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Original Research

Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice

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Pages 5049-5057 | Published online: 06 Aug 2015

References

  • YangJLjnJAdvance on study in anti-tumor mechamism of bererine (Ber)Zhongguo Zhong Yao Za Zhi20073210881883934 Chinese17655135
  • TangJFengYTsaoSWangNCurtainRWangYBerberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigationsJ Ethnopharmacol2009126151719686830
  • YinJGaoZLiuDLiuZYeJBerberine improves glucose metabolism through induction of glycolysisAm J Physiol Endocrinol Metab20082941E148E15617971514
  • LiXLiZXueMFructus Xanthii attenuates hepatic steatosis in rats fed on high-fat dietPLoS One201384e6149923585904
  • HuaWDingLChenYGongBHeJXuGDetermination of berberine in human plasma by liquid chromatography-electrospray ionization-mass spectrometryJ Pharm Biomed Anal200744493193717531424
  • LiuYHaoHXieHLvHLiuCWangGOxidative demethylenation and subsequent glucuronidation are the major metabolic pathways of berberine in ratsJ Pharm Sci200998114391440119283771
  • LiuYTHaoHPXieHGExtensive intestinal first-pass elimination and predominant hepatic distribution of berberine explain its low plasma levels in ratsDrug Metab Dispos201038101779178420634337
  • AjazuddinSarafSApplications of novel drug delivery system for herbal formulationsFitoterapia201081768068920471457
  • XueMYangMXZhangWCharacterization, pharmacokinetics, and hypoglycemic effect of berberine loaded solid lipid nanoparticlesInt J Nanomedicine201384677468724353417
  • LazoMClarkJMThe epidemiology of nonalcoholic fatty liver disease: a global perspectiveSemin Liver Dis200828433935018956290
  • BrowningJDHortonJDMolecular mediators of hepatic steatosis and liver injuryJ Clin Invest2004114214715215254578
  • JaskiewiczKRzepkoRSledzinskiZFibrogenesis in fatty liver associated with obesity and diabetes mellitus type 2Dig Dis Sci200853378578817846888
  • Fon TacerKRozmanDNonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulationJ Lipids2011201178397621773052
  • IizukaKHorikawaYChREBP: a glucose-activated transcription factor involved in the development of metabolic syndromeEndocr J200855461762418490833
  • NagleCAKlettELColemanRAHepatic triacylglycerol accumulation and insulin resistanceJ Lipid Res200950SupplS74S7918997164
  • Xue-junLiMeiXueShu-yuYanginventorThe First Affiliated Hospital of Xiamen University, assigneeA kind of berberine hydrochloride solid lipid nanoparticle pharmaceutics and its preparation methodChina PatentCN201210495674.4201336
  • CumminsCLJacobsenWChristiansUBenetLZCYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolamJ Pharmacol Exp Ther2004308114315514569063
  • TsaiPLTsaiTHHepatobiliary excretion of berberineDrug Metab Dispos200432440541215039293
  • XiaCQLiuNMiwaGTGanLSInteractions of cyclosporin a with breast cancer resistance proteinDrug Metab Dispos200735457658217220244
  • ShitaraYNagamatsuYWadaSSugiyamaYHorieTLong-lasting inhibition of the transporter-mediated hepatic uptake of sulfobromophthalein by cyclosporin a in ratsDrug Metab Dispos20093761172117819282398
  • LiuYZhangLSongHJiGUpdate on berberine in nonalcoholic fatty liver diseaseEvid Based Complement Alternat Med2013201330813423843872
  • LiYXuSMihaylovaMMAMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant miceCell Metab201113437638821459323
  • SunWBiYLiangHInhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic ratsEndocrine201139323524121088934
  • OsborneTFSterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin actionJ Biol Chem200027542323793238210934219
  • ShimanoHHortonJDShimomuraIHammerREBrownMSGoldsteinJLIsoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cellsJ Clin Invest19979958468549062341
  • JeongHWLeeJWKimWSA newly identified CG301269 improves lipid and glucose metabolism without body weight gain through activation of peroxisome proliferator-activated receptor alpha and gammaDiabetes201160249650621270261
  • XueMZhaoYLiXJComparison of toxicokinetic and tissue distribution of triptolide-loaded solid lipid nanoparticles vs free triptolide in ratsEur J Pharm Sci201247471371722677813
  • CalicetiCRizzoPCiceroAFPotential benefits of berberine in the management of perimenopausal syndromeOxid Med Cell Longev2015201572309325785174