169
Views
6
CrossRef citations to date
0
Altmetric
Original Research

Timing of initiation of low-molecular-weight heparin administration in pregnant women with antiphospholipid syndrome: a randomized clinical trial of efficacy and safety

, , , , , , , , , & show all
Pages 41-47 | Published online: 14 Jan 2019

References

  • LevineJSBranchDWRauchJThe antiphospholipid syndromeN Engl J Med20023461075276311882732
  • RoubeyRAImmunology of the antiphospholipid antibody syndromeArthritis Rheum1996399144414548814055
  • Alijotas-ReigJVilardell-TarresMIs obstetric antiphospholipid syndrome a primary nonthrombotic, proinflammatory, complement-mediated disorder related to antiphospholipid antibodies?Obstet Gynecol Surv2010651394520040128
  • MeroniPLRaschiECameraMEndothelial activation by aPL: a potential pathogenetic mechanism for the clinical manifestations of the syndromeJ Autoimmun200015223724010968917
  • EmpsonMLassereMCraigJScottJPrevention of recurrent miscarriage for women with antiphospholipid antibody or lupus anticoagulantCochrane Database Syst Rev20052CD002859
  • NobleLSKuttehWHLasheyNFranklinRDHerradaJAntiphospholipid antibodies associated with recurrent pregnancy loss: prospective, multicenter, controlled pilot study comparing treatment with low-molecular-weight heparin versus unfractionated heparinFertil Steril200583368469015749498
  • StephensonMDBallemPJTsangPTreatment of antiphospholipid antibody syndrome (APS) in pregnancy: a randomized pilot trial comparing low molecular weight heparin to unfractionated heparinJ Obstet Gynaecol Can200426872973415307977
  • MartelNLeeJWellsPSRisk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysisBlood200510682710271515985543
  • PettiläVLeinonenPMarkkolaAHiilesmaaVKaajaRPostpartum bone mineral density in women treated for thromboprophylaxis with unfractionated heparin or LMW heparinThromb Haemost200287218218611858475
  • RaiRCohenHDaveMReganLRandomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)BMJ199731470762532579022487
  • GuerinJShengYReddelSIversonGMChapmanMGKrilisSAHeparin inhibits the binding of beta 2-glycoprotein I to phospholipids and promotes the plasmin-mediated inactivation of this blood protein. Elucidation of the consequences of the two biological events in patients with the anti-phospholipid syndromeJ Biol Chem200227742644264911711550
  • BosePBlackSKadyrovMHeparin and aspirin attenuate placental apoptosis in vitro: implications for early pregnancy failureAm J Obstet Gynecol20051921233015671997
  • GirardiGRedechaPSalmonJEHeparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activationNat Med200410111222122615489858
  • BermanJGirardiGSalmonJETNF-alpha is a critical effector and a target for therapy in antiphospholipid antibody-induced pregnancy lossJ Immunol2005174148549015611274
  • Di SimoneNDi NicuoloFSanguinettiMLow-molecular weight heparin induces in vitro trophoblast invasiveness: role of matrix metal-loproteinases and tissue inhibitorsPlacenta200728429830416750851
  • MiyakisSLockshinMDAtsumiTInternational consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)J Thromb Haemost20064229530616420554
  • FarquharsonRGQuenbySGreavesMAntiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatmentObstet Gynecol2002100340841312220757
  • MarchettiTCohenMde MoerloosePObstetrical antiphospholipid syndrome: from the pathogenesis to the clinical and therapeutic implicationsClin Dev Immunol20132013819
  • SimioniPSansonBJPrandoniPIncidence of venous thrombo-embolism in families with inherited thrombophiliaThromb Haemost199981219820210063991
  • SalmonJEGirardiGThe role of complement in the antiphospholipid syndromeCurr Dir Autoimmun2004713314814719378
  • OpatrnyLDavidMKahnSRShrierIReyEAssociation between antiphospholipid antibodies and recurrent fetal loss in women without autoimmune disease: a metaanalysisJ Rheumatol200633112214222117014001
  • IsmailAMHamedAHSasoSAbu-ElhasanAMAbu-ElgharMMAbdelmegedANRandomized controlled study of pre-conception thromboprophylaxis among patients with recurrent spontaneous abortion related to antiphospholipid syndromeInt J Gynaecol Obstet2016132221922326810338
  • KeelingDMackieIMooreGWGreerIAGreavesMBritish Committee for Standards in HaematologyGuidelines on the investigation and management of antiphospholipid syndromeBr J Haematol20121571475822313321
  • FishmanPFalach-VakninESredniBAspirin-interleukin-3 interrelationships in patients with anti-phospholipid syndromeAm J Reprod Immunol199635280848839134