Sensitize Tumor Immunotherapy: Immunogenic Cell Death Inducing Nanosystems

References

• Duan X, Chan C, Lin W. Nanoparticle-mediated immunogenic cell death enables and potentiates cancer immunotherapy. Angew. Chem. Int. Ed. 2019;58(3):670–680. doi:10.1002/anie.201804882
   PubMed Web of Science ®Google Scholar
• Couzin-Frankel J. Cancer Immunotherapy. Science. 2013;342(6165):1432–1433. doi:10.1126/science.342.6165.1432
   PubMed Web of Science ®Google Scholar
• Sharma P, Allison JP. The future of immune checkpoint therapy. Science. 2015;348:56–61. doi:10.1126/science.aaa8172
   PubMed Web of Science ®Google Scholar
• Wang DY, Salem JE, Cohen JV, et al. Fatal toxic effects associated with immune checkpoint inhibitors: a systematic review and meta-analysis. JAMA Oncol. 2018;4(12):1721–1728. doi:10.1001/jamaoncol.2018.3923
   PubMed Web of Science ®Google Scholar
• Peng M, Mo Y, Wang Y, et al. Neoantigen vaccine: an emerging tumor immunotherapy. Mol Cancer. 2019;18(1):128. doi:10.1186/s12943-019-1055-6
   PubMed Web of Science ®Google Scholar
• Yatim N, Cullen S, Albert ML. Dying cells actively regulate adaptive immune responses. Nat Rev Immunol. 2017;17(4):262–275. doi:10.1038/nri.2017.9
   PubMed Web of Science ®Google Scholar
• Niu L, Strahotin S, Hewes B, et al. Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in Anti-CD137-treated mice1. J Immunol. 2007;178(7):4194–4213. doi:10.4049/jimmunol.178.7.4194
   PubMed Web of Science ®Google Scholar
• Leonard JP, Sherman ML, Fisher GL, et al. Effects of single-dose interleukin-12 exposure on interleukin-12–associated toxicity and interferon-γ production. Blood. 1997;90(7):2541–2548. doi:10.1182/blood.V90.7.2541
   PubMed Web of Science ®Google Scholar
• Di Giacomo AM, Biagioli M, Maio M. The emerging toxicity profiles of anti–CTLA-4 antibodies across clinical indications. Semin Oncol. 2010;37(5):499–507. doi:10.1053/j.seminoncol.2010.09.007
   PubMed Web of Science ®Google Scholar
• Irvine DJ, Hanson MC, Rakhra K, Tokatlian T. Synthetic nanoparticles for vaccines and immunotherapy. Chem Rev. 2015;115(19):11109–11146. doi:10.1021/acs.chemrev.5b00109
   PubMed Web of Science ®Google Scholar
• Chow EKH, Ho D. Cancer nanomedicine: from drug delivery to imaging. Sci, trans med. 2013;5(216):216rv4–216rv4. doi:10.1126/scitranslmed.3005872
   PubMed Web of Science ®Google Scholar
• Kroemer G, Galassi C, Zitvogel L, Galluzzi L. Immunogenic cell stress and death. Nat Immunol. 2022;23(4):487–500. doi:10.1038/s41590-022-01132-2
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Buqué A, Kepp O, Zitvogel L, Kroemer G. Immunogenic cell death in cancer and infectious disease. Nat Rev Immunol. 2017;17(2):97–111. doi:10.1038/nri.2016.107
   PubMed Web of Science ®Google Scholar
• Jhunjhunwala S, Hammer C, Delamarre L. Antigen presentation in cancer: insights into tumour immunogenicity and immune evasion. Nat Rev Cancer. 2021;21(5):298–312. doi:10.1038/s41568-021-00339-z
   PubMed Web of Science ®Google Scholar
• Dedhar S. Novel functions for calreticulin: interaction with integrins and modulation of gene expression? Trends Biochem Sci. 1994;19(7):269–271. doi:10.1016/0968-0004(94)90001-9
   PubMed Web of Science ®Google Scholar
• Obeid M. ERP57 membrane translocation dictates the immunogenicity of tumor cell death by controlling the membrane translocation of calreticulin1. J Immunol. 2008;181(4):2533–2543. doi:10.4049/jimmunol.181.4.2533
   PubMed Web of Science ®Google Scholar
• Gardai SJ, McPhillips KA, Frasch SC, et al. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell. 2005;123(2):321–334. doi:10.1016/j.cell.2005.08.032
   PubMed Web of Science ®Google Scholar
• Obeid M, Tesniere A, Ghiringhelli F, et al. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med. 2007;13(1):54–61. doi:10.1038/nm1523
   PubMed Web of Science ®Google Scholar
• Panaretakis T, Joza N, Modjtahedi N, et al. The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death. Cell Death Differ. 2008;15(9):1499–1509. doi:10.1038/cdd.2008.67
   PubMed Web of Science ®Google Scholar
• Elliott MR, Chekeni FB, Trampont PC, et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature. 2009;461(7261):282–286. doi:10.1038/nature08296
   PubMed Web of Science ®Google Scholar
• Martins I, Wang Y, Michaud M, et al. Molecular mechanisms of ATP secretion during immunogenic cell death. Cell Death Differ. 2014;21(1):79–91. doi:10.1038/cdd.2013.75
   PubMed Web of Science ®Google Scholar
• Ghiringhelli F, Apetoh L, Tesniere A, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors. Nat Med. 2009;15(10):1170–1178. doi:10.1038/nm.2028
   PubMed Web of Science ®Google Scholar
• Wang Y, Martins I, Ma Y, Kepp O, Galluzzi L, Kroemer G. Autophagy-dependent ATP release from dying cells via lysosomal exocytosis. Autophagy. 2013;9(10):1624–1625. doi:10.4161/auto.25873
   PubMed Web of Science ®Google Scholar
• Michaud M, Martins I, Sukkurwala AQ, et al. Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice. Science. 2011;334(6062):1573–1577. doi:10.1126/science.1208347
   PubMed Web of Science ®Google Scholar
• Li J, Cai W, Yu J, et al. Autophagy inhibition recovers deficient ICD-based cancer immunotherapy. Biomaterials. 2022;287:121651. doi:10.1016/j.biomaterials.2022.121651
   PubMed Web of Science ®Google Scholar
• Yang H, Wang H, Chavan SS, Andersson U. High mobility group box protein 1 (HMGB1): the prototypical endogenous danger molecule. Mol Med. 2015;21(1):S6–S12. doi:10.2119/molmed.2015.00087
   PubMedGoogle Scholar
• Apetoh L, Ghiringhelli F, Tesniere A, et al. Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med. 2007;13(9):1050–1059. doi:10.1038/nm1622
   PubMed Web of Science ®Google Scholar
• Fabian KP, Wolfson B, Hodge JW. From immunogenic cell death to immunogenic modulation: select chemotherapy regimens induce a spectrum of immune-enhancing activities in the tumor microenvironment. Front Oncol. 2021;2021:11.
   Google Scholar
• Fucikova J, Kepp O, Kasikova L, et al. Detection of immunogenic cell death and its relevance for cancer therapy. Cell Death Dis. 2020;11(11):1–13. doi:10.1038/s41419-020-03221-2
   PubMed Web of Science ®Google Scholar
• Kraehenbuehl L, Weng CH, Eghbali S, Wolchok JD, Merghoub T. Enhancing immunotherapy in cancer by targeting emerging immunomodulatory pathways. Nat Rev Clin Oncol. 2022;19(1):37–50. doi:10.1038/s41571-021-00552-7
   PubMed Web of Science ®Google Scholar
• Togashi Y, Shitara K, Nishikawa H. Regulatory T cells in cancer immunosuppression — implications for anticancer therapy. Nat Rev Clin Oncol. 2019;16(6):356–371. doi:10.1038/s41571-019-0175-7
   PubMed Web of Science ®Google Scholar
• Sautès-Fridman C, Petitprez F, Calderaro J, Fridman WH. Tertiary lymphoid structures in the era of cancer immunotherapy. Nat Rev Cancer. 2019;19(6):307–325. doi:10.1038/s41568-019-0144-6
   PubMed Web of Science ®Google Scholar
• Kepp O, Menger L, Vacchelli E, et al. Crosstalk between ER stress and immunogenic cell death. Cytokine Growth Factor Rev. 2013;24(4):311–318. doi:10.1016/j.cytogfr.2013.05.001
   PubMed Web of Science ®Google Scholar
• Garg AD, Dudek-Peric AM, Romano E, Agostinis P. Immunogenic cell death. Int J Dev Biol. 2015;59(1–2–3):131–140. doi:10.1387/ijdb.150061pa
   PubMed Web of Science ®Google Scholar
• Oda N, Shimazu K, Naoi Y, et al. Intratumoral regulatory T cells as an independent predictive factor for pathological complete response to neoadjuvant paclitaxel followed by 5-FU/epirubicin/cyclophosphamide in breast cancer patients. Breast Cancer Res Treat. 2012;136(1):107–116. doi:10.1007/s10549-012-2245-8
   PubMed Web of Science ®Google Scholar
• Panaretakis T, Kepp O, Brockmeier U, et al. Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death. EMBO J. 2009;28(5):578–590. doi:10.1038/emboj.2009.1
   PubMed Web of Science ®Google Scholar
• Liu Z, Xu X, Liu K, Zhang J, Ding D, Fu R. Immunogenic cell death in hematological malignancy therapy. Adv. Sci. 2023;10(13):2207475. doi:10.1002/advs.202207475
   Web of Science ®Google Scholar
• Garg AD, Krysko DV, Verfaillie T, et al. A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J. 2012;31(5):1062–1079. doi:10.1038/emboj.2011.497
   PubMed Web of Science ®Google Scholar
• Yang H, Villani RM, Wang H, et al. The role of cellular reactive oxygen species in cancer chemotherapy. J Exp Clin Cancer Res. 2018;37(1):266. doi:10.1186/s13046-018-0909-x
   PubMed Web of Science ®Google Scholar
• Krysko DV, Garg AD, Kaczmarek A, Krysko O, Agostinis P, Vandenabeele P. Immunogenic cell death and DAMPs in cancer therapy. Nat Rev Cancer. 2012;12(12):860–875. doi:10.1038/nrc3380
   PubMed Web of Science ®Google Scholar
• Rufo N, Garg AD, Agostinis P. The unfolded protein response in immunogenic cell death and cancer immunotherapy. Trends Cancer. 2017;3(9):643–658. doi:10.1016/j.trecan.2017.07.002
   PubMed Web of Science ®Google Scholar
• Dudek AM, Garg AD, Krysko DV, De Ruysscher D, Agostinis P. Inducers of immunogenic cancer cell death. Cytokine Growth Factor Rev. 2013;24(4):319–333. doi:10.1016/j.cytogfr.2013.01.005
   PubMed Web of Science ®Google Scholar
• Schiavoni G, Sistigu A, Valentini M, et al. Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis. Cancer Res. 2011;71(3):768–778. doi:10.1158/0008-5472.CAN-10-2788
   PubMed Web of Science ®Google Scholar
• Bugaut H, Bruchard M, Berger H, et al. Bleomycin exerts ambivalent antitumor immune effect by triggering both immunogenic cell death and proliferation of regulatory T cells. PLoS One. 2013;8(6):e65181. doi:10.1371/journal.pone.0065181
   PubMed Web of Science ®Google Scholar
• Lu Y, Zhu D, Hu B, et al. pH-responsive, self-assembled ruthenium nanodrug: dual impact on lysosomes and DNA for synergistic chemotherapy and immunogenic cell death. Small. 2024:2310636. doi:10.1002/smll.202310636
   Web of Science ®Google Scholar
• Sen S, Hufnagel S, Maier EY, et al. Rationally designed redox-active Au(I) N-heterocyclic carbene: an immunogenic cell death inducer. J Am Chem Soc. 2020;142(49):20536–20541. doi:10.1021/jacs.0c09753
   PubMed Web of Science ®Google Scholar
• Kaur P, Johnson A, Northcote‐Smith J, Lu C, Suntharalingam K. Immunogenic cell death of breast cancer stem cells induced by an endoplasmic reticulum‐targeting copper(II) Complex. ChemBioChem. 2020;21(24):3618–3624. doi:10.1002/cbic.202000553
   PubMed Web of Science ®Google Scholar
• Xiong X, Huang KB, Wang Y, et al. Target profiling of an iridium(III)-based immunogenic cell death inducer unveils the engagement of unfolded protein response regulator BiP. J Am Chem Soc. 2022;144(23):10407–10416. doi:10.1021/jacs.2c02435
   PubMed Web of Science ®Google Scholar
• Terenzi A, Pirker C, Keppler BK, Berger W. Anticancer metal drugs and immunogenic cell death. J Inorg Biochem. 2016;165:71–79. doi:10.1016/j.jinorgbio.2016.06.021
   PubMed Web of Science ®Google Scholar
• Zhang D, Zhang J, Li Q, et al. pH- and Enzyme-Sensitive IR820–paclitaxel conjugate self-assembled nanovehicles for near-infrared fluorescence imaging-guided chemo–photothermal therapy. ACS Appl Mater Interfaces. 2018;10(36):30092–30102. doi:10.1021/acsami.8b09098
   PubMed Web of Science ®Google Scholar
• Lin TJ, Lin HT, Chang WT, et al. Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components. Mol Cancer. 2015;14(1):174. doi:10.1186/s12943-015-0435-9
   PubMedGoogle Scholar
• Yang Y, Li XJ, Chen Z, et al. Wogonin induced calreticulin/Annexin A1 Exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner. PLoS One. 2012;7(12):e50811. doi:10.1371/journal.pone.0050811
   PubMed Web of Science ®Google Scholar
• Lau TS, Chan LKY, Man GCW, et al. Paclitaxel induces immunogenic cell death in ovarian cancer via TLR4/IKK2/SNARE-dependent exocytosis. Cancer Immunol Res. 2020;8(8):1099–1111. doi:10.1158/2326-6066.CIR-19-0616
   PubMed Web of Science ®Google Scholar
• Aranda F, Bloy N, Pesquet J, et al. Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer. Oncogene. 2015;34(23):3053–3062. doi:10.1038/onc.2014.234
   PubMed Web of Science ®Google Scholar
• Bezu L, Sauvat A, Humeau J, et al. eIF2α phosphorylation is pathognomonic for immunogenic cell death. Cell Death Differ. 2018;25(8):1375–1393. doi:10.1038/s41418-017-0044-9
   PubMed Web of Science ®Google Scholar
• Sukkurwala AQ, Adjemian S, Senovilla L, et al. Screening of novel immunogenic cell death inducers within the NCI mechanistic diversity set. OncoImmunology. 2014;3(4):e28473. doi:10.4161/onci.28473
   PubMed Web of Science ®Google Scholar
• Wang H, Mu X, He H, Zhang XD. Cancer Radiosensitizers. Trends Pharmacol Sci. 2018;39(1):24–48. doi:10.1016/j.tips.2017.11.003
   PubMed Web of Science ®Google Scholar
• Seymour CB, Mothersill C. Radiation-induced bystander effects — implications for cancer. Nat Rev Cancer. 2004;4(2):158–164. doi:10.1038/nrc1277
   PubMed Web of Science ®Google Scholar
• Prise KM, O’Sullivan JM. Radiation-induced bystander signalling in cancer therapy. Nat Rev Cancer. 2009;9(5):351–360. doi:10.1038/nrc2603
   PubMed Web of Science ®Google Scholar
• Kim W, Lee S, Seo D, et al. Cellular stress responses in radiotherapy. Cells. 2019;8(9):1105. doi:10.3390/cells8091105
   PubMed Web of Science ®Google Scholar
• Ngiow SF, McArthur GA, Smyth MJ. Radiotherapy complements immune checkpoint blockade. Cancer Cell. 2015;27(4):437–438. doi:10.1016/j.ccell.2015.03.015
   PubMed Web of Science ®Google Scholar
• Deng L, Liang H, Xu M, et al. STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon-dependent antitumor immunity in immunogenic tumors. Immunity. 2014;41(5):843–852. doi:10.1016/j.immuni.2014.10.019
   PubMed Web of Science ®Google Scholar
• Gameiro SR, Jammed ML, Wattenberg MM, Tsang KY, Ferrone S, Hodge JW. Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing. Oncotarget. 2013;5(2):403–416. doi:10.18632/oncotarget.1719
   Google Scholar
• Garnett CT, Palena C, Chakarborty M, Tsang KY, Schlom J, Hodge JW. Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes. Cancer Res. 2004;64(21):7985–7994. doi:10.1158/0008-5472.CAN-04-1525
   PubMed Web of Science ®Google Scholar
• Chakraborty M, Wansley EK, Carrasquillo JA, et al. The use of chelated radionuclide (Samarium-153-Ethylenediaminetetramethylenephosphonate) to modulate phenotype of tumor cells and enhance T cell–mediated killing. Clin Cancer Res. 2008;14(13):4241–4249. doi:10.1158/1078-0432.CCR-08-0335
   PubMed Web of Science ®Google Scholar
• Reits EA, Hodge JW, Herberts CA, et al. Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J Exp Med. 2006;203(5):1259–1271. doi:10.1084/jem.20052494
   PubMed Web of Science ®Google Scholar
• Ahn GO, Tseng D, Liao CH, Dorie MJ, Czechowicz A, Brown JM. Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment. Proc Natl Acad Sci. 2010;107(18):8363–8368. doi:10.1073/pnas.0911378107
   PubMed Web of Science ®Google Scholar
• Kachikwu EL, Iwamoto KS, Liao YP, et al. Radiation enhances regulatory T cell representation. Internat J Rad Oncol Biol Phys. 2011;81(4):1128–1135. doi:10.1016/j.ijrobp.2010.09.034
   PubMed Web of Science ®Google Scholar
• Pan P, Dong X, Chen Y, Ye JJ, Sun YX, Zhang XZ. A heterogenic membrane-based biomimetic hybrid nanoplatform for combining radiotherapy and immunotherapy against breast cancer. Biomaterials. 2022;289:121810. doi:10.1016/j.biomaterials.2022.121810
   PubMed Web of Science ®Google Scholar
• Demaria S, Formenti SC. Radiation as an immunological adjuvant: current evidence on dose and fractionation. Front Oncol. 2012;2:153. doi:10.3389/fonc.2012.00153
   PubMedGoogle Scholar
• Huang Z, Wang Y, Yao D, Wu J, Hu Y, Yuan A. Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress. Nat Commun. 2021;12(1):145. doi:10.1038/s41467-020-20243-8
   PubMed Web of Science ®Google Scholar
• Maggiorella L, Barouch G, Devaux C, et al. Nanoscale radiotherapy with hafnium oxide nanoparticles. Future Oncol. 2012;8(9):1167–1181. doi:10.2217/fon.12.96
   PubMed Web of Science ®Google Scholar
• Ni K, Luo T, Culbert A, Kaufmann M, Jiang X, Lin W. Nanoscale metal–organic framework co-delivers TLR-7 agonists and Anti-CD47 antibodies to modulate macrophages and orchestrate cancer immunotherapy. J Am Chem Soc. 2020;142(29):12579–12584. doi:10.1021/jacs.0c05039
   PubMed Web of Science ®Google Scholar
• Song H, Sun H, He N, et al. Gadolinium-based ultra-small nanoparticles augment radiotherapy-induced T-cell response to synergize with checkpoint blockade immunotherapy. Nanoscale. 2022;14(31):11429–11442. doi:10.1039/D2NR02620A
   PubMed Web of Science ®Google Scholar
• Verry C, Dufort S, Villa J, et al. Theranostic AGuIX nanoparticles as radiosensitizer: a Phase I, dose-escalation study in patients with multiple brain metastases (NANO-RAD trial). Radiother Oncol. 2021;160:159–165. doi:10.1016/j.radonc.2021.04.021
   PubMed Web of Science ®Google Scholar
• Liu Y, Pan Y, Cao W, et al. A tumor microenvironment responsive biodegradable CaCO3/MnO2- based nanoplatform for the enhanced photodynamic therapy and improved PD-L1 immunotherapy. Theranostics. 2019;9(23):6867–6884. doi:10.7150/thno.37586
   PubMed Web of Science ®Google Scholar
• Buytaert E, Dewaele M, Agostinis P. Molecular effectors of multiple cell death pathways initiated by photodynamic therapy. Bioch et Bioph Acta. 2007;1776(1):86–107. doi:10.1016/j.bbcan.2007.07.001
   PubMed Web of Science ®Google Scholar
• Garg AD, Dudek AM, Ferreira GB, et al. ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death. Autophagy. 2013;9(9):1292–1307. doi:10.4161/auto.25399
   PubMed Web of Science ®Google Scholar
• Alzeibak R, Mishchenko TA, Shilyagina NY, Balalaeva IV, Vedunova MV, Krysko DV. Targeting immunogenic cancer cell death by photodynamic therapy: past, present and future. J Immunother Cancer. 2021;9(1):e001926. doi:10.1136/jitc-2020-001926
   PubMed Web of Science ®Google Scholar
• Zeng S, Chen C, Zhang L, et al. Activation of pyroptosis by specific organelle-targeting photodynamic therapy to amplify immunogenic cell death for anti-tumor immunotherapy. Bioact Mater. 2023;25:580–593. doi:10.1016/j.bioactmat.2022.07.016
   PubMed Web of Science ®Google Scholar
• Shao Y, Liu B, Di Z, et al. Engineering of upconverted metal–organic frameworks for near-infrared light-triggered combinational photodynamic/chemo-/immunotherapy against hypoxic tumors. J Am Chem Soc. 2020;142(8):3939–3946. doi:10.1021/jacs.9b12788
   PubMed Web of Science ®Google Scholar
• Vankayala R, Hwang KC. Near-infrared-light-activatable nanomaterial-mediated phototheranostic nanomedicines: an emerging paradigm for cancer treatment. Adv Mater. 2018;30(23):e1706320. doi:10.1002/adma.201706320
   PubMed Web of Science ®Google Scholar
• Xu L, Mou F, Gong H, Luo M, Guan J. Light-driven micro/nanomotors: from fundamentals to applications. Chem Soc Rev. 2017;46(22):6905–6926. doi:10.1039/c7cs00516d
   PubMed Web of Science ®Google Scholar
• Gu Z, Zhu S, Yan L, Zhao F, Zhao Y. Graphene-based smart platforms for combined cancer therapy. Adv. Mater. 2019;31(9):1800662. doi:10.1002/adma.201800662
   PubMed Web of Science ®Google Scholar
• Pan H, Zhang C, Wang T, Chen J, Sun SK. In situ fabrication of intelligent photothermal indocyanine green–alginate hydrogel for localized tumor ablation. ACS Appl Mater Interfaces. 2019;11(3):2782–2789. doi:10.1021/acsami.8b16517
   PubMed Web of Science ®Google Scholar
• Song J, Zhang N, Zhang L, et al. IR780-loaded folate-targeted nanoparticles for near-infrared fluorescence image-guided surgery and photothermal therapy in ovarian cancer. Int j Nanomed. 2019;14:2757–2772. doi:10.2147/IJN.S203108
   PubMed Web of Science ®Google Scholar
• Wu S, Li A, Zhao X, et al. Silica-coated gold–silver nanocages as photothermal antibacterial agents for combined anti-infective therapy. ACS Appl Mater Interfaces. 2019;11(19):17177–17183. doi:10.1021/acsami.9b01149
   PubMed Web of Science ®Google Scholar
• Luo L, Bian Y, Liu Y, et al. Combined near infrared photothermal therapy and chemotherapy using gold nanoshells coated liposomes to enhance antitumor effect. Small. 2016;12(30):4103–4112. doi:10.1002/smll.201503961
   PubMed Web of Science ®Google Scholar
• Lee C, Hwang HS, Lee S, et al. Rabies virus-inspired silica-coated gold nanorods as a photothermal therapeutic platform for treating brain tumors. Adv. Mater. 2017;29(13):1605563. doi:10.1002/adma.201605563
   Web of Science ®Google Scholar
• Guo W, Chen Z, Feng X, et al. Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP). J Nanobiotechnology. 2021;19:146. doi:10.1186/s12951-021-00874-9
   PubMed Web of Science ®Google Scholar
• Zhao Y, Zhao T, Cao Y, et al. Temperature-sensitive lipid-coated carbon nanotubes for synergistic photothermal therapy and gene therapy. ACS Nano. 2021;15(4):6517–6529. doi:10.1021/acsnano.0c08790
   PubMed Web of Science ®Google Scholar
• Maji SK, Yu S, Chung K, et al. Synergistic nanozymetic activity of hybrid gold bipyramid–molybdenum disulfide core@shell nanostructures for two-photon imaging and anticancer therapy. ACS Appl Mater Interfaces. 2018;10(49):42068–42076. doi:10.1021/acsami.8b15443
   PubMed Web of Science ®Google Scholar
• Shin MH, Park EY, Han S, et al. Multimodal cancer theranosis using hyaluronate-conjugated molybdenum disulfide. Adv Healthcare Mater. 2019;8(1):1801036. doi:10.1002/adhm.201801036
   Web of Science ®Google Scholar
• Li N, Sun Q, Yu Z, et al. Nuclear-Targeted photothermal therapy prevents cancer recurrence with near-infrared triggered copper sulfide nanoparticles. ACS Nano. 2018;12(6):5197–5206. doi:10.1021/acsnano.7b06870
   PubMed Web of Science ®Google Scholar
• Ma Y, Zhang Y, Li X, et al. Near-Infrared II phototherapy induces deep tissue immunogenic cell death and potentiates cancer immunotherapy. ACS Nano. 2019;13(10):11967–11980. doi:10.1021/acsnano.9b06040
   PubMed Web of Science ®Google Scholar
• Wang X, Ma Y, Sheng X, Wang Y, Xu H. Ultrathin polypyrrole nanosheets via space-confined synthesis for efficient photothermal therapy in the second near-infrared window. Nano Lett. 2018;18(4):2217–2225. doi:10.1021/acs.nanolett.7b04675
   PubMed Web of Science ®Google Scholar
• Choi V, Rajora MA, Zheng G. Activating drugs with sound: mechanisms behind sonodynamic therapy and the role of nanomedicine. Bioconjugate Chem. 2020;31(4):967–989. doi:10.1021/acs.bioconjchem.0c00029
   PubMed Web of Science ®Google Scholar
• Zhang Y, Khan AR, Yang X, Shi Y, Zhao X, Zhai G. A sonosensitiser‐based polymeric nanoplatform for chemo‐sonodynamic combination therapy of lung cancer. J Nanobiotechnol. 2021;19(1):57. doi:10.1186/s12951-021-00804-9
   PubMed Web of Science ®Google Scholar
• Alphandéry E. Ultrasound and nanomaterial: an efficient pair to fight cancer. J Nanobiotechnology. 2022;20:139. doi:10.1186/s12951-022-01243-w
   PubMed Web of Science ®Google Scholar
• Rengeng L, Qianyu Z, Yuehong L, Zhongzhong P, Libo L. Sonodynamic therapy, a treatment developing from photodynamic therapy. Photodiagnosis Photodyn Ther. 2017;19:159–166. doi:10.1016/j.pdpdt.2017.06.003
   PubMed Web of Science ®Google Scholar
• Yang Y, Huang J, Liu M, et al. Emerging sonodynamic therapy‐based nanomedicines for cancer immunotherapy. Adv Sci. 2022;10(2):2204365. doi:10.1002/advs.202204365
   Web of Science ®Google Scholar
• Gong Z, Dai Z. Design and challenges of sonodynamic therapy system for cancer theranostics: from equipment to sensitizers. Adv. Sci. 2021;8(10):2002178. doi:10.1002/advs.202002178
   Web of Science ®Google Scholar
• Yin Y, Jiang X, Sun L, et al. Continuous inertial cavitation evokes massive ROS for reinforcing sonodynamic therapy and immunogenic cell death against breast carcinoma. Nano Today. 2021;36:101009. doi:10.1016/j.nantod.2020.101009
   Web of Science ®Google Scholar
• Zheng J, Sun J, Chen J, et al. Oxygen and oxaliplatin-loaded nanoparticles combined with photo-sonodynamic inducing enhanced immunogenic cell death in syngeneic mouse models of ovarian cancer. J Control Release. 2021;332:448–459. doi:10.1016/j.jconrel.2021.02.032
   PubMed Web of Science ®Google Scholar
• Ren J, Zhou J, Liu H, et al. Ultrasound (US)-activated redox dyshomeostasis therapy reinforced by immunogenic cell death (ICD) through a mitochondrial targeting liposomal nanosystem. Theranostics. 2021;11(19):9470–9491. doi:10.7150/thno.62984
   PubMed Web of Science ®Google Scholar
• Jiao X, Sun L, Zhang W, et al. Engineering oxygen-deficient ZrO2-x nanoplatform as therapy-activated “immunogenic cell death (ICD)” inducer to synergize photothermal-augmented sonodynamic tumor elimination in NIR-II biological window. Biomaterials. 2021;272:120787. doi:10.1016/j.biomaterials.2021.120787
   PubMed Web of Science ®Google Scholar
• Bai S, Yang N, Wang X, et al. Ultrasmall iron-doped titanium oxide nanodots for enhanced sonodynamic and chemodynamic cancer therapy. ACS Nano. 2020;14(11):15119–15130. doi:10.1021/acsnano.0c05235
   PubMed Web of Science ®Google Scholar
• Fu S, Yang R, Ren J, et al. Catalytically Active CoFe2O4 nanoflowers for augmented sonodynamic and chemodynamic combination therapy with elicitation of robust immune response. ACS Nano. 2021;15(7):11953–11969. doi:10.1021/acsnano.1c03128
   PubMed Web of Science ®Google Scholar
• Wang Q, He Z, Zhang R, et al. Carbon monoxide-based immunogenic cell death amplifier remodels the hypoxic microenvironment for tumor sono-immunotherapy. Chem Eng J. 2024;480:148269. doi:10.1016/j.cej.2023.148269
   Web of Science ®Google Scholar
• Wu M, Yong J, Zhang H, Wang Z, Xu ZP, Zhang R. 2D ultrathin iron doped bismuth oxychloride nanosheets with rich oxygen vacancies for enhanced sonodynamic therapy. Adv Healthcare Mater. 2023;12:2301497. doi:10.1002/adhm.202301497
   Web of Science ®Google Scholar
• Jana D, Zhao Y. Strategies for enhancing cancer chemodynamic therapy performance. Exploration. 2022;2(2):20210238. doi:10.1002/EXP.20210238
   Google Scholar
• Liu XZ, Wen ZJ, Li YM, et al. Bioengineered bacterial membrane vesicles with multifunctional nanoparticles as a versatile platform for cancer immunotherapy. ACS Appl Mater Interfaces. 2023;15(3):3744–3759. doi:10.1021/acsami.2c18244
   PubMed Web of Science ®Google Scholar
• Rahim Pouran S, Abdul Raman AA, Wan Daud WMA. Review on the application of modified iron oxides as heterogeneous catalysts in Fenton reactions. J Cleaner Prod. 2014;64:24–35. doi:10.1016/j.jclepro.2013.09.013
   Web of Science ®Google Scholar
• Hao Y, Li H, Ren F, et al. Ferrocene-conjugated polymeric platform via amide bond formation facilitates enhanced in situ fenton reaction and robust immune responses in combination with toll-like receptor 7/8 agonist. Chem Eng J. 2023;472:144909. doi:10.1016/j.cej.2023.144909
   Web of Science ®Google Scholar
• Wang Y, Ding Y, Yao D, et al. Copper-based nanoscale coordination polymers augmented tumor radioimmunotherapy for immunogenic cell death induction and T-cell infiltration. Small. 2021;17(8):2006231. doi:10.1002/smll.202006231
   Web of Science ®Google Scholar
• Guo W, Chen Z, Li Z, et al. Cancer cell membrane biomimetic mesoporous silica nanotheranostics for enhanced Ferroptosis-mediated immuogenic cell death on Gastric cancer. Chem Eng J. 2023;455:140868. doi:10.1016/j.cej.2022.140868
   Web of Science ®Google Scholar
• Wang Y, Wang D, Zhang Y, et al. Tumor microenvironment-adaptive nanoplatform synergistically enhances cascaded chemodynamic therapy. Bioact Mater. 2022;22:239–253. doi:10.1016/j.bioactmat.2022.09.025
   PubMed Web of Science ®Google Scholar
• Zhang S, Jin L, Liu J, et al. Boosting chemodynamic therapy by the synergistic effect of co-catalyze and photothermal effect triggered by the second near-infrared light. Nano-Micro Lett. 2020;12(1):180. doi:10.1007/s40820-020-00516-z
   PubMed Web of Science ®Google Scholar
• Calderwood SK, Theriault JR, Gong J. How is the immune response affected by hyperthermia and heat shock proteins? Int j Hyperthermia. 2005;21(8):713–716. doi:10.1080/02656730500340794
   PubMed Web of Science ®Google Scholar
• Schueller G, Kettenbach J, Sedivy R, et al. Heat shock protein expression induced by percutaneous radiofrequency ablation of hepatocellular carcinoma in vivo. Int j Oncol. 2004;24(3):609–613. doi:10.3892/ijo.24.3.609
   PubMed Web of Science ®Google Scholar
• Ahmad F, Gravante G, Bhardwaj N, et al. Renal effects of microwave ablation compared with radiofrequency, cryotherapy and surgical resection at different volumes of the liver treated. Liver Int. 2010;30(9):1305–1314. doi:10.1111/j.1478-3231.2010.02290.x
   PubMed Web of Science ®Google Scholar
• van den Bijgaart RJE, Eikelenboom DC, Hoogenboom M, Fütterer JJ, den Brok MH, Adema GJ. Thermal and mechanical high-intensity focused ultrasound: perspectives on tumor ablation, immune effects and combination strategies. Cancer Immunol Immunother. 2017;66(2):247–258. doi:10.1007/s00262-016-1891-9
   PubMed Web of Science ®Google Scholar
• Fietta AM, Morosini M, Passadore I, et al. Systemic inflammatory response and downmodulation of peripheral CD25+Foxp3+ T-regulatory cells in patients undergoing radiofrequency thermal ablation for lung cancer. Hum Immunol. 2009;70(7):477–486. doi:10.1016/j.humimm.2009.03.012
   PubMed Web of Science ®Google Scholar
• Haen SP, Gouttefangeas C, Schmidt D, et al. Elevated serum levels of heat shock protein 70 can be detected after radiofrequency ablation. Cell Stress Chaperones. 2011;16(5):495–504. doi:10.1007/s12192-011-0261-y
   PubMed Web of Science ®Google Scholar
• Faraoni EY, O’Brien BJ, Strickland LN, et al. Radiofrequency ablation remodels the tumor microenvironment and promotes neutrophil-mediated abscopal immunomodulation in pancreatic cancer. Cancer Immunol Res. 2023;11(1):4–12. doi:10.1158/2326-6066.CIR-22-0379
   PubMed Web of Science ®Google Scholar
• Yu M, Pan H, Che N, et al. Microwave ablation of primary breast cancer inhibits metastatic progression in model mice via activation of natural killer cells. Cell Mol Immunol. 2021;18(9):2153–2164. doi:10.1038/s41423-020-0449-0
   PubMed Web of Science ®Google Scholar
• Gioia MD, Spreafico R, Springstead JR, et al. Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation. Nat Immunol. 2020;21(1):42–53. doi:10.1038/s41590-019-0539-2
   PubMed Web of Science ®Google Scholar
• Fite BZ, Wang J, Kare AJ, et al. Immune modulation resulting from MR-guided high intensity focused ultrasound in a model of murine breast cancer. Sci Rep. 2021;11(1):927. doi:10.1038/s41598-020-80135-1
   PubMed Web of Science ®Google Scholar
• Helmstein K. treatment of bladder carcinoma by a hydrostatic pressure technique report on 43 cases. Br J Urol. 1972;44(4):434–450. doi:10.1111/j.1464-410X.1972.tb10103.x
   PubMedGoogle Scholar
• Eisenthal A, Ramakrishna V, Skornick Y, Shinitzky M. Induction of cell-mediated immunity against B16-BL6 melanoma in mice vaccinated with cells modified by hydrostatic pressure and chemical crosslinking. Cancer Immunol Immunother. 1993;36(5):300–306. doi:10.1007/BF01741168
   PubMed Web of Science ®Google Scholar
• Fucikova J, Moserova I, Truxova I, et al. High hydrostatic pressure induces immunogenic cell death in human tumor cells. Internat J Can. 2014;135(5):1165–1177. doi:10.1002/ijc.28766
   PubMed Web of Science ®Google Scholar
• Mikyšková R, Štěpánek I, Indrová M, et al. Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors when combined with docetaxel chemotherapy. Int J Oncol. 2016;48(3):953–964. doi:10.3892/ijo.2015.3314
   PubMed Web of Science ®Google Scholar
• Moehler MH, Zeidler M, Wilsberg V, et al. Parvovirus H-1-induced tumor cell death enhances human immune response in vitro via increased phagocytosis, maturation, and cross-presentation by dendritic cells. Hum Gene Ther. 2005;16(8):996–1005. doi:10.1089/hum.2005.16.996
   PubMed Web of Science ®Google Scholar
• Greiner S, Humrich JY, Thuman P, Sauter B, Schuler G, Jenne L. The highly attenuated vaccinia virus strain modified virus Ankara induces apoptosis in melanoma cells and allows bystander dendritic cells to generate a potent anti-tumoral immunity. Clin Exp Immunol. 2006;146(2):344–353. doi:10.1111/j.1365-2249.2006.03177.x
   PubMed Web of Science ®Google Scholar
• Kelly E, Russell SJ. History of oncolytic viruses: genesis to genetic engineering. Mol Ther. 2007;15(4):651–659. doi:10.1038/sj.mt.6300108
   PubMed Web of Science ®Google Scholar
• Prestwich RJ, Harrington KJ, Pandha HS, Vile RG, Melcher AA, Errington F. Oncolytic viruses: a novel form of immunotherapy. Expert Rev Anticancer Ther. 2008;8(10):1581–1588. doi:10.1586/14737140.8.10.1581
   PubMed Web of Science ®Google Scholar
• Chiocca E, Rabkin S. Oncolytic viruses and their application to cancer immunotherapy. Cancer Immunol Res. 2014;2(4):295–300. doi:10.1158/2326-6066.CIR-14-0015
   PubMed Web of Science ®Google Scholar
• Koks CA, Garg AD, Ehrhardt M, et al. Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death. Internat J Can. 2015;136(5):E313–E325. doi:10.1002/ijc.29202
   PubMed Web of Science ®Google Scholar
• Wang X, Shao X, Gu L, et al. Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells. J Cell & Mol Med. 2020;24(7):4286–4297. doi:10.1111/jcmm.15089
   PubMed Web of Science ®Google Scholar
• Araki H, Tazawa H, Kanaya N, et al. Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer. Molecul Thera. 2022;27:3–13. doi:10.1016/j.omto.2022.09.003
   Web of Science ®Google Scholar
• Donnelly OG, Errington-Mais F, Steele L, et al. Measles virus causes immunogenic cell death in human melanoma. Gene Ther. 2013;20(1):7–15. doi:10.1038/gt.2011.205
   PubMed Web of Science ®Google Scholar
• Miyamoto S, Inoue H, Nakamura T, et al. Coxsackievirus B3 is an oncolytic virus with immunostimulatory properties that is active against lung adenocarcinoma. Cancer Res. 2012;72(10):2609–2621. doi:10.1158/0008-5472.CAN-11-3185
   PubMed Web of Science ®Google Scholar
• Luo JQ, Liu R, Chen FM, et al. Nanoparticle-Mediated CD47-SIRPα blockade and calreticulin exposure for improved cancer chemo-immunotherapy. ACS Nano. 2023;17(10):8966–8979. doi:10.1021/acsnano.2c08240
   PubMed Web of Science ®Google Scholar
• Xue J, Zhu Y, Bai S, et al. Nanoparticles with rough surface improve the therapeutic effect of photothermal immunotherapy against melanoma. Acta Pharm Sin B. 2022;12(6):2934–2949. doi:10.1016/j.apsb.2021.11.020
   PubMed Web of Science ®Google Scholar
• Sethuraman SN, Singh MP, Patil G, et al. Novel calreticulin-nanoparticle in combination with focused ultrasound induces immunogenic cell death in melanoma to enhance antitumor immunity. Theranostics. 2020;10(8):3397–3412. doi:10.7150/thno.42243
   PubMed Web of Science ®Google Scholar
• Yu Z, Guo J, Hu M, Gao Y, Huang L. Icaritin exacerbates mitophagy and synergizes with doxorubicin to induce immunogenic cell death in hepatocellular carcinoma. ACS Nano. 2020;14(4):4816–4828. doi:10.1021/acsnano.0c00708
   PubMed Web of Science ®Google Scholar
• Fu X, Shi Y, Zang H, et al. Combination of oxaliplatin and POM-1 by nanoliposomes to reprogram the tumor immune microenvironment. J Control Release. 2022;347:1–13. doi:10.1016/j.jconrel.2022.04.041
   PubMed Web of Science ®Google Scholar
• Zhang J, Sun X, Zhao X, et al. Combining immune checkpoint blockade with ATP-based immunogenic cell death amplifier for cancer chemo-immunotherapy. Acta Pharm Sin B. 2022;12(9):3694–3709. doi:10.1016/j.apsb.2022.05.008
   PubMed Web of Science ®Google Scholar
• Du Y, Guo Y, Xiao X, et al. Glutathione depletion and photosensitizer activation augments efficacy of tumor photodynamic immunotherapy. Chem Eng J. 2022;442:136170. doi:10.1016/j.cej.2022.136170
   Web of Science ®Google Scholar
• Deng H, Zhou Z, Yang W, et al. Endoplasmic reticulum targeting to amplify immunogenic cell death for cancer immunotherapy. Nano Lett. 2020;20(3):1928–1933. doi:10.1021/acs.nanolett.9b05210
   PubMed Web of Science ®Google Scholar
• Kim CS, Tonga GY, Solfiell D, Rotello VM. Inorganic nanosystems for therapeutic delivery: status and prospects. Adv. Drug Delivery Rev. 2013;65(1):93–99. doi:10.1016/j.addr.2012.08.011
   PubMed Web of Science ®Google Scholar
• Chen Q, Liu L, Lu Y, et al. Tumor microenvironment-triggered aggregated magnetic nanoparticles for reinforced image-guided immunogenic chemotherapy. Adv. Sci. 2019;6(6):1802134. doi:10.1002/advs.201802134
   Web of Science ®Google Scholar
• Zhu L, Li J, Guo Z, Kwok HF, Zhao Q. Synergistic combination of targeted nano-nuclear-reactors and anti-PD-L1 nanobodies evokes persistent T cell immune activation for cancer immunotherapy. J Nanobiotechnology. 2022;20:521. doi:10.1186/s12951-022-01736-8
   PubMed Web of Science ®Google Scholar
• Zhu S, Yan F, Yang L, et al. Low-dose X-ray radiodynamic therapy solely based on gold nanoclusters for efficient treatment of deep hypoxic solid tumors combined with enhanced antitumor immune response. Theranostics. 2023;13(3):1042–1058. doi:10.7150/thno.78649
   PubMed Web of Science ®Google Scholar
• Zhang D, Wu T, Qin X, et al. Intracellularly generated immunological gold nanoparticles for combinatorial photothermal therapy and immunotherapy against tumor. Nano Lett. 2019;19(9):6635–6646. doi:10.1021/acs.nanolett.9b02903
   PubMed Web of Science ®Google Scholar
• Wang C, Xu L, Liang C, Xiang J, Peng R, Liu Z. Immunological responses triggered by photothermal therapy with carbon nanotubes in combination with anti-CTLA-4 therapy to inhibit cancer metastasis. Adv. Mater. 2014;26(48):8154–8162. doi:10.1002/adma.201402996
   PubMed Web of Science ®Google Scholar
• Du X, Yang X, Zhang Y, et al. Transdermal delivery system based on heparin-modified graphene oxide for deep transportation, tumor microenvironment regulation, and immune activation. Nano Today. 2022;46:101565. doi:10.1016/j.nantod.2022.101565
   Web of Science ®Google Scholar
• Zhang F, Chen F, Yang C, et al. Coordination and redox dual-responsive mesoporous organosilica nanoparticles amplify immunogenic cell death for cancer chemoimmunotherapy. Small. 2021;17(26):2100006. doi:10.1002/smll.202100006
   PubMed Web of Science ®Google Scholar
• Li H, Wang M, Huang B, et al. Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis. Nat Commun. 2021;12:7149. doi:10.1038/s41467-021-27485-0
   PubMed Web of Science ®Google Scholar
• Zhao J, Huang H, Zhao J, et al. A hybrid bacterium with tumor-associated macrophage polarization for enhanced photothermal-immunotherapy. Acta Pharmaceutica Sinica B. 2022;12(6):2683–2694. doi:10.1016/j.apsb.2021.10.019
   PubMed Web of Science ®Google Scholar
• Xu J, Xu L, Wang C, et al. Near-Infrared-triggered photodynamic therapy with multitasking upconversion nanoparticles in combination with checkpoint blockade for immunotherapy of colorectal cancer. ACS Nano. 2017;11(5):4463–4474. doi:10.1021/acsnano.7b00715
   PubMed Web of Science ®Google Scholar
• Wang M, Song J, Zhou F, et al. NIR‐triggered phototherapy and immunotherapy via an antigen‐capturing nanoplatform for metastatic cancer treatment. Adv Sci. 2019;6(10):1802157. doi:10.1002/advs.201802157
   Web of Science ®Google Scholar
• Mao D, Hu F, Yi Z, et al. AIEgen-coupled upconversion nanoparticles eradicate solid tumors through dual-mode ROS activation. Sci Adv. 2020;6(26):eabb2712. doi:10.1126/sciadv.abb2712
   PubMed Web of Science ®Google Scholar
• Tian Z, Hu Q, Sun Z, et al. A booster for radiofrequency ablation: advanced adjuvant therapy via in situ nanovaccine synergized with anti-programmed death ligand 1 immunotherapy for systemically constraining hepatocellular carcinoma. ACS Nano. 2023;17(19):19441–19458. doi:10.1021/acsnano.3c08064
   PubMed Web of Science ®Google Scholar
• Li B, Hao G, Sun B, Gu Z, Xu ZP. Engineering a therapy-induced “immunogenic cancer cell death” amplifier to boost systemic tumor elimination. Adv. Funct. Mater. 2020;30(22):1909745. doi:10.1002/adfm.201909745
   Web of Science ®Google Scholar
• Lee N, Yoo D, Ling D, Cho MH, Hyeon T, Cheon J. Iron oxide based nanoparticles for multimodal imaging and magnetoresponsive therapy. Chem Rev. 2015;115(19):10637–10689. doi:10.1021/acs.chemrev.5b00112
   PubMed Web of Science ®Google Scholar
• Chen J, Gong M, Fan Y, et al. Collective plasmon coupling in gold nanoparticle clusters for highly efficient photothermal therapy. ACS Nano. 2022;16(1):910–920. doi:10.1021/acsnano.1c08485
   PubMed Web of Science ®Google Scholar
• Niikura K, Matsunaga T, Suzuki T, et al. Gold nanoparticles as a vaccine platform: influence of size and shape on immunological responses in vitro and in vivo. ACS Nano. 2013;7(5):3926–3938. doi:10.1021/nn3057005
   PubMed Web of Science ®Google Scholar
• Sugikawa K, Kadota T, Yasuhara K, Ikeda A. Anisotropic self-assembly of citrate-coated gold nanoparticles on fluidic liposomes. Angew. Chem. Int. Ed. 2016;55(12):4059–4063. doi:10.1002/anie.201511785
   PubMed Web of Science ®Google Scholar
• Jung HS, Kong WH, Sung DK, et al. Nanographene Oxide–Hyaluronic Acid Conjugate for Photothermal Ablation Therapy of Skin Cancer. ACS Nano. 2014;8(1):260–268. doi:10.1021/nn405383a
   PubMed Web of Science ®Google Scholar
• Meng C, Zhi X, Li C, et al. graphene oxides decorated with carnosine as an adjuvant to modulate innate immune and improve adaptive immunity in vivo. ACS Nano. 2016;10(2):2203–2213. doi:10.1021/acsnano.5b06750
   PubMed Web of Science ®Google Scholar
• Adeli M, Soleyman R, Beiranvand Z, Madani F. Carbon nanotubes in cancer therapy: a more precise look at the role of carbon nanotube–polymer interactions. Chem Soc Rev. 2013;42(12):5231–5256. doi:10.1039/C3CS35431H
   PubMed Web of Science ®Google Scholar
• Fadel TR, Fahmy TM. Immunotherapy applications of carbon nanotubes: from design to safe applications. Trends Biotechnol. 2014;32(4):198–209. doi:10.1016/j.tibtech.2014.02.005
   PubMed Web of Science ®Google Scholar
• Yang M, Meng J, Cheng X, et al. Multiwalled carbon nanotubes interact with macrophages and influence tumor progression and metastasis. Theranostics. 2012;2(3):258–270. doi:10.7150/thno.3629
   PubMed Web of Science ®Google Scholar
• Bao H, Pan Y, Ping Y, et al. Chitosan-functionalized graphene oxide as a nanocarrier for drug and gene delivery. Small. 2011;7(11):1569–1578. doi:10.1002/smll.201100191
   PubMed Web of Science ®Google Scholar
• Feng X, Chen L, Guo W, et al. Graphene oxide induces p62/SQSTM-dependent apoptosis through the impairment of autophagic flux and lysosomal dysfunction in PC12 cells. Acta Biomater. 2018;81:278–292. doi:10.1016/j.actbio.2018.09.057
   PubMed Web of Science ®Google Scholar
• Yan BB, Zhao Y, Li M, et al. Engineering multishelled nanostructures enables stepwise self-degradability for drug-release optimization. Nano Lett. 2022;22(22):9181–9189. doi:10.1021/acs.nanolett.2c04229
   PubMed Web of Science ®Google Scholar
• Badıllı U, Mollarasouli F, Bakirhan NK, Ozkan Y, Ozkan SA. Role of quantum dots in pharmaceutical and biomedical analysis, and its application in drug delivery. TrAC Trends in Analytical Chemistry. 2020;131:116013. doi:10.1016/j.trac.2020.116013
   Web of Science ®Google Scholar
• Zhou Q, Gong N, Zhang D, et al. Mannose-derived carbon dots amplify microwave ablation-induced antitumor immune responses by capturing and transferring “danger signals” to dendritic cells. ACS Nano. 2021;15(2):2920–2932. doi:10.1021/acsnano.0c09120
   PubMed Web of Science ®Google Scholar
• Haase M, Schäfer H. Upconverting Nanoparticles. Angew. Chem. Int. Ed. 2011;50(26):5808–5829. doi:10.1002/anie.201005159
   PubMed Web of Science ®Google Scholar
• Chu H, Zhao J, Mi Y, Di Z, Li L. NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices. Nat Commun. 2019;10:10. doi:10.1038/s41467-019-10847-0
   PubMed Web of Science ®Google Scholar
• Gu Z, Yan L, Tian G, Li S, Chai Z, Zhao Y. Recent advances in design and fabrication of upconversion nanoparticles and their safe theranostic applications. Adv. Mater. 2013;25(28):3758–3779. doi:10.1002/adma.201301197
   PubMed Web of Science ®Google Scholar
• Zhang L, Jin D, Stenzel MH. Polymer-functionalized upconversion nanoparticles for light/imaging-guided drug delivery. Biomacromolecules. 2021;22(8):3168–3201. doi:10.1021/acs.biomac.1c00669
   PubMed Web of Science ®Google Scholar
• Chen C, Song M, Du Y, et al. Tumor-associated-macrophage-membrane-coated nanoparticles for improved photodynamic immunotherapy. Nano Lett. 2021;21(13):5522–5531. doi:10.1021/acs.nanolett.1c00818
   PubMed Web of Science ®Google Scholar
• Li L, Gu W, Chen J, Chen W, Xu ZP. Co-delivery of siRNAs and anti-cancer drugs using layered double hydroxide nanoparticles. Biomaterials. 2014;35(10):3331–3339. doi:10.1016/j.biomaterials.2013.12.095
   PubMed Web of Science ®Google Scholar
• Choy JH, Kwak SY, Jeong YJ, Park JS. Inorganic layered double hydroxides as nonviral vectors. Angew Chem. 2000;112(22):4207–4211. doi:10.1002/1521-3757(20001117)112:22
   Google Scholar
• Samson N, Ablasser A. The cGAS–STING pathway and cancer. Nat Cancer. 2022;3(12):1452–1463. doi:10.1038/s43018-022-00468-w
   PubMedGoogle Scholar
• Wen H, Zhong Y, Yin Y, et al. A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway. Int J Biol Sci. 2022;18(7):2898–2913. doi:10.7150/ijbs.70975
   PubMed Web of Science ®Google Scholar
• Song P, Wang B, Pan Q, et al. GE11-modified carboxymethyl chitosan micelles to deliver DOX·PD-L1 siRNA complex for combination of ICD and immune escape inhibition against tumor. Carbohydr Polym. 2023;312:120837. doi:10.1016/j.carbpol.2023.120837
   PubMed Web of Science ®Google Scholar
• Shi M, Zhang J, Wang Y, et al. Blockage of the IDO1 pathway by charge-switchable nanoparticles amplifies immunogenic cell death for enhanced cancer immunotherapy. Acta Biomater. 2022;150:353–366. doi:10.1016/j.actbio.2022.07.022
   PubMed Web of Science ®Google Scholar
• Liu X, Liu Y, Li X, et al. ER-Targeting PDT converts tumors into in situ therapeutic tumor vaccines. ACS Nano. 2022;16(6):9240–9253. doi:10.1021/acsnano.2c01669
   PubMed Web of Science ®Google Scholar
• Zhou W, Zhou Y, Chen X, et al. Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment. Biomaterials. 2021;268:120546. doi:10.1016/j.biomaterials.2020.120546
   PubMed Web of Science ®Google Scholar
• Cheng H, Fan JH, Zhao LP, et al. Chimeric peptide engineered exosomes for dual-stage light guided plasma membrane and nucleus targeted photodynamic therapy. Biomaterials. 2019;211:14–24. doi:10.1016/j.biomaterials.2019.05.004
   PubMed Web of Science ®Google Scholar
• Wang C, Wang J, Zhang X, et al. In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy. Sci, trans med. 2018;10(429):eaan3682. doi:10.1126/scitranslmed.aan3682
   PubMed Web of Science ®Google Scholar
• Zhang G, Zhan M, Zhang C, et al. Redox-responsive dendrimer nanogels enable ultrasound-enhanced chemoimmunotherapy of pancreatic cancer via endoplasmic reticulum stress amplification and macrophage polarization. Adv. Sci. 2023;10(24):2301759. doi:10.1002/advs.202301759
   Web of Science ®Google Scholar
• Guo Y, Zhang Q, Zhu Q, et al. Copackaging photosensitizer and PD-L1 siRNA in a nucleic acid nanogel for synergistic cancer photoimmunotherapy. Sci Adv. 2022;8(16):eabn2941. doi:10.1126/sciadv.abn2941
   PubMed Web of Science ®Google Scholar
• Sun D, Zou Y, Song L, et al. A cyclodextrin-based nanoformulation achieves co-delivery of ginsenoside Rg3 and quercetin for chemo-immunotherapy in colorectal cancer. Acta Pharm Sin B. 2022;12(1):378–393. doi:10.1016/j.apsb.2021.06.005
   PubMed Web of Science ®Google Scholar
• Sun F, Zhu Q, Li T, et al. Regulating glucose metabolism with prodrug nanoparticles for promoting photoimmunotherapy of pancreatic cancer. Adv Sci. 2021;8(4):2002746. doi:10.1002/advs.202002746
   Web of Science ®Google Scholar
• Hu J, Liang M, Ye M, et al. Reduction-triggered polycyclodextrin supramolecular nanocage induces immunogenic cell death for improved chemotherapy. Carbohydr Polym. 2023;301:120365. doi:10.1016/j.carbpol.2022.120365
   PubMed Web of Science ®Google Scholar
• Han S, Bi S, Guo T, et al. Nano co-delivery of plumbagin and dihydrotanshinone I reverses immunosuppressive TME of liver cancer. J Control Release. 2022;348:250–263. doi:10.1016/j.jconrel.2022.05.057
   PubMed Web of Science ®Google Scholar
• Mahapatro A, Singh DK. Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines. J Nanobiotechnol. 2011;9(1):55. doi:10.1186/1477-3155-9-55
   PubMedGoogle Scholar
• Wang N, Chen M, Wang T. Liposomes used as a vaccine adjuvant-delivery system: from basics to clinical immunization. J Control Release. 2019;303:130–150. doi:10.1016/j.jconrel.2019.04.025
   PubMed Web of Science ®Google Scholar
• Zhao Y, Chen Z, Li Q, et al. Polymer-reinforced liposomes amplify immunogenic cell death-associated antitumor immunity for photodynamic-immunotherapy. Adv. Funct. Mater. 2022;32(52):2209711. doi:10.1002/adfm.202209711
   Web of Science ®Google Scholar
• Guo X, Tu P, Zhu L, et al. Nanoenabled tumor energy metabolism disorder via sonodynamic therapy for multidrug resistance reversal and metastasis inhibition. ACS Appl Mater Interfaces. 2023;15(1):309–326. doi:10.1021/acsami.2c16278
   PubMed Web of Science ®Google Scholar
• Yang Y, Liu X, Ma W, et al. Light-activatable liposomes for repetitive on-demand drug release and immunopotentiation in hypoxic tumor therapy. Biomaterials. 2021;265:120456. doi:10.1016/j.biomaterials.2020.120456
   PubMed Web of Science ®Google Scholar
• Song X, Xu J, Liang C, et al. Self-supplied tumor oxygenation through separated liposomal delivery of H2O2 and catalase for enhanced radio-immunotherapy of cancer. Nano Lett. 2018;18(10):6360–6368. doi:10.1021/acs.nanolett.8b02720
   PubMed Web of Science ®Google Scholar
• Devhare PB, Ray RB. A novel role of exosomes in the vaccination approach. Ann Transl Med. 2017;5(1):23. doi:10.21037/atm.2016.12.75
   PubMed Web of Science ®Google Scholar
• Syn NL, Wang L, Chow EKH, Lim CT, Goh BC. Exosomes in cancer nanomedicine and immunotherapy: prospects and challenges. Trends Biotechnol. 2017;35(7):665–676. doi:10.1016/j.tibtech.2017.03.004
   PubMed Web of Science ®Google Scholar
• Sun D, Zhuang X, Zhang S, et al. Exosomes are endogenous nanoparticles that can deliver biological information between cells. Adv. Drug Delivery Rev. 2013;65(3):342–347. doi:10.1016/j.addr.2012.07.002
   PubMed Web of Science ®Google Scholar
• Lu M, Xing H, Shao W. Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles. Acta Pharmaceutica Sinica B. 2023;13(9):3945–3955. doi:10.1016/j.apsb.2023.03.020
   PubMed Web of Science ®Google Scholar
• Karg M, Pich A, Hellweg T, et al. Nanogels and microgels: from model colloids to applications, recent developments, and future trends. Langmuir. 2019;35(19):6231–6255. doi:10.1021/acs.langmuir.8b04304
   PubMed Web of Science ®Google Scholar
• Ma X, Li SJ, Liu Y, et al. Bioengineered nanogels for cancer immunotherapy. Chem Soc Rev. 2022;51(12):5136–5174. doi:10.1039/D2CS00247G
   PubMed Web of Science ®Google Scholar
• Ma X, Yang S, Zhang T, et al. Bioresponsive immune-booster-based prodrug nanogel for cancer immunotherapy. Acta Pharm Sin B. 2022;12(1):451–466. doi:10.1016/j.apsb.2021.05.016
   PubMed Web of Science ®Google Scholar
• Sahu KM, Patra S, Swain SK. Host-guest drug delivery by β-cyclodextrin assisted polysaccharide vehicles: a review. Int J Biol Macromol. 2023;240:124338. doi:10.1016/j.ijbiomac.2023.124338
   PubMed Web of Science ®Google Scholar
• Hu QD, Tang GP, Chu PK. Cyclodextrin-based host–guest supramolecular nanoparticles for delivery: from design to applications. Acc Chem Res. 2014;47(7):2017–2025. doi:10.1021/ar500055s
   PubMed Web of Science ®Google Scholar
• Pereva S, Sarafska T, Bogdanova S, Т S. Efficiency of “cyclodextrin-ibuprofen” inclusion complex formation. J Drug Delivery Sci Technol. 2016;35:34–39. doi:10.1016/j.jddst.2016.04.006
   Web of Science ®Google Scholar
• Fang RH, CMJ H, Chen KNH, et al. Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles. Nanoscale. 2013;5(19):8884–8888. doi:10.1039/C3NR03064D
   PubMed Web of Science ®Google Scholar
• Aparicio J, Esposito F, Serrano S, et al. Metastatic colorectal cancer. First line therapy for unresectable disease. J Clin Med. 2020;9(12):3889. doi:10.3390/jcm9123889
   PubMed Web of Science ®Google Scholar
• Ni K, Lan G, Lin W. Nanoscale metal–organic frameworks generate reactive oxygen species for cancer therapy. ACS Cent Sci. 2020;6(6):861–868. doi:10.1021/acscentsci.0c00397
   PubMed Web of Science ®Google Scholar
• Gahlawat G, Choudhury AR. A review on the biosynthesis of metal and metal salt nanoparticles by microbes. RSC Adv. 2019;9(23):12944–12967. doi:10.1039/c8ra10483b
   PubMed Web of Science ®Google Scholar
• El-Said WA, Cho HY, Yea CH, Choi JW. Synthesis of metal nanoparticles inside living human cells based on the intracellular formation process. Adv Mater. 2014;26(6):910–918. doi:10.1002/adma.201303699
   PubMed Web of Science ®Google Scholar
• Qin X, Yang C, Xu H, et al. Cell-derived biogenetic gold nanoparticles for sensitizing radiotherapy and boosting immune response against cancer. Small. 2021;17(50):2103984. doi:10.1002/smll.202103984
   Web of Science ®Google Scholar
• Meng X, Zhang F, Guo H, et al. One-Pot Approach to Fe2+ /Fe3+ -Based MOFs with enhanced catalytic activity for fenton reaction. Adv Healthc Mater. 2021;10(19):e2100780. doi:10.1002/adhm.202100780
   PubMed Web of Science ®Google Scholar
• Zanganeh S, Hutter G, Spitler R, et al. Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues. Nat Nanotechnol. 2016;11(11):986–994. doi:10.1038/nnano.2016.168
   PubMed Web of Science ®Google Scholar
• Yang Z, Zhu Y, Dong Z, et al. Tumor-killing nanoreactors fueled by tumor debris can enhance radiofrequency ablation therapy and boost antitumor immune responses. Nat Commun. 2021;12(1):4299. doi:10.1038/s41467-021-24604-9
   PubMed Web of Science ®Google Scholar
• Ma Y, Zhao X, Tian P, et al. Laser-ignited lipid peroxidation nanoamplifiers for strengthening tumor photodynamic therapy through aggravating ferroptotic propagation and sustainable high immunogenicity. Small. 2024;20:2306402. doi:10.1002/smll.202306402
   Web of Science ®Google Scholar
• Jiang M, Chen W, Yu W, et al. Sequentially pH-responsive drug-delivery nanosystem for tumor immunogenic cell death and cooperating with immune checkpoint blockade for efficient cancer chemoimmunotherapy. ACS Appl Mater Interfaces. 2021;13(37):43963–43974. doi:10.1021/acsami.1c10643
   PubMed Web of Science ®Google Scholar
• He J, Song R, Xiao F, Wang M, Wen L. Cu3P/1-MT nanocomposites potentiated photothermal-immunotherapy. Int j Nanomed. 2023;18:3021–3033. doi:10.2147/IJN.S414117
   PubMed Web of Science ®Google Scholar
• Tan J, Ding B, Zheng P, Chen H, Ma P, Lin J. Hollow Aluminum Hydroxide Modified Silica Nanoadjuvants with Amplified Immunotherapy Effects through Immunogenic Cell Death Induction and Antigen Release. Small. 2022;18(34):2202462. doi:10.1002/smll.202202462
   Web of Science ®Google Scholar
• He J, Ouyang X, Xiao F, Liu N, Wen L. Imaging-guided photoacoustic immunotherapy based on the polydopamine-functionalized black phosphorus nanocomposites. ACS Appl Mater Interfaces. 2023;15(47):54322–54334. doi:10.1021/acsami.3c13998
   PubMed Web of Science ®Google Scholar