Magnetic resonance hypointensive signal primarily originates from extracellular iron particles in the long-term tracking of mesenchymal stem cells transplanted in the infarcted myocardium

References

• CliffordDMFisherSABrunskillSJStem cell treatment for acute myocardial infarctionCochrane Database Syst Rev20122CD00653622336818
   PubMedGoogle Scholar
• SuncionVYGhersinEFishmanJEDoes transendocardial injection of mesenchymal stem cells improve myocardial function locally or globally?: An analysis from the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis (POSEIDON) randomized trialCirc Res201411481292130124449819
   PubMedGoogle Scholar
• HuuALPrakashSShum-TimDCellular cardiomyoplasty: current state of the fieldRegen Med20127457158222817629
   PubMedGoogle Scholar
• BarbashIMChouraquiPBaronJSystemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distributionCirculation2003108786386812900340
   PubMed Web of Science ®Google Scholar
• VandsburgerMCardiac cell tracking with MRI reporter genes: welcoming a new fieldCurr Cardiovasc Imaging Rep20147925024489982
   PubMedGoogle Scholar
• AzeneNFuYMaurerJKraitchmanDLTracking of stem cells in vivo for cardiovascular applicationsJ Cardiovasc Magn Reson2014161724406054
   PubMedGoogle Scholar
• HeGZhangHWeiHIn vivo imaging of bone marrow mesenchymal stem cells transplanted into myocardium using magnetic resonance imaging: a novel method to trace the transplanted cellsInt J Cardiol2007114141016759718
   PubMedGoogle Scholar
• QiCMMaGSLiuNFIdentification and differentiation of magnetically labeled mesenchymal stem cells in vivo in swines with myocardial infarctionInt J Cardiol2009131341741918055034
   PubMedGoogle Scholar
• ArbabASBashawLAMillerBRJordanEKBulteJWFrankJAIntracytoplasmic tagging of cells with ferumoxides and transfection agent for cellular magnetic resonance imaging after cell transplantation: methods and techniquesTransplantation20037671123113014557764
   PubMedGoogle Scholar
• ArbabASJordanEKWilsonLBYocumGTLewisBKFrankJAIn vivo trafficking and targeted delivery of magnetically labeled stem cellsHum Gene Ther200415435136015053860
   PubMed Web of Science ®Google Scholar
• KimYJHuhYMChoeKOIn vivo magnetic resonance imaging of injected mesenchymal stem cells in rat myocardial infarction; simultaneous cell tracking and left ventricular function measurementInt J Cardiovasc Imaging200925Suppl 19910919132547
   PubMedGoogle Scholar
• HuangZYGeJBYangSIn vivo cardiac magnetic resonance imaging of superparamagnetic iron oxides-labeled mesenchymal stem cells in swinesZhonghua Xin Xue Guan Bing Za Zhi2007354344349 Chinese17711662
   PubMedGoogle Scholar
• YangKXiangPZhangCMagnetic resonance evaluation of transplanted mesenchymal stem cells after myocardial infarction in swineCan J Cardiol201127681882522014624
   PubMedGoogle Scholar
• StuckeyDJCarrCAMartin-RendonEIron particles for noninvasive monitoring of bone marrow stromal cell engraftment into, and isolation of viable engrafted donor cells from, the heartStem Cells20062481968197516627684
   PubMedGoogle Scholar
• KawamuraMMiyagawaSFukushimaSEnhanced survival of transplanted human induced pluripotent stem cell-derived cardiomyocytes by the combination of cell sheets with the pedicled omental flap technique in a porcine heartCirculation201312811 Suppl 1S87S9424030425
   PubMed Web of Science ®Google Scholar
• TerrovitisJStuberMYoussefAMagnetic resonance imaging overestimates ferumoxide-labeled stem cell survival after transplantation in the heartCirculation2008117121555156218332264
   PubMed Web of Science ®Google Scholar
• AmsalemYMardorYFeinbergMSIron-oxide labeling and outcome of transplanted mesenchymal stem cells in the infarcted myocardiumCirculation200711611 Suppl138145
   Google Scholar
• EbertSNTaylorDGNguyenHLNoninvasive tracking of cardiac embryonic stem cells in vivo using magnetic resonance imaging techniquesStem Cells200725112936294417690182
   PubMed Web of Science ®Google Scholar
• LiZSuzukiYHuangMComparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjectsStem Cells200826486487318218820
   PubMed Web of Science ®Google Scholar
• AndersonLJWestwoodMAHoldenSMyocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonanceBr J Haematol2004127334835515491298
   PubMed Web of Science ®Google Scholar
• AmadoLCSaliarisAPSchuleriKHCardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarctionProc Natl Acad Sci U S A200510232114741147916061805
   PubMed Web of Science ®Google Scholar
• PittengerMFMackayAMBeckSCMultilineage potential of adult human mesenchymal stem cellsScience1999284541114314710102814
   PubMed Web of Science ®Google Scholar
• HuangZPeiNWangYDeep magnetic capture of magnetically loaded cells for spatially targeted therapeuticsBiomaterials20103182130214019995668
   PubMed Web of Science ®Google Scholar
• LindlTLewandowskiBSchreyöggSStaudteAAn evaluation of the in vitro cytotoxicities of 50 chemicals by using an electrical current exclusion method versus the neutral red uptake and MTT assaysAltern Lab Anim200533659160116372834
   PubMedGoogle Scholar
• KumarBMMaengGHLeeYMNeurogenic and cardiomyogenic differentiation of mesenchymal stem cells isolated from minipig bone marrowRes Vet Sci201293274975721985860
   PubMed Web of Science ®Google Scholar
• National Research Council (US) Institute for Laboratory Animal ResearchGuide for the Care and Use of Laboratory AnimalsWashington (DC)National Academies Press (US)1996
   Google Scholar
• HuangZGeJSunALigating LAD with its whole length rather than diagonal branches as coordinates is more advisable in establishing stable myocardial infarction model of swineExp Anim201059443143920660989
   PubMedGoogle Scholar
• KraitchmanDLHeldmanAWAtalarEIn vivo magnetic resonance imaging of mesenchymal stem cells in myocardial infarctionCirculation2003107182290229312732608
   PubMed Web of Science ®Google Scholar
• ZhangHSongPTangYInjection of bone marrow mesenchymal stem cells in the borderline area of infarcted myocardium: heart status and cell distributionJ Thorac Cardiovasc Surg200713451234124017976455
   PubMedGoogle Scholar
• WangPCShanLEssential elements to consider for MRI cell tracking studies with iron oxide-based labeling agentsJ Basic Clin Med2012111624159426
   PubMedGoogle Scholar
• ThorekDLTsourkasASize, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cellsBiomaterials200829263583359018533252
   PubMed Web of Science ®Google Scholar
• FröhlichEThe role of surface charge in cellular uptake and cytotoxicity of medical nanoparticlesInt J Nanomedicine201275577559123144561
   PubMed Web of Science ®Google Scholar
• SchlorfTMeinckeMKosselEGlüerCCJansenOMentleinRBiological properties of iron oxide nanoparticles for cellular and molecular magnetic resonance imagingInt J Mol Sci2010121122321339973
   PubMedGoogle Scholar
• NaqviSSamimMAbdinMConcentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stressInt J Nanomedicine2010598398921187917
   PubMed Web of Science ®Google Scholar
• GeGWuHXiongFThe cytotoxicity evaluation of magnetic iron oxide nanoparticles on human aortic endothelial cellsNanoscale Res Lett20138121523647620
   PubMed Web of Science ®Google Scholar
• CochranDBWattamwarPPWydraRSuppressing iron oxide nanoparticle toxicity by vascular targeted antioxidant polymer nanoparticlesBiomaterials201334379615962224016851
   PubMed Web of Science ®Google Scholar
• GujjaPRosingDRTripodiDJShizukudaYIron overload cardiomyopathy: better understanding of an increasing disorderJ Am Coll Cardiol201056131001101220846597
   PubMed Web of Science ®Google Scholar
• CokicIKaliAWangXIron deposition following chronic myocardial infarction as a substrate for cardiac electrical anomalies: initial findings in a canine modelPLoS One201389e7319324066038
   PubMedGoogle Scholar
• KaliAKumarACokicIChronic manifestation of postreperfusion intramyocardial hemorrhage as regional iron deposition: a cardiovascular magnetic resonance study with ex vivo validationCirc Cardiovasc Imaging20136221822823403335
   PubMedGoogle Scholar
• VoogdASluiterWvan EijkHGKosterJFLow molecular weight iron and the oxygen paradox in isolated rat heartsJ Clin Invest1992905205020551430227
   PubMed Web of Science ®Google Scholar
• HammBStaksTTaupitzMContrast-enhanced MR imaging of liver and spleen: first experience in humans with a new superparamagnetic iron oxideJ Magn Reson Imaging1994456596687981510
   PubMed Web of Science ®Google Scholar
• OnishiHMurakamiTKimTSafety of ferucarbotran in MR imaging of the liver: a pre- and postexamination questionnaire-based multicenter investigationJ Magn Reson Imaging200929110611119097079
   PubMedGoogle Scholar
• RichardsJMShawCALangNNIn vivo mononuclear cell tracking using superparamagnetic particles of iron oxide: feasibility and safety in humansCirc Cardiovasc Imaging20125450951722787016
   PubMed Web of Science ®Google Scholar
• HuangZPeiNShenYA novel method to delivery stem cells to the injured heart: spatially focused magnetic targeting strategyJ Cell Mol Med20121661203120522500918
   PubMedGoogle Scholar
• HuangZShenYPeiNThe effect of nonuniform magnetic targeting of intracoronary-delivering mesenchymal stem cells on coronary embolisationBiomaterials201334389905991624055521
   PubMedGoogle Scholar
• ChengKLiTSMalliarasKDavisDRZhangYMarbánEMagnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarctionCirc Res2010106101570158120378859
   PubMed Web of Science ®Google Scholar
• HuangZShenYSunAMagnetic targeting enhances retrograde cell retention in a rat model of myocardial infarctionStem Cell Res Ther20134614924330751
   PubMedGoogle Scholar
• BaronNKachenouraNCluzelPComparison of various methods for quantitative evaluation of myocardial infarct volume from magnetic resonance delayed enhancement dataInt J Cardiol2013167373974422459370
   PubMedGoogle Scholar