Dyslipidemia in women: etiology and management

References

• KochanekKDXuJQMurphySLMiniñoAMKungHCDeaths: final data for 2009Natl Vital Stat Rep2011603
   Google Scholar
• RogerVLGoASLloyd-JonesDMHeart disease and stroke statistics – 2011 update. A report from the American Heart AssociationCirculation20111234e18e20921160056
   PubMed Web of Science ®Google Scholar
• LernerDJKannelWBPatterns of coronary heart disease morbidity and mortality in the sexes: a 26-year follow-up of the Framingham populationAm Heart J198611123833903946178
   PubMed Web of Science ®Google Scholar
• KeysAMenottiAAravanisCThe seven countries study: 2,289 deaths in 15 yearsPrev Med19841321411546739443
   PubMed Web of Science ®Google Scholar
• KannelWBCastelliWPGordonTCholesterol in the prediction of atherosclerotic diseaseAnn Intern Med197990185217290
   PubMed Web of Science ®Google Scholar
• SemposCTCleemanJICarrollMDPrevalence of high blood cholesterol among US adults: an update based on guidelines from the Second Report of the National Cholesterol Education Program Adult Treatment PanelJAMA199326923300930148501843
   PubMed Web of Science ®Google Scholar
• MostaghelEWatersDWomen do benefit from lipid lowering: latest clinical trial dataCardiol Rev200311141212493130
   PubMedGoogle Scholar
• [No authors listed]Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final reportCirculation2002106253143342112485966
   PubMed Web of Science ®Google Scholar
• GenestJMcPhersonRFrohlichJ2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult – 2009 recommendationsCan J Cardiol2009251056757919812802
   PubMed Web of Science ®Google Scholar
• European Association for Cardiovascular Prevention and RehabilitationReinerZCatapanoALDe BackerGESC Committee for Practice Guidelines (CPG) 2008–2010 and 2010–2012 CommitteesESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)Eur Heart J201132141769181821712404
   PubMed Web of Science ®Google Scholar
• ClarkeRPedenJFHopewellJCGenetic variants associated with Lp(a) lipoprotein level and coronary diseaseN Engl J Med2009361262518252820032323
   PubMed Web of Science ®Google Scholar
• Emerging Risk Factors CollaborationErqouSKaptogeSPerryPLLipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortalityJAMA2009302441242319622820
   PubMed Web of Science ®Google Scholar
• BaysHETothPPKris-EthertonPMObesity, adiposity, and dyslipidemia: a consensus statement from the National Lipid AssociationJ Clin Lipidol20137430438323890517
   PubMed Web of Science ®Google Scholar
• KnoppRHCardiovascular effects of endogenous and exogenous sex hormones over a woman’s lifetimeAm J Obstet Gynecol19881586 Pt 2163016433287934
   PubMed Web of Science ®Google Scholar
• BittnerVLipoprotein abnormalities related to women’s healthAm J Cardiol2002908A77i84i12088789
   PubMed Web of Science ®Google Scholar
• LloydJKHyperlipidaemia in childrenBr Heart J1975372105114164201
   PubMedGoogle Scholar
• FreedmanDSBowmanBAOtvosJDSrinivasanSRBerensonGSLevels and correlates of LDL and VLDL particle sizes among children: the Bogalusa Heart StudyAtherosclerosis2000152244144910998473
   PubMed Web of Science ®Google Scholar
• KreisbergRAKasimSCholesterol metabolism and agingAm J Med1987821B54603544833
   PubMed Web of Science ®Google Scholar
• FreedmanDSBowmanBASrinivasanSRBerensonGSOtvosJDDistribution and correlates of high-density lipoprotein subclasses among children and adolescentsMetabolism200150337037611230794
   PubMed Web of Science ®Google Scholar
• DesoyeGSchweditschMOPfeifferKPZechnerRKostnerGMCorrelation of hormones with lipid and lipoprotein levels during normal pregnancy and postpartumJ Clin Endocrinol Metab19876447047123546352
   PubMed Web of Science ®Google Scholar
• LippiGAlbieroAMontagnanaMLipid and lipoprotein profile in physiological pregnancyClin Lab2007533–417317717447654
   PubMed Web of Science ®Google Scholar
• MazurkiewiczJCWattsGFWarburtonFGSlavinBMLowyCKoukkouESerum lipids, lipoproteins and apolipoproteins in pregnant non-diabetic patientsJ Clin Pathol19944787287317962626
   PubMed Web of Science ®Google Scholar
• Van StiphoutWAHofmanAde BruijnAMSerum lipids in young women before, during, and after pregnancyAm J Epidemiol198712659229283661539
   PubMed Web of Science ®Google Scholar
• LewisCEFunkhouserERaczynskiJMSidneySBildDEHowardBVAdverse effect of pregnancy on high density lipoprotein (HDL) cholesterol in young adult women: the CARDIA studyAm J Epidemiol199614432472548686693
   PubMed Web of Science ®Google Scholar
• ZechnerRDesoyeGSchweditschMOPfeifferKPKostnerGMFluctuations of plasma lipoprotein-A concentrations during pregnancy and post partumMetabolism19863543333362937991
   PubMed Web of Science ®Google Scholar
• Bonithon-KoppCScarabinP-YDarneBMalmejacAGuizeLMenopause-related changes in lipoproteins and some other cardiovascular risk factorsInt J Epidemiol199019142482351523
   PubMed Web of Science ®Google Scholar
• WuZWuXZhangYRelationship of menopausal status and sex hormones to serum lipids and blood pressureInt J Epidemiol19901922973022376439
   PubMed Web of Science ®Google Scholar
• AkahoshiMSodaMNakashimaEShimaokaKSetoSYanoKEffects of menopause on trends of serum cholesterol, blood pressure, and body mass indexCirculation199694161668964119
   PubMed Web of Science ®Google Scholar
• HjortlandMCMcNamaraPMKannelWBSome atherogenic concomitants of menopause: the Framingham studyAm J Epidemiol197610333043111258858
   PubMed Web of Science ®Google Scholar
• CarrMCKimKHZambonAChanges in LDL density across the menopausal transitionJ Investig Med Off Publ Am Fed Clin Res2000484245250
   Google Scholar
• MatthewsKAMeilahnEKullerLHKelseySFCaggiulaAWWingRRMenopause and risk factors for coronary heart diseaseN Engl J Med1989321106416462488072
   PubMed Web of Science ®Google Scholar
• LipGYBlannADJonesAFBeeversDGEffects of hormone-replacement therapy on hemostatic factors, lipid factors, and endothelial function in women undergoing surgical menopause: implications for prevention of atherosclerosisAm Heart J199713447647719351746
   PubMed Web of Science ®Google Scholar
• JennerJLOrdovasJMLamon-FavaSEffects of age, sex, and menopausal status on plasma lipoprotein(a) levels. The Framingham Offspring StudyCirculation1993874113511418462142
   PubMed Web of Science ®Google Scholar
• HammanRFBennettPHMillerMThe effect of menopause on serum cholesterol in American (Pima) Indian WomenAm J Epidemiol197510221641691080357
   PubMed Web of Science ®Google Scholar
• FotherbyKOral contraceptives and lipidsBMJ19892986680104910502497884
   PubMed Web of Science ®Google Scholar
• TikkanenMJNikkiläEAKuusiTSipinenSHigh density lipoprotein-2 and hepatic lipase: reciprocal changes produced by estrogen and norgestrelJ Clin Endocrinol Metab1982546111311177076794
   PubMed Web of Science ®Google Scholar
• RealiniJPGoldzieherJWOral contraceptives and cardiovascular disease: a critique of the epidemiologic studiesAm J Obstet Gynecol19851526 Pt 27297983895946
   PubMed Web of Science ®Google Scholar
• LewisMAMyocardial infarction and stroke in young women: what is the impact of oral contraceptives?Am J Obstet Gynecol19981793 Pt 2S68S779753313
   PubMed Web of Science ®Google Scholar
• CauleyJALaPorteREKullerLHBatesMSandlerRBMenopausal estrogen use, high density lipoprotein cholesterol subfractions and liver functionAtherosclerosis198349131396651911
   PubMed Web of Science ®Google Scholar
• MeadeTWRandomised comparison of oestrogen versus oestrogen plus progestogen hormone replacement therapy in women with hysterectomyBMJ199631270294734788597678
   PubMedGoogle Scholar
• WakatsukiAIkenoueNOkataniYFukayaTEstrogen-induced small low density lipoprotein particles may be atherogenic in postmenopausal womenJ Am Coll Cardiol200137242543011216957
   PubMed Web of Science ®Google Scholar
• SomaMFumagalliRPaolettiRPlasma Lp(a) concentration after oestrogen and progestagen in postmenopausal womenLancet199133787416121671962
   PubMed Web of Science ®Google Scholar
• EdmundsELipGYHCardiovascular risk in women: the cardiologist’s perspectiveQJM200093313514510751232
   PubMed Web of Science ®Google Scholar
• GrodsteinFStampferMJColditzGAPostmenopausal hormone therapy and mortalityN Engl J Med199733625176917759187066
   PubMed Web of Science ®Google Scholar
• BushTLBarrett-ConnorECowanLDCardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program Follow-up StudyCirculation1987756110211093568321
   PubMed Web of Science ®Google Scholar
• GradyDRubinSMPetittiDBHormone therapy to prevent disease and prolong life in postmenopausal womenAnn Intern Med199211712101610371443971
   PubMed Web of Science ®Google Scholar
• HulleySGradyDBushTRandomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research GroupJAMA199828076056139718051
   PubMed Web of Science ®Google Scholar
• AndersonGLLimacherMAssafAREffects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women’s Health Initiative randomized controlled trialJAMA2004291141701171215082697
   PubMed Web of Science ®Google Scholar
• MoscaLAppelLJBenjaminEJEvidence-based guidelines for cardiovascular disease prevention in womenJ Am Coll Cardiol200443590092114998635
   PubMed Web of Science ®Google Scholar
• The Emerging Risk Factors CollaborationMajor lipids, apolipoproteins, and risk of vascular diseaseJAMA2009302181993200019903920
   PubMed Web of Science ®Google Scholar
• BassKMNewschafferCJKlagMJBushTLPlasma lipoprotein levels as predictors of cardiovascular death in womenArch Intern Med199315319220922168215724
   PubMedGoogle Scholar
• HokansonJEAustinMAPlasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studiesJ Cardiovasc Risk1996322132198836866
   PubMedGoogle Scholar
• KamigakiASSiscovickDSSchwartzSMLow density lipoprotein particle size and risk of early-onset myocardial infarction in womenAm J Epidemiol20011531093994511384949
   PubMed Web of Science ®Google Scholar
• ShlipakMGSimonJAVittinghoffEEstrogen and progestin, lipoprotein(a), and the risk of recurrent coronary heart disease events after menopauseJAMA2000283141845185210770146
   PubMed Web of Science ®Google Scholar
• OrnishDScherwitzLWBillingsJHIntensive lifestyle changes for reversal of coronary heart diseaseJAMA199828023200120079863851
   PubMed Web of Science ®Google Scholar
• EstruchRRosESalas-SalvadóJPrimary prevention of cardiovascular disease with a Mediterranean dietN Engl J Med2013368141279129023432189
   PubMed Web of Science ®Google Scholar
• HowardBVVan HornLHsiaJLow-fat dietary pattern and risk of cardiovascular disease: the Women’s Health Initiative Randomized Controlled Dietary Modification TrialJAMA2006295665566616467234
   PubMed Web of Science ®Google Scholar
• KasteleinJJPAkdimFStroesESGSimvastatin with or without ezetimibe in familial hypercholesterolemiaN Engl J Med2008358141431144318376000
   PubMed Web of Science ®Google Scholar
• ShepherdJCobbeSMFordIPrevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study GroupN Engl J Med199533320130113077566020
   PubMed Web of Science ®Google Scholar
• SacksFMPfefferMAMoyeLAThe effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigatorsN Engl J Med199633514100110098801446
   PubMed Web of Science ®Google Scholar
• DownsJRClearfieldMWeisSPrimary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPSJAMA199827920161516229613910
   PubMed Web of Science ®Google Scholar
• [No authors listed]Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)Lancet19943448934138313897968073
   PubMed Web of Science ®Google Scholar
• [No authors listed]MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trialLancet2002360932672212114036
   PubMed Web of Science ®Google Scholar
• LIPID Study Group (Long-term Intervention with Pravastatin in Ischaemic Disease)Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: the LIPID trial follow-upLancet200235993151379138711978335
   PubMed Web of Science ®Google Scholar
• LaRosaJCGrundySMWatersDDIntensive lipid lowering with atorvastatin in patients with stable coronary diseaseN Engl J Med2005352141425143515755765
   PubMed Web of Science ®Google Scholar
• CannonCPBraunwaldEMcCabeCHIntensive versus moderate lipid lowering with statins after acute coronary syndromesN Engl J Med2004350151495150415007110
   PubMed Web of Science ®Google Scholar
• CannonCPSteinbergBAMurphySAMegaJLBraunwaldEMeta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapyJ Am Coll Cardiol200648343844516875966
   PubMed Web of Science ®Google Scholar
• FrickMHEloOHaapaKHelsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart diseaseN Engl J Med198731720123712453313041
   PubMed Web of Science ®Google Scholar
• LaRosaJCHeJVupputuriSEffect of statins on risk of coronary disease: a meta-analysis of randomized controlled trialsJAMA1999282242340234610612322
   PubMed Web of Science ®Google Scholar
• WalsJEPignoneMDrug treatment of hyperlipidemia in womenJAMA2004291182243225215138247
   PubMed Web of Science ®Google Scholar
• MoraSGlynnRJHsiaJMacFadyenJGGenestJRidkerPMStatins for the primary prevention of cardiovascular events in women with elevated high-sensitivity C-reactive protein or dyslipidemia: results from the Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) and meta-analysis of women from primary prevention trialsCirculation201012191069107720176986
   PubMed Web of Science ®Google Scholar
• RobinsSJRelation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trialJAMA2001285121585159111268266
   PubMed Web of Science ®Google Scholar
• BaigentCKeechAKearneyPMEfficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statinsLancet200536694931267127816214597
   PubMed Web of Science ®Google Scholar
• ACCORD Study GroupGinsbergHNElamMBEffects of combination lipid therapy in type 2 diabetes mellitusN Engl J Med2010362171563157420228404
   PubMed Web of Science ®Google Scholar
• BodenWEProbstfieldJLAndersonTNiacin in patients with low HDL cholesterol levels receiving intensive statin therapyN Engl J Med2011365242255226722085343
   PubMed Web of Science ®Google Scholar
• HPS2-THRIVE Collaborative GroupHPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatmentEur Heart J201334171279129123444397
   PubMed Web of Science ®Google Scholar
• The Lipid Research Clinics Coronary Primary Prevention Trial results I Reduction in incidence of coronary heart diseaseJAMA198425133513646361299
   PubMed Web of Science ®Google Scholar
• CannonCPGiuglianoRPBlazingMARationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromesAm Heart J2008156582683219061694
   PubMed Web of Science ®Google Scholar
• BaigentCLandrayMJReithCThe effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trialLancet201137797842181219221663949
   PubMed Web of Science ®Google Scholar
• JonesPHDavidsonMHReporting rate of rhabdomyolysis with fenofibrate + statin versus gemfibrozil + any statinAm J Cardiol200595112012215619408
   PubMed Web of Science ®Google Scholar
• PrueksaritanontTZhaoJJMaBMechanistic studies on metabolic interactions between gemfibrozil and statinsJ Pharmacol Exp Ther200230131042105112023536
   PubMed Web of Science ®Google Scholar
• PrueksaritanontTSubramanianRFangXGlucuronidation of statins in animals and humans: a novel mechanism of statin lactonizationDrug Metab Dispos Biol Fate Chem200230550551211950779
   PubMed Web of Science ®Google Scholar
• StoneNJRobinsonJLichtensteinAH2013ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Practice GuidelinesCirculation11122013 [Epub ahead of print.]
   Google Scholar
• GoffDCJrLloyd-JonesDMBennettG2013ACC/AHA Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice GuidelinesCirculation11122013 [Epub ahead of print.]
   Google Scholar
• DownsJRClearfieldMWeisSPrimary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention StudyJAMA1998279161516229613910
   PubMed Web of Science ®Google Scholar
• Scandinavian Simvastatin Survival Study GroupRandomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)Lancet1994344138313897968073
   PubMed Web of Science ®Google Scholar
• SacksFMPfefferMAMoyeLAThe effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigatorsN Engl J Med1996335100110098801446
   PubMed Web of Science ®Google Scholar
• Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol LevelsN Engl J Med1998339134913579841303
   PubMed Web of Science ®Google Scholar
• Heart Protection Study Collaborative GroupMRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebo controlled trialLancet200236072212114036
   PubMed Web of Science ®Google Scholar