Enhanced oral bioavailability of fenofibrate using polymeric nanoparticulated systems: physicochemical characterization and in vivo investigation

References

• GuayDMicronized fenofibrate: a new fibric acid hypolipidemic agentAnn Pharmacother199933101083110310534222
   PubMed Web of Science ®Google Scholar
• GenestJJNguyenN-HTherouxPDavignonJCohnJSEffect of micronized fenofibrate on plasma lipoprotein levels and hemostatic parameters of hypertriglyceridemic patients with low levels of high-density lipoprotein cholesterol in the fed and fasted stateJ Cardiovasc Pharmacol200035116417210630748
   PubMed Web of Science ®Google Scholar
• MunozAGuichardJPReginaultPMicronised fenofibrateAtherosclerosis1994110suppl(0)S45S487857384
   PubMedGoogle Scholar
• Ming-ThauSChing-MinYSokoloskiTDCharacterization and dissolution of fenofibrate solid dispersion systemsInt J Pharm19941032137146
   Google Scholar
• DressmanJButlerJHempenstallJReppasCThe BCS: where do we go from here?Pharm Technol20012576877
   Google Scholar
• BadensEMajerikVHorváthGComparison of solid dispersions produced by supercritical antisolvent and spray-freezing technologiesInt J Pharm20093771–2253419442711
   PubMedGoogle Scholar
• CutlerLHowesCDeeksNJBuckTLJeffreyPDevelopment of a P-glycoprotein knockout model in rodents to define species differences in its functional effect at the blood–brain barrierJ Pharm Sci20069591944195316850390
   PubMedGoogle Scholar
• YoshihashiYIijimaHYonemochiETeradaKEstimation of physical stability of amorphous solid dispersion using differential scanning calorimetryJ Therm Anal Calorim2006853689692
   Web of Science ®Google Scholar
• GoddeerisCCoacciJVan den MooterGCorrelation between digestion of the lipid phase of smedds and release of the anti-HIV drug UC 781 and the anti-mycotic drug enilconazole from smeddsEur J Pharm Biopharm200766217318117158039
   PubMed Web of Science ®Google Scholar
• LeunerCDressmanJImproving drug solubility for oral delivery using solid dispersionsEur J Pharm Biopharm2000501476010840192
   PubMed Web of Science ®Google Scholar
• PerrutMJungJLeboeufFEnhancement of dissolution rate of poorly-soluble active ingredients by supercritical fluid processes: part I: micronization of neat particlesInt J Pharm2005288131015607252
   PubMed Web of Science ®Google Scholar
• JiaZLinPXiangYA novel nanomatrix system consisted of colloidal silica and pH-sensitive polymethylacrylate improves the oral bioavailability of fenofibrateEur J Pharm Biopharm201179112613421658449
   PubMed Web of Science ®Google Scholar
• XingFChengGYiKMaLNanoencapsulation of capsaicin by complex coacervation of gelatin, acacia, and tanninsJ Appl Polym Sci200596622252229
   Web of Science ®Google Scholar
• Mora-HuertasCFessiHElaissariAPolymer-based nanocapsules for drug deliveryInt J Pharm2010385111314219825408
   PubMedGoogle Scholar
• Pinto ReisCNeufeldRJRibeiroAJVeigaFNanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticlesNanomedicine20062182117292111
   PubMed Web of Science ®Google Scholar
• SoppimathKSAminabhaviTMKulkarniARRudzinskiWEBiodegradable polymeric nanoparticles as drug delivery devicesJ Control Release200170112011166403
   PubMed Web of Science ®Google Scholar
• HengDCutlerDJChanH-KYunJRaperJAWhat is a suitable dissolution method for drug nanoparticles?Pharm Res20082571696170118320295
   PubMed Web of Science ®Google Scholar
• VauthierCBouchemalKMethods for the preparation and manufacture of polymeric nanoparticlesPharm Res20092651025105819107579
   PubMed Web of Science ®Google Scholar
• Quintanar-GuerreroDAllémannEFessiHDoelkerEPreparation techniques and mechanisms of formation of biodegradable nanoparticles from preformed polymersDrug Dev Ind Pharm19982412111311289876569
   PubMed Web of Science ®Google Scholar
• BroadheadJEdmond RouanSRhodesCThe spray drying of pharmaceuticalsDrug Dev Ind Pharm19921811–1211691206
   Web of Science ®Google Scholar
• ChauhanBShimpiSParadkarAPreparation and evaluation of glibenclamide-polyglycolized glycerides solid dispersions with silicon dioxide by spray drying techniqueEur J Pharm Sci200526221923016087324
   PubMed Web of Science ®Google Scholar
• JoeJHLeeWMParkYJEffect of the solid-dispersion method on the solubility and crystalline property of tacrolimusInt J Pharm20103951–216116620580799
   PubMed Web of Science ®Google Scholar
• PeltonenLValoHKolakovicRLaaksonenTHirvonenJElectrospraying, spray drying and related techniques for production and formulation of drug nanoparticlesExpert Opin Drug Deliv20107670571920345326
   PubMed Web of Science ®Google Scholar
• Van DroogeDHinrichsWVisserMFrijlinkHCharacterization of the molecular distribution of drugs in glassy solid dispersions at the nanometer scale, using differential scanning calorimetry and gravimetric water vapour sorption techniquesInt J Pharm2006310122022916427226
   PubMedGoogle Scholar
• ChiouWLRiegelmanSPharmaceutical applications of solid dispersion systemsJ Pharm Sci1971609128113024935981
   PubMed Web of Science ®Google Scholar
• JizomotoHKanaokaESugitaKHiranoKGelatin–acacia microcapsules for trapping micro-oil droplets containing lipophilic drugs and ready disintegration in the gastrointestinal tractPharm Res1993108111511228415395
   PubMed Web of Science ®Google Scholar
• BáezJOlsenDPolarekJRecombinant microbial systems for the production of human collagen and gelatinAppl Microbiol Biotechnol200569324525216240115
   PubMedGoogle Scholar
• PiaoMGYangCWLiDXPreparation and in vivo evaluation of piroxicam-loaded gelatin microcapsule by spray drying techniqueBiol Pharm Bull20083161284128718520070
   PubMed Web of Science ®Google Scholar
• MentingLHoogstadBThijssenHDiffusion coefficients of water and organic volatiles in carbohydrate-water systemsInt J Food Sci Technol197052111126
   Google Scholar
• ThijssenHACFlavour retention in drying preconcentrated food liquidsJ Appl Chem Biotechnol19712112372377
   Google Scholar
• LiDXYanYDOhDHDevelopment of valsartan-loaded gelatin microcapsule without crystal change using hydroxypropylmethylcellulose as a stabilizerDrug Deliv201017532232920367177
   PubMed Web of Science ®Google Scholar
• Mehmood YousafAWuk KimDChoiH-GOhEValidation of a highly sensitive RP-HPLC method for quantification of fenofibrate in pure and pharmaceutical dosage formsCurr Pharm Anal201410297104
   Google Scholar
• StammASethPinventorLabaratoires Fournier, assigneeFenofibrate pharmaceutical composition having high bioavailabilty and method for preparing itGoogle patents US62774052001 Available from: http://www.google.com/patents/US6277405
   Google Scholar
• ShahVPNooryANooryCIn vitro dissolution of sparingly water-soluble drug dosage formsInt J Pharm1995125199106
   Google Scholar
• SanganwarGPGuptaRBDissolution-rate enhancement of fenofibrate by adsorption onto silica using supercritical carbon dioxideInt J Pharm20083601–221321818550302
   PubMed Web of Science ®Google Scholar
• WindbergsMStrachanCJKleinebuddePUnderstanding the solid-state behaviour of triglyceride solid lipid extrudates and its influence on dissolutionEur J Pharm Biopharm2009711808718588976
   PubMed Web of Science ®Google Scholar
• OhDHParkY-JKangJHYongCSChoiH-GPhysicochemical characterization and in vivo evaluation of flurbiprofen-loaded solid dispersion without crystalline changeDrug Deliv2011181465320726805
   PubMed Web of Science ®Google Scholar
• Society of ToxicologyGuiding Principles in the Use of Animals in ToxicologyReston, VASociety of Toxicology2008
   Google Scholar
• LiXGuLXuYWangYPreparation of fenofibrate nanosuspension and study of its pharmacokinetic behavior in ratsDrug Dev Ind Pharm200935782783319466879
   PubMed Web of Science ®Google Scholar
• StrakaRJBurkhardtRTFisherJEDetermination of fenofibric acid concentrations by HPLC after anion exchange solid-phase extraction from human serumTher Drug Monit200729219720217417074
   PubMed Web of Science ®Google Scholar
• StreelBHubertPCeccatoADetermination of fenofibric acid in human plasma using automated solid-phase extraction coupled to liquid chromatographyJ Chromatogr B Biomed Sci Appl2000742239140010901144
   PubMed Web of Science ®Google Scholar
• TangNLaiJChenYLuYWuWFenofibrate solid dispersion pellets prepared by fluid-bed coating: physical characterization, improved dissolution and oral bioavailability in beagle dogsJ China Pharm Sci2009182156161
   Google Scholar
• DaveRHPatelHHDonahueEPatelADTo evaluate the change in release from solid dispersion using sodium lauryl sulfate and model drug sulfathiazoleDrug Dev Ind Pharm201339101562157223030270
   PubMed Web of Science ®Google Scholar
• GiriTKBadwaikHAlexanderATripathiDKSolubility enhancement of ibuprofen in the presence of hydrophilic polymer and surfactantInt J Appl Biol Pharm Tech201012793800
   Google Scholar
• KimMSKimJSParkHJChoWKChaK-HHwangSJEnhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent processInt J Nanomedicine20116299722162657
   PubMed Web of Science ®Google Scholar
• LeaneMMSinclairWQianFFormulation and process design for a solid dosage form containing a spray-dried amorphous dispersion of ibipinabantPharm Dev Technol201318235936622268601
   PubMed Web of Science ®Google Scholar
• MoesJKoolenSHuitemaASchellensJBeijnenJNuijenBPharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxelInt J Pharm2011420224425021907780
   PubMed Web of Science ®Google Scholar
• HancockBParksMWhat is the true solubility advantage for amorphous pharmaceuticals?Pharm Res200017439740410870982
   PubMed Web of Science ®Google Scholar
• MüllerBWBraunsUSolubilization of drugs by modified β-cyclodextrinsInt J Pharm1985261–27788
   Google Scholar
• PithaJPithaJAmorphous water-soluble derivatives of cyclodextrins: nontoxic dissolution enhancing excipientsJ Pharm Sci19857499879904067854
   PubMed Web of Science ®Google Scholar
• Antoniadou-VyzaEBucktonGMichaleasSGLoukasYLEfentakisMThe formation of an inclusion complex of methocarbamol with hydroxypropyl-β-cyclodextrin: the effect on chemical stability, solubility and dissolution rateInt J Pharm19971582233239
   Google Scholar
• IrieTUekamaKPharmaceutical applications of cyclodextrins III. Toxicological issues and safety evaluationJ Pharm Sci19978621471629040088
   PubMed Web of Science ®Google Scholar
• MiroAQuagliaFGianniniLCappelloBImmacolata La RotondaMDrug/cyclodextrin solid systems in the design of hydrophilic matrices: a strategy to modulate drug delivery rateCurr Drug Deliv20063437337817076639
   PubMedGoogle Scholar
• SethiaSSquillanteESolid dispersion of carbamazepine in PVP K30 by conventional solvent evaporation and supercritical methodsInt J Pharm20042721–211015019063
   PubMed Web of Science ®Google Scholar
• Van Den BulckeAIBogdanovBDe RoozeNSchachtEHCornelissenMBerghmansHStructural and rheological properties of methacrylamide modified gelatin hydrogelsBiomacromolecules200011313811709840
   PubMed Web of Science ®Google Scholar
• DjabourovMPaponPInfluence of thermal treatments on the structure and stability of gelatin gelsPolymer1983245537542
   Google Scholar
• CraigDQThe mechanisms of drug release from solid dispersions in water-soluble polymersInt J Pharm2002231213114411755266
   PubMed Web of Science ®Google Scholar
• PoutonCWFormulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification systemEur J Pharm Sci2006293–427828716815001
   PubMed Web of Science ®Google Scholar
• TaylorLZografiGSpectroscopic characterization of interactions between PVP and indomethacin in amorphous molecular dispersionsPharm Res19971412169116989453055
   PubMed Web of Science ®Google Scholar
• DohertyCYorkPAccelerated stability of an X-Ray amorphous frusemide-polyvinylpyrrolidone solid dispersionDrug Dev Ind Pharm1989151219691987
   Web of Science ®Google Scholar
• RegeBDYuLXHussainASPolliJEEffect of common excipients on Caco-2 transport of low-permeability drugsJ Pharm Sci200190111776178611745735
   PubMedGoogle Scholar
• BriseidGBriseidKKirkevoldKIncreased intestinal absorption in the rat caused by sodium lauryl sulphate, and its possible relation to the cAMP systemNaunyn Schmiedebergs Arch Pharmacol19762922137144181680
   PubMedGoogle Scholar
• MillerJMBeigAKriegBJThe solubility–permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeationMol Pharm2011851848185621800883
   PubMed Web of Science ®Google Scholar
• DaiW-GDongLCSongY-QNanosizing of a drug/carrageenan complex to increase solubility and dissolution rateInt J Pharm2007342120120717560055
   PubMedGoogle Scholar
• MuraPCirriMFaucciMGinès-DoradoJBettinettiGInvestigation of the effects of grinding and co-grinding on physicochemical properties of glisentideJ Pharm Biomed Anal200230222723712191707
   PubMedGoogle Scholar
• YonemochiEKitaharaSMaedaSYamamuraSOguchiTYamamotoKPhysicochemical properties of amorphous clarithromycin obtained by grinding and spray dryingEur J Pharm Sci1999743313389971917
   PubMed Web of Science ®Google Scholar
• KuboHMizobeMImprovement of dissolution rate and oral bioavailability of a sparingly water-soluble drug, (+/−)-5-[[2-(2-naphthalenylmethyl)-5-benzoxazolyl] methyl]-2,4-thiazolidinedione, in co-ground mixture with D-mannitolBiol Pharm Bull1997204604639145232
   PubMed Web of Science ®Google Scholar
• PurvisTVaughnJMRogersTLCryogenic liquids, nanoparticles, and microencapsulationInt J Pharm20063241435016814968
   PubMedGoogle Scholar
• ChowAHHsiaCKGordonJDYoungJWVargha-ButlerEIAssessment of wettability and its relationship to the intrinsic dissolution rate of doped phenytoin crystalsInt J Pharm199512612128
   Google Scholar
• KawashimaYSaitoMTakenakaHImprovement of solubility and dissolution rate of poorly water-soluble salicylic acid by a spray-drying techniqueJ Pharm Pharmacol197527115235608
   PubMedGoogle Scholar