Antibody-mediated targeting of iron oxide nanoparticles to the folate receptor alpha increases tumor cell association in vitro and in vivo

References

• HowladerNNooneAMKrapchoMSEER Cancer Statistics Review, 1975–2011, National Cancer InstituteBethesda, MDNational Cancer Institute2014 Available from: http://seer.cancer.gov/csr/1975_2011/Accessed November 27, 2014
   Google Scholar
• ZeeVdHeating the patient: a promising approachAnnals of Oncology2002131173118412181239
   PubMed Web of Science ®Google Scholar
• MorozPJonesSKGrayBNMagnetically mediated hyperthermia: current status and future directionsInt J Hyperthermia20021826728412079583
   PubMed Web of Science ®Google Scholar
• ItoAShinkaiMHondaHWakabayashiTYoshidaJKobayashiTAugmentation of MHC class I antigen presentation via heat shock protein expression by hyperthermiaCancer Immunol Immunother20015051552211776373
   PubMed Web of Science ®Google Scholar
• ItoAShinkaiMHondaHHeat shock protein 70 expression induces an antitumor immunity during intracellular hyperthermia using magnetite nanoparticlesCancer Immunol Immunother200352808812594571
   PubMed Web of Science ®Google Scholar
• Toraya-BrownSSheenMRBairdJRPhagocytes mediate targeting of iron oxide nanoparticles to tumors for cancer therapyIntegr Biol (Camb)20135115917122935885
   PubMedGoogle Scholar
• GilchristRKMedalRShoreyWDHanselmanRCParrottJCTaylorCBSelective inductive heating of lymph nodesAnn Surg195714659660613470751
   PubMed Web of Science ®Google Scholar
• IvkovRDeNardoSJDaumWApplication of high amplitude alternating magnetic fields for heat induction of nanoparticles localized in cancerClin Cancer Res2005117093S7103S16203808
   PubMed Web of Science ®Google Scholar
• ItoAShinkaiMHondaHKobayashiTMedical application of functionalized magnetic nanoparticlesJ Biosci Bioeng200510011116233845
   PubMed Web of Science ®Google Scholar
• DennisCLJacksonAJBorchersJANearly complete regression of tumors via collective behavior of magnetic nanoparticles in hyperthermiaNanotechnology2009203939510319726837
   PubMed Web of Science ®Google Scholar
• FortinJPWilhemCServaisJMénagerCBacriJCGazeauFSize-sorted anionic iron oxide nanomagnets as colloidal mediators for magnetic hyperthermiaJ Am Chem Soc200712992628263517266310
   PubMed Web of Science ®Google Scholar
• TaratulaODaniRKSchumannCMultifunctional nanomedicine platform for concurrent delivery of chemotherapeutic drugs and mild hyperthermia to ovarian cancer cellsInt J Pharm201345816918024091153
   PubMed Web of Science ®Google Scholar
• WeitmanSDLarkRHConeyLRDistribution of the folate receptor GP38 in normal and malignant cells lines and tissuesCancer Res199252339634011596899
   PubMed Web of Science ®Google Scholar
• Garin-ChesaPCampbellISaigoPELewisJLJrOldLJRettigWJTrophoblast and ovarian cancer antigen LK26. Sensitivity and specificity in immunopathology and molecular identification as a folate-binding proteinAm J Pathol19931425575678434649
   PubMed Web of Science ®Google Scholar
• KraisAWortmannLHermannsLTargeted uptake of folic acid-functionalized iron oxide nanoparticles by ovarian cancer cells in the presence but not in the absence of serumNanomedicine20141071421143124491397
   PubMed Web of Science ®Google Scholar
• QuanGDuXHuoTTargeted molecular imaging of antigen OC183B2 in ovarian cancers using MR molecular probesAcad Radiol2010171468147620869887
   PubMed Web of Science ®Google Scholar
• PrantnerAMNguyenCVSchollerNFacile immunotargeting of nanoparticles against tumor antigens using site-specific biotinylated antibody fragmentsJ Biomed Nanotechnol20139101686169724015498
   PubMed Web of Science ®Google Scholar
• KamenBASmithAKFarletuzumab, an anti-folate receptor alpha antibody, does not block binding of folate or anti-folates to receptor nor does it alter the potency of anti-folates in vitroCancer Chemother Pharmacol201270111312022644798
   PubMed Web of Science ®Google Scholar
• MarchettiCPalaiaIGiorginiMTargeted drug delivery via folate receptors in recurrent ovarian cancer: a reviewOnco Targets Ther201471223123625031539
   PubMed Web of Science ®Google Scholar
• EbelWRouthierELFoleyBPreclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alphaCancer Immun20077617346028
   PubMedGoogle Scholar
• SpannuthWALynYGMerrittWMTherapeutic efficacy of folate receptor alpha blockade with MORAb-003 in ovarian cancerGynecol Oncol2008108S135
   Web of Science ®Google Scholar
• SpannuthWASoodAKColemanRLFarletuzumab in epithelial ovarian carcinomaExpert Opin Biol Ther201010343143720092424
   PubMed Web of Science ®Google Scholar
• ArmstrongDKWhiteAJWeilSCPhillipsMColemanRLFarletuzumab (a monoclonal antibody against folate receptor alpha) in relapsed platinum-sensitive ovarian cancerGynecol Oncol201312945245823474348
   PubMed Web of Science ®Google Scholar
• WallaceTPHarrisWJCarrFJRettigWJGarin-ChesaPLloydJinventorsSloan-Kettering Cancer Center, assigneeRecombinant human anti-LK26 antibodiesUnited States patent US 59524841999914
   Google Scholar
• MarksJDAmersdorferPGerenILouJRazaiAConsuelosMGinventorsThe Regents Of The University Of California assigneeTherapeutic monoclonal antibodies that neutralize botulinum neurotoxinsUnited States patent US 20080124328A12008529
   Google Scholar
• NdongCTateJAKettWCTumor cell targeting by iron oxide nanoparticles is dominated by different factors in vitro versus in vivoPLoS One2015102e011563625695795
   PubMed Web of Science ®Google Scholar
• KekaloKABakerIinventorsEngineering DCTSo, assigneeMagnetic nanoparticles, composites, suspensions and colloids with high specific absorption rate (SAR)United States patent WO 2014089464 A12014612
   Google Scholar
• LiuHGaza-BulsecoGFalduDChumsaeCSunJHeterogeneity of monoclonal antibodiesJ Pharm Sci20089772426244717828757
   PubMed Web of Science ®Google Scholar
• HumphreysDHeywoodSPHenryAAlternative antibody Fab’ fragment PEGylation strategies: combination of strong reducing agents, disruption of the interchain disulphide bond and disulphide engineeringProtein Eng Des Sel200720522723417452434
   PubMed Web of Science ®Google Scholar
• GuptaAKGuptaMSynthesis and surface engineering of iron oxide nanoparticles for biomedical applicationsBiomaterials2005263995402115626447
   PubMed Web of Science ®Google Scholar
• KohlerNSunCWangJZhangMMethotrexate-modified superparamagnetic nanoparticles and their intracellular uptake into human cancer cellsLangmuir2005218858886416142971
   PubMed Web of Science ®Google Scholar
• LeeHLeeEKimDKJangNKJeongYYJonSAntibiofouling polymer-coated superparamagnetic iron oxide nanoparticles as potential magnetic resonance contrast agents for in vivo cancer imagingJ Am Chem Soc20061287383738916734494
   PubMed Web of Science ®Google Scholar
• van VlerkenLEAmijiMMMulti-functionnal polymeric nanoparticles for tumor-targeted drug deliveryExpert Opin Drug Deliv20063220521616506948
   PubMedGoogle Scholar
• LeeJHHuhYMJunYWArtificially engineered magnetic nanoparticles for ultra-sensitive molecular imagingNat Med2007131959917187073
   PubMed Web of Science ®Google Scholar
• PengX-HQianXMaoHTargeted magnetic iron oxide nanoparticles for tumor imaging and therapyInt J Nanomedicine20083331132118990940
   PubMed Web of Science ®Google Scholar
• ColeAJYangVCDavidAECancer theranostics: the rise of targted magnetic nanoparticlesTrends Biotechnol201129732333221489647
   PubMedGoogle Scholar
• LaurentSMahmoudiMSuperparamagnetic iron oxide nanoparticles: promises for diagnosis and treatment of cancerInt J Mol Epidemiol Genet20112436739022199999
   PubMedGoogle Scholar
• TassaCShawSYWeisslederRDextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapyAcc Chem Res2011441084285221661727
   PubMed Web of Science ®Google Scholar
• KaakiKHervé-AubertKChiperMMagnetic nanocarriers of doxorubicin coated with poly(ethylene glycol) and folic acid: Relation between coating strucutre, surface properties, colloidal stability and cancer cell targetingLangmuir2012281496150522172203
   PubMedGoogle Scholar
• RosenJEChanLShiehDBGuFXIron oxide nanoparticles for targeted cancer imaging and diagnosticsNanomedicine2012827529021930108
   PubMed Web of Science ®Google Scholar
• IttrichHPeldschusKRaabeNKaulMAdamGSuperparmagnetic iron oxide nanoparticles in biomedicine: applications and developments in diagnostics and therapyRofo20131851149116624008761
   PubMedGoogle Scholar
• KiruiDKKhalidovIWangYBattCATargeted near-IR hybrid magnetic nanoparticles for in vivo cancer therpay and imagingNanomedicine2013970271123219875
   PubMed Web of Science ®Google Scholar
• ThomasRParkI-KJeongYYMagnetic iron oxide nanoparticles for multimodal imaging and therapy of cancerInt J Mol Sci201314159101593023912234
   PubMed Web of Science ®Google Scholar
• YenSKPadmanabhanPSelvanSTMultifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule deliveryTheranostics2013312986100324396508
   PubMed Web of Science ®Google Scholar
• CortajarenaALOrtegaDOcampoSMEngineering Iron oxide nanoparticles for clinical settingsNanobiomed20141258841
   Google Scholar
• WablerMZhuWHedayatiMMagnetic resonance imaging contrast of iron oxide nanoparticles developed for hyperthermia is dominated by iron contentInt J Hyperthermia201430319220024773041
   PubMed Web of Science ®Google Scholar
• SilvaACOliveiraTRMamamiJBApplication of hyperthermia induced by superparamagnetic iron oxide nanoparticles in glioma treatmentInt J Nanomedicine2011659160321674016
   PubMed Web of Science ®Google Scholar
• HilgerIIn vivo applications of magnetic nanoparticles hyperthermiaInt J Hyperthermia201329882883424219800
   PubMed Web of Science ®Google Scholar
• HuangHSHainfeldJFIntravenous magnetic nanoparticles cancer hyperthermiaInt J Nanomedicine201382521253223901270
   PubMed Web of Science ®Google Scholar
• IvkovRMagnetic nanoparticles hyperthermia: a new frontier in biology and medicineInt J Hyperthermia201329870370524219798
   PubMed Web of Science ®Google Scholar
• PetrykAAGiustiniAJGottesmanREKaufmanPAHoopesPJMagnetic nanoparticle hyperthermia enhancement of cisplatin chemotherapy cancer treatmentInt J Hyperthermia20132984585124144336
   PubMed Web of Science ®Google Scholar
• PetrykAAGiustiniAJGottesmanRETremblyBSHoopesPJComparison of magnetic nanoparticles and microwave hyperthermia cancer treatment methology and treatment effect in a rodent breast cancer modelInt J Hyperthermia20132981982724219799
   PubMed Web of Science ®Google Scholar
• Toraya-BrownSSheenMRZhangPLocal hyperthermia of tumors induces CD8(+) T cell-mediated resistance against distal and secondary tumorsNanomedicine20141061273128524566274
   PubMed Web of Science ®Google Scholar
• KossatzSLudwigRDähringHHigh therapeutic efficiency of magnetic hyperthermia in xenograft models achieved with moderate temperature dosages in tumor areaPharm Res2014313274328824890197
   PubMed Web of Science ®Google Scholar
• MarthelyLHHouZDengYHuman reduced folate carrier: translation of basic biology to cancer etiology and therapyCancer Metastasis Rev200726111112817334909
   PubMedGoogle Scholar
• MarthelyLHHouZStructure and function of the reduced folate carrier: a paradigm of a major facilitator superfamily mammalian nutrient transporterVitam Horm20087914518418804694
   PubMedGoogle Scholar
• QiuAJansenMSakarisAIdentification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorptionCell2006127591792817129779
   PubMed Web of Science ®Google Scholar
• HilgerIDietmarELinßWStrecSKaiserWADevelopments for the minimally invasive treatment of tumours by targted magnetic heatingJ Phys: Condens Mat200618S2951S2958
   Web of Science ®Google Scholar
• ZhangJPDewildeAHChinnPHerceptin-directed nanoparticles activated by an alternating magnetic field slectively kill HER-2 positive human breast cells in vitro via hyperthermiaInt J Hyperthermia20112768269721992561
   PubMed Web of Science ®Google Scholar
• WahajuddinAroraSSuperparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriersInt J Nanomedicine201273445347122848170
   PubMed Web of Science ®Google Scholar