References
- AlonsoMJNanomedicines for overcoming biological barriersBiomed Pharmacother200458316817215082339
- GrattonSENapierMERoppPATianSDeSimoneJMMicrofabricated particles for engineered drug therapies: elucidation into the mechanisms of cellular internalization of PRINT particlesPharm Res200825122845285218592353
- ParveenSMisraRSahooSKNanoparticles: a boon to drug delivery, therapeutics, diagnostics and imagingNanomedicine20128214716621703993
- BrzoskaMLangerKCoesterCLoitschSWagnerTOMallinckrodtCIncorporation of biodegradable nanoparticles into human airway epithelium cells-in vitro study of the suitability as a vehicle for drug or gene delivery in pulmonary diseasesBiochem Biophys Res Commun2004318256257015120637
- KumariAYadavSKYadavSCBiodegradable polymeric nanoparticles based drug delivery systemsColloids Surf B Biointerfaces201075111819782542
- XiangSTongHShiQUptake mechanisms of non-viral gene deliveryJ Control Release2012158337137821982904
- MousaviSMalerdLBergTKjekenRClathrin-dependent endocytosisBiochem J200437711614505490
- XuSOlenyukBZOkamotoCTHamm-AlvarezSFTargeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advancesAdv Drug Deliv Rev201265112113823026636
- KumariSMgSMayorSEndocytosis unplugged: multiple ways to enter the cellCell Res201020325627520125123
- PelkmansLPüntenerDHeleniusALocal actin polymerization and dynamin recruitment in SV40-induced internalization of caveolaeScience2002296556753553911964480
- WangZTiruppathiCMinshallRDMalikABSize and dynamics of caveolae studied using nanoparticles in living endothelial cellsACS Nano20093124110411619919048
- SahayGAlakhovaDYKabanovAVEndocytosis of nanomedicinesJ Control Release2010145318219520226220
- KerrMCTeasdaleRDDefining macropinocytosisTraffic200910436437119192253
- HillaireauHCouvreurPNanocarriers’ entry into the cell: relevance to drug deliveryCell Mol Life Sci200966172873289619499185
- GrovesEDartACovarelliVCaronEMolecular mechanisms of phagocytic uptake in mammalian cellsCell Mol Life Sci200865131957197618322649
- ParkHCoxDCdc42 regulates Fcγ receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASPMol Biol Cell200920214500450819741094
- BomselMPrydzKPartonRGGruenbergJSimonsKEndocy-tosis in filter-grown Madin-Darby canine kidney cellsJ Cell Biol19891096324332582689455
- Gonzalez-MariscalLHernándezSVegaJInventions designed to enhance drug delivery across epithelial and endothelial cells through the paracellular pathwayRecent Pat Drug Deliv Formul20082214517619075905
- MostovKETransepithelial transport of immunoglobulinsAnnu Rev Immunol199412163848011293
- LuWXiongCZhangRReceptor-mediated transcytosis: a mechanism for active extravascular transport of nanoparticles in solid tumorsJ Control Release2012161395996622617522
- FerratiSMcConnellKIMackACCellular communication via nanoparticle-transporting biovesiclesNanomedicine (Lond)20149558159223731456
- HayashiMTomitaMAwazuSTranscellular and paracellular contribution to transport processes in the colorectal routeAdv Drug Deliv Rev1997282191204
- Salamat-MillerNJohnstonTPCurrent strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epitheliumInt J Pharm2005294120121615814245
- MohanrajVChenYNanoparticles – a reviewTrop J Pharm Res200751561573
- ReddySTBerkDAJainRKSwartzMAA sensitive in vivo model for quantifying interstitial convective transport of injected macromolecules and nanoparticlesJ Appl Physiol (1985)200610141162116916763103
- MoghimiSMHunterACAndresenTLFactors controlling nanoparticle pharmacokinetics: an integrated analysis and perspectiveAnnu Rev Pharmacol Toxicol20125248150322035254
- BaruaSRegeKCancer-cell-phenotype-dependent differential intracellular trafficking of unconjugated quantum dotsSmall20095337037619089841
- SnijderBSacherRRämöPDammEMLiberaliPPelkmansLPopulation context determines cell-to-cell variability in endocytosis and virus infectionNature2009461726352052319710653
- AggarwalPHallJBMcLelandCBDobrovolskaiaMAMcNeilSENanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacyAdv Drug Deliv Rev200961642843719376175
- GunaseelanSGunaseelanKDeshmukhMZhangXSinkoPJSurface modifications of nanocarriers for effective intracellular delivery of anti-HIV drugsAdv Drug Deliv Rev201062451853119941919
- TorranoAABlechingerJOsseforthCA fast analysis method to quantify nanoparticle uptake on a single cell levelNanomedicine (Lond)20138111815182823384698
- LuoYChenDRenLZhaoXQinJSolid lipid nanoparticles for enhancing vinpocetine’s oral bioavailabilityJ Control Release20061141535916828192
- des RieuxAFievezVGarinotMSchneiderYPréatVNanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approachJ Control Release2006116112717050027
- AcostaEBioavailability of nanoparticles in nutrient and nutraceutical deliveryCurr Opin Colloid Interface Sci2009141315
- PatelNRDamannKLeonardiCSabliovCMSize dependency of PLGA-nanoparticle uptake and antifungal activity against Aspergillus flavusNanomedicine (Lond)2011681381139521651442
- ChithraniBDGhazaniAAChanWCDetermining the size and shape dependence of gold nanoparticle uptake into mammalian cellsNano Lett20066466266816608261
- JinHHellerDASharmaRStranoMSSize-dependent cellular uptake and expulsion of single-walled carbon nanotubes: single particle tracking and a generic uptake model for nanoparticlesACS Nano20093114915819206261
- AwaadANakamuraMIshimuraKImaging of size-dependent uptake and identification of novel pathways in mouse Peyer’s patches using fluorescent organosilica particlesNanomedicine20128562763621889475
- RogerELagarceFGarcionEBenoitJLipid nanocarriers improve paclitaxel transport throughout human intestinal epithelial cells by using vesicle-mediated transcytosisJ Control Release2009140217418119699246
- TorchilinVPRecent approaches to intracellular delivery of drugs and DNA and organelle targetingAnnu Rev Biomed Eng2006834337516834560
- NicoleteRDos SantosDFFaccioliLHThe uptake of PLGA micro or nanoparticles by macrophages provokes distinct in vitro inflammatory responseInt Immunopharmacol201111101557156321621649
- LohJWSaundersMLimLYCytotoxicity of monodispersed chitosan nanoparticles against the Caco-2 cellsToxicol Appl Pharmacol2012262327328222609640
- Harush-FrenkelORozenturEBenitaSAltschulerYSurface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cellsBiomacromolecules20089243544318189360
- NanABaiXSonSJLeeSBGhandehariHCellular uptake and cytotoxicity of silica nanotubesNano Lett2008882150215418624386
- IlinaPHyvonenZSauraMSandvigKYliperttulaMRuponenMGenetic block of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systemsJ Control Release2012163338539523041276
- RandRPInteracting phospholipid bilayers: measured forces and induced structural changesAnnu Rev Biophys Bioeng1981102773147020577
- JallouliYPaillardAChangJSevinEBetbederDInfluence of surface charge and inner composition of porous nanoparticles to cross blood–brain barrier in vitroInt J Pharm20073441–210310917651930
- KarlssonJUngellAGråsjöJArturssonPParacellular drug transport across intestinal epithelia: influence of charge and induced water fluxEur J Pharm Sci199991475610493996
- LinICLiangMLiuTYMonteiroMJTothICellular transport pathways of polymer coated gold nanoparticlesNanomedicine20128181122024197
- ZhangLWMonteiro-RiviereNAMechanisms of quantum dot nanoparticle cellular uptakeToxicol Sci2009110113815519414515
- MuthuMSSinghSStudies on biodegradable polymeric nanoparticles of risperidone: in vitro and in vivo evaluationNanomedicine (Lond)20083330531918510426
- ChampionJAKatareYKMitragotriSMaking polymeric micro-and nanoparticles of complex shapesProc Natl Acad Sci U S A200710429119011190417620615
- HaoNLiLZhangQThe shape effect of PEGylated mesoporous silica nanoparticles on cellular uptake pathway in Hela cellsMicroporous Mesoporous Mater20121621423
- HanYAlsayedANobiliMZhangJLubenskyTCYodhAGBrownian motion of an ellipsoidScience2006314579962663017068256
- ChampionJAMitragotriSRole of target geometry in phagocytosisProc Natl Acad Sci U S A2006103134930493416549762
- YangKMaYQComputer simulation of the translocation of nanoparticles with different shapes across a lipid bilayerNat Nanotechnol20105857958320657599
- GrattonSERoppPAPohlhausPDThe effect of particle design on cellular internalization pathwaysProc Natl Acad Sci U S A200810533116131161818697944
- SadeghiBGarmaroudiFSHashemiMComparison of the anti-bacterial activity on the nanosilver shapes: nanoparticles, nanorods and nanoplatesAdv Powder Technol20122312226
- DecuzziPGodinBTanakaTSize and shape effects in the biodistribution of intravascularly injected particlesJ Control Release2010141332032719874859
- ParkJHvon MaltzahnGZhangLSystematic surface engineering of magnetic nanoworms for in vivo tumor targetingSmall20095669470019263431
- DevarajanPVJindalABPatilRRMullaFGaikwadRVSamadAParticle shape: a new design parameter for passive targeting in splenotropic drug deliveryJ Pharm Sci20109962576258120091830
- NaahidiSJafariMEdalatFRaymondKKhademhosseiniAChenPBiocompatibility of engineered nanoparticles for drug deliveryJ Control Release2012166218219423262199
- HowardKAPeerDProviding the full picture: a mandate for standardizing nanoparticle-based drug deliveryNanomedicine (Lond)2013871031103323837825
- DobrovolskaiaMAMcNeilSEImmunological properties of engineered nanomaterialsNat Nanotechnol20772846947818654343
- OwensDE3rdPeppasNAOpsonization, biodistribution, and pharmacokinetics of polymeric nanoparticlesInt J Pharm200630719310216303268
- ChiuYLHoYCChenYMThe characteristics, cellular uptake and intracellular trafficking of nanoparticles made of hydrophobically-modified chitosanJ Control Release2010146115215920580915
- BriggerIDubernetCCouvreurPNanoparticles in cancer therapy and diagnosisAdv Drug Deliv Rev200254563165112204596
- Gomes-da-SilvaLCFernándezYAbasoloIEfficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatformNanomedicine (Lond)2013891397141323394132
- SonajeKLinKJTsengMTEffects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxinsBiomaterials201132338712872121862121
- SambruyYFerruzzaSRanaldiGDe AngelisIIntestinal cell culture models: applications in toxicology and pharmacologyCell Biol Toxicol2001174–530131711768596
- LukBTHuCMFangRHInterfacial interactions between natural RBC membranes and synthetic polymeric nanoparticlesNanoscale2014652730273724463706
- LinTYLiYPZhangHTumor-targeting multifunctional micelles for imaging and chemotherapy of advanced bladder cancerNanomedicine (Lond)2013881239125123199207
- LoureiroJAGomesBCoelhoMACarmo PereiraMDRochaSTargeting nanoparticles across the blood–brain barrier with monoclonal antibodiesNanomedicine (Lond)20149570972224827845
- PatelLNZaroJLShenWCell penetrating peptides: intracellular pathways and pharmaceutical perspectivesPharm Res207724111977199217443399
- JonesATGateways and tools for drug delivery: endocytic pathways and the cellular dynamics of cell penetrating peptidesInt J Pharm20083541–2343818068916
- BarefordLMSwaanPWEndocytic mechanisms for targeted drug deliveryAdv Drug Deliv Rev200759874875817659804
- PujalsSGiraltEProline-rich, amphipathic cell-penetrating peptidesAdv Drug Deliv Rev2008604–547348418187229
- OhPBorgströmPWitkiewiczHLive dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lungNat Biotechnol200725332733717334358
- ObaMAoyagiKMiyataKPolyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular traffickingMol Pharm2008561080109219434856
- LiuJKopeckováPBühlerPBiorecognition and subcellular trafficking of HPMA copolymer-anti-PSMA antibody conjugates by prostate cancer cellsMol Pharm20096395997019344119
- SahooSKMaWLabhasetwarVEfficacy of transferrin-conjugated paclitaxel-loaded nanoparticles in a murine model of prostate cancerInt J Cancer2004112233534015352049
- KocbekPObermajerNCegnarMKosJKristlJTargeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibodyJ Control Release20071201182617509712
- HuangXPengXWangYA reexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals and covalently conjugated peptide ligandsACS Nano20104105887589620863096
- TemsamaniJVidalPThe use of cell-penetrating peptides for drug deliveryDrug Discov Today20049231012101915574317
- PatelPCGiljohannDADanielWLZhengDPrigodichAEMirkinCAScavenger receptors mediate cellular uptake of polyvalent oligonucleotide-functionalized gold nanoparticlesBioconjug Chem201021122250225621070003
- LiuYShiptonMKRyanJSynthesis, stability, and cellular internalization of gold nanoparticles containing mixed peptide-poly(ethylene glycol) monolayersAnal Chem20077962221222917288407
- FortierCDurocherYDe CrescenzoGSurface modification of non-viral nanocarriers for enhanced gene deliveryNanomedicine (Lond)20149113515124354815
- Brannon-PeppasLBlanchetteJONanoparticle and targeted systems for cancer therapyAdv Drug Deliv Rev200456111649165915350294
- VllasaliuDFowlerRGarnettMEatonMStolnikSBarrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparisonBiochem Biophys Res Commun2011415457958522079636
- FerrariMFrontiers in cancer nanomedicine: directing mass transport through biological barriersTrends Biotechnol201028418118820079548
- MasaokaYTanakaYKataokaMSakumaSYamashitaSSite of drug absorption after oral administration: assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tractEur J Pharm Sci2006293–424025016876987
- KuoTRWuCLHsuCTChemical enhancer induced changes in the mechanisms of transdermal delivery of zinc oxide nanoparticlesBiomaterials200930163002300819232716
- Chen-yuGChun-fenYQi-luLDevelopment of a quercetin-loaded nanostructured lipid carrier formulation for topical deliveryInt J Pharm20124301–229229822486962
- BaroliBEnnasMGLoffredoFIsolaMPinnaRLópez-QuintelaMAPenetration of metallic nanoparticles in human full-thickness skinJ Invest Dermatol200712771701171217380118
- ShimJSeok KangHParkWSHanSHKimJChangISTransdermal delivery of mixnoxidil with block copolymer nanoparticlesJ Control Release200497347748415212879
- Ryman-RasmussenJPRiviereJEMonteiro-RiviereNAPenetration of intact skin by quantum dots with diverse physicochemical propertiesToxicol Sci200691115916516443688
- WangJChenJYeNAbsorption, pharmacokinetics and disposition properties of solid lipid nanoparticles (SLNs)Curr Drug Metab201213444745622443539
- TingSRWhitelockJMTomicRCellular uptake and activity of heparin functionalised cerium oxide nanoparticles in monocytesBiomaterials201334174377438623478040
- GuptaHAqilMKharRKAliABhatnagarAMittalGSparfloxacin-loaded PLGA nanoparticles for sustained ocular drug deliveryNanomedicine20106232433319857606
- FreddoTFA contemporary concept of the blood-aqueous barrierProg Retin Eye Res20123218119523128417
- GuinediASMortadaNDMansourSHathoutRMPreparation and evaluation of reverse-phase evaporation and multilamellar niosomes as ophthalmic carriers of acetazolamideInt J Pharm20053061–2718216263229
- de la FuenteMRaviñaMPaolicelliPSanchezASeijoBAlonsoMJChitosan-based nanostructures: a delivery platform for ocular therapeuticsAdv Drug Deliv Rev201062110011719958805
- MautesAEWeinzierlMRDonovanFNobleLJVascular events after spinal cord injury: contribution to secondary pathogenesisPhys Ther200080767368710869130
- DasMPatilSBhargavaNAuto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neuronsBiomaterials200728101918192517222903
- Garcia-GarciaEAndrieuxKGilSA methodology to study intracellular distribution of nanoparticles in brain endothelial cellsInt J Pharm2005298231031415923094
- CostantinoLBoraschiDIs there a clinical future for polymeric nanoparticles as brain-targeting drug delivery agents?Drug Discov Today201217736737822094246
- HynynenKUltrasound for drug and gene delivery to the brainAdv Drug Deliv Rev200860101209121718486271
- StamRElectromagnetic fields and the blood–brain barrierBrain Res Rev2010651809720550949
- ReidDMPerryVHAnderssonPBGordonSMitosis and apoptosis of microglia in vivo induced by an anti-CR3 antibody which crosses the blood–brain barrierNeuroscience19935635295338255420
- KuoYCLeeCLMethylmethacrylate-sulfopropylmethacrylate nanoparticles with surface RMP-7 for targeting delivery of antiretroviral drugs across the blood–brain barrierColloids Surf B Biointerfaces201290758222024400
- DhanikulaRSArgawABouchardJHildgenPMethotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: enhanced efficacy and intratumoral transport capabilityMol Pharm20085110511618171013
- PangZGaoHYuYBrain delivery and cellular internalization mechanisms for transferrin conjugated biodegradable polymersomesInt J Pharm2011415128429221651966
- MartinsSThoIReimoldIBrain delivery of camptothecin by means of solid lipid nanoparticles: formulation design, in vitro and in vivo studiesInt J Pharm20124391–2496223046667
- WenCJYenTCAl-SuwayehSAChangHWFangJYIn vivo real-time fluorescence visualization and brain-targeting mechanisms of lipid nanocarriers with different fatty ester: oil ratiosNanomedicine (Lond)2011691545155922077462
- ThorneRGNicholsonCIn vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular spaceProc Natl Acad Sci U S A2006103145567557216567637
- ZhangXChenGWenLNovel multiple agents loaded PLGA nanoparticles for brain delivery via inner ear administration: in vitro and in vivo evaluationEur J Pharm Sci2013484–559560323354153
- MistryAStolnikSIllumLNanoparticles for direct nose-to-brain delivery of drugsInt J Pharm2009379114615719555750
- GengYDalhaimerPCaiSShape effects of filaments versus spherical particles in flow and drug deliveryNat Nanotechnol20072424925518654271
- JacobsFWisseEDe GeestBThe role of liver sinusoidal cells in hepatocyte-directed gene transferAm J Pathol20101761142119948827
- JohnstonHJSemmler-BehnkeMBrownDMKreylingWTranLStoneVEvaluating the uptake and intracellular fate of polystyrene nanoparticles by primary and hepatocyte cell lines in vitroToxicol Appl Pharmacol20102421667819799923
- LinALiuYHuangYGlycyrrhizin surface-modified chitosan nanoparticles for hepatocyte-targeted deliveryInt J Pharm2008359124725318457928
- KimTHParkIKNahJWChoiYJChoCSGalactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrierBiomaterials200425173783379215020154
- DoshiNMitragotriSMacrophages recognize size and shape of their targetsPLoS One201054e1005120386614
- LaiSKWangYYHanesJMucus-penetrating nanoparticles for drug and gene delivery to mucosal tissuesAdv Drug Deliv Rev200961215817119133304
- MadhavNVShakyaAKShakyaPSinghKOrotransmucosal drug delivery systems: a reviewJ Control Release20091401–221119665039
- TeublBJAbsengerMFröhlichELeitingerGZimmerARobleggEThe oral cavity as a biological barrier system: design of an advanced buccal in vitro permeability modelEur J Pharm Biopharm201384238639323291061
- KochutADerschPBacterial invasion factors: tools for crossing biological barriers and drug delivery?Eur J Pharm Biopharm201384224225023207324
- CocoRPlapiedLPourcelleVDrug delivery to inflamed colon by nanoparticles: comparison of different strategiesInt J Pharm2012440131222820482
- YangMLaiSKWangYYBiodegradable nanoparticles composed entirely of safe materials that rapidly penetrate human mucusAngew Chem Int Ed Engl201150112597260021370345
- O’NeillMJGuoJByrneCDarcyRO’DriscollCMMechanistic studies on the uptake and intracellular trafficking of novel cyclodextrin transfection complexes by intestinal epithelial cellsInt J Pharm20114131–217418321530624
- des RieuxARagnarssonEGGullbergEPréatVSchneiderYJArturssonPTransport of nanoparticles across an in vitro model of the human intestinal follicle associated epitheliumEur J Pharm Sci205525445546515946828
- BrandenbergerCRothen-RutishauserBMühlfeldCEffects and uptake of gold nanoparticles deposited at the air-liquid interface of a human epithelial airway modelToxicol Appl Pharmacol20102421566519796648
- RotoliBMBussolatiOBianchiMGNon-functionalized multi-walled carbon nanotubes alter the paracellular permeability of human airway epithelial cellsToxicol Lett200817829510218403140
- WanakulePLiuGWFleuryATRoyKNano-inside-micro: disease-responsive microgels with encapsulated nanoparticles for intracellular drug delivery to the deep lungJ Control Release2012162242943722841795
- VllasaliuDAlexanderCGarnettMEatonMStolnikSFc-mediated transport of nanoparticles across airway epithelial cell layersJ Control Release2012158347948622200577
- HaraldssonBNyströmJDeenWMProperties of the glomerular barrier and mechanisms of proteinuriaPhysiol Rev200888245148718391170
- HeBJiaZDuWThe transport pathways of polymer nanoparticles in MDCK epithelial cellsBiomaterials201334174309432623478037
- ChristensenEIVerroustPJNielsenRReceptor-mediated endocytosis in renal proximal tubulePflugers Arch200945861039104819499243
- BertrandNLerouxJCThe journey of a drug-carrier in the body: an anatomo-physiological perspectiveJ Control Release2012161215216322001607
- KodairaHTsutsumiYYoshiokaYThe targeting of anionized polyvinylpyrrolidone to the renal systemBiomaterials200425184309431515046921
- YamamotoYTsutsumiYYoshiokaYPoly(vinylpyrrolidone-co-dimethyl maleic acid) as a novel renal targeting carrierJ Control Release200495222923714980771
- YuanZXZhangZRZhuDSpecific renal uptake of randomly 50% N-acetylated low molecular weight chitosanMol Pharm20086130531419035784
- NarayananKYenSKDouQMimicking cellular transport mechanism in stem cells through endosomal escape of new peptide-coated quantum dotsSci Rep20133218423851637
- TkachenkoAGXieHColemanDMultifunctional gold nanoparticle-peptide complexes for nuclear targetingJ Am Chem Soc2003125164700470112696875
- ChenJWuCOupickýDBioreducible hyperbranched poly(amido amine)s for gene deliveryBiomacromolecules200910102921292719743843