Recent Progress of Metal-Organic Framework-Based Photodynamic Therapy for Cancer Treatment

References

• Dolmans DE, Fukumura D, Jain RK. Photodynamic therapy for cancer. Nat Rev Cancer. 2003;3(5):380–387. doi:10.1038/nrc1071
   PubMed Web of Science ®Google Scholar
• Stables GI, Ash DV. Photodynamic therapy. Cancer Treat Rev. 1995;21(4):311–323. doi:10.1016/0305-7372(95
   PubMed Web of Science ®Google Scholar
• Manyak MJ, Russo A, Smith PD, Glatstein E. Photodynamic therapy. J Clin Oncol. 1988;6(2):380–391. doi:10.1200/jco.1988.6.2.380
   PubMed Web of Science ®Google Scholar
• Zhen X, Cheng P, Pu K. Recent Advances in Cell Membrane-Camouflaged Nanoparticles for Cancer Phototherapy. Small. 2019;15(1):e1804105. doi:10.1002/smll.201804105
   PubMed Web of Science ®Google Scholar
• Perlman SG, Gerber LH, Roberts RM, Nigra TP, Barth WF. Photochemotherapy and psoriatic arthritis. A prospective study. Ann Intern Med. 1979;91(5):717–722. doi:10.7326/0003-4819-91-5-717
   PubMed Web of Science ®Google Scholar
• Huang R, Zhang C, Bu Y, et al. A multifunctional nano-therapeutic platform based on octahedral yolk-shell Au NR@CuS: photothermal/photodynamic and targeted drug delivery tri-combined therapy for rheumatoid arthritis. Biomaterials. 2021;277:121088. doi:10.1016/j.biomaterials.2021.121088
   PubMed Web of Science ®Google Scholar
• van Dijk EHC, Fauser S, Breukink MB, et al. Half-Dose Photodynamic Therapy versus High-Density Subthreshold Micropulse Laser Treatment in Patients with Chronic Central Serous Chorioretinopathy: the PLACE Trial. Ophthalmology. 2018;125(10):1547–1555. doi:10.1016/j.ophtha.2018.04.021
   PubMed Web of Science ®Google Scholar
• Dong Y, Cao W, Cao J. Treatment of rheumatoid arthritis by phototherapy: advances and perspectives. Nanoscale. 2021;13(35):14591–14608. doi:10.1039/d1nr03623h
   PubMed Web of Science ®Google Scholar
• Nam J, Son S, Ochyl LJ, Kuai R, Schwendeman A, Moon JJ. Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer. Nat Commun. 2018;9(1):1074. doi:10.1038/s41467-018-03473-9
   PubMed Web of Science ®Google Scholar
• Liang X, Chen M, Bhattarai P, Hameed S, Dai Z. Perfluorocarbon@Porphyrin Nanoparticles for Tumor Hypoxia Relief to Enhance Photodynamic Therapy against Liver Metastasis of Colon Cancer. ACS Nano. 2020;14(10):13569–13583. doi:10.1021/acsnano.0c05617
   PubMed Web of Science ®Google Scholar
• Donohoe C, Senge MO, Arnaut LG, Gomes-da-Silva LC. Cell death in photodynamic therapy: from oxidative stress to anti-tumor immunity. Biochimica Et Biophysica Acta Reviews Cancer. 2019;1872(2):188308. doi:10.1016/j.bbcan.2019.07.003
   PubMed Web of Science ®Google Scholar
• Fang J, Nakamura H, Iyer AK. Tumor-targeted induction of oxystress for cancer therapy. J Drug Target. 2007;15(7–8):475–486. doi:10.1080/10611860701498286
   PubMed Web of Science ®Google Scholar
• Chilakamarthi U, Giribabu L. Photodynamic Therapy: past, Present and Future. Chemical Record. 2017;17(8):775–802. doi:10.1002/tcr.201600121
   PubMed Web of Science ®Google Scholar
• Allison RR, Downie GH, Cuenca R, Hu XH, Childs CJ, Sibata CH. Photosensitizers in clinical PDT. Photodiagnosis Photodyn Ther. 2004;1(1):27–42. doi:10.1016/s1572-1000(04
   PubMed Web of Science ®Google Scholar
• Ethirajan M, Chen Y, Joshi P, Pandey RK. The role of porphyrin chemistry in tumor imaging and photodynamic therapy. Chem Soc Rev. 2011;40(1):340–362. doi:10.1039/b915149b
   PubMed Web of Science ®Google Scholar
• Staron J, Boron B, Karcz D, Szczygieł M, Fiedor L. Recent Progress in Chemical Modifications of Chlorophylls and Bacteriochlorophylls for the Applications in Photodynamic Therapy. Curr Med Chem. 2015;22(26):3054–3074. doi:10.2174/0929867322666150818104034
   PubMed Web of Science ®Google Scholar
• Li L, Shao C, Liu T, et al. An NIR-II-Emissive Photosensitizer for Hypoxia-Tolerant Photodynamic Theranostics. Adv Mater. 2020;32(45):e2003471. doi:10.1002/adma.202003471
   PubMed Web of Science ®Google Scholar
• Farokhzad OC, Langer R. Impact of nanotechnology on drug delivery. ACS Nano. 2009;3(1):16–20. doi:10.1021/nn900002m
   PubMed Web of Science ®Google Scholar
• Hossen S, Hossain MK, Basher MK, Mia MNH, Rahman MT, Uddin MJ. Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: a review. J Adv Res. 2019;15:1–18. doi:10.1016/j.jare.2018.06.005
   PubMed Web of Science ®Google Scholar
• Chen W, Goldys EM, Deng W. Light-induced liposomes for cancer therapeutics. Prog Lipid Res. 2020;79:101052. doi:10.1016/j.plipres.2020.101052
   PubMed Web of Science ®Google Scholar
• Li W, Yang J, Luo L, et al. Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death. Nat Commun. 2019;10(1):3349. doi:10.1038/s41467-019-11269-8
   PubMed Web of Science ®Google Scholar
• Yang Y, Wang L, Cao H, et al. Photodynamic Therapy with Liposomes Encapsulating Photosensitizers with Aggregation-Induced Emission. Nano Lett. 2019;19(3):1821–1826. doi:10.1021/acs.nanolett.8b04875
   PubMed Web of Science ®Google Scholar
• Sharma A, Liaw K, Sharma R, Zhang Z, Kannan S, Kannan RM. Targeting Mitochondrial Dysfunction and Oxidative Stress in Activated Microglia using Dendrimer-Based Therapeutics. Theranostics. 2018;8(20):5529–5547. doi:10.7150/thno.29039
   PubMed Web of Science ®Google Scholar
• Chung CH, Lu KY, Lee WC, et al. Fucoidan-based, tumor-activated nanoplatform for overcoming hypoxia and enhancing photodynamic therapy and antitumor immunity. Biomaterials. 2020;257:120227. doi:10.1016/j.biomaterials.2020.120227
   PubMed Web of Science ®Google Scholar
• Liang S, Sun C, Yang P, et al. Core-shell structured upconversion nanocrystal-dendrimer composite as a carrier for mitochondria targeting and catalase enhanced anti-cancer photodynamic therapy. Biomaterials. 2020;240:119850. doi:10.1016/j.biomaterials.2020.119850
   PubMed Web of Science ®Google Scholar
• Qindeel M, Khan D, Ahmed N, Khan S, Ur R. Surfactant-Free, Self-Assembled Nanomicelles-Based Transdermal Hydrogel for Safe and Targeted Delivery of Methotrexate against Rheumatoid Arthritis. ACS Nano. 2020;14(4):4662–4681. doi:10.1021/acsnano.0c00364
   PubMed Web of Science ®Google Scholar
• Cheng L, Kamkaew A, Sun H, et al. Dual-Modality Positron Emission Tomography/Optical Image-Guided Photodynamic Cancer Therapy with Chlorin e6-Containing Nanomicelles. ACS Nano. 2016;10(8):7721–7730. doi:10.1021/acsnano.6b03074
   PubMed Web of Science ®Google Scholar
• Li Y, Wu Q, Kang M, Song N, Wang D, Tang BZ. Boosting the photodynamic therapy efficiency by using stimuli-responsive and AIE-featured nanoparticles. Biomaterials. 2020;232:119749. doi:10.1016/j.biomaterials.2019.119749
   PubMed Web of Science ®Google Scholar
• Belali S, Savoie H, O’Brien JM, et al. Synthesis and Characterization of Temperature-Sensitive and Chemically Cross-Linked Poly(N-isopropylacrylamide)/Photosensitizer Hydrogels for Applications in Photodynamic Therapy. Biomacromolecules. 2018;19(5):1592–1601. doi:10.1021/acs.biomac.8b00293
   PubMed Web of Science ®Google Scholar
• Belali S, Karimi AR, Hadizadeh M. Cell-specific and pH-sensitive nanostructure hydrogel based on chitosan as a photosensitizer carrier for selective photodynamic therapy. Int J Biol Macromol. 2018;110:437–448. doi:10.1016/j.ijbiomac.2017.12.169
   PubMed Web of Science ®Google Scholar
• Yan J, Zhang Z, Zhan X, et al. In situ injection of dual-delivery PEG based MMP-2 sensitive hydrogels for enhanced tumor penetration and chemo-immune combination therapy. Nanoscale. 2021;13(21):9577–9589. doi:10.1039/d1nr01155c
   PubMed Web of Science ®Google Scholar
• Crommelin DJA, van Hoogevest P, Storm G. The role of liposomes in clinical nanomedicine development. J Control Release. 2020;318:256–263. doi:10.1016/j.jconrel.2019.12.023
   PubMed Web of Science ®Google Scholar
• D’Emanuele A, Attwood D. Dendrimer-drug interactions. Adv Drug Deliv Rev. 2005;57(15):2147–2162. doi:10.1016/j.addr.2005.09.012
   PubMed Web of Science ®Google Scholar
• Wu MX, Yang YW. Metal-Organic Framework (MOF)-Based Drug/Cargo Delivery and Cancer Therapy. Adv Mater. 2017;29:23. doi:10.1002/adma.201606134
   Web of Science ®Google Scholar
• Cai W, Wang J, Chu C, Chen W, Wu C, Liu G. Metal-Organic Framework-Based Stimuli-Responsive Systems for Drug Delivery. Advanced Science. 2019;6(1):98. doi:10.1002/advs.201801526
   Web of Science ®Google Scholar
• Zhang L, Gao Y, Sun S, Li Z, Wu A, Zeng L. pH-Responsive metal-organic framework encapsulated gold nanoclusters with modulated release to enhance photodynamic therapy/chemotherapy in breast cancer. J Mater Chem B. 2020;8(8):1739–1747. doi:10.1039/c9tb02621e
   PubMed Web of Science ®Google Scholar
• Zhang Y, Fu H, Chen S, Liu B, Sun W, Gao H. Construction of an iridium(iii)-complex-loaded MOF nanoplatform mediated with a dual-responsive polycationic polymer for photodynamic therapy and cell imaging. Chem Commun (Camb). 2020;56(5):762–765. doi:10.1039/c9cc09357e
   PubMed Web of Science ®Google Scholar
• Shen S, Wu Y, Liu Y, Wu D. High drug-loading nanomedicines: progress, current status, and prospects. Int J Nanomedicine. 2017;12:4085–4109. doi:10.2147/ijn.S132780
   PubMed Web of Science ®Google Scholar
• Cai W, Chu -C-C, Liu G, Wáng Y-XJ. Metal-Organic Framework-Based Nanomedicine Platforms for Drug Delivery and Molecular Imaging. Small. 2015;11(37):4806–4822. doi:10.1002/smll.201500802
   PubMed Web of Science ®Google Scholar
• Horcajada P, Chalati T, Serre C, et al. Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging. Nat Mater. 2009;9(2):172–178. doi:10.1038/nmat2608
   PubMed Web of Science ®Google Scholar
• Chen G, Leng X, Luo J, et al. In Vitro Toxicity Study of a Porous Iron(III) Metal‒Organic Framework. Molecules. 2019;24(7):58. doi:10.3390/molecules24071211
   Web of Science ®Google Scholar
• Paris JL, Baeza A, Vallet-Regí M. Overcoming the stability, toxicity, and biodegradation challenges of tumor stimuli-responsive inorganic nanoparticles for delivery of cancer therapeutics. Expert Opin Drug Deliv. 2019;16(10):1095–1112. doi:10.1080/17425247.2019.1662786
   PubMed Web of Science ®Google Scholar
• Yola ML, Atar N. Amperometric galectin-3 immunosensor-based gold nanoparticle-functionalized graphitic carbon nitride nanosheets and core-shell Ti-MOF@COFs composites. Nanoscale. 2020;12(38):19824–19832. doi:10.1039/d0nr05614f
   PubMed Web of Science ®Google Scholar
• Karimi-Maleh H, Yola ML, Atar N, et al. A novel detection method for organophosphorus insecticide fenamiphos: molecularly imprinted electrochemical sensor based on core-shell Co(3)O(4)@MOF-74 nanocomposite. J Colloid Interface Sci. 2021;592:174–185. doi:10.1016/j.jcis.2021.02.066
   PubMed Web of Science ®Google Scholar
• Yola ML. Sensitive sandwich-type voltammetric immunosensor for breast cancer biomarker HER2 detection based on gold nanoparticles decorated Cu-MOF and Cu(2)ZnSnS(4) NPs/Pt/g-C(3)N(4) composite. Mikrochim Acta. 2021;188(3):78. doi:10.1007/s00604-021-04735-y
   PubMed Web of Science ®Google Scholar
• Yola ML, Atar N. Novel voltammetric tumor necrosis factor-alpha (TNF-α) immunosensor based on gold nanoparticles involved in thiol-functionalized multi-walled carbon nanotubes and bimetallic Ni/Cu-MOFs. Anal Bioanal Chem. 2021;413(9):2481–2492. doi:10.1007/s00216-021-03203-z
   PubMed Web of Science ®Google Scholar
• Lu K, He C, Lin W. Nanoscale metal-organic framework for highly effective photodynamic therapy of resistant head and neck cancer. J Am Chem Soc. 2014;136(48):16712–16715. doi:10.1021/ja508679h
   PubMed Web of Science ®Google Scholar
• Chen R, Zhang J, Wang Y, Chen X, Zapien JA, Lee CS. Graphitic carbon nitride nanosheet@metal-organic framework core-shell nanoparticles for photo-chemo combination therapy. Nanoscale. 2015;7(41):17299–17305. doi:10.1039/c5nr04436g
   PubMed Web of Science ®Google Scholar
• Li SY, Cheng H, Xie BR, et al. Cancer Cell Membrane Camouflaged Cascade Bioreactor for Cancer Targeted Starvation and Photodynamic Therapy. ACS Nano. 2017;11(7):7006–7018. doi:10.1021/acsnano.7b02533
   PubMed Web of Science ®Google Scholar
• Li SY, Cheng H, Qiu WX, et al. Cancer cell membrane-coated biomimetic platform for tumor targeted photodynamic therapy and hypoxia-amplified bioreductive therapy. Biomaterials. 2017;142:149–161. doi:10.1016/j.biomaterials.2017.07.026
   PubMed Web of Science ®Google Scholar
• Liu W, Pan Y, Zhong Y, et al. A multifunctional aminated UiO-67 metal-organic framework for enhancing antitumor cytotoxicity through bimodal drug delivery. Chem Eng, J. 2021;412:127899. doi:10.1016/j.cej.2020.127899
   Web of Science ®Google Scholar
• Lu K, He C, Lin W, Chlorin-Based Nanoscale A. Metal-Organic Framework for Photodynamic Therapy of Colon Cancers. J Am Chem Soc. 2015;137(24):7600–7603. doi:10.1021/jacs.5b04069
   PubMed Web of Science ®Google Scholar
• Lan G, Ni K, Veroneau SS, et al. Titanium-Based Nanoscale Metal-Organic Framework for Type I Photodynamic Therapy. J Am Chem Soc. 2019;141(10):4204–4208. doi:10.1021/jacs.8b13804
   PubMed Web of Science ®Google Scholar
• Luo T, Ni K, Culbert A, et al. Nanoscale Metal-Organic Frameworks Stabilize Bacteriochlorins for Type I and Type II Photodynamic Therapy. J Am Chem Soc. 2020;142(16):7334–7339. doi:10.1021/jacs.0c02129
   PubMed Web of Science ®Google Scholar
• Meng HM, Hu XX, Kong GZ, et al. Aptamer-functionalized nanoscale metal-organic frameworks for targeted photodynamic therapy. Theranostics. 2018;8(16):4332–4344. doi:10.7150/thno.26768
   PubMed Web of Science ®Google Scholar
• Sun Q, Bi H, Wang Z, et al. O2-Generating Metal–Organic Framework-Based Hydrophobic Photosensitizer Delivery System for Enhanced Photodynamic Therapy. ACS Appl Mater Interfaces. 2019;11(40):36347–36358. doi:10.1021/acsami.9b11607
   PubMed Web of Science ®Google Scholar
• Wang D, Wu H, Lim WQ, et al. A Mesoporous Nanoenzyme Derived from Metal-Organic Frameworks with Endogenous Oxygen Generation to Alleviate Tumor Hypoxia for Significantly Enhanced Photodynamic Therapy. Adv Mater. 2019;31(27):e1901893. doi:10.1002/adma.201901893
   PubMed Web of Science ®Google Scholar
• Zheng Q, Liu X, Zheng Y, et al. The recent progress on metal-organic frameworks for phototherapy. Chem Soc Rev. 2021;50(8):5086–5125. doi:10.1039/d1cs00056j
   PubMed Web of Science ®Google Scholar
• Huang X, Sun X, Wang W, et al. Nanoscale metal-organic frameworks for tumor phototherapy. J Mater Chem B. 2021;9(18):3756–3777. doi:10.1039/d1tb00349f
   PubMed Web of Science ®Google Scholar
• Guan Q, Li YA, Li WY, Dong YB. Photodynamic Therapy Based on Nanoscale Metal-Organic Frameworks: from Material Design to Cancer Nanotherapeutics. Chem Asian J. 2018;13(21):3122–3149. doi:10.1002/asia.201801221
   PubMed Web of Science ®Google Scholar
• Suresh K, Matzger AJ. Enhanced Drug Delivery by Dissolution of Amorphous Drug Encapsulated in a Water Unstable Metal-Organic Framework (MOF). Angewandte Chemie. 2019;58(47):16790–16794. doi:10.1002/anie.201907652
   Google Scholar
• Xue S, Zhou X, Sang W, et al. Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy. Bioactive Materials. 2021;6(8):2372–2389. doi:10.1016/j.bioactmat.2021.01.017
   PubMed Web of Science ®Google Scholar
• Liang J, Mazur F, Tang C, Ning X, Chandrawati R, Liang K. Peptide-induced super-assembly of biocatalytic metal-organic frameworks for programmed enzyme cascades. Chem Sci. 2019;10(34):7852–7858. doi:10.1039/c9sc02021g
   PubMed Web of Science ®Google Scholar
• Schnitzer T, Paenurk E, Trapp N, Gershoni-Poranne R, Wennemers H. Peptide-Metal Frameworks with Metal Strings Guided by Dispersion Interactions. J Am Chem Soc. 2021;143(2):644–648. doi:10.1021/jacs.0c11793
   PubMed Web of Science ®Google Scholar
• Liu X, Zhao Y, Li F. Nucleic acid-functionalized metal-organic framework for ultrasensitive immobilization-free photoelectrochemical biosensing. Biosens Bioelectron. 2021;173:112832. doi:10.1016/j.bios.2020.112832
   PubMed Web of Science ®Google Scholar
• Zhuang J, Gong H, Zhou J, et al. Targeted gene silencing in vivo by platelet membrane-coated metal-organic framework nanoparticles. Science Advances. 2020;6(13):eaaz6108. doi:10.1126/sciadv.aaz6108
   PubMed Web of Science ®Google Scholar
• Ni W, Zhang L, Zhang H, Zhang C, Jiang K, Cao X. Hierarchical MOF-on-MOF Architecture for pH/GSH-Controlled Drug Delivery and Fe-Based Chemodynamic Therapy. Inorg Chem. 2022;61(7):3281–3287. doi:10.1021/acs.inorgchem.1c03855
   PubMed Web of Science ®Google Scholar
• Eddaoudi M, Kim J, Rosi N, et al. Systematic design of pore size and functionality in isoreticular MOFs and their application in methane storage. Science. 2002;295(5554):469–472. doi:10.1126/science.1067208
   PubMed Web of Science ®Google Scholar
• Raptopoulou CP. Metal-Organic Frameworks: synthetic Methods and Potential Applications. Materials. 2021;14:2. doi:10.3390/ma14020310
   Web of Science ®Google Scholar
• Qin JH, Zhang H, Sun P, et al. Ionic liquid induced highly dense assembly of porphyrin in MOF nanosheets for photodynamic therapy. Dalton Trans. 2020;49(48):17772–17778. doi:10.1039/d0dt03031g
   PubMed Web of Science ®Google Scholar
• Zhang X, Wasson MC, Shayan M, et al. A historical perspective on porphyrin-based metal-organic frameworks and their applications. Coord Chem Rev. 2021;1:429. doi:10.1016/j.ccr.2020.213615
   Web of Science ®Google Scholar
• Chen J, Zhu Y, Kaskel S. Porphyrin-Based Metal-Organic Frameworks for Biomedical Applications. Angewandte Chemie. 2021;60(10):5010–5035. doi:10.1002/anie.201909880
   Google Scholar
• Liu MD, Yu Y, Guo DK, et al. Integration of a porous coordination network and black phosphorus nanosheets for improved photodynamic therapy of tumor. Nanoscale. 2020;12(16):8890–8897. doi:10.1039/d0nr00956c
   PubMed Web of Science ®Google Scholar
• Ni D, Ferreira CA, Barnhart TE, et al. Magnetic Targeting of Nanotheranostics Enhances Cerenkov Radiation-Induced Photodynamic Therapy. J Am Chem Soc. 2018;140(44):14971–14979. doi:10.1021/jacs.8b09374
   PubMed Web of Science ®Google Scholar
• Zhang D, Ye Z, Wei L, Luo H, Xiao L. Cell Membrane-Coated Porphyrin Metal-Organic Frameworks for Cancer Cell Targeting and O(2)-Evolving Photodynamic Therapy. ACS Appl Mater Interfaces. 2019;11(43):39594–39602. doi:10.1021/acsami.9b14084
   PubMed Web of Science ®Google Scholar
• Liu TF, Feng D, Chen YP, et al. Topology-guided design and syntheses of highly stable mesoporous porphyrinic zirconium metal-organic frameworks with high surface area. J Am Chem Soc. 2015;137(1):413–419. doi:10.1021/ja5111317
   PubMed Web of Science ®Google Scholar
• Park J, Jiang Q, Feng D, Mao L, Zhou HC. Size-Controlled Synthesis of Porphyrinic Metal-Organic Framework and Functionalization for Targeted Photodynamic Therapy. J Am Chem Soc. 2016;138(10):3518–3525. doi:10.1021/jacs.6b00007
   PubMed Web of Science ®Google Scholar
• Liu Y, Zhao Y, Chen X. Bioengineering of Metal-organic Frameworks for Nanomedicine. Theranostics. 2019;9(11):3122–3133. doi:10.7150/thno.31918
   PubMed Web of Science ®Google Scholar
• Jia J, Zhang Y, Zheng M, et al. Functionalized Eu(III)-Based Nanoscale Metal-Organic Framework To Achieve Near-IR-Triggered and -Targeted Two-Photon Absorption Photodynamic Therapy. Inorg Chem. 2018;57(1):300–310. doi:10.1021/acs.inorgchem.7b02475
   PubMed Web of Science ®Google Scholar
• Liu C, Xing J, Akakuru OU, et al. Nanozymes-Engineered Metal-Organic Frameworks for Catalytic Cascades-Enhanced Synergistic Cancer Therapy. Nano Lett. 2019;19(8):5674–5682. doi:10.1021/acs.nanolett.9b02253
   PubMed Web of Science ®Google Scholar
• Pan Y, Luo Z, Wang X, et al. A versatile and multifunctional metal-organic framework nanocomposite toward chemo-photodynamic therapy. Dalton Trans. 2020;49(16):5291–5301. doi:10.1039/c9dt04804a
   PubMed Web of Science ®Google Scholar
• Cai W, Gao H, Chu C, et al. Engineering Phototheranostic Nanoscale Metal-Organic Frameworks for Multimodal Imaging-Guided Cancer Therapy. ACS Appl Mater Interfaces. 2017;9(3):2040–2051. doi:10.1021/acsami.6b11579
   PubMed Web of Science ®Google Scholar
• Gao S, Zheng P, Li Z, et al. Biomimetic O(2)-Evolving metal-organic framework nanoplatform for highly efficient photodynamic therapy against hypoxic tumor. Biomaterials. 2018;178:83–94. doi:10.1016/j.biomaterials.2018.06.007
   PubMed Web of Science ®Google Scholar
• Min H, Wang J, Qi Y, et al. Biomimetic Metal-Organic Framework Nanoparticles for Cooperative Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy. Adv Mater. 2019;31(15):e1808200. doi:10.1002/adma.201808200
   PubMed Web of Science ®Google Scholar
• Illes B, Hirschle P, Barnert S, Cauda V, Wuttke S, Engelke H. Exosome-Coated Metal–Organic Framework Nanoparticles: an Efficient Drug Delivery Platform. Chem Materials. 2017;29(19):8042–8046. doi:10.1021/acs.chemmater.7b02358
   Web of Science ®Google Scholar
• Zhang L, Cheng Q, Li C, Zeng X, Zhang XZ. Near infrared light-triggered metal ion and photodynamic therapy based on AgNPs/porphyrinic MOFs for tumors and pathogens elimination. Biomaterials. 2020;248:120029. doi:10.1016/j.biomaterials.2020.120029
   PubMed Web of Science ®Google Scholar
• Zhou Z, Wang Y, Peng F, et al. Intercalation-Activated Layered MoO(3) Nanobelts as Biodegradable Nanozymes for Tumor-Specific Photo-Enhanced Catalytic Therapy. Angewandte Chemie. 2022:e202115939. doi:10.1002/anie.202115939
   Google Scholar
• Zhang Y, Wang F, Liu C, et al. Nanozyme Decorated Metal-Organic Frameworks for Enhanced Photodynamic Therapy. ACS Nano. 2018;12(1):651–661. doi:10.1021/acsnano.7b07746
   PubMed Web of Science ®Google Scholar
• Richter AM, Kelly B, Chow J, et al. Preliminary studies on a more effective phototoxic agent than hematoporphyrin. J Natl Cancer Inst. 1987;79(6):1327–1332.
   PubMedGoogle Scholar
• Zeng J-Y, Zou M-Z, Zhang M, et al. π-Extended Benzoporphyrin-Based Metal–Organic Framework for Inhibition of Tumor Metastasis. ACS Nano. 2018;12(5):4630–4640. doi:10.1021/acsnano.8b01186
   PubMed Web of Science ®Google Scholar
• Zhang X, Huang X, Xie A, et al. Boosting type I process of Ru(II) compounds by changing tetrazole ligand for enhanced photodynamic therapy against lung cancer. J Inorg Biochem. 2020;212:111236. doi:10.1016/j.jinorgbio.2020.111236
   PubMed Web of Science ®Google Scholar
• Ke Z, Xie A, Chen J, et al. Naturally available hypericin undergoes electron transfer for type I photodynamic and photothermal synergistic therapy. Biomater Sci. 2020;8(9):2481–2487. doi:10.1039/d0bm00021c
   PubMed Web of Science ®Google Scholar
• Li M, Xiong T, Du J, et al. Superoxide Radical Photogenerator with Amplification Effect: surmounting the Achilles’ Heels of Photodynamic Oncotherapy. J Am Chem Soc. 2019;141(6):2695–2702. doi:10.1021/jacs.8b13141
   PubMed Web of Science ®Google Scholar
• Gorman A, Killoran J, O’Shea C, Kenna T, Gallagher WM, O’Shea DF. In vitro demonstration of the heavy-atom effect for photodynamic therapy. J Am Chem Soc. 2004;126(34):10619–10631. doi:10.1021/ja047649e
   PubMed Web of Science ®Google Scholar
• Zhou LL, Guan Q, Li YA, Zhou Y, Xin YB, Dong YB. One-Pot Synthetic Approach toward Porphyrinatozinc and Heavy-Atom Involved Zr-NMOF and Its Application in Photodynamic Therapy. Inorg Chem. 2018;57(6):3169–3176. doi:10.1021/acs.inorgchem.7b03204
   PubMed Web of Science ®Google Scholar
• Zhang K, Yu Z, Meng X, et al. A Bacteriochlorin-Based Metal-Organic Framework Nanosheet Superoxide Radical Generator for Photoacoustic Imaging-Guided Highly Efficient Photodynamic Therapy. Adv Sci. 2019;6(14):1900530. doi:10.1002/advs.201900530
   Web of Science ®Google Scholar
• Kamkaew A, Lim SH, Lee HB, Kiew LV, Chung LY, Burgess K. BODIPY dyes in photodynamic therapy. Chem Soc Rev. 2013;42(1):77–88. doi:10.1039/c2cs35216h
   PubMed Web of Science ®Google Scholar
• Wang W, Wang L, Li Z, Xie Z. BODIPY-containing nanoscale metal-organic frameworks for photodynamic therapy. Chem Commun (Camb). 2016;52(31):5402–5405. doi:10.1039/c6cc01048b
   PubMed Web of Science ®Google Scholar
• Liu CX, Zhang WH, Wang N, et al. Highly Efficient Photocatalytic Degradation of Dyes by a Copper-Triazolate Metal-Organic Framework. Chemistry. 2018;24(63):16804–16813. doi:10.1002/chem.201803306
   PubMed Web of Science ®Google Scholar
• Cai X, Xie Z, Ding B, et al. Monodispersed Copper(I)-Based Nano Metal-Organic Framework as a Biodegradable Drug Carrier with Enhanced Photodynamic Therapy Efficacy. Adv Sci. 2019;6(15):1900848. doi:10.1002/advs.201900848
   Web of Science ®Google Scholar
• Zhao Y, Wang J, Cai X, Ding P, Lv H, Pei R. Metal-Organic Frameworks with Enhanced Photodynamic Therapy: synthesis, Erythrocyte Membrane Camouflage, and Aptamer-Targeted Aggregation. ACS Appl Mater Interfaces. 2020;12(21):23697–23706. doi:10.1021/acsami.0c04363
   PubMed Web of Science ®Google Scholar
• Cai X, Zhao Y, Wang L, et al. Synthesis of Au@MOF core-shell hybrids for enhanced photodynamic/photothermal therapy. J Mater Chem B. 2021;9(33):6646–6657. doi:10.1039/d1tb00800e
   PubMed Web of Science ®Google Scholar
• Luo S, Zhao Y, Pan K, et al. Microneedle-mediated delivery of MIL-100(Fe) as a tumor microenvironment-responsive biodegradable nanoplatform for O(2)-evolving chemophototherapy. Biomater Sci. 2021;9(20):6772–6786. doi:10.1039/d1bm00888a
   PubMed Web of Science ®Google Scholar
• Sun Y, Jiang X, Liu Y, et al. Recent advances in Cu(II)/Cu(I)-MOFs based nano-platforms for developing new nano-medicines. J Inorg Biochem. 2021;225:111599. doi:10.1016/j.jinorgbio.2021.111599
   PubMed Web of Science ®Google Scholar
• Zhang W, Lu J, Gao X, et al. Enhanced Photodynamic Therapy by Reduced Levels of Intracellular Glutathione Obtained By Employing a Nano-MOF with Cu(II) as the Active Center. Angewandte Chemie. 2018;57(18):4891–4896. doi:10.1002/anie.201710800
   Google Scholar
• Wang Y, Wu W, Liu J, et al. Cancer-Cell-Activated Photodynamic Therapy Assisted by Cu(II)-Based Metal-Organic Framework. ACS Nano. 2019;13(6):6879–6890. doi:10.1021/acsnano.9b01665
   PubMed Web of Science ®Google Scholar
• Ni K, Lan G, Song Y, Hao Z, Lin W. Biomimetic nanoscale metal-organic framework harnesses hypoxia for effective cancer radiotherapy and immunotherapy. Chem Sci. 2020;11(29):7641–7653. doi:10.1039/d0sc01949f
   PubMed Web of Science ®Google Scholar
• Lu J, Yang L, Zhang W, et al. Photodynamic therapy for hypoxic solid tumors via Mn-MOF as a photosensitizer. Chem Commun (Camb). 2019;55(72):10792–10795. doi:10.1039/c9cc05107d
   PubMed Web of Science ®Google Scholar
• Meng X, Deng J, Liu F, et al. Triggered All-Active Metal Organic Framework: ferroptosis Machinery Contributes to the Apoptotic Photodynamic Antitumor Therapy. Nano Lett. 2019;19(11):7866–7876. doi:10.1021/acs.nanolett.9b02904
   PubMed Web of Science ®Google Scholar
• Fu X, Yang Z, Deng T, et al. A natural polysaccharide mediated MOF-based Ce6 delivery system with improved biological properties for photodynamic therapy. J Mater Chem B. 2020;8(7):1481–1488. doi:10.1039/c9tb02482d
   PubMed Web of Science ®Google Scholar
• Wang Y, Xu S, Shi L, Teh C, Qi G, Liu B. Cancer-Cell-Activated in situ Synthesis of Mitochondria-Targeting AIE Photosensitizer for Precise Photodynamic Therapy. Angewandte Chemie. 2021;60(27):14945–14953. doi:10.1002/anie.202017350
   Google Scholar
• Kan JL, Jiang Y, Xue A, et al. Surface Decorated Porphyrinic Nanoscale Metal-Organic Framework for Photodynamic Therapy. Inorg Chem. 2018;57(9):5420–5428. doi:10.1021/acs.inorgchem.8b00384
   PubMed Web of Science ®Google Scholar
• Chen R, Chen WC, Yan L, et al. Harnessing combinational phototherapy via post-synthetic PpIX conjugation on nanoscale metal-organic frameworks. J Mater Chem B. 2019;7(31):4763–4770. doi:10.1039/c9tb01154d
   PubMed Web of Science ®Google Scholar
• Guan Q, Zhou LL, Li YA, Dong YB. Diiodo-Bodipy-Encapsulated Nanoscale Metal-Organic Framework for pH-Driven Selective and Mitochondria Targeted Photodynamic Therapy. Inorg Chem. 2018;57(16):10137–10145. doi:10.1021/acs.inorgchem.8b01316
   PubMed Web of Science ®Google Scholar
• Fan W, Huang P, Chen X. Overcoming the Achilles’ heel of photodynamic therapy. Chem Soc Rev. 2016;45(23):6488–6519. doi:10.1039/c6cs00616g
   PubMed Web of Science ®Google Scholar
• Casey SC, Amedei A, Aquilano K, et al. Cancer prevention and therapy through the modulation of the tumor microenvironment. Semin Cancer Biol. 2015;35(Suppl):S199–S223. doi:10.1016/j.semcancer.2015.02.007
   PubMed Web of Science ®Google Scholar
• Wilson WR, Hay MP. Targeting hypoxia in cancer therapy. Nat Rev Cancer. 2011;11(6):393–410. doi:10.1038/nrc3064
   PubMed Web of Science ®Google Scholar
• He L, Ni Q, Mu J, et al. Solvent-Assisted Self-Assembly of a Metal-Organic Framework Based Biocatalyst for Cascade Reaction Driven Photodynamic Therapy. J Am Chem Soc. 2020;142(14):6822–6832. doi:10.1021/jacs.0c02497
   PubMed Web of Science ®Google Scholar
• Liu XL, Dong X, Yang SC, et al. Biomimetic Liposomal Nanoplatinum for Targeted Cancer Chemophototherapy. Adv Sci. 2021;8(8):2003679. doi:10.1002/advs.202003679
   Web of Science ®Google Scholar
• Wang D, Wu H, Yang G, et al. Metal-Organic Framework Derived Multicomponent Nanoagent as a Reactive Oxygen Species Amplifier for Enhanced Photodynamic Therapy. ACS Nano. 2020;14(10):13500–13511. doi:10.1021/acsnano.0c05499
   PubMed Web of Science ®Google Scholar
• Liang R, Liu L, He H, et al. Oxygen-boosted immunogenic photodynamic therapy with gold nanocages@manganese dioxide to inhibit tumor growth and metastases. Biomaterials. 2018;177:149–160. doi:10.1016/j.biomaterials.2018.05.051
   PubMed Web of Science ®Google Scholar
• Liu P, Zhou Y, Shi X, et al. A cyclic nano-reactor achieving enhanced photodynamic tumor therapy by reversing multiple resistances. J Nanobiotechnology. 2021;19(1):149. doi:10.1186/s12951-021-00893-6
   PubMed Web of Science ®Google Scholar
• Ding J, Lu G, Nie W, et al. Self-Activatable Photo-Extracellular Vesicle for Synergistic Trimodal Anticancer Therapy. Adv Mater. 2021;33(7):e2005562. doi:10.1002/adma.202005562
   PubMed Web of Science ®Google Scholar
• Liu W, Wang YM, Li YH, et al. Fluorescent Imaging-Guided Chemotherapy-and-Photodynamic Dual Therapy with Nanoscale Porphyrin Metal-Organic Framework. Small. 2017;13:17. doi:10.1002/smll.201603459
   Web of Science ®Google Scholar
• Luo Z, Tian H, Liu L, et al. Tumor-targeted hybrid protein oxygen carrier to simultaneously enhance hypoxia-dampened chemotherapy and photodynamic therapy at a single dose. Theranostics. 2018;8(13):3584–3596. doi:10.7150/thno.25409
   PubMed Web of Science ®Google Scholar
• Huang X, Chen T, Mu N, et al. Supramolecular micelles as multifunctional theranostic agents for synergistic photodynamic therapy and hypoxia-activated chemotherapy. Acta biomaterialia. 2021;131:483–492. doi:10.1016/j.actbio.2021.07.014
   PubMed Web of Science ®Google Scholar
• Yang G, Tian J, Chen C, et al. An oxygen self-sufficient NIR-responsive nanosystem for enhanced PDT and chemotherapy against hypoxic tumors. Chem Sci. 2019;10(22):5766–5772. doi:10.1039/c9sc00985j
   PubMed Web of Science ®Google Scholar
• Xu X, Chong Y, Liu X, et al. Multifunctional nanotheranostic gold nanocages for photoacoustic imaging guided radio/photodynamic/photothermal synergistic therapy. Acta biomaterialia. 2019;84:328–338. doi:10.1016/j.actbio.2018.11.043
   PubMed Web of Science ®Google Scholar
• Ni K, Lan G, Veroneau SS, Duan X, Song Y, Lin W. Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy. Nat Commun. 2018;9(1):4321. doi:10.1038/s41467-018-06655-7
   PubMed Web of Science ®Google Scholar
• Sun W, Shi T, Luo L, et al. Monodisperse and Uniform Mesoporous Silicate Nanosensitizers Achieve Low-Dose X-Ray-Induced Deep-Penetrating Photodynamic Therapy. Adv Mater. 2019;31(16):e1808024. doi:10.1002/adma.201808024
   PubMed Web of Science ®Google Scholar
• Wang Q, Liu N, Hou Z, Shi J, Su X, Sun X. Radioiodinated Persistent Luminescence Nanoplatform for Radiation-Induced Photodynamic Therapy and Radiotherapy. Adv Healthc Mater. 2021;10(5):e2000802. doi:10.1002/adhm.202000802
   PubMed Web of Science ®Google Scholar
• Zhu Y, Shi H, Li T, et al. A Dual Functional Nanoreactor for Synergistic Starvation and Photodynamic Therapy. ACS Appl Mater Interfaces. 2020;12(16):18309–18318. doi:10.1021/acsami.0c01039
   PubMed Web of Science ®Google Scholar
• Yu Z, Zhou P, Pan W, Li N, Tang B. A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis. Nat Commun. 2018;9(1):5044. doi:10.1038/s41467-018-07197-8
   PubMed Web of Science ®Google Scholar
• Luo Z, Fan X, Chen Y, et al. Mitochondria targeted composite enzyme nanogels for synergistic starvation and photodynamic therapy. Nanoscale. 2021;13(42):17737–17745. doi:10.1039/d1nr06214j
   PubMed Web of Science ®Google Scholar
• Li S, Lin K, Hu P, et al. A multifunctional nanoamplifier with self-enhanced acidity and hypoxia relief for combined photothermal/photodynamic/starvation therapy. Int J Pharm. 2022;611:121307. doi:10.1016/j.ijpharm.2021.121307
   PubMed Web of Science ®Google Scholar
• Wu X, Yang H, Chen X, et al. Nano-herb medicine and PDT induced synergistic immunotherapy for colon cancer treatment. Biomaterials. 2021;269:120654. doi:10.1016/j.biomaterials.2021.120654
   PubMed Web of Science ®Google Scholar
• Huang J, Xiao Z, An Y, et al. Nanodrug with dual-sensitivity to tumor microenvironment for immuno-sonodynamic anti-cancer therapy. Biomaterials. 2021;269:120636. doi:10.1016/j.biomaterials.2020.120636
   PubMed Web of Science ®Google Scholar
• Yang S, Zhang Z, Wang Q. Emerging therapies for small cell lung cancer. J Hematol Oncol. 2019;12(1):47. doi:10.1186/s13045-019-0736-3
   PubMed Web of Science ®Google Scholar
• Chen L, Zhou L, Wang C, et al. Tumor-Targeted Drug and CpG Delivery System for Phototherapy and Docetaxel-Enhanced Immunotherapy with Polarization toward M1-Type Macrophages on Triple Negative Breast Cancers. Adv Mater. 2019;31(52):e1904997. doi:10.1002/adma.201904997
   PubMed Web of Science ®Google Scholar
• Tian J, Xiao C, Huang B, Wang C, Zhang W. Janus macromolecular brushes for synergistic cascade-amplified photodynamic therapy and enhanced chemotherapy. Acta biomaterialia. 2020;101:495–506. doi:10.1016/j.actbio.2019.11.018
   PubMed Web of Science ®Google Scholar
• He C, Duan X, Guo N, et al. Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy. Nat Commun. 2016;7:12499. doi:10.1038/ncomms12499
   PubMed Web of Science ®Google Scholar
• Hu C, Zhuang W, Yu T, et al. Multi-stimuli responsive polymeric prodrug micelles for combined chemotherapy and photodynamic therapy. J Mater Chem B. 2020;8(24):5267–5279. doi:10.1039/d0tb00539h
   PubMed Web of Science ®Google Scholar
• Liu M, Wang L, Zheng X, Liu S, Xie Z. Hypoxia-Triggered Nanoscale Metal-Organic Frameworks for Enhanced Anticancer Activity. ACS Appl Mater Interfaces. 2018;10(29):24638–24647. doi:10.1021/acsami.8b07570
   PubMed Web of Science ®Google Scholar
• De Ruysscher D, Niedermann G, Burnet NG, Siva S, Lee AWM, Hegi-Johnson F. Radiotherapy toxicity. Nature Reviews Disease Primers. 2019;5(1):13. doi:10.1038/s41572-019-0064-5
   PubMed Web of Science ®Google Scholar
• Liu J, Yang Y, Zhu W, et al. Nanoscale metal-organic frameworks for combined photodynamic & radiation therapy in cancer treatment. Biomaterials. 2016;97:1–9. doi:10.1016/j.biomaterials.2016.04.034
   PubMed Web of Science ®Google Scholar
• Yu S, Chen Z, Zeng X, Chen X, Gu Z. Advances in nanomedicine for cancer starvation therapy. Theranostics. 2019;9(26):8026–8047. doi:10.7150/thno.38261
   PubMed Web of Science ®Google Scholar
• He T, Xu H, Zhang Y, et al. Glucose Oxidase-Instructed Traceable Self-Oxygenation/Hyperthermia Dually Enhanced Cancer Starvation Therapy. Theranostics. 2020;10(4):1544–1554. doi:10.7150/thno.40439
   PubMed Web of Science ®Google Scholar
• Wei C, Liu Y, Zhu X, et al. Iridium/ruthenium nanozyme reactors with cascade catalytic ability for synergistic oxidation therapy and starvation therapy in the treatment of breast cancer. Biomaterials. 2020;238:119848. doi:10.1016/j.biomaterials.2020.119848
   PubMed Web of Science ®Google Scholar
• De Miguel M, Calvo E. Clinical Challenges of Immune Checkpoint Inhibitors. Cancer Cell. 2020;38(3):326–333. doi:10.1016/j.ccell.2020.07.004
   PubMed Web of Science ®Google Scholar
• D’Angelo SP, Mahoney MR, Van Tine BA, et al. Nivolumab with or without ipilimumab treatment for metastatic sarcoma (Alliance A091401): two open-label, non-comparative, randomised, Phase 2 trials. Lancet Oncol. 2018;19(3):416–426. doi:10.1016/s1470-2045(18)30006-8
   PubMed Web of Science ®Google Scholar
• Lan G, Ni K, Xu Z, Veroneau SS, Song Y, Lin W. Nanoscale Metal-Organic Framework Overcomes Hypoxia for Photodynamic Therapy Primed Cancer Immunotherapy. J Am Chem Soc. 2018;140(17):5670–5673. doi:10.1021/jacs.8b01072
   PubMed Web of Science ®Google Scholar
• Shao Y, Liu B, Di Z, et al. Engineering of Upconverted Metal-Organic Frameworks for Near-Infrared Light-Triggered Combinational Photodynamic/Chemo-/Immunotherapy against Hypoxic Tumors. J Am Chem Soc. 2020;142(8):3939–3946. doi:10.1021/jacs.9b12788
   PubMed Web of Science ®Google Scholar