Novel piperine-loaded Tween-integrated monoolein cubosomes as brain-targeted oral nanomedicine in Alzheimer’s disease: pharmaceutical, biological, and toxicological studies

References

• BrambillaDLe DroumaguetBNicolasJNanotechnologies for Alzheimer’s disease: diagnosis, therapy, and safety issuesNanomedicine20117552154021477665
   PubMed Web of Science ®Google Scholar
• QuerfurthHWLaFerlaFMAlzheimer’s diseaseN Engl J Med2010362432934420107219
   PubMed Web of Science ®Google Scholar
• PrinceMBryceRAlbaneseEWimoARibeiroWFerriCPThe global prevalence of dementia: a systematic review and metaanalysisAlzheimers Dement2013916375.e223305823
   PubMed Web of Science ®Google Scholar
• SahniJKDogguiSAliJBabootaSDaoLRamassamyCNeurotherapeutic applications of nanoparticles in Alzheimer’s diseaseJ Control Release2011152220823121134407
   PubMed Web of Science ®Google Scholar
• BullockRDengizACognitive performance in patients with Alzheimer’s disease receiving cholinesterase inhibitors for up to 5 yearsInt J Clin Pract200559781782215963209
   PubMed Web of Science ®Google Scholar
• FreagMSElnaggarYSAbdallahOYLyophilized phytosomal nanocarriers as platforms for enhanced diosmin delivery: optimization and ex vivo permeationInt J Nanomedicine201382385239723861584
   PubMed Web of Science ®Google Scholar
• PengSHungWLPengYSChuIMOligoalanine-modified Pluronic-F127 nanocarriers for the delivery of curcumin with enhanced entrapment efficiencyJ Biomater Sci Polym Ed201425121225123924930937
   PubMed Web of Science ®Google Scholar
• ChonpathompikunlertPWattanathornJMuchimapuraSPiperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer’s diseaseFood Chem Toxicol201048379880220034530
   PubMed Web of Science ®Google Scholar
• WuZ-JXiaX-JHuangX-SDetermination of equilibrium solubility and apparent oil/water partition coefficient of piperineJ Jinan Uni Natl Sci Med2012533473476
   Google Scholar
• SahuPKSharmaARayeesSPharmacokinetic study of piperine in Wistar rats after oral and intravenous administrationInt J Drug Deliv2014618288
   Google Scholar
• HashimotoKYaoiTKoshibaHPhotochemical isomerization of piperine, a pungent constituent in pepperFood Sci Technol Int1996212429
   Google Scholar
• PrabhakarKAfzalSMSurenderGKishanVTween 80 containing lipid nanoemulsions for delivery of indinavir to brainActa Pharma Sinica B201335345353
   Web of Science ®Google Scholar
• RaoZSiLGuanYPanHQiuJLiGInhibitive effect of cremophor RH40 or tween 80-based self-microemulsiflying drug delivery system on cytochrome P450 3A enzymes in murine hepatocytesJ Huazhong Univ Sci Technolog Med Sci201030556256821063835
   PubMedGoogle Scholar
• ElnaggarYSEl-MassikMAAbdallahOYSelf-nanoemulsifying drug delivery systems of tamoxifen citrate: design and optimizationInt J Pharm20093801–213314119635537
   PubMed Web of Science ®Google Scholar
• ElsheikhMAElnaggarYSGoharEYAbdallahOYNanoemulsion liquid preconcentrates for raloxifene hydrochloride: optimization and in vivo appraisalInt J Nanomedicine201273787380222888234
   PubMed Web of Science ®Google Scholar
• ElnaggarYSEl-MassikMAAbdallahOYSildenafil citrate nanoemulsion vs. self-nanoemulsifying delivery systems: rational development and transdermal permeationInt J Nanotechnol201188749763
   Web of Science ®Google Scholar
• ElnaggarYSEl-MassikMAAbdallahOYFabrication, appraisal, and transdermal permeation of sildenafil citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticlesInt J Nanomed2011631953205
   PubMed Web of Science ®Google Scholar
• ElnaggarYSEl-RefaieWMEl-MassikMAAbdallahOYLecithin-based nanostructured gels for skin delivery: an update on state of art and recent applicationsJ Control Release2014180102424531009
   PubMed Web of Science ®Google Scholar
• El-RefaieWMElnaggarYSEl-MassikMAAbdallahOYNovel self-assembled, gel-core hyaluosomes for non-invasive management of osteoarthritis: in-vitro optimization, ex-vivo and in-vivo permeationPharm Res20153292901291125777613
   PubMed Web of Science ®Google Scholar
• ElsheikhMAElnaggarYSAbdallahOYRationale employment of cell culture versus conventional techniques in pharmaceutical appraisal of nanocarriersJ Control Release20141949210225194779
   PubMed Web of Science ®Google Scholar
• FreagMSElnaggarAbdallahOYDevelopment of novel polymer-stabilized diosmin nanosuspensions: in vitro appraisal and ex vivo permeationInt J Pharm2013454146247123830765
   PubMedGoogle Scholar
• El-RefaieWMElnaggarYSEl-MassikMAAbdallahOYNovel curcumin-loaded gel-core hyaluosomes with promising burn-wound healing potential: development, in-vitro appraisal and in-vivo studiesInt J Pharm20154861–2889825818063
   PubMedGoogle Scholar
• YangDArmitageBMarderSRCubic liquid-crystalline nanoparticlesAngew Chem Int Ed Engl200443344402440915317018
   PubMed Web of Science ®Google Scholar
• WorleGDrechslerMKochMHSiekmannBWestesenKBunjesHInfluence of composition and preparation parameters on the properties of aqueous monoolein dispersionsInt J Pharm20073291–215015716987623
   PubMedGoogle Scholar
• LaiJLuYYinZHuFWuWPharmacokinetics and enhanced oral bioavailability in beagle dogs of cyclosporine A encapsulated in glyceryl monooleate/poloxamer 407 cubic nanoparticlesInt J Nanomedicine20105132320161984
   PubMed Web of Science ®Google Scholar
• GustafssonJLjusberg-WahrenHAlmgrenMLarssonKSubmicron particles of reversed lipid phases in water stabilized by a nonionic amphiphilic polymerLangmuir19971369646971
   Web of Science ®Google Scholar
• ChungHKimJUmJYKwonICJeongSYSelf-assembled “nano-cubicle” as a carrier for peroral insulin deliveryDiabetologia200245344845111914752
   PubMed Web of Science ®Google Scholar
• ZengNGaoXHuQLipid-based liquid crystalline nanoparticles as oral drug delivery vehicles for poorly water-soluble drugs: cellular interaction and in vivo absorptionInt J Nanomedicine201273703371822888230
   PubMed Web of Science ®Google Scholar
• D’HoogeRDe DeynPPApplications of the Morris water maze in the study of learning and memoryBrain Res Brain Res Rev2001361609011516773
   PubMedGoogle Scholar
• GangulyRGuhaDAlteration of brain monoamines & EEG wave pattern in rat model of Alzheimer’s disease and protection by Moringa oleiferaIndian J Med Res2008128674475119246799
   PubMed Web of Science ®Google Scholar
• Veerendra KumarMHGuptaYKIntracerebroventricular administration of colchicine produces cognitive impairment associated with oxidative stress in ratsPharmacol Biochem Behav200273356557112151031
   PubMed Web of Science ®Google Scholar
• MonleonSUrquizaACarmen ArenasMVinader-CaerolsCParraAChronic administration of fluoxetine impairs inhibitory avoidance in male but not female miceBehav Brain Res2002136248348812429411
   PubMed Web of Science ®Google Scholar
• WillsEDMechanisms of lipid peroxide formation in animal tissuesBiochem J19669936676765964963
   PubMed Web of Science ®Google Scholar
• KoracevicDKoracevicGDjordjevicVAndrejevicSCosicVMethod for the measurement of antioxidant activity in human fluidsJ Clin Pathol200154535636111328833
   PubMed Web of Science ®Google Scholar
• KonoYGeneration of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutaseArch Biochem Biophys1978186118919524422
   PubMed Web of Science ®Google Scholar
• EllmanGLCourtneyKDAndresVJrFeather-StoneRMA new and rapid colorimetric determination of acetylcholinesterase activityBiochem Pharmacol19617889513726518
   PubMed Web of Science ®Google Scholar
• ReitmanSFrankelSA colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminasesAm J Clin Pathol1957281566313458125
   PubMed Web of Science ®Google Scholar
• TabaccoAMeiattiniFModaETarliPSimplified enzymic/colorimetric serum urea nitrogen determinationClin Chem1979252336337759035
   PubMed Web of Science ®Google Scholar
• MurrayRLCreatinineKaplanAPeaceALClinical ChemistrySt Louis. Toronto. PrincetonThe C.V. Mosby Co198412611266
   Google Scholar
• Casciola-RosenLNicholsonDWChongTApopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic deathJ Exp Med19961835195719648642305
   PubMed Web of Science ®Google Scholar
• TiwariVChopraKResveratrol prevents alcohol-induced cognitive deficits and brain damage by blocking inflammatory signaling and cell death cascade in neonatal rat brainJ Neurochem2011117467869021375533
   PubMed Web of Science ®Google Scholar
• LowryOHRosebroughNJFarrALRandallRJProtein measurement with the Folin phenol reagentJ Biol Chem1951193126527514907713
   PubMed Web of Science ®Google Scholar
• ChanYHBiostatistics 102: quantitative data – parametric and non-parametric testsSingapore Med J200344839139614700417
   PubMedGoogle Scholar
• KotzSBalakrishnanNReadCBVidakovicBEncyclopedia of Statistical Sciences2Hobojen (NJ)John Wiley & Sons2006
   Google Scholar
• NasrMGhorabMKAbdelazemAIn vitro and in vivo evaluation of cubosomes containing 5-fluorouracil for liver targetingActa Pharma Sin B2015517988
   PubMed Web of Science ®Google Scholar
• MadheswaranTBaskaranRYongCSYooBKEnhanced topical delivery of finasteride using glyceryl monooleate-based liquid crystalline nanoparticles stabilized by cremophor surfactantsAAPS Pharm Sci Tech20141514451
   PubMed Web of Science ®Google Scholar
• BaskaranRMadheswaranTSundaramoorthyPKimHMYooBKEntrapment of curcumin into monoolein-based liquid crystalline nanoparticle dispersion for enhancement of stability and anticancer activityInt J Nanomedicine201493119313025061290
   PubMed Web of Science ®Google Scholar
• KulkarniSAFengSSEffects of particle size and surface modification on cellular uptake and biodistribution of polymeric nanoparticles for drug deliveryPharm Res201330102512252223314933
   PubMed Web of Science ®Google Scholar
• ZengNGaoXHuQLipid-based liquid crystalline nanoparticles as oral drug delivery vehicles for poorly water-soluble drugs: cellular interaction and in vivo absorptionInt J Nanomedicine201273703371822888230
   PubMed Web of Science ®Google Scholar
• LiSWangCWangMLiWMatsumotoKTangYAntidepressant like effects of piperine in chronic mild stress treated mice and its possible mechanismsLife Sci200780151373138117289085
   PubMed Web of Science ®Google Scholar
• D’HoogeRPeiYQRaesALebrunPvan BogaertPPde DeynPPAnticonvulsant activity of piperine on seizures induced by excitatory amino acid receptor agonistsArzneimittelforschung19964665575608767343
   PubMed Web of Science ®Google Scholar
• WattanathornJChonpathompikunlertPMuchimapuraSPripremATankamnerdthaiOPiperine, the potential functional food for mood and cognitive disordersFood Chem Toxicol20084693106311018639606
   PubMed Web of Science ®Google Scholar
• YusufMKhanMKhanRAAhmedBPreparation, characterization, in vivo and biochemical evaluation of brain targeted Piperine solid lipid nanoparticles in an experimentally induced Alzheimer’s disease modelJ Drug Target2013321300311
   Google Scholar
• VistisenBMuHHoyCELymphatic recovery of exogenous oleic acid in rats on long chain or specific structured triacylglycerol dietsLipids200641982783417152919
   PubMed Web of Science ®Google Scholar
• SaxenaVHussainMDPoloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancerInt J Nanomedicine2012771372122359450
   PubMed Web of Science ®Google Scholar
• NavarroVJSeniorJRDrug-related hepatotoxicityN Engl J Med2006354773173916481640
   PubMed Web of Science ®Google Scholar
• SinghABhatTKSharmaOPClinical biochemistry of hepatotoxicityJ Clin Toxicol2011
   PubMedGoogle Scholar
• Susan EmeighHLewisBKAssessing Renal Effects of Toxicants In Vivo, in Toxicology of the Kidney, 3rd edInforma Healthcare200481147
   Google Scholar
• RachedEHoffmannDBlumbachKWeberKDekantWMallyAEvaluation of putative biomarkers of nephrotoxicity after exposure to ochratoxin a in vivo and in vitroToxicol Sci2008103237138118308701
   PubMed Web of Science ®Google Scholar
• YildirimerLThanhNTLoizidouMSeifalianAMToxicology and clinical potential of nanoparticlesNano Today20116658560723293661
   PubMedGoogle Scholar
• OberdorsterGElderARinderknechtANanoparticles and the brain: cause for concern?J Nanosci Nanotechnol2009984996500719928180
   PubMed Web of Science ®Google Scholar
• TricklerWJLantzSMMurdockRCSilver nanoparticle induced blood-brain barrier inflammation and increased permeability in primary rat brain microvessel endothelial cellsToxicol Sci2010118116017020713472
   PubMed Web of Science ®Google Scholar
• LiuZGastardMVerinaTBoraSMoutonPRKoliatsosVEEstrogens modulate experimentally induced apoptosis of granule cells in the adult hippocampusJ Comp Neurol200144111811745631
   PubMed Web of Science ®Google Scholar
• KumarASeghalNPadiSVNaiduPSDifferential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in ratsEur J Pharmacol20065511586617027965
   PubMed Web of Science ®Google Scholar
• ElnaggarYSREtmanSMAbdelmonsifDAAbdallahOYOptimization and in-vivo appraisal of piperine-loaded intranasal chitosan nanoparticles as brain-targeted dual acting therapy in Alzheimer’s diseaseJournal of Pharmaceutical Sciences Available: http://www.researchgate.net/publication/279446825_Optimization_and_In-vivo_Appraisal_of_Piperine-loaded_Intranasal_Chitosan_Nanoparticles_as_Brain-Targeted_Dual_Acting_Therapy_in_Alzheimer’s_diseaseAccessed July 3, 2015
   Google Scholar