahmanIKodeABiswasSKAssay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling methodNat Protoc2006163159316517406579
  • BradfordMMA rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnal Biochem197672248254942051
  • JasmineMAPrasadEFractal growth of PAMAM dendrimer aggregates and its impact on the intrinsic emission propertiesJ Phys Chem B20101147735774220496918
  • LiJPiehlerLTQinDBakerJRJrTomaliaDAVisualization and characterization of poly(amidoamine) dendrimers by atomic force microscopyLangmuir20001656135616
  • BetleyTABanaszak HollMMOrrBGSwansonDRTomaliaDABakerJJRTapping mode atomic force microscopy investigation of poly(amidoamine) dendrimers: effects of substrate and pH on dendrimer deformationLangmuir20011727682773
  • ShiXPatriAKLesniakWAnalysis of poly(amidoamine)-succinamic acid dendrimers by slab-gel electrophoresis and capillary zone electrophoresisElectrophoresis2005262960296716007703
  • BhadraDBhadraSJainSJainNKA PEGylated dendritic nanoparticulate carrier of fluorouracilInt J Pharm20032571–211112412711167
  • JevprasesphantRPennyJJalalRAttwoodDMcKeownNBD’EmanueleAThe influence of surface modification on the cytotoxicity of PAMAM dendrimersInt J Pharm20032521–226326612550802
  • El-SayedMGinskiMRhodesCGhandehariHTransepithelial transport of poly(amidoamine) dendrimers across Caco-2 cell monolayersJ Control Release200281335536512044574
  • El-SayedMRhodesCAGinskiMGhandehariHTransport mechanism(s) of poly(amidoamine) dendrimers across Caco-2 cell monolayersInt J Pharm20032651–215115714522128
  • KirkpatrickGJPlumbJASutcliffeOBFlintDJWheateNJEvaluation of anionic half generation 3.5–6.5 poly(amidoamine) dendrimers as delivery vehicles for the active component of the anticancer drug cisplatinJ Inorg Biochem201110591115112221704583
  • NordenbergJPanetCWassermanLThe anti-proliferative effect of lithium chloride on melanoma cells and its reversion by myo-inositolBr J Cancer198755141463028460
  • KaufmannLMarinescuGNazarenkoILiCl induces TNF-alpha and FasL production, thereby stimulating apoptosis in cancer cellsCell Commun Signal201191521609428
  • MatesJMEffects of antioxidant enzymes in the molecular control of reactive oxygen species toxicologyToxicology20001531–38310411090949
  • WangJZhouGChenCAcute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administrationToxicol Lett2007168217618517197136
  • BrownDMDonaldsonKBormPJCalcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particlesAm J Physiol Lung Cell Mol Physiol20042862L34435314555462
  • LeeJHChaKEKimMSNanosized polyamidoamine (PAMAM) dendrimer-induced apoptosis mediated by mitochondrial dysfunctionToxicol Lett2009190220220719643170
  • NahaPCDavorenMLyngFMByrneHJReactive oxygen species (ROS) induced cytokine production and cytotoxicity of PAMAM dendrimers in J774 A.1 cellsToxicol Appl Pharmacol20102461–2919920420846
  • MukherjeeSPLyngFMGarciaADavorenMByrneHJMechanistic studies of in vitro cytotoxicity of poly(amidoamine) dendrimers in mammalian cellsToxicol Appl Pharmacol2010248325926820736030
  • XiaTKovochichMBrantJComparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigmNano Lett2006681794180716895376
  • XiaTKovochichMLiongMZinkJINelAECationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathwaysACS Nano200821859619206551
  • MeyskensFLJrBuckmeierJAMcNultySETohidianNBActivation of nuclear factor-kappa B in human metastatic melanomacells and the effect of oxidative stressClin Cancer Res1999551197120210353757
  • MeyskensFLJrFarmerPFruehaufJPRedox regulation in human melanocytes and melanomaPigment Cell Res200114314815411434561
  • FarmerPJGidanianSShahandehBDi BilioAJTohidianNMeyskensFLJrMelanin as a target for melanoma chemotherapy: pro-oxidant effect of oxygen and metals on melanoma viabilityPigment Cell Res200316327327912753401
  • SnowETSykoraPDurhamTRKleinCBArsenic, mode of action at biologically plausible low doses: what are the implications for low dose cancer risk?Toxicol Appl Pharmacol2005207Suppl 255756415996700
  • SimonHUHaj-YehiaALevi-SchafferFRole of reactive oxygen species (ROS) in apoptosis inductionApoptosis2005541541811256882