Nanomedicine strategies for treatment of secondary spinal cord injury

References

• BurkeDLindenRZhangYMaisteAShieldsCIncidence rates and populations at risk for spinal cord injury: a regional studySpinal Cord20013927427811438844
   PubMed Web of Science ®Google Scholar
• HallEDBraughlerJMCentral nervous system trauma and stroke: II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidationFree Radic Biol Med198963033132663663
   PubMed Web of Science ®Google Scholar
• HamannKShiRAcrolein scavenging: a potential novel mechanism of attenuating oxidative stress following spinal cord injuryJ Neurochem20091111348135619780896
   PubMed Web of Science ®Google Scholar
• HaglundESeale-GoldsmithM-MLearyJFDesign of multifunctional nanomedical systemsAnn Biomed Eng2009372048206319169822
   PubMed Web of Science ®Google Scholar
• Seale-GoldsmithM-MLearyJFNanobiosystemsWiley Interdiscip Rev Nanomed Nanobiotechnol2009155356720049817
   PubMedGoogle Scholar
• LearyJFNanotechnology: what is it and why is small so big?Can J Ophthalmol20104544945620856270
   PubMedGoogle Scholar
• LearyJFNanomedicine – reality will trump hype!J Nanomedicine Biotherapeutic Discov201341e125
   Google Scholar
• AvgoustakisKBeletsiAPanagiZKlepetsanisPKarydasAIthakissiosDPLGA-mPEG nanoparticles of cisplatin: in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood propertiesJ Control Release20027912313511853924
   PubMed Web of Science ®Google Scholar
• NiidomeTYamagataMOkamotoYPEG-modified gold nanorods with a stealth character for in vivo applicationsJ Control Release200611434334716876898
   PubMed Web of Science ®Google Scholar
• SashiwaHYajimaHAibaSSynthesis of a chitosan-dendrimer hybrid and its biodegradationBiomacromolecules200341244124912959590
   PubMed Web of Science ®Google Scholar
• ZhangCWänglerBMorgensternBSilica- and alkoxysilane-coated ultrasmall superparamagnetic iron oxide particles: a promising tool to label cells for magnetic resonance imagingLangmuir2006231427143417241069
   PubMedGoogle Scholar
• CaffertyWBDuffyPHuebnerEStrittmatterSMMAG and OMgp synergize with Nogo-A to restrict axonal growth and neurological recovery after spinal cord traumaJ Neurosci2010306825683720484625
   PubMed Web of Science ®Google Scholar
• GrandPreTNakamuraFVartanianTStrittmatterSMIdentification of the Nogo inhibitor of axon regeneration as a Reticulon proteinNature200040343944410667797
   PubMed Web of Science ®Google Scholar
• KottisVThibaultPMikolDOligodendrocyte-myelin glycoprotein (OMgp) is an inhibitor of neurite outgrowthJ Neurochem2002821566156912354307
   PubMed Web of Science ®Google Scholar
• MukhopadhyayGDohertyPWalshFSCrockerPRFilbinMTA novel role for myelin-associated glycoprotein as an inhibitor of axonal regenerationNeuron1994137577677522484
   PubMed Web of Science ®Google Scholar
• WinzelerAMMandemakersWJSunMZStaffordMPhillipsCTBarresBAThe lipid sulfatide is a novel myelin-associated inhibitor of CNS axon outgrowthJ Neurosci2011316481649221525289
   PubMed Web of Science ®Google Scholar
• IdeCTohyamaKYokotaRNitatoriTOnoderaSSchwann cell basal lamina and nerve regenerationBrain Res198328861756661636
   PubMed Web of Science ®Google Scholar
• SonY-JThompsonWJSchwann cell processes guide regeneration of peripheral axonsNeuron1995141251327826630
   PubMed Web of Science ®Google Scholar
• XuXMChenAGuenardVKleitmanNBungeMBBridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cordJ Neurocytol1997261169154524
   PubMedGoogle Scholar
• SimonCMSharifSTanRPLaPlacaMCSpinal cord contusion causes acute plasma membrane damageJ Neurotrauma20092656357419260780
   PubMedGoogle Scholar
• HallJGuytonAOrganization of the nervous system, basic functions of synapses, and neurotransmittersGuyton and Hall Textbook of Medical Physiology12th edPhiladelphia, PA, USASaunders/Elsevier2011
   Google Scholar
• BhatMARiosJCLuYAxon-glia interactions and the domain organization of myelinated axons requires neurexin IV/Caspr/ParanodinNeuron20013036938311395000
   PubMed Web of Science ®Google Scholar
• SasakiMMolecular reconstruction of nodes of Ranvier after remyelination by transplanted olfactory ensheathing cells in the demyelinated spinal cordJ Neurosci2006261803181216467529
   PubMed Web of Science ®Google Scholar
• OlssonTWhite matter disease: roles of anti-MOG antibodies in demyelinating diseasesNat Rev Neurol2011724824921537356
   PubMedGoogle Scholar
• WallströmEKhademiMAnderssonMWeissertRLiningtonCOlssonTIncreased reactivity to myelin oligodendrocyte glycoprotein peptides and epitope mapping in HLA DR2(15)+ multiple sclerosisEur J Immunol199828332933359808202
   PubMed Web of Science ®Google Scholar
• MetzJKellyASwettVCWaxmanSHerbertVDeranged DNA synthesis by bone marrow from vitamin B12-deficient humansBr J Haematol1968145755925657159
   PubMed Web of Science ®Google Scholar
• RadomskiMWPalmerRMMoncadaSThe anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxideBr J Pharmacol1987926396463322462
   PubMed Web of Science ®Google Scholar
• ThorneKJSvvennsenRJFranksDRole of hydrogen peroxide in the cytotoxic reaction of T lymphocytesClin Exp Immunol1980394864956248285
   PubMedGoogle Scholar
• WhiteAACrawfordKMPattCSLadPJActivation of soluble guanylate cyclase from rat lung by incubation or by hydrogen peroxideJ Biol Chem19762517304731212160
   PubMed Web of Science ®Google Scholar
• WollowitzSHalpernJFree radical rearrangement involving the 1,2-migration of a thioester group. Model for the coenzyme B12-dependent methylmalonyl-CoA mutase reactionJ Am Chem Soc198410683198321
   Google Scholar
• ScottGSCuzzocreaSGenoveseTKoprowskiHHooperDCUric acid protects against secondary damage after spinal cord injuryProc Natl Acad Sci U S A20051023483348815728348
   PubMed Web of Science ®Google Scholar
• HamannKDurkesAOuyangHUchidaKPondAShiRCritical role of acrolein in secondary injury following ex vivo spinal cord traumaJ Neurochem200810771272118710419
   PubMedGoogle Scholar
• Lopez-ValesRRedensekASkinnerTAAFenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in miceJ Neurosci2010303220322620203181
   PubMedGoogle Scholar
• MarkowitzAJWhiteMGKolsonDLJordan-SciuttoKLCellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegenerationCellscience2007411114619122795
   PubMedGoogle Scholar
• ZhengLTOckJKwonB-MSukKSuppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicityInt Immunopharmacol2008848449418279803
   PubMed Web of Science ®Google Scholar
• HamannKNehrtGOuyangHDuerstockBShiRHydralazine inhibits compression and acrolein-mediated injuries in ex vivo spinal cordJ Neurochem200810470871817995940
   PubMed Web of Science ®Google Scholar
• LuoJUchidaKShiRAccumulation of acrolein-protein adducts after traumatic spinal cord injuryNeurochem Res20053029129516018572
   PubMedGoogle Scholar
• Liu-SnyderPMcNallyHShiRBorgensRBAcrolein-mediated mechanisms of neuronal deathJ Neurosci Res20068420921816619238
   PubMed Web of Science ®Google Scholar
• LuoJShiRAcrolein induces axolemmal disruption, oxidative stress, and mitochondrial impairment in spinal cord tissueNeurochem Int20044447548615209416
   PubMed Web of Science ®Google Scholar
• ShiRLuoJPeasleyMAcrolein inflicts axonal membrane disruption and conduction loss in isolated guinea-pig spinal cordNeuroscience200211533734012421600
   PubMed Web of Science ®Google Scholar
• UchidaKKanematsuMMorimitsuYOsawaTNoguchiNNikiEAcrolein is a product of lipid peroxidation reactionJ Biol Chem199827316058160669632657
   PubMed Web of Science ®Google Scholar
• AyerHEYeagerDWIrritants in cigarette smoke plumesAm J Public Health198272128312857125032
   PubMed Web of Science ®Google Scholar
• MottramDSWedzichaBLDodsonATFood chemistry: acrylamide is formed in the Maillard reactionNature200241944844912368844
   PubMed Web of Science ®Google Scholar
• TsaiC-JChenM-LChangK-FChangF-KMaoI-FThe pollution characteristics of odor, volatile organochlorinated compounds and polycyclic aromatic hydrocarbons emitted from plastic waste recycling plantsChemosphere2009741104111019091382
   PubMed Web of Science ®Google Scholar
• Liu-SnyderPLoganMPShiRSmithDTBorgensRBNeuroprotection from secondary injury by polyethylene glycol requires its internalizationJ Exp Biol20072101455146217401128
   PubMed Web of Science ®Google Scholar
• ZittingAHeinonenTDecrease of reduced glutathione in isolated rat hepatocytes caused by acrolein, acrylonitrile, and the thermal degradation products of styrene copolymersToxicology1980173333417210018
   PubMed Web of Science ®Google Scholar
• SilvermanRBThe Organic Chemistry of Enzyme-Catalyzed ReactionsSan Diego, CA, USAAcademic Press2002
   Google Scholar
• BettsRWeinsheimerSBlouseGEAnagliJStructural determinants of the calpain inhibitory activity of calpastatin peptide B27-WTJ Biol Chem20032787800780912500971
   PubMed Web of Science ®Google Scholar
• TompaPBuzder-LantosPTantosAOn the sequential determinants of calpain cleavageJ Biol Chem2004279207752078514988399
   PubMed Web of Science ®Google Scholar
• CrockerSJSmithPDJackson-LewisVInhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson’s diseaseJ Neurosci2003234081409112764095
   PubMed Web of Science ®Google Scholar
• RaySKFidanMNowakMWWilfordGGHoganELBanikNLOxidative stress and Ca2+ influx upregulate calpain and induce apoptosis in PC12 cellsBrain Res200085232633410678759
   PubMedGoogle Scholar
• RaySKMatzelleDDWilfordGGHoganELBanikNLIncreased calpain expression is associated with apoptosis in rat spinal cord injury: calpain inhibitor provides neuroprotectionNeurochem Res2000251191119811059793
   PubMedGoogle Scholar
• ShieldsDCTyorWRDeiblerGEHoganELBanikNLIncreased calpain expression in activated glial and inflammatory cells in experimental allergic encephalomyelitisProc Natl Acad Sci U S A199895576857729576959
   PubMedGoogle Scholar
• SquierMKSehnertAJSellinsKSMalkinsonAMTakanoECohenJJCalpain and calpastatin regulate neutrophil apoptosisJ Cell Physiol19991783113199989777
   PubMed Web of Science ®Google Scholar
• TrincheseFFa’MLiuSInhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer diseaseJ Clin Invest20081182796280718596919
   PubMed Web of Science ®Google Scholar
• AvernaMDe TullioRCapiniPSalaminoFPontremoliSMelloniEChanges in calpastatin localization and expression during calpain activation: a new mechanism for the regulation of intracellular Ca2+-dependent proteolysisCell Mol Life Sci2003602669267814685690
   PubMedGoogle Scholar
• MurachiTTanakaKHatanakaMMurakamiTIntracellular Ca2+-dependent protease (CALPAIN) and its high-molecular-weight endogenous inhibitor (CALPASTATIN)Adv Enzyme Regul1981194074246278869
   PubMedGoogle Scholar
• SasakiTKishiMSaitoMInhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsinsJ Enzyme Inhib Med Chem19903195201
   Google Scholar
• TsujinakaTKajiwaraYKambayashiJSynthesis of a new cell penetrating calpain inhibitor (calpeptin)Biochem Biophys Res Commun1988153120112082839170
   PubMed Web of Science ®Google Scholar
• WangKKNathRPosnerAAn alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotectiveProc Natl Acad Sci U S A199693668766928692879
   PubMed Web of Science ®Google Scholar
• WuH-YTomizawaKMatsushitaMLuY-FLiS-TMatsuiHPolyarginine-fused calpastatin peptide, a living cell membrane-permeable and specific inhibitor for calpainNeurosci Res20034713113512941454
   PubMed Web of Science ®Google Scholar
• DonkorIOCalpain inhibitors: a survey of compounds reported in the patent and scientific literatureExpert Opin Ther Pat20112160163621434837
   PubMed Web of Science ®Google Scholar
• MakiMBagciHHamaguchiKUedaMMurachiTHatanakaMInhibition of calpain by a synthetic oligopeptide corresponding to an exon of the human calpastatin geneJ Biol Chem198926418866188692553724
   PubMed Web of Science ®Google Scholar
• HannaRACampbellRLDaviesPLCalcium-bound structure of calpain and its mechanism of inhibition by calpastatinNature200845640941219020623
   PubMed Web of Science ®Google Scholar
• JiaoWMcDonaldDQCoxonJMParkerEJMolecular modeling studies of peptide inhibitors highlight the importance of conformational prearrangement for inhibition of calpainBiochemistry2010495533553920499928
   PubMed Web of Science ®Google Scholar
• HugenholtzHCassDEDvorakMFHigh-dose methylprednisolone for acute closed spinal cord injury – only a treatment optionCan J Neurol Sci20022922723512195611
   PubMed Web of Science ®Google Scholar
• BrackenMBShepardMJCollinsWFA randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injuryN Engl J Med1990322140514112278545
   PubMed Web of Science ®Google Scholar
• WitschiAReddySStoferBLauterburgBThe systemic availability of oral glutathioneEur J Clin Pharmacol1992436676691362956
   PubMed Web of Science ®Google Scholar
• AebiSAsseretoRLauterburgBHHigh-dose intravenous glutathione in man. Pharmacokinetics and effects on cyst(e)ine in plasma and urineEur J Clin Invest1991211031101907548
   PubMedGoogle Scholar
• TateishiNHigashiTNaruseANakashimaKShiozakiHRat liver glutathione: possible role as a reservoir of cysteineJ Nutr1977107516013167
   PubMed Web of Science ®Google Scholar
• DasASribnickEAWingraveJMCalpain activation in apoptosis of ventral spinal cord 4.1 (VSC4.1) motoneurons exposed to glutamate: calpain inhibition provides functional neuroprotectionJ Neurosci Res20058155156215968645
   PubMedGoogle Scholar
• GuytonMKDasASamantaraySCalpeptin attenuated inflammation, cell death, and axonal damage in animal model of multiple sclerosisJ Neurosci Res2010882398240820623621
   PubMedGoogle Scholar
• RaySKWilfordGGMatzelleDCHoganELBanikNLCalpeptin and methylprednisolone inhibit apoptosis in rat spinal cord injuryAnn N Y Acad Sci199989026126910668431
   PubMedGoogle Scholar
• YuC-GGeddesJSustained calpain inhibition improves locomotor function and tissue sparing following contusive spinal cord injuryNeurochem Res2007322046205317476592
   PubMedGoogle Scholar
• Liu-SnyderPBorgensRBShiRHydralazine rescues PC12 cells from acrolein-mediated deathJ Neurosci Res20068421922716619236
   PubMed Web of Science ®Google Scholar
• ChoYShiRBorgensRBIvanisevicAFunctionalized mesoporous silica nanoparticle-based drug delivery system to rescue acrolein-mediated cell deathNanomedicine (Lond)2008350751918694313
   PubMed Web of Science ®Google Scholar
• LeungGSunWZhengLBrookesSTullyMShiRAnti-acrolein treatment improves behavioral outcome and alleviates myelin damage in experimental autoimmune encephalomyelitis mouseNeuroscience201117315015521081153
   PubMed Web of Science ®Google Scholar
• LeitchIMReadMABouraALWaltersWAEffect of inhibition of nitric oxide synthase and guanylate cyclase on hydralazine-induced vasodilatation of the human fetal placental circulationClin Exp Pharmacol Physiol1994216156227529152
   PubMedGoogle Scholar
• ShenDDHoslerJPSchroderRLAzarnoffDLPharmacokinetics of hydralazine and its acid-labile hydrazone metabolites in relation to acetylator phenotypeJ Pharmacokinet Pharmacodyn198085368
   Google Scholar
• ChoYShiRBorgensRBChitosan produces potent neuroprotection and physiological recovery following traumatic spinal cord injuryJ Exp Biol20102131513152020400636
   PubMed Web of Science ®Google Scholar
• ShahidiFSynowieckiJIsolation and characterization of nutrients and value-added products from snow crab (Chionoecetes opilio) and shrimp (Pandalus borealis) processing discardsJ Agric Food Chem19913915271532
   Web of Science ®Google Scholar
• KolhePKannanRMImprovement in ductility of chitosan through blending and copolymerization with PEG: FTIR investigation of molecular interactionsBiomacromolecules2002417318012523863
   PubMedGoogle Scholar
• MaoSShuaiXUngerFWittmarMXieXKisselTSynthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymersBiomaterials2005266343635615913769
   PubMed Web of Science ®Google Scholar
• ZhangMLiXHGongYDZhaoNMZhangXFProperties and biocompatibility of chitosan films modified by blending with PEGBiomaterials2002232641264812059013
   PubMed Web of Science ®Google Scholar
• De CamposAMSánchezAGrefRCalvoPAlonsoMJThe effect of a PEG versus a chitosan coating on the interaction of drug colloidal carriers with the ocular mucosaEur J Pharm Sci200320738113678795
   PubMed Web of Science ®Google Scholar
• AbbottWABridgesRJMeisterAExtracellular metabolism of glu-tathione accounts for its disappearance from the basolateral circulation of the kidneyJ Biol Chem198425915393154006150935
   PubMed Web of Science ®Google Scholar
• BarthJWinklerJSchumannRPopulation pharmacokinetics of methylprednisolone in accident victims with spinal cord injuryInt J Clin Pharmacol Ther20044250451115487809
   PubMedGoogle Scholar
• SmythHFCarpenterCPWeilCSThe chronic oral toxicology of the polyethylene glycolsJ Am Pharm Assoc1955442730
   Google Scholar
• ChoYShiRBorgensRBChitosan nanoparticle-based neuronal membrane sealing and neuroprotection following acrolein-induced cell injuryJ Biol Eng20104220205817
   PubMedGoogle Scholar
• OnishiHMachidaYBiodegradation and distribution of water-soluble chitosan in miceBiomaterials19992017518210022787
   PubMed Web of Science ®Google Scholar
• BaeYHParkKTargeted drug delivery to tumors: myths, reality and possibilityJ Control Release201115319820521663778
   PubMed Web of Science ®Google Scholar
• FarokhzadOCChengJTeplyBATargeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivoProc Natl Acad Sci U S A20061036315632016606824
   PubMed Web of Science ®Google Scholar
• KeyJDhawanDKnappDWMultimodal in vivo MRI and NIRF imaging of bladder tumor using peptide conjugated glycol chitosan nanoparticlesProc SPIE2012822582251F82251F
   Google Scholar
• Kukowska-LatalloJFCandidoKACaoZNanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancerCancer Res2005655317532415958579
   PubMed Web of Science ®Google Scholar
• SchiffelersRMAnsariAXuJCancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticleNucleic Acids Res200432e14915520458
   PubMed Web of Science ®Google Scholar
• YuD-HLuQXieJFangCChenH-ZPeptide-conjugated biodegradable nanoparticles as a carrier to target paclitaxel to tumor neovasculatureBiomaterials2010312278229220053444
   PubMed Web of Science ®Google Scholar
• HeQZhangZGaoFLiYShiJIn vivo biodistribution and urinary excretion of mesoporous silica nanoparticles: effects of particle size and PEGylationSmall2011727128021213393
   PubMed Web of Science ®Google Scholar
• HuangXLiLLiuTThe shape effect of mesoporous silica nanoparticles on biodistribution, clearance, and biocompatibility in vivoACS Nano201155390539921634407
   PubMed Web of Science ®Google Scholar
• CorbalanJJMedinaCJacobyAMalinskiTRadomskiMWAmorphous silica nanoparticles trigger nitric oxide/peroxynitrite imbalance in human endothelial cells: inflammatory and cytotoxic effectsInt J Nanomedicine201162821283522131828
   PubMed Web of Science ®Google Scholar
• NapierskaDThomassenLCRabolliVSize-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cellsSmall2009584685319288475
   PubMed Web of Science ®Google Scholar
• NooneyRIThirunavukkarasuDChenYJosephsROstafinAESynthesis of nanoscale mesoporous silica spheres with controlled particle sizeChem Mater20021447214728
   Web of Science ®Google Scholar
• StöberWFinkABohnEControlled growth of monodisperse silica spheres in the micron size rangeJ Colloid Interface Sci1968266269
   Web of Science ®Google Scholar
• ConnorEEMwamukaJGoleAMurphyCJWyattMDGold nanoparticles are taken up by human cells but do not cause acute cytotoxicitySmall2005132532717193451
   PubMed Web of Science ®Google Scholar
• ElghanianRStorhoffJJMucicRCLetsingerRLMirkinCASelective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticlesScience1997277107810819262471
   PubMed Web of Science ®Google Scholar
• El-SayedIHHuangXEl-SayedMASurface plasmon resonance scattering and absorption of anti-EGFR antibody conjugated gold nanoparticles in cancer diagnostics: applications in oral cancerNano Lett2005582983415884879
   PubMed Web of Science ®Google Scholar
• GoodmanCMMcCuskerCDYilmazTRotelloVMToxicity of gold nanoparticles functionalized with cationic and anionic side chainsBioconjug Chem20041589790015264879
   PubMed Web of Science ®Google Scholar
• StorhoffJJElghanianRMucicRCMirkinCALetsingerRLOne-pot colorimetric differentiation of polynucleotides with single base imperfections using gold nanoparticle probesJ Am Chem Soc199812019591964
   Web of Science ®Google Scholar
• BallouBLagerholmBCErnstLABruchezMPWaggonerASNoninvasive imaging of quantum dots in miceBioconjug Chem200315798614733586
   PubMedGoogle Scholar
• GaoXCuiYLevensonRMChungLWNieSIn vivo cancer targeting and imaging with semiconductor quantum dotsNat Biotechnol20042296997615258594
   PubMed Web of Science ®Google Scholar
• HauckTSAndersonREFischerHCNewbiggingSChanWCIn vivo quantum-dot toxicity assessmentSmall2010613814419743433
   PubMed Web of Science ®Google Scholar
• HoshinoAFujiokaKOkuTPhysicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modificationNano Lett2004421632169
   Web of Science ®Google Scholar
• LovrićJBazziHSCuieYFortinGRWinnikFMMaysingerDDifferences in subcellular distribution and toxicity of green and red emitting CdTe quantum dotsJ Mol Med20058337738515688234
   PubMed Web of Science ®Google Scholar
• YuWWChangEDrezekRColvinVLWater-soluble quantum dots for biomedical applicationsBiochem Biophys Res Commun200634878178616904647
   PubMed Web of Science ®Google Scholar
• Hyung ParkJKwonSLeeMSelf-assembled nanoparticles based on glycol chitosan bearing hydrophobic moieties as carriers for doxorubicin: in vivo biodistribution and anti-tumor activityBiomaterials20062711912616023198
   PubMed Web of Science ®Google Scholar
• MinKHParkKKimY-SHydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapyJ Control Release200812720821818336946
   PubMed Web of Science ®Google Scholar
• XuPGullottiETongLIntracellular drug delivery by poly(lactic-co-glycolic acid) nanoparticles, revisitedMol Pharm2008619020119035785
   PubMedGoogle Scholar
• KuSYanFWangYSunYYangNYeLThe blood–brain barrier penetration and distribution of PEGylated fluorescein-doped magnetic silica nanoparticles in rat brainBiochem Biophys Res Commun201039487187620206605
   PubMed Web of Science ®Google Scholar
• LuYYinYMayersBTXiaYModifying the surface properties of superparamagnetic iron oxide nanoparticles through a sol-gel approachNano Lett20022183186
   Web of Science ®Google Scholar
• SantraSTapecRTheodoropoulouNDobsonJHebardATanWSynthesis and characterization of silica-coated iron oxide nanoparticles in microemulsion: the effect of nonionic surfactantsLangmuir20011729002906
   Web of Science ®Google Scholar
• YuCHAl-SaadiAShihS-JQiuLTamKYTsangSCImmobilization of BSA on silica-coated magnetic iron oxide nanoparticleJ Phys Chem C2008113537543
   Google Scholar
• ArbabASWilsonLBAshariPJordanEKLewisBKFrankJAA model of lysosomal metabolism of dextran coated superpara-magnetic iron oxide (SPIO) nanoparticles: implications for cellular magnetic resonance imagingNMR Biomed20051838338916013087
   PubMed Web of Science ®Google Scholar
• MahmoudiMSimchiAImaniMMilaniASStroevePAn in vitro study of bare and poly(ethylene glycol)-co-fumarate-coated super-paramagnetic iron oxide nanoparticles: a new toxicity identification procedureNanotechnology20092022510419433870
   PubMed Web of Science ®Google Scholar
• PisanicTR2ndBlackwellJDShubayevVIFiñonesRRJinSNanotoxicity of iron oxide nanoparticle internalization in growing neuronsBiomaterials2007282572258117320946
   PubMed Web of Science ®Google Scholar
• TalelliMRijckenCJFLammersTSuperparamagnetic iron oxide nanoparticles encapsulated in biodegradable thermosensitive polymeric micelles: toward a targeted nanomedicine suitable for image-guided drug deliveryLangmuir2009252060206719166276
   PubMed Web of Science ®Google Scholar
• XuZWangCYangWDengYFuSEncapsulation of nanosized magnetic iron oxide by polyacrylamide via inverse miniemulsion polymerizationJ Magn Magn Mater2004277136143
   Google Scholar
• YuMKJeongYYParkJDrug-loaded superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivoAngew Chem Int Ed20084753625365
   PubMed Web of Science ®Google Scholar
• ZhangZFengS-SThe drug encapsulation efficiency, in vitro drug release, cellular uptake and cytotoxicity of paclitaxel-loaded poly(lactide)-tocopheryl polyethylene glycol succinate nanoparticlesBiomaterials2006274025403316564085
   PubMed Web of Science ®Google Scholar
• GulsenDChauhanAOphthalmic drug delivery through contact lensesInvest Ophthalmol Vis Sci2004452342234715223815
   PubMed Web of Science ®Google Scholar
• GulsenDChauhanADispersion of microemulsion drops in HEMA hydrogel: a potential ophthalmic drug delivery vehicleInt J Pharm20052929511715725557
   PubMed Web of Science ®Google Scholar
• KimJConwayAChauhanAExtended delivery of ophthalmic drugs by silicone hydrogel contact lensesBiomaterials2008292259226918289662
   PubMed Web of Science ®Google Scholar
• PengC-CChauhanAExtended cyclosporine delivery by silicone-hydrogel contact lensesJ Control Release201115426727421745507
   PubMed Web of Science ®Google Scholar
• YangJLeeJKangJHollow silica nanocontainers as drug delivery vehiclesLangmuir2008243417342118324841
   PubMed Web of Science ®Google Scholar
• FinnieKSBartlettJRBarbéCJKongLFormation of silica nanoparticles in microemulsionsLangmuir2007233017302417300209
   PubMed Web of Science ®Google Scholar
• CaiQLuoZ-SPangW-QFanY-WChenX-HCuiF-ZDilute solution routes to various controllable morphologies of MCM-41 silica with a basic mediumChem Mater200113258263
   Web of Science ®Google Scholar
• HuhSWienchJWYooJ-CPruskiMLinVS-YOrganic functionalization and morphology control of mesoporous silicas via a co-condensation synthesis methodChem Mater20031542474256
   Web of Science ®Google Scholar
• GreenDLinJLamY-FHuMZ-CSchaeferDWHarrisMSize, volume fraction, and nucleation of Stober silica nanoparticlesJ Colloid Interface Sci200326634635814527458
   PubMed Web of Science ®Google Scholar
• SadasivanSKhushalaniDMannSSynthesis and shape modification of organo-functionalised silica nanoparticles with ordered mesostructured interiorsJ Mater Chem20031310231029
   Web of Science ®Google Scholar
• XuHYanFMonsonEEKopelmanRRoom-temperature preparation and characterization of poly(ethylene glycol)-coated silica nanoparticles for biomedical applicationsJ Biomed Mater Res A200366A87087912926040
   PubMedGoogle Scholar
• RaduDRLaiC-YHuangJShuXLinVS-YFine-tuning the degree of organic functionalization of mesoporous silica nanosphere materials via an interfacially designed co-condensation methodChem Commun (Camb)2005101264126615742046
   PubMed Web of Science ®Google Scholar
• BagweRPHilliardLRTanWSurface modification of silica nanoparticles to reduce aggregation and nonspecific bindingLangmuir2006224357436216618187
   PubMed Web of Science ®Google Scholar
• HeQZhangJShiJThe effect of PEGylation of mesoporous silica nanoparticles on nonspecific binding of serum proteins and cellular responsesBiomaterials2010311085109219880176
   PubMed Web of Science ®Google Scholar
• LesotPChapuisSBayleJPStructural-dynamical relationship in silica PEG hybrid gelsJ Mater Chem19988147151
   Web of Science ®Google Scholar
• PeracchiaMFattalEDesmaëleDStealth® PEGylated polycy-anoacrylate nanoparticles for intravenous administration and splenic targetingJ Control Release19996012112810370176
   PubMed Web of Science ®Google Scholar
• BrandaFSilvestriBLucianiGCostantiniATescioneFSynthesis structure and stability of amino functionalized PEGylated silica nano-particlesColloids Surf Physicochem Eng Asp20103671216
   Google Scholar
• ZhangZBernsAEWillboldSBuitenhuisJSynthesis of poly(ethylene glycol) (PEG)-grafted colloidal silica particles with improved stability in aqueous solventsJ Colloid Interface Sci200731044645517346738
   PubMedGoogle Scholar
• ParkJ-HGuLvon MaltzahnGRuoslahtiEBhatiaSNSailorMJBiodegradable luminescent porous silicon nanoparticles for in vivo applicationsNat Mater2009833133619234444
   PubMed Web of Science ®Google Scholar
• PuseyPNToughRJDynamic light scattering, a probe of brownian particle dynamicsAdv Colloid Interface Sci198216143159
   Google Scholar
• BerriozabalGde MiguelYRSynthesis and characterisation of silica nanoparticles bearing different functional groups obtained via a two-stage methodPhys Status Solidi C2010726922696
   Google Scholar
• HudsonSPaderaRFLangerRKohaneDSThe biocompatibility of mesoporous silicatesBiomaterials2008294045405518675454
   PubMed Web of Science ®Google Scholar
• LiuTLiLTengXSingle and repeated dose toxicity of mesoporous hollow silica nanoparticles in intravenously exposed miceBiomaterials2011321657166821093905
   PubMed Web of Science ®Google Scholar
• KimYCaldwellJ-MBellamkondaRVNanoparticle-mediated local delivery of methylprednisolone after spinal cord injuryBiomaterials2009302582259019185913
   PubMed Web of Science ®Google Scholar
• CerqueiraSROliveiraJMSilvaNAMicroglia response and in vivo therapeutic potential of methylprednisolone-loaded dendrimer nanoparticles in spinal cord injurySmall20139573874923161735
   PubMedGoogle Scholar
• GaillardPJAppeldoornCCRipJEnhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammationJ Control Release201216436436922732475
   PubMed Web of Science ®Google Scholar
• ReijerkerkAAppeldoornCCRipJBoerM deGaillardPJSystemic treatment with glutathione PEGylated liposomal methylprednisolone (2B3-201) improves therapeutic efficacy in a model of ocular inflammationInvest Ophthalmol Vis Sci20145542788279424692123
   PubMedGoogle Scholar
• AnsariMAKellerJNScheffSWProtective effect of Pycnogenol in human neuroblastoma SH-SY5Y cells following acrolein-induced cytotoxicityFree Radic Biol Med2008451510151918822368
   PubMed Web of Science ®Google Scholar
• SinghMArseneaultMSandersonTMurthyVRamassamyCChallenges for research on polyphenols from foods in Alzheimer’s disease: bioavailability, metabolism, and cellular and molecular mechanismsJ Agric Food Chem2008564855487318557624
   PubMed Web of Science ®Google Scholar
• NamYChoiMHwangHNatural flavone jaceosidin is a neuroinflammation inhibitorPhytother Res201327340441122619052
   PubMedGoogle Scholar
• DubeANicolazzoJALarsonIChitosan nanoparticles enhance the plasma exposure of (−)-epigallocatechin gallate in mice through an enhancement in intestinal stabilityEur J Pharm Sci20114442242621925598
   PubMed Web of Science ®Google Scholar
• SmithAGiuntaBBickfordPCFountainMTanJShytleRDNanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer’s diseaseInt J Pharm201038920721220083179
   PubMed Web of Science ®Google Scholar
• ShutavaTGBalkundiSSVangalaPLayer-by-layer-coated gelatin nanoparticles as a vehicle for delivery of natural polyphenolsACS Nano200931877188519534472
   PubMed Web of Science ®Google Scholar
• SannaVPintusGRoggioAMTargeted biocompatible nanoparticles for the delivery of (−)-epigallocatechin 3-gallate to prostate cancer cellsJ Med Chem2011541321133221306166
   PubMed Web of Science ®Google Scholar
• ShutavaTGLvovYMEncapsulation of natural polyphenols with antioxidant properties in polyelectrolyte capsules and nanoparticlesDiederichMNoworytaKNatural Compounds as Inducers of Cell DeathDordrecht, The NetherlandsSpringer2012 Available from: http://link.springer.com/chapter/10.1007/978-94-007-4575-9_9Accessed November 21, 2013
   Google Scholar
• KhanNBharaliDJAdhamiVMOral administration of naturally occurring chitosan based nanoformulated green tea polyphenol EGCG effectively inhibits prostate cancer cell growth in a xenograft modelCarcinogenesis2013bgt321
   Google Scholar
• LemariéFChangCWBlatchfordDRAntitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administrationNanomedicine (Lond)2013818119222891867
   PubMedGoogle Scholar
• ChoYShiRBorgensRIvanisevicARepairing the damaged spinal cord and brain with nanomedicineSmall200841676168118798208
   PubMed Web of Science ®Google Scholar
• Tysseling-MattiaceVMSahniVNieceKLSelf-Assembling nanofibers inhibit glial scar formation and promote axon elongation after spinal cord injuryJ Neurosci2008283814382318385339
   PubMed Web of Science ®Google Scholar