Some inferences from in vivo experiments with metal and metal oxide nanoparticles: the pulmonary phagocytosis response, subchronic systemic toxicity and genotoxicity, regulatory proposals, searching for bioprotectors (a self-overview)

References

• KatsnelsonBAPrivalovaLIDegtyarevaTDExperimental estimates of the toxicity of iron oxide Fe3O4 (magnetite) nanoparticlesCentral European Journal of Occupational and Environmental Medicine2010164763
   Google Scholar
• KatsnelsonBAPrivalovaLIKuzminSVSome peculiarities of pulmonary clearance mechanisms in rats after intratracheal instillation of magnetite (Fe3O4) suspensions with different particle sizes in the nano-meter and micrometer ranges: Are we defenseless against nanoparticles?Int J Occup Environ Health201016450852421222393
   PubMed Web of Science ®Google Scholar
• KatsnelsonBADegtyarevaTDMinigalievaIISub-chronic systemic toxicity and bio-accumulation of Fe3O4 nano- and microparticles following repeated intraperitoneal administration to ratsInt J Toxicol20113016067
   Google Scholar
• KatsnelsonBAPrivalovaLIKuzminSVAn approach to tentative reference levels setting for nanoparticles in the workroom air based on comparing their toxicity with that of their micrometric counterparts: A case study of iron oxide Fe3O4ISRN Nanotechnol2012201212
   Google Scholar
• KatsnelsonBAPrivalovaLISutunkovaMPUptake of some metallic nanoparticles by, and their impact on pulmonary macrophages in vivo as viewed by optical, atomic force, and transmission electron microscopyJ Nanomed Nanotechnol2012318
   Google Scholar
• KatsnelsonBAPrivalovaLISutunkovaMPInteraction of iron oxide Fe3O4 nanoparticles and alveolar macrophages in vivoBull Exp Biol Med201215262762922803151
   PubMedGoogle Scholar
• KatsnelsonBAPrivalovaLIGurvichVBComparative in vivo assessment of some adverse bio-effects of equidimensional gold and silver nanoparticles and the attenuation of nanosilver’s effects with a complex of innocuous bioprotectorsInt J Mol Sci20131422449248323354478
   PubMed Web of Science ®Google Scholar
• PrivalovaLIKatsnelsonBALoginovaNVSubchronic Toxicity of Copper Oxide Nanoparticles and Its Attenuation with the Help of a Combination of BioprotectorsInt J Mol Sci2014157123791240625026171
   PubMed Web of Science ®Google Scholar
• PrivalovaLIKatsnelsonBALoginovaNVSome Characteristics of Free Cell Population in the Airways of Rats after Intratracheal Instillation of Copper-Containing Nano-Scale ParticlesInt J Mol Sci20141511215382155325421246
   PubMedGoogle Scholar
• KatsnelsonBAMinigalievaIAPrivalovaLILower airways response in rats to a single or combined intratracheal instillation of manganese and nickel nanoparticles and its attenuation with a bio-protective pre-treatmentToksicol Vestnik20146814
   Google Scholar
• ZhuMTFengWYWangBComparative study of pulmonary responses to nano- and submicron ferric oxide in ratsToxicology20082472–310211118394769
   PubMed Web of Science ®Google Scholar
• MahmoudiMSimchiAMilaniASStroevePCell toxicity of superparamagnetic iron oxide nanoparticlesJ Colloid Interface Sci2009336251051819476952
   PubMed Web of Science ®Google Scholar
• MahmoudiMLaurentSShokrgozarMAHosseinkhaniMToxicity Evaluations of Superparamagnetic Iron Oxide Nanoparticles: Cell “Vision” versus Physicochemical Properties of NanoparticlesACS Nano2011597263727621838310
   PubMed Web of Science ®Google Scholar
• NaqviSSamimMAbdinMZConcentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stressInt J Nanomedicine2010598398921187917
   PubMed Web of Science ®Google Scholar
• WuXTanYMaoHZhangMToxic effects of iron oxide nanoparticles on human umbilical vein endothelial cellsInt J Nanomedicine2010538539920957160
   PubMed Web of Science ®Google Scholar
• SinghNJenkinsGJAsadiRDoakSHPotential toxicity of superparamagnetic iron oxide nanoparticles (SPION)Nano Rev201015358
   PubMedGoogle Scholar
• SoenenSJDe CuyperMDe SmedtSCBraeckmansKInvestigating the toxic effects of iron oxide nanoparticlesMethods Enzymol201250919522422568907
   PubMed Web of Science ®Google Scholar
• LiuGGaoJAiHChenXApplications and potential toxicity of magnetic iron oxide nanoparticlesSmall201399–101533154523019129
   PubMed Web of Science ®Google Scholar
• MarkidesHRotherhamMEl HajAJBiocompatibility and Toxicity of Magnetic Nanoparticles in Regenerative MedicineJ Nanomater20122012614094
   Web of Science ®Google Scholar
• BarhoumiLDewezDToxicity of Superparamagnetic Iron Oxide Nanoparticles on Green Alga Chlorella vulgarisBio Med Research International20132013647974
   Google Scholar
• AhamedMKarnsMGoodsonMDNA damage response to different surface chemistry of silver nanoparticles in mammalian cellsToxicol Appl Pharmacol2008233340441018930072
   PubMed Web of Science ®Google Scholar
• AroraSJainJRajwadeJMPaknikarKMInteractions of silver nanoparticles with primary mouse fibroblasts and liver cellsToxicol Appl Pharmacol2009236331031819269301
   PubMed Web of Science ®Google Scholar
• TricklerWJLantzSMMurdockRCSilver nanoparticle induced blood–brain barrier inflammation and increased permeability in primary rat brain micro vessel endothelial cellsToxicol Sci2010118116017020713472
   PubMed Web of Science ®Google Scholar
• LiTAlbeeBAlemayehuMComparative toxicity study of Ag, Au, Ag-Au bimetallic nanoparticles on Daphnia magnaAnal Bioanal Chem2010398268970020577719
   PubMedGoogle Scholar
• ParkEJBaeEYiYRepeated-dose toxicity and inflammatory responses in mice by oral administration of silver nano-particlesEnviron Toxicol Pharmacol201030216216821787647
   PubMed Web of Science ®Google Scholar
• ParkMVNeighAMVermeulenJPThe effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticlesBiomaterials201132369810981721944826
   PubMed Web of Science ®Google Scholar
• ChoiJEKimSAhnJHInduction of oxidative stress and apoptosis by silver nanoparticles in the liver of adult zebrafishAquat Toxicol2010100215115920060176
   PubMed Web of Science ®Google Scholar
• KimYSSongMYParkJDSubchronic oral toxicity of silver nanoparticlesParticle and Fibre Toxicology201072020691052
   PubMed Web of Science ®Google Scholar
• AhmadiFKordestanyAHInvestigation on silver retention in different organs and oxidative stress enzymes in male broiler fed diet supplemented with powder of nano silverAm-Euras J Toxicol Sci2011312835
   Google Scholar
• StebounovaLVAdamcakova-DoddAKimJSNanosilver induces minimal lung toxicity or inflammation in a subacute murine inhalation modelParticle and Fibre Toxicology201181521266073
   PubMed Web of Science ®Google Scholar
• SrivastavaMSinghSSelfWTExposure to silver nanoparticles inhibits selenoprotein synthesis and the activity of thioredoxin reductaseEnviron Health Perspect2011120566121965219
   PubMedGoogle Scholar
• HackenbergSScherzedAKesslerMSilver nanoparticles: Evaluation of DNA damage, toxicity and functional impairment in human mesenchymal stem cellToxicol Lett20112011273321145381
   PubMed Web of Science ®Google Scholar
• FoldbjergRDangDAAutrupHCytotoxicity and genotoxicity of silver nanoparticles in the human lung cancer cell line, A549Arch Toxicol201185774375020428844
   PubMed Web of Science ®Google Scholar
• KimHRKimMJLeeSYOhSMChungKHGenotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cellsMutat Res2011726212913521945414
   PubMed Web of Science ®Google Scholar
• LiYChenDHYanJChenYGenotoxicity of silver nanoparticles evaluated using the Ames test and in vitro micronucleus assayMutat Res20127451–241022138422
   PubMedGoogle Scholar
• TavaresPBalbinoFMartins de OliveiraHEvaluation of genotoxic effect of silver nanoparticles (Ag-NPs) in vitro and in vivoJ Nanopart Res201214791
   Web of Science ®Google Scholar
• AsareNInstanesCSandbergWJCytotoxic and genotoxic effects of silver nanoparticles in testicular cellToxicology20122911–3657222085606
   PubMed Web of Science ®Google Scholar
• FlowerNABrabuBRevathyMCharacterization of synthesized silver nanoparticles and assessment of its genotoxicity potentials using the alkaline comet assayMutat Res20127421–2616522178963
   PubMedGoogle Scholar
• KarlssonHGligaARKohonenPWallbergbPFadeelBGenotoxicity and epigenetic effects of silver nanoparticlesToxicol Lett2012211SupplementS40
   Google Scholar
• LimDHJangJKimSKangTLeeKChoiIHThe effects of sub-lethal concentrations of silver nanoparticles on inflammatory and stress in human macrophages using cDNA microarray analysisBiomaterials201233184690469922459196
   PubMedGoogle Scholar
• BeerCFoldbjergRHayashiYSutherlandDSAutrupHToxicity of silver nanoparticles – Nanoparticle or silver ion?Toxicol Lett2012208328629222101214
   PubMed Web of Science ®Google Scholar
• CronholmPKarlssonHLHedbergJIntracellular uptake and toxicity of Ag and CuO nanoparticles: A comparison between nanoparticles and their corresponding metal ionsSmall20138797098223296910
   PubMedGoogle Scholar
• GomesTAraújoOPereiraRAlmeidaACCravoABebiannoMJGenotoxicity of copper oxide and silver nanoparticles in the mussel Mytilus galloprovincialisMar Environ Res201384515923294529
   PubMed Web of Science ®Google Scholar
• AhamedMAlSalhiMSSiddiquiMKSilver nanoparticles applications and human healthClin Chim Acta201041123–241841118420719239
   PubMed Web of Science ®Google Scholar
• SinghSD’BrittoVPrabhuneAARamanaCVDhawanAPrasadBLCytotoxic and genotoxic assessment of glycolipid-reduced and -capped gold and silver nanoparticlesNew J Chem201034294301
   Web of Science ®Google Scholar
• BakriSJPulidoJSMukerjeePMarlerRJMukhopadhyayDAbsence of histologic retinal toxicity of intravitreal nanogold in a rabbit modelRetina200828114714918185152
   PubMed Web of Science ®Google Scholar
• PanYLeifertARuauDGold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damageSmall20095182067207619642089
   PubMed Web of Science ®Google Scholar
• ChenYSHungYCHuangGSAssessment of the in vivo toxicity of gold nanoparticlesNanoscale Res Lett20094885886420596373
   PubMed Web of Science ®Google Scholar
• BalasurbamanianSKJittiwatJManikandanJOngCNYuLEOngWYBiodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in ratsBiomaterials20103182034204220044133
   PubMedGoogle Scholar
• ZhangQHitchinsVMSchrandAMHussainSMGoeringPLUptake of gold nanoparticles in murine macrophage cells without cytotoxicity or production of pro-inflammatory mediatorsNanotoxicology20105328429520849214
   PubMedGoogle Scholar
• LiJJLoSLNgCTGenomic instability of gold nanoparticle treated human lung fibroblast cellsBiomaterials201132235515552321543115
   PubMed Web of Science ®Google Scholar
• TricklerWJLantzSMMurdockRCBrain microvessel endothelial cells responses to gold microparticles: In vitro pro-inflammatory mediators and permeabilityNanotoxicology20115447949221175299
   PubMed Web of Science ®Google Scholar
• GlazerESZhuCHamirANBorneAThompsonCSCurleySABiodistribution and acute toxicity of naked gold nanoparticles in a rabbit hepatic tumor modelNanotoxicology20115445946820854190
   PubMed Web of Science ®Google Scholar
• MustafaTWatanabeFMonroeWImpact of gold nanoparticle concentration on their cellular uptake by MC3T3-E1 mouse osteoblastic cells as analyzed by transmission electron microscopyJ Nanomed Nanotechnol2011218
   Google Scholar
• RudolfRFriedrichBStopicSAnzelITomicSColicMCytotoxicity of gold nanoparticles prepared by ultrasonic spray pyrolysisJ Biomater Appl201226559561220819920
   PubMedGoogle Scholar
• DykmanLKhlebtsovNGold nanoparticles in biomedical applications: Recent advances and perspectivesChem Soc Rev20124162256228222130549
   PubMed Web of Science ®Google Scholar
• ChoiSYJeongSJangSHIn vitro toxicity of serum protein-adsorbed citrate-reduced gold nanoparticles in human lung adenocarcinoma cellsToxicology in Vitro201226222923722178767
   PubMedGoogle Scholar
• ShulzMMa-HockLBrillSInvestigation on the genotoxicity of different sizes of gold nanoparticles administered to the lungs of ratsMutat Res20127451–2515722172426
   PubMedGoogle Scholar
• AkhtarMJKumarSAlhadlaqHAAlrokayanSAAbu-SalahKMAhamedMDose-dependent genotoxicity of copper oxide nanoparticles stimulated by reactive oxygen species in human lung epithelial cellsToxicol Ind Health Epub2013125
   Google Scholar
• ChenZMengHXingGAcute toxicological effects of copper nanoparticles in vivoToxicol Lett2006163210912016289865
   PubMed Web of Science ®Google Scholar
• KarlssonHLCronholmPGustafssonJMöllerLCopper oxide nanoparticles are highly toxic: A comparison between metal oxide nanoparticles and carbon nanotubesChem Res Toxicol20082191726173218710264
   PubMed Web of Science ®Google Scholar
• StuderAMLimbachLKvan DucLNanoparticle cytotoxicity depends on intracellular solubility: comparison of stabilized copper metal and degradable copper oxide nanoparticlesToxicol Lett2010197316917420621582
   PubMed Web of Science ®Google Scholar
• BondarenkoOIvaskAKäkinenAKahruASub-toxic effects of CuO nanoparticles on bacteria: Kinetics, role of Cu ions and possible mechanisms of actionEnviron Pollut2012169818922694973
   PubMed Web of Science ®Google Scholar
• PangCSelckHMisraSKEffects of sediment-associated copper to the deposit-feeding snail, Potamopyrgus antipodarum: A comparison of Cu added in aqueous form or as nano- and micro-CuO particlesAquat Toxicol2012106–107114122
   PubMed Web of Science ®Google Scholar
• MagayeRZhaoJBowmanLDingMGenotoxicity and carcinogenicity of cobalt-, nickel- and copper-based nanoparticlesExp Ther Med20124455156123170105
   PubMed Web of Science ®Google Scholar
• AlarifiSAliDVermaAAlakhtaniSAliBACytotoxicity and genotoxicity of copper oxide nanoparticles in human skin keratinocytes cellsInt J Toxicol201332429630723667135
   PubMed Web of Science ®Google Scholar
• XuJLiZXuPXiaoLYangZNanosized copper oxide induces apoptosis through oxidative stress in podocytesArch Toxicol20138761067107322903339
   PubMed Web of Science ®Google Scholar
• CuillelMChevalletMCharbonnierPInterference of CuO nanoparticles with metal homeostasis in hepatocytes under sub-toxic conditionsNanoscale2014631707171524343273
   PubMed Web of Science ®Google Scholar
• ZhangQYukinoriKSatoKNakakukiKKoyahamaNDonaldsonKDifferences in the extent of inflammation caused by intratracheal exposure to three ultrafine metals: Role of free radicalsJ Toxicol Environ Health A19985364234389537280
   PubMed Web of Science ®Google Scholar
• ZhangQYukinoriKZhuXComparative toxicity of standard nickel and ultrafine nickel after intratracheal instillationJ Occup Health2003451233014605425
   PubMed Web of Science ®Google Scholar
• MagayeRZhaoJRecent progress in studies of metallic nickel and nickel-based nanoparticles’ genotoxicity and carcinogenicityEnvironmental Toxicology and Pharmacology201234364465023000472
   PubMed Web of Science ®Google Scholar
• MorimotoYHirohashiMOgamiAPulmonary toxicity following an intratracheal instillation of nickel oxide nanoparticle agglomeratesJournal of Occupational Health201153429329521597233
   PubMed Web of Science ®Google Scholar
• CapassoLCamatiniMGualtieriMNickel oxide nanoparticles induce inflammation and genotoxic effect in lung epithelial cellsToxicol Lett20142261283424503009
   PubMed Web of Science ®Google Scholar
• HussainSMJavorinaAKSchrandAMDuhartHMAliSFSchlagerJJThe Interaction of Manganese Nanoparticles with PC-12 Cells Induces Dopamine DepletionToxicol Sci200692245646316714391
   PubMed Web of Science ®Google Scholar
• SinghSPKumariMKumariSIRahmanMFMahboobMGroverPToxicity assessment of manganese oxide micro and nanoparticles in Wistar rats after 28 days of repeated oral exposureJ Appl Toxicol201333101165117923702825
   PubMed Web of Science ®Google Scholar
• BellusciMLa BarberaAPadellaFBiodistribution and acute toxicity of a nanofluid containing manganese iron oxide nanoparticles produced by a mechanochemical processInt J of Nanomedicine201491919192924790434
   PubMed Web of Science ®Google Scholar
• KatsnelsonBAKonyshevaLKPrivalovaLYMorosovaKIDevelopment of a multicompartmental model of the kinetics of quartz dust in the pulmonary region of the lung during chronic inhalation exposure of ratsBr J Ind Med19924931721811554613
   PubMedGoogle Scholar
• GeiserMKreylingWGDeposition and biokinetics of inhaled nano-particlesParticle and Fibre Toxicology20107220205860
   PubMed Web of Science ®Google Scholar
• International Commission on Radiological Protection [homepage on the Internet]ICRP Publication 66: Human respiratory tract model for radiological protection. A report of a Task Group of the International Commission on Radiological Protection1994 Available from: http://www.icrp.org/publication.asp?id=ICRP Publication 66Accessed February 27, 2015
   Google Scholar
• KreylingWGGeiserMDosimetry of inhaled nanoparticlesMarijnissenJCGradonLNanoparticles in Medicine and Environment, Inhalation and Health EffectsSpringer Science and Business Media2009145173
   Google Scholar
• FröhlichESalar-BehzadiSToxicological assessment of inhaled nanoparticles: Role of in vivo, ex vivo, in vitro, and in silico studiesInt J Mol Sci20141534795482224646916
   PubMed Web of Science ®Google Scholar
• SadauskasEWallinHStolenbergMKupffer cells are central in the removal of nanoparticles from the organismPart Fibre Toxicol20074101617949501
   PubMedGoogle Scholar
• Lasagna-ReevesCGonzalez-RomeroDBarriaMABioaccumulation and toxicity of gold nanoparticles after repeated administration in miceBiochem Biophys Res Commun2010393464965520153731
   PubMed Web of Science ®Google Scholar
• RylovaMLMethods of Investigating Long-Term Effects of Noxious Environmental Agents in Animal ExperimentsLeningradMeditsina1964
   Google Scholar
• AdeyemiOOYemitanOKTaiwoAENeurosedative and muscle-relaxant activities of ethyl acetate extract of Baphianitida nitida AFZELJ Ethnopharmacol2006106331231616516421
   PubMed Web of Science ®Google Scholar
• FernandezSPWasowskiCLoscalzoLMCentral nervous system depressant action of flavonoid glycosideEur J Pharmacol2006539316817616698011
   PubMed Web of Science ®Google Scholar
• DonaldsonKStoneVTranCKKreylingWBormPJNanotoxicology (editorial)Occup Environ Med20046172772815317911
   PubMed Web of Science ®Google Scholar
• OberdörsterGOberdörsterEOberdörsterJNanotoxicology: an emerging discipline evolving from studied of ultrafine particlesEnviron Health Perspect2005113782383916002369
   PubMed Web of Science ®Google Scholar
• FadeelBClear and present danger? Engineered nanoparticles and the immune systemSwiss Med Wkly2012142w1360922736064
   PubMed Web of Science ®Google Scholar
• KilburnKHAlveolar clearance of particles. A bullfrog lung modelArch Environ Health19691845565635773990
   PubMed Web of Science ®Google Scholar
• RenwickLCBrownDClouterKDonaldsonKIncreased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle typesOccup Environ Med200461544244715090666
   PubMed Web of Science ®Google Scholar
• StoegerTReinhardCTakenakaSInstillation of six different ultrafine carbon particles indicates a surface area threshold dose for acute lung inflammation in miceEnviron Health Perspect2006114332833316507453
   PubMed Web of Science ®Google Scholar
• GrassianVHO’ShaughnessyPTAdamcakova-DoddAPettiboneJMThornePSInhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nmEnviron Health Perspect2007115339740217431489
   PubMed Web of Science ®Google Scholar
• SagerTMPorterDWRobinsonVALindsleyWGSchwegler-BerryVACastranovaVImproved method to disperse nanoparticles in vitro and in vivo investigation of toxicityNanotoxicology200712118129
   Web of Science ®Google Scholar
• WarheitDBReedKLSayesCMA role for surface reactivity in TiO2 and quartz-related nanoparticle pulmonary toxicityNanotoxicology200933181187
   Web of Science ®Google Scholar
• PrivalovaLIKatsnelsonBAOsipenkoABYushkovBHBabushkinaLGResponse of a phagocyte cell system to products of macrophage breakdown as a probable mechanism of alveolar phagocytosis adaptation to deposition of particles of different cytotoxicityEnviron Health Perspect1980352052186997028
   PubMed Web of Science ®Google Scholar
• PrivalovaLIKatsnelsonBAYelnichnykhLNSome peculiarities of the pulmonary phagocytotic response, dust kinetics, and silicosis development during long term exposure of rats to high quartz levelsBr J Ind Med19874442282353032230
   PubMedGoogle Scholar
• KatsnelsonBAPrivalovaLIRecruitment of phagocytizing cells into the respiratory tract as a response to the cytotoxic action of deposited particlesEnviron Health Perspect1984553133256376104
   PubMed Web of Science ®Google Scholar
• KatsnelsonBAKonyschevaLKSharapovaNyePrivalovaLIPrediction of the comparative intensity of pneumoconiotic changes caused by chronic inhalation exposure to dusts of different cytotoxicity by means of a mathematical modelOccup Environ Med19945131731808130845
   PubMedGoogle Scholar
• KatsnelsonBAKonyshevaLKPrivalovaLYSharapovaNYQuartz dust retention in rat lungs under chronic exposure simulated by a multicompartmental model: Further evidence of the key role of the cytotoxicity of quartz particlesInhalation Toxicology199798703715
   Google Scholar
• BastusNGCasalsESocorroVCPuntesVReactivity of engineered inorganic nanoparticles and carbon nanostructures in biological mediaNanotoxicology20082399112
   Web of Science ®Google Scholar
• FröhlichECellular targets and mechanisms in the cytotoxic action of non-biodegradable engineered nanoparticlesCurr Drug Metab201314997698824160294
   PubMed Web of Science ®Google Scholar
• PrivalovaLIKatsnelsonBASharapovaNYKislitsinaNSOn the relationship between activation and the breakdown of macrophages in pathogenesis of silicosisMed Lav19958665115218815362
   PubMedGoogle Scholar
• YokelRAMacPhailRCEngineered nanomaterials: exposures, hazards, and risk preventionJ Occup Med Toxicol20116721418643
   PubMed Web of Science ®Google Scholar
• MurashovVShultePGeraciCHowardJRegulatory approaches to worker protection in nanotechnology industry in the USA and European UnionInd Health201149328029621372443
   PubMedGoogle Scholar
• GroscoAPetri-FinkAMagrezARedikerMMeyerTManagement of nanomaterials safety in research environmentPart Fibre Toxicol201074021143952
   PubMedGoogle Scholar
• van BroekhuizenPDealing with uncertainties in the nanotech workplace practice: making the precautionary approach operationalJ Biomed Nanotechnol201171151721485779
   PubMedGoogle Scholar
• Centers for Disease Control and Prevention [homepage on the Internet]Current Intelligence Bulletin 63: Occupational Exposure to Titanium Dioxide. CDC and NIOSHUS Department of Health and Human Services2011 Available from: http://www.cdc.gov/niosh/docs/2011-160/Accessed February 27, 2015
   Google Scholar
• KatsnelsonBAKuzminSVDegtyarevaTDPrivalovaLISoloboyevaJI“Biological prophylaxis” – One of the ways to proceed from the analytical environmental epidemiology to the population health protectionCent Eur J Occup Environ Med2008144142
   Google Scholar
• KatsnelsonBAPrivalovaLIGurvichVBEnhancing Population’s Resistance to Toxic Exposures as an Auxilliary Tool of Decreasing Environmental and Occupational Health Risks (a Self-Overview)Journal of Environmental Protection2014514351449
   Google Scholar