129
Views
19
CrossRef citations to date
0
Altmetric
Original Research

Cetuximab-conjugated iron oxide nanoparticles for cancer imaging and therapy

, &
Pages 3663-3685 | Published online: 20 May 2015

References

  • GrandisJRSokJCSignaling through the epidermal growth factor receptor during the development of malignancyPharmacol Ther20041021374615056497
  • HarrisALNicholsonSSainsburyRWrightCFarndonJEpidermal growth factor receptor and other oncogenes as prognostic markersJ Natl Cancer Inst Monogr1992111811871627426
  • AngKKBerkeyBATuXImpact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinomaCancer Res200262247350735612499279
  • Rubin GrandisJMelhemMFGoodingWELevels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survivalJ Natl Cancer Inst199890118248329625170
  • KimESKhuriFRHerbstRSEpidermal growth factor receptor biology (IMC-C225)Curr Opin Oncol200113650651311673692
  • Van CutsemEKohneCHHitreECetuximab and chemotherapy as initial treatment for metastatic colorectal cancerN Engl J Med2009360141408141719339720
  • Van CutsemEKohneCHLangICetuximab plus irinotecan, fluo-rouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation statusJ Clin Oncol201129152011201921502544
  • No authors listedCetuximab approved by FDA for treatment of head and neck squamous cell cancerCancer Biol Ther20065434034216808060
  • MendelsohnJBlockade of receptors for growth factors: an anticancer therapy – the fourth annual Joseph H Burchenal American Association for Cancer Research Clinical Research Award LectureClin Cancer Res20006374775310741693
  • CiardielloFTortoraGEGFR antagonists in cancer treatmentN Engl J Med2008358111160117418337605
  • FanZMasuiHAltasIMendelsohnJBlockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodiesCancer Res19935318432243288364927
  • FanZLuYWuXMendelsohnJAntibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cellsJ Biol Chem19942694427595276027961676
  • PrewettMRockwellPRockwellRFThe biologic effects of C225, a chimeric monoclonal antibody to the EGFR, on human prostate carcinomaJ Immunother Emphasis Tumor Immunol19961964194279041461
  • HuangS-MBockJMHarariPMEpidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neckCancer Res19995981935194010213503
  • HuangS-MHarariPMModulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesisClin Cancer Res2000662166217410873065
  • BrunsCJHarbisonMTDavisDWEpidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanismsClin Cancer Res2000651936194810815919
  • PerrottePMatsumotoTInoueKAnti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude miceClin Cancer Res19995225726510037173
  • WuXFanZMasuiHRosenNMendelsohnJApoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulinJ Clin Invest1995954189719057706497
  • PengDFanZLuYDeBlasioTScherHMendelsohnJAnti-epidermal growth factor receptor monoclonal antibody 225 up-regulates p27KIP1 and induces G1 arrest in prostatic cancer cell line DU145Cancer Res19965616366636698706005
  • BonnerJARaischKPTrummellHQEnhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancersJ Clin Oncol20001821 Suppl 1S47S53
  • BandyopadhyayDMandalMAdamLMendelsohnJKumarRPhysical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cellsJ Biol Chem19982733156815739430697
  • NaramuraMGilliesSDMendelsohnJReisfeldRAMuellerBMTherapeutic potential of chimeric and murine anti-(epidermal growth factor receptor) antibodies in a metastasis model for human melanomaCancer Immunol Immunother19933753433498402738
  • KuraiJChikumiHHashimotoKAntibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell linesClin Cancer Res20071351552156117332301
  • CondeJBaoCCuiDBaptistaPVTianFAntibody-drug gold nanoantennas with Raman spectroscopic fingerprints for in vivo tumour theranosticsJ Control Release2014183879324704711
  • KarmaniLLabarDValemboisVAntibody-functionalized nanoparticles for imaging cancer: influence of conjugation to gold nanoparticles on the biodistribution of 89Zr-labeled cetuximab in miceContrast Media Mol Imaging20138540240823740810
  • KaoHWLinYYChenCCBiological characterization of cetuximab-conjugated gold nanoparticles in a tumor animal modelNanotechnology [serial on the Internet]. Available from: http://iopscience.iop.org/0957-4484/25/29/295102/Accessed February 28, 2015
  • FerrucciJTStarkDDIron oxide-enhanced MR imaging of the liver and spleen: review of the first 5 yearsAJR Am J Roentgenol199015559439502120963
  • MuraSCouvreurPNanotheranostics for personalized medicineAdv Drug Deliv Rev201264131394141622728642
  • YuMKParkJJonSTargeting strategies for multifunctional nanopar-ticles in cancer imaging and therapyTheranostics20122134422272217
  • VillanuevaACaneteMRocaAGThe influence of surface functionalization on the enhanced internalization of magnetic nanoparticles in cancer cellsNanotechnology [serial on the Internet]. Available from: http://iopscience.iop.org/0957-4484/20/11/115103/Accessed February 3, 2015
  • LaConteLENitinNZurkiyaOCoating thickness of magnetic iron oxide nanoparticles affects R2 relaxivityJ Magn Reson Imaging20072661634164117968941
  • LaurentSForgeDPortMMagnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applicationsChem Rev200810862064211018543879
  • PatelDLahijiAPatelSMonoclonal antibody cetuximab binds to and down-regulates constitutively activated epidermal growth factor receptor vIII on the cell surfaceAnticancer Res2007275A3355336617970081
  • BhattacharyyaSBhattacharyaRCurleySMcNivenMAMukherjeePNanoconjugation modulates the trafficking and mechanism of antibody induced receptor endocytosisProc Natl Acad Sci U S A201010733145411454620679244
  • CampbellKSInventorFox Chase Cancer Center, assigneeGenetically modified human natural killer cell linesUnited States patent US831394311202012
  • BailonPWonCYPEG-modified biopharmaceuticalsExpert Opin Drug Deliv20096111619236204
  • FuertgesFAbuchowskiAThe clinical efficacy of poly(ethylene glycol)-modified proteinsJ Control Release1990111–3139148
  • ZalipskySChemistry of polyethylene glycol conjugates with biologically active moleculesAdv Drug Deliv Rev1995162–3157182
  • PapahadjopoulosDAllenTMGabizonASterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacyProc Natl Acad Sci U S A1991882411460114641763060
  • LeeRJLowPSDelivery of liposomes into cultured KB cells via folate receptor-mediated endocytosisJ Biol Chem19942695319832048106354
  • HadjipanayisCGMachaidzeRKaluzovaMEGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance imaging-guided convection-enhanced delivery and targeted therapy of glioblastomaCancer Res201070156303631220647323
  • SunadaHMagunBEMendelsohnJMacLeodCLMonoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylationProc Natl Acad Sci U S A19868311382538292424012
  • JaramilloMLLeonZGrotheSPaul-RocBAbulrobAO’Connor McCourtMEffect of the anti-receptor ligand-blocking 225 monoclonal antibody on EGF receptor endocytosis and sortingExp Cell Res2006312152778279016806168
  • FriedmanLMRinonASchechterBSynergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapyProc Natl Acad Sci U S A200510261915192015684082
  • SpanglerJBNeilJRAbramovitchSCombination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recyclingProc Natl Acad Sci U S A201010730132521325720616078
  • SunQMingLThomasSMPUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cellsOncogene200928242348235719421143
  • ZhuHCaoXAli-OsmanFKeirSLoHWEGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activityCancer Lett2010294110111020153921
  • WeihuaZTsanRHuangWCSurvival of cancer cells is maintained by EGFR independent of its kinase activityCancer Cell200813538539318455122
  • ParkEJChoiDHKimYMagnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cellsToxicol In Vitro20142881402141225086211
  • NaqviSSamimMAbdinMConcentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stressInt J Nanomedicine2010598398921187917
  • ArnoldJNWormaldMRSimRBRuddPMDwekRAThe impact of glycosylation on the biological function and structure of human immunoglobulinsAnnu Rev Immunol200725215017029568