70
Views
12
CrossRef citations to date
0
Altmetric
Original Research

A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency

, , , , , , & show all
Pages 2673-2683 | Published online: 01 Apr 2015

References

  • CouvreurPBarrattGFattalELegrandPVauthierCNanocapsule technology: a reviewCrit Rev Ther Drug Carrier Syst20021929913412197610
  • GloverDJLippsHJJansDATowards safe, non-viral therapeutic gene expression in humansNat Rev Genet20056429931015761468
  • LoveKTMahonKPLevinsCGLipid-like materials for low-dose, in vivo gene silencingProc Natl Acad Sci U S A201010751864186920080679
  • Schmidt-WolfGDSchmidt-WolfIGNon-viral and hybrid vectors in human gene therapy: an updateTrends Mol Med200392677212615040
  • SempleSCAkincAChenJRational design of cationic lipids for siRNA deliveryNat Biotechnol201028217217620081866
  • SheridanCGene therapy finds its nicheNat Biotechnol201129212112821301435
  • TagalakisADDiakonovIAGrahamIRApolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient miceBiochim Biophys Acta20051686319019915629688
  • YinHKanastyRLEltoukhyAAVegasAJDorkinJRAndersonDGNon-viral vectors for gene-based therapyNat Rev Genet201415854155525022906
  • ZhangYSatterleeAHuangLIn vivo gene delivery by nonviral vectors: overcoming hurdles?Mol Ther20122071298130422525514
  • AnchordoquyTJArmstrongTKMolinaMDLow molecular weight dextrans stabilize nonviral vectors during lyophilization at low osmolalities: concentrating suspensions by rehydration to reduced volumesJ Pharm Sci20059461226123615858857
  • GrosseSMTagalakisADMustapaMFTumor-specific gene transfer with receptor-mediated nanocomplexes modified by polyethylene glycol shielding and endosomally cleavable lipid and peptide linkersFASEB J20102472301231320203088
  • ManuntaMDMcAnultyRJTagalakisADNebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epitheliumPLoS One2011610e2676822046351
  • TagalakisADGrosseSMMengQHIntegrin-targeted nanocomplexes for tumour specific delivery and therapy by systemic administrationBiomaterials20113251370137621074847
  • TagalakisADMcAnultyRJDevaneyJA receptor-targeted nanocomplex vector system optimized for respiratory gene transferMol Ther200816590791518388925
  • KennyGDBienemannASTagalakisADMultifunctional receptor-targeted nanocomplexes for the delivery of therapeutic nucleic acids to the brainBiomaterials201334369190920023948162
  • TagalakisADKennyGDBienemannASPEGylation improves the receptor-mediated transfection efficiency of peptide-targeted, self-assembling, anionic nanocomplexesJ Control Release201417417718724269968
  • DuZMunyeMMTagalakisADManuntaMDHartSLThe role of the helper lipid on the DNA transfection efficiency of lipopolyplex formulationsSci Rep20144710725407686
  • MengQHIrvineSTagalakisADMcAnultyRJMcEwanJRHartSLInhibition of neointimal hyperplasia in a rabbit vein graft model following non-viral transfection with human iNOS cDNAGene Ther2013201097998623636244
  • TagalakisADHeLSaraivaLGustafssonKTHartSLReceptor-targeted liposome-peptide nanocomplexes for siRNA deliveryBiomaterials201132266302631521624650
  • TagalakisADSaraivaLMcCarthyDGustafssonKTHartSLComparison of nanocomplexes with branched and linear peptides for siRNA deliveryBiomacromolecules201314376177023339543
  • TagalakisADLeeDHDBienemannASMultifunctional, self-assembling anionic peptide-lipid nanocomplexes for targeted siRNA deliveryBiomaterials201435298406841524985735
  • KennyGDVillegas-LlerenaCTagalakisADMultifunctional receptor-targeted nanocomplexes for magnetic resonance imaging and transfection of tumoursBiomaterials201233297241725022809644
  • CouvreurPVauthierCNanotechnology: intelligent design to treat complex diseasePharm Res20062371417145016779701
  • AcebalCCSimonetBMValcárcelMNanoparticles and continuous-flow systems combine synergistically or preconcentrationTrAC Trends in Analytical Chemistry201343109120
  • BelliveauNMHuftJLinPJMicrofluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNAMol Ther Nucleic Acids20121e3723344179
  • DaviesLANunez-AlonsoGAHebelHLA novel mixing device for the reproducible generation of nonviral gene therapy formulationsBiotechniques201049366666820854270
  • ValenciaPMFarokhzadOCKarnikRLangerRMicrofluidic technologies for accelerating the clinical translation of nanoparticlesNat Nanotechnol201271062362923042546
  • VauthierCCabaneBLabarreDHow to concentrate nanoparticles and avoid aggregation?Eur J Pharm Biopharm200869246647518396389
  • ZelphatiONguyenCFerrariMFelgnerJTsaiYFelgnerPLStable and monodisperse lipoplex formulations for gene deliveryGene Ther199859127212829930330
  • KumarPWuHMcBrideJLTransvascular delivery of small interfering RNA to the central nervous systemNature20074487149394317572664
  • ColeSLVassarRThe role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiologyJ Biol Chem200828344296212962518650431
  • GoldeTEDicksonDHuttonMFilling the gaps in the abeta cascade hypothesis of Alzheimer’s diseaseCurr Alzheimer Res20063542143017168641
  • Alvarez-ErvitiLSeowYYinHBettsCLakhalSWoodMJDelivery of siRNA to the mouse brain by systemic injection of targeted exosomesNat Biotechnol201129434134521423189
  • KimSSYeCKumarPTargeted delivery of siRNA to macrophages for anti-inflammatory treatmentMol Ther2010185993100120216529
  • ZadranSAkopianGZadranHWalshJBaudryMRVG-mediated calpain2 gene silencing in the brain impairs learning and memoryNeuromolecular Med2013151748122903378
  • GaoYWangZYZhangJRVG-peptide-linked trimethylated chitosan for delivery of siRNA to the brainBiomacromolecules20141531010101824547943
  • KimJYChoiWIKimYHTaeGBrain-targeted delivery of protein using chitosan- and RVG peptide-conjugated, pluronic-based nano-carrierBiomaterials20133441170117823122677
  • BoboRHLaskeDWAkbasakAMorrisonPFDedrickRLOldfieldEHConvection-enhanced delivery of macromolecules in the brainProc Natl Acad Sci U S A1994916207620808134351
  • GillSSPatelNKHottonGRDirect brain infusion of glial cell line-derived neurotrophic factor in Parkinson diseaseNat Med20039558959512669033
  • RohnSSuttkusAArendtTUeberhamURVG peptide as transfection reagent for specific cdk4 gene silencing in vitro and in vivoJ Drug Target201220438138822443811
  • WhiteEBienemannAMegrawLBunnunCGillSEvaluation and optimization of the administration of a selectively replicating herpes simplex viral vector to the brain by convection-enhanced deliveryCancer Gene Ther201118535836921372854