Ultrasound-Responsive Nanodelivery System of GPC3-Targeting and Sonosensitizer for Visualized Hepatocellular Carcinoma Therapy

References

• Vogel A, Meyer T, Sapisochin G, Salem R, Saborowski A. Hepatocellular carcinoma. Lancet. 2022;400(10360):1345–1362. doi:10.1016/s0140-6736(22)01200-4
   PubMed Web of Science ®Google Scholar
• Sung H, Ferlay J, Siegel RL, et al. global cancer statistics 2020: globocan estimates of incidence and mortality worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–249. doi:10.3322/caac.21660
   PubMed Web of Science ®Google Scholar
• Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023;73(1):17–48. doi:10.3322/caac.21763
   PubMed Web of Science ®Google Scholar
• Maluccio M, Covey A. Recent progress in understanding, diagnosing, and treating hepatocellular carcinoma. CA Cancer J Clin. 2012;62(6):394–399. doi:10.3322/caac.21161
   PubMed Web of Science ®Google Scholar
• Yang JD, Heimbach JK. New advances in the diagnosis and management of hepatocellular carcinoma. BMJ. 371;<pg>m3544. doi:10.1136/bmj.m3544
   Google Scholar
• Forner A, Reig M, Bruix J. Hepatocellular carcinoma. Lancet. 2018;391(10127):1301–1314. doi:10.1016/s0140-6736(18)30010-2
   PubMed Web of Science ®Google Scholar
• Yang B, Chen Y, Shi J. Reactive Oxygen Species (ROS)-Based Nanomedicine. Chem Rev. 2019;119(8):4881–4985. doi:10.1021/acs.chemrev.8b00626
   PubMed Web of Science ®Google Scholar
• Cheung EC, Vousden KH. The role of ROS in tumour development and progression. Nat Rev Cancer. 2022;22(5):280–297. doi:10.1038/s41568-021-00435-0
   PubMed Web of Science ®Google Scholar
• Nakamura H, Takada K. Reactive oxygen species in cancer: current findings and future directions. Can Scie. 2021;112(10):3945–3952. doi:10.1111/cas.15068
   PubMed Web of Science ®Google Scholar
• Liang S, Deng X, Ma P, Cheng Z, Lin J. Recent advances in nanomaterial-assisted combinational sonodynamic cancer therapy. Adv Mater. 2020;32(47):e2003214. doi:10.1002/adma.202003214
   PubMed Web of Science ®Google Scholar
• Beguin E, Shrivastava S, Dezhkunov NV, McHale AP, Callan JF, Stride E. direct evidence of multibubble sonoluminescence using therapeutic ultrasound and microbubbles. ACS Appl Mater Interfac. 2019;11(22):19913–19919. doi:10.1021/acsami.9b07084
   PubMed Web of Science ®Google Scholar
• Gong Z, Dai Z. Design and challenges of sonodynamic therapy system for cancer theranostics: from equipment to sensitizers. Adv Sci. 2021;8(10):2002178. doi:10.1002/advs.202002178
   Web of Science ®Google Scholar
• Huang J, Liu F, Han X, et al. Nanosonosensitizers for highly efficient sonodynamic cancer theranostics. Theranostics. 2018;8(22):6178–6194. doi:10.7150/thno.29569
   PubMed Web of Science ®Google Scholar
• Liao S, Cai M, Zhu R, et al. Antitumor Effect of photodynamic therapy/sonodynamic therapy/sono-photodynamic therapy of chlorin e6 and other applications. Mol Pharm. 20(2):875–885. doi:10.1021/acs.molpharmaceut.2c00824
   PubMedGoogle Scholar
• Jiang Q, Qiao B, Lin X, et al. A hydrogen peroxide economizer for on-demand oxygen production-assisted robust sonodynamic immunotherapy. Theranostics. 2022;12(1):59–75. doi:10.7150/thno.64862
   PubMed Web of Science ®Google Scholar
• Dymek M, Sikora E. Liposomes as biocompatible and smart delivery systems – the current state. Adv. Colloid Interface Sci. 2022;309. doi:10.1016/j.cis.2022.102757
   Web of Science ®Google Scholar
• Meng Z, Zhang Y, Shen E, et al. Marriage of virus‐mimic surface topology and microbubble‐assisted ultrasound for enhanced intratumor accumulation and improved cancer theranostics. Adv Sci. 2021;8(13).
   Web of Science ®Google Scholar
• Mossenta M, Busato D, Dal Bo M, Macor P, Toffoli G. Novel nanotechnology approaches to overcome drug resistance in the treatment of hepatocellular carcinoma: glypican 3 as a useful target for innovative therapies. Int J Mol Sci. 2022;23(17):10038.
   PubMed Web of Science ®Google Scholar
• Li D, Li N, Zhang Y-F, et al. Persistent polyfunctional chimeric antigen receptor T Cells that target glypican 3 eliminate orthotopic hepatocellular carcinomas in mice. Gastroenterology. 2020;158(8):2250–2265.e20. doi:10.1053/j.gastro.2020.02.011
   PubMed Web of Science ®Google Scholar
• Deng H, Shang W, Wang K, et al. Targeted-detection and sequential-treatment of small hepatocellular carcinoma in the complex liver environment by GPC-3-targeted nanoparticles. J Nanobiotechnol. 2022;20(1):156.
   PubMed Web of Science ®Google Scholar
• Feng K, Li X, Huang A, Wan M, Zong Y. Effect of tissue viscoelasticity and adjacent phase-changed microbubbles on vaporization process and direct growth threshold of nanodroplet in an ultrasonic field. Ultrason Sonochem. 2023;101:106665.
   PubMed Web of Science ®Google Scholar
• Namen AV, Jandhyala S, Jordan T, Luke GP. Repeated acoustic vaporization of perfluorohexane nanodroplets for contrast-enhanced ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2021;68(12):3497–3506. doi:10.1109/tuffc.2021.3093828
   PubMed Web of Science ®Google Scholar
• Fan K, Zeng L, Guo J, et al. Visualized podocyte-targeting and focused ultrasound responsive glucocorticoid nano-delivery system against immune-associated nephropathy without glucocorticoid side effect. Theranostics. 2021;11(6):2670–2690. doi:10.7150/thno.53083
   PubMed Web of Science ®Google Scholar
• Gao X, Guo D, Mao X, Shan X, He X, Yu C. Perfluoropentane-filled chitosan poly-acrylic acid nanobubbles with high stability for long-term ultrasound imaging in vivo. Nanoscale. 2021;13(10):5333–5343. doi:10.1039/d0nr06878k
   PubMed Web of Science ®Google Scholar
• Chen K-W, Hsu P-H, Huang H-L, et al. Targeting nanoparticle-conjugated microbubbles combined with ultrasound-mediated microbubble destruction for enhanced tumor therapy. Pharmacol Res. 2022:186. doi:10.1016/j.phrs.2022.106532
   Web of Science ®Google Scholar
• Wang J, Zhang W, Xie Z, et al. Magnetic nanodroplets for enhanced deep penetration of solid tumors and simultaneous magnetothermal‐sensitized immunotherapy against tumor proliferation and metastasis. Adv Healthcare Mater. 2022;11(23). doi:10.1002/adhm.202201399
   Web of Science ®Google Scholar
• Xi L, Han Y, Liu C, et al. Sonodynamic therapy by phase-transition nanodroplets for reducing epidermal hyperplasia in psoriasis. J Control Release. 2022;350:435–447. doi:10.1016/j.jconrel.2022.08.038
   PubMed Web of Science ®Google Scholar
• Li J, Ji H, Jing Y, Wang S. pH- and acoustic-responsive platforms based on perfluoropentane-loaded protein nanoparticles for ovarian tumor-targeted ultrasound imaging and therapy. Nanoscale Res Lett. 15(1):31. doi:10.1186/s11671-020-3252-z
   PubMed Web of Science ®Google Scholar
• Wang G, Jiang Y, Xu J, et al. Unraveling the Plasma Protein Corona by Ultrasonic Cavitation Augments Active-Transporting of Liposome in Solid Tumor. Adv Mater. 2023;35(9):e2207271. doi:10.1002/adma.202207271
   PubMed Web of Science ®Google Scholar
• Yang Y, Zhang JY, Ma ZJ, et al. Visualization of therapeutic intervention for acute liver injury using low-intensity pulsed ultrasound-responsive phase variant nanoparticles. Biomater Sci. 2024. doi:10.1039/d3bm01423a
   Web of Science ®Google Scholar
• Mu W, Jiang D, Mu S, Liang S, Liu Y, Zhang N. Promoting early diagnosis and precise therapy of hepatocellular carcinoma by glypican-3-targeted synergistic chemo-photothermal theranostics. ACS Appl Mater Interfac. 2019;11(26):23591–23604. doi:10.1021/acsami.9b05526
   PubMed Web of Science ®Google Scholar
• Briuglia M-L, Rotella C, McFarlane A, Lamprou DA. Influence of cholesterol on liposome stability and on in vitro drug release. Drug Del Transl Res. 2015;5(3):231–242. doi:10.1007/s13346-015-0220-8
   PubMed Web of Science ®Google Scholar
• Li Y, Zhang X, Cao D. Nanoparticle hardness controls the internalization pathway for drug delivery. Nanoscale. 2015;7(6):2758–2769. doi:10.1039/c4nr05575f
   PubMed Web of Science ®Google Scholar
• Liu Y, Yang S, Zhou Q, et al. Nanobubble-based anti-hepatocellular carcinoma therapy combining immune check inhibitors and sonodynamic therapy. Nanoscale Adv. 4(22):4847–4862. doi:10.1039/d2na00322h
   PubMed Web of Science ®Google Scholar
• Perry JL, Reuter KG, Luft JC, Pecot CV, Zamboni W, DeSimone JM. Mediating Passive Tumor Accumulation through Particle Size, Tumor Type, and Location. Nano lett. 2017;17(5):2879–2886.
   PubMed Web of Science ®Google Scholar
• Pashizeh F, Mansouri A, Bazzazan S, et al. Bioresponsive gingerol-loaded alginate-coated niosomal nanoparticles for targeting intracellular bacteria and cancer cells. Int J Biol Macromol. 2024:258d7. doi:10.1016/j.ijbiomac.2023.128957
   Web of Science ®Google Scholar
• Dastneshan A, Rahiminezhad S, Naderi Mezajin M, et al. Cefazolin encapsulated UIO-66-NH2 nanoparticles enhance the antibacterial activity and biofilm inhibition against drug-resistant S. aureus: in vitro and in vivo studies. Chem Eng J. 2023:455. doi:10.1016/j.cej.2022.140544
   Google Scholar
• Hu S, Xia K, Huang X, et al. Multifunctional CaCO3@Cur@QTX125@HA nanoparticles for effectively inhibiting growth of colorectal cancer cells. J Nanobiotech. 2023;21(1).
   Web of Science ®Google Scholar
• Dwivedi P, Kiran S, Han S, et al. Magnetic Targeting and Ultrasound Activation of Liposome–Microbubble Conjugate for Enhanced Delivery of Anticancer Therapies. ACS Appl Mater Interfac. 2020;12(21):23737–23751. doi:10.1021/acsami.0c05308
   PubMed Web of Science ®Google Scholar
• Chen Y, Luo X, Liu Y, et al. Targeted Nanobubbles of PD-L1 mAb Combined with Doxorubicin as a Synergistic Tumor Repressor in Hepatocarcinoma. Int j Nanomed. 2022;17:3989–4008. doi:10.2147/ijn.S376172
   PubMed Web of Science ®Google Scholar
• Cao Y, Chen Y, Yu T, et al. Drug Release from Phase-Changeable Nanodroplets Triggered by Low-Intensity Focused Ultrasound. Theranostics. 2018;8(5):1327–1339. doi:10.7150/thno.21492
   PubMed Web of Science ®Google Scholar
• Yu L, Wang Z, Mo Z, et al. Synergetic delivery of triptolide and Ce6 with light-activatable liposomes for efficient hepatocellular carcinoma therapy. Acta Pharmaceutica Sinica B. 2021;11(7):2004–2015. doi:10.1016/j.apsb.2021.02.001
   PubMed Web of Science ®Google Scholar
• Żamojć K, Zdrowowicz M, Rudnicki-Velasquez PB, et al. The development of 1,3-diphenylisobenzofuran as a highly selective probe for the detection and quantitative determination of hydrogen peroxide. Free Radic Res. 2016;51(1):38–46. doi:10.1080/10715762.2016.1262541
   PubMed Web of Science ®Google Scholar
• Jin Y, Zhou Q, Geng J, et al. Sonodynamic effects of a novel ether-group modified porphyrin derivative combined with pulsed low-intensity ultrasound on PC-9 Cells. Front Pharmacol. 2021;12. doi:10.3389/fphar.2021.792360
   Web of Science ®Google Scholar
• Lin X, Song J, Chen X, Yang H. Ultrasound‐activated sensitizers and applications. Angew Chem Int Ed. 2020;59(34):14212–14233. doi:10.1002/anie.201906823
   PubMed Web of Science ®Google Scholar
• Kiesslich T, Plaetzer K, Oberdanner CB, Berlanda J, Obermair FJ, Krammer B. Differential effects of glucose deprivation on the cellular sensitivity towards photodynamic treatment‐based production of reactive oxygen species and apoptosis‐induction. FEBS Lett. 2004;579(1):185–190. doi:10.1016/j.febslet.2004.11.073
   Web of Science ®Google Scholar