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Review

Vaginal rings for delivery of HIV microbicides

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Pages 595-605 | Published online: 20 Nov 2012

References

  • FolkmanJLongDMJrRosenbaumRSilicone rubber: a new diffusion property useful for general anesthesiaScience196615437451481495922861
  • FolkmanJLongDMThe use of silicone rubber as a carrier for prolonged drug therapyJ Surg Res19644313914214130164
  • DziukPJCookBPassage of steroids through silicone rubberEndocrinology19667812082115948426
  • DuncanGWThe Upjohn CompanyMedicated devices and methodsUnited States patentUS 35454391281970
  • HoffmanASThe origins and evolution of “controlled” drug delivery systemsJ Control Release2008132315316318817820
  • GuptaKMPearceSMPoursaidAEPolyurethane intravaginal ring for controlled delivery of dapivirine, a nonnucleoside reverse transcriptase inhibitor of HIV-1J Pharm Sci200897104228423918338805
  • JohnsonTGuptaKFabianJAlbrightTKiserPSegmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovirEur J Pharm Sci201039420321219958831
  • ClarkMRKiserPFLoxleyAMcConvilleCMalcolmRKFriendDRPharmacokinetics of UC781-loaded intravaginal ring segments in rabbits: a comparison of polymer matricesDrug Deliv Transl Res201113238246
  • KaurMGuptaKMPoursaidAEEngineering a degradable polyurethane intravaginal ring for sustained delivery of dapivirineDrug Delivery Trans Res201113223237
  • ColasACurtisJSilicone biomaterials: history and chemistryBiomaterials Science: An Introduction to Materials in Medicine2nd edElsevierAcademic Press20048085
  • CurtisJColasAMedical applications of siliconesRatnerBDHoffmanASSchoenFJLemonsJEBiomaterials Science: An Introduction to Materials in Medicine2nd edElsevierAcademic Press2004698707
  • Al-AzzawiFBucklerHMfor the United Kingdom Vaginal Ring Investigator GroupComparison of a novel vaginal ring delivering estradiol acetate versus oral estradiol for relief of vasomotor menopausal symptomsClimacteric20036211812712841882
  • BarentsenRvandeWeijerPHMSchramJHNContinuous low dose estradiol released from a vaginal ring versus estriol vaginal cream for urogenital atrophyEur J Obstet Gynecol Reprod Biol199771173809031963
  • BucklerHAl-AzzawiFfor the UK VR Multicentre Trial GroupThe effect of a novel vaginal ring delivering oestradiol acetate on climacteric symptoms in postmenopausal womenBrit J Obstet Gynecol20031108753759
  • SperoffLEfficacy and tolerability of a novel estradiol vaginal ring for relief of menopausal symptomsObstet Gynecol2003102482383414551014
  • CroxattoHBBracheVMassaiRFeasibility study of Nestorone-ethinylestradiol vaginal contraceptive ring for emergency contraceptionContraception2006731465216371294
  • KumarNKoideSSTsongYSundaramKNestorone: a progestin with a unique pharmacological profileSteroids20006510–1162963611108869
  • FraserISWeisbergEBracheVSerum Nestorone and ethinyl estradiol levels, and ovulation inhibition in women using three different dosage combinations of a Nestorone progestogen-ethinyl estradiol contraceptive vaginal ring on a bleeding-signaled regimenContraception2005721404515964291
  • SivinIMishellDRJrAlvarezFContraceptive vaginal rings releasing Nestorone and ethinylestradiol: a 1-year dose-finding trialContraception200571212212915707562
  • MalcolmKWoolfsonDRussellJAndrewsCIn vitro release of nonoxynol-9 from silicone matrix intravaginal ringsJ Control Release200391335536412932713
  • Van DammeLRamgeeGAlvaryMEffectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trialLancet2002360933897197712383665
  • RoddyREZekengLRyanKA controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseasesN Engl J Med19983395045109709043
  • MalcolmRKWoolfsonADTonerCFLong-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal ringsJ Antimicrob Chemother200556595495616155060
  • RomanoJVarianoBCoplanPVan RoeyJDouvilleKRosenbergZSafety and availability of dapivirine (TMC120) delivered from an intravaginal ringAIDS Res Hum Retroviruses200925548348819388819
  • NelASmytheSYoungKSafety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative womenJ Acquir Immune Defic Syndr200951441642319623693
  • Di FabioSVan RoeyJGianniniGInhibition of vaginal transmission of HIV-1 in hu-SCID mice by the non-nucleoside reverse transcriptase inhibitor TMC120 in a gel formulationAIDS200317111597160412853741
  • HerrewegeYVMichielsJVan RoeyJIn vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicidesAntimicrob Agents Chemother200448133733914693562
  • WoolfsonADElliottGRGilliganCAPassmoreCMDesign of an intravaginal ring for the controlled delivery of 17 beta-estradiol as its 3-acetate esterJ Control Release199961331932810477804
  • WoolfsonADMalcolmRKGallagherRJDesign of a silicone reservoir intravaginal ring for the delivery of oxybutyninJ Control Release200391346547612932723
  • WoolfsonADMalcolmRKGormanSPJonesDSBrownAFMcCullaghSDSelf-lubricating silicone elastomer biomaterialsJ Mater Chem2003131024652470
  • MalcolmRKMcCullaghSDWoolfsonADGormanSPJonesDSCuddyJControlled release of a model antibacterial drug from a novel self-lubricating silicone biomaterialJ Control Release200497231332015196758
  • Promadej-LanierNSmithJSrinivasanPDevelopment and evaluation of a vaginal ring device for sustained delivery of HIV microbicides to non-human primatesJ Med Primatol200938426327119476564
  • FetherstonSGeerLVeazeyRSPartial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220J Antimicrob Chemother
  • MalcolmRKVeazeyRSGeerLSustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaquesAntimicrob Agents Chemother201256522522258
  • SulakPJSmithVCoffeeAFrequency and management of breakthrough bleeding with continuous use of the transvaginal contraceptive ring: a randomized controlled trialObstets Gynecol20081123563571
  • LoxleyAMitchnickMOkohOEthylene vinyl acetate intravaginal rings for the simultaneous delivery of the antiretroviral UC781 and contraceptive levonorgestrelDrug Delivery Trans Res201113247255
  • ClarkMRJohnsonTJMcCabeRTA hot-melt extruded intravaginal ring for the sustained delivery of the antiretroviral microbicide UC781J Pharm Sci2012101257658721976110
  • BaumMMButkyavicheneIGilmanJAn intravaginal ring for the simultaneous delivery of multiple drugsJ Pharm Sci201210182833284322619076
  • KellerMJMaloneAMCarpenterCASafety and pharmacokinetics of aciclovir in women following release from a silicone elastomer vaginal ringJ Antimicrob Chemother20126782005201222556381
  • MossJAMaloneAMSmithTJSimultaneous delivery of tenofovir and acyclovir via an intravaginal ringAntimicrob Agents Chemother201256287588222123689
  • MorrowRJWoolfsonADDonnellyLSustained release of proteins from a modified vaginal ring deviceEur J Pharm Biopharm201177131021055465
  • WoolfsonADUmrethiaMLKettVLFreeze-dried, mucoadhesive system for vaginal delivery of the HIV microbicide, dapivirine: optimisation by an artificial neural networkInt J Pharm201038813614320045043
  • VartiainenJWahlströmTNilssonCGEffects and acceptability of a new 17 beta-oestradiol-releasing vaginal ring in the treatment of postmenopausal complaintsMaturitas19931721291378231904
  • HanYASinghMSaxenaBBDevelopment of vaginal rings for sustained release of nonhormonal contraceptives and anti-HIV agentsContraception200776213213817656183
  • SaxenaBHanYFuDSustained release of microbicides by newly engineered vaginal ringsAIDS200923891792219381077
  • YangCCMaravillaKRKilbourne-BrookMAustinGMagnetic resonance imaging of SILCS diaphragm: anatomical considerations and corroboration with clinical fitContraception200776323824417707723
  • CoffeyPSKilbourne-BrookMBracheVCochónLComparative acceptability of the SILCS and Ortho ALL-FLEX® diaphragms among couples in the Dominican RepublicContraception200878541842318929740
  • CoffeyPSKilbourne-BrookMWear and care of the SILCS diaphragm: experience from three countriesSex Health20107215916420465980
  • CoffeyPSKilbourne-BrookMBeksinskaMThongkrajaiEShort-term acceptability of a single-size diaphragm among couples in South Africa and ThailandJ Fam Plann Reprod Health Care200834423323618854068
  • SchwartzJLBallaghSACreininMDSILCS diaphragm: postcoital testing of a new single-size contraceptive deviceContraception200878323724418692615
  • MoenchTRChipatoTPadianNSPreventing disease by protecting the cervix: the unexplored promise of internal vaginal barrier devicesAIDS200115131595160211546933
  • FriendDIntravaginal rings: controlled release systems for contraception and prevention of transmission of sexually transmitted infectionsDrug Deliv Transl Res201113185193
  • FriendDDoncelGCombining prevention of HIV-1, other sexually transmitted infections and unintended pregnancies: development of dual-protection technologiesAntiviral Res201088Suppl 1S47S5421109068
  • ThurmanARClarkMRDoncelGFMultipurpose prevention technologies: biomedical tools to prevent HIV-1, HSV-2, and unintended pregnanciesInfect Dis Obstet Gynecol Epub 2011 Aug 9
  • MajorILowryDMalcolmKDevelopment of a microbicide-releasing diaphragm as an HIV prevention strategyConf Proc IEEE Eng Biol Soc201010891092
  • MajorIBoydPKilbourne-BrookMA modified SILCS contraceptive diaphragm for long-term controlled release of the HIV microbicide dapivirineContraception
  • MalcolmRKEdwardsKLKiserPRomanoJSmithTJAdvances in microbicide vaginal ringsAntiviral Res201088Suppl 1S30S3921109066
  • AravantinouMSingerRDerbyNThe nonnucleoside reverse transcription inhibitor MIV-160 delivered from an intravaginal ring, but not from a carrageenan gel, protects against simian/human immunodeficiency virus-RT infectionAIDS Res Human Retrovir2012In press