References
- HandAPolyuria and tuberculosisArch Pediatr189310673675
- RollinsBJGenomic alterations in Langerhans cell histiocytosisHematol Oncol Clin North Am201529583985126461146
- KompDMHistorical perspectives of Langerhans cell histiocytosisHematol Oncol Clin North Am1987119213312151
- KompDMTherapeutic strategies for Langerhans cell histiocytosisJ Pediatr199111922742751861214
- LadischSHistiocytosisWilloughbyMLSiegelSEButterworth’s International Medical Reviews: Pediatrics1London, UKButterworth Scientific198295109
- EgelerRMAnnelsNEHogendoornPCLangerhans cell histiocytosis: a pathologic combination of oncogenesis and immune dysregulationPediatr Blood Cancer200442540140315049009
- FadeelBHenterJILangerhans-cell histiocytosis: neoplasia or unbridled inflammation?Trends Immunol2003248409410 author reply 410–41112909451
- LichtensteinLHistiocytosis X; integration of eosinophilic granuloma of bone, Letterer-Siwe disease, and Schuller-Christian disease as related manifestations of a single nosologic entityAMA Arch Pathol19535618410213057466
- NezelofCBassetFRousseauMFHistiocytosis X histogenetic arguments for a Langerhans cell originBiomedicine19731853653714356601
- Histiocytosis syndromes in children. Writing Group of the Histiocyte SocietyLancet1987185262082092880029
- FavaraBEFellerACPauliMContemporary classification of histiocytic disorders. The WHO Committee on histiocytic/reticulum cell proliferations. Reclassification Working Group of the Histiocyte SocietyMed Pediatr Oncol19972931571669212839
- ChuTJaffeRThe normal Langerhans cell and the LCH cellBr J Cancer Suppl199423S4S107521202
- CouryFAnnelsNRivollierALangerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusionNat Med2008141818718157139
- IkawaYNishimuraRArakiRPathognomonic serum cytokine profiles identify life-threatening langerhans cell histiocytosisBr J Haematol Epub472016
- KannourakisGAbbasAThe role of cytokines in the pathogenesis of Langerhans cell histiocytosisBr J Cancer Suppl199423S37S408075004
- EgelerRMFavaraBEvan MeursMLamanJDClaassenEDifferential in situ cytokine profiles of Langerhans-like cells and T cells in Langerhans cell histiocytosis: abundant expression of cytokines relevant to disease and treatmentBlood199994124195420110590064
- RossoDAKarisJBraierJLHenterJIFadeelBElevated serum levels of the decoy receptor osteoprotegerin in children with langerhans cell histiocytosisPediatr Res200659228128616439593
- RossoDARipoliMFRoyADiezRAZelazkoMEBraierJLSerum levels of interleukin-1 receptor antagonist and tumor necrosis factor-alpha are elevated in children with Langerhans cell histiocytosisJ Pediatr Hematol Oncol200325648048312794527
- IshiiRMorimotoAIkushimaSHigh serum values of soluble CD154, IL-2 receptor, RANKL and osteoprotegerin in Langerhans cell histiocytosisPediatr Blood Cancer200647219419916358318
- WillmanCLBusqueLGriffithBBLangerhans’-cell histiocytosis (histiocytosis X) – a clonal proliferative diseaseN Engl J Med199433131541608008029
- AricoMNicholsKWhitlockJAFamilial clustering of Langerhans cell histiocytosisBr J Haematol1999107488388810606898
- SuricoGMuggeoPRigilloNGadnerHConcurrent Langerhans cell histiocytosis and myelodysplasia in childrenMed Pediatr Oncol200035442142511025473
- BettsDRLeibundgutKEFeldgesAPlussHJNiggliFKCytogenetic abnormalities in Langerhans cell histiocytosisBr J Cancer19987745525559484810
- da CostaCEEgelerRMHoogeboomMDifferences in telomerase expression by the CD1a+ cells in Langerhans cell histiocytosis reflect the diverse clinical presentation of the diseaseJ Pathol2007212218819717447723
- EgelerRMNegliaJPAricoMThe relation of Langerhans cell histiocytosis to acute leukemia, lymphomas, and other solid tumors. The LCH-Malignancy Study Group of the Histiocyte SocietyHematol Oncol Clin North Am19981223693789561906
- MagniMDi NicolaMCarlo-StellaCIdentical rearrangement of immunoglobulin heavy chain gene in neoplastic Langerhans cells and B-lymphocytes: evidence for a common precursorLeuk Res200226121131113312443887
- FeldmanALBertholdFArceciRJClonal relationship between precursor T-lymphoblastic leukaemia/lymphoma and Langerhans-cell histiocytosisLancet Oncol20056643543715925822
- LamanJDLeenenPJAnnelsNEHogendoornPCEgelerRMLangerhans-cell histiocytosis “insight into DC biology”Trends Immunol200324419019612697451
- HutterCKauerMSimonitsch-KluppINotch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cellsBlood2012120265199520823074278
- WinterDRJungSAmitIMaking the case for chromatin profiling: a new tool to investigate the immune-regulatory landscapeNat Rev Immunol201515958559426272294
- Badalian-VeryGVergilioJADegarBARecurrent BRAF mutations in Langerhans cell histiocytosisBlood2010116111919192320519626
- BerresMLLimKPPetersTBRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groupsJ Exp Med2014211466968324638167
- EmileJFAblaOFraitagSRevised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineagesBlood2016127222672268126966089
- MinkovMMultisystem Langerhans cell histiocytosis in children: current treatment and future directionsPaediatr Drugs2011132758621351807
- KompDMConcepts in staging and clinical studies for treatment of Langerhans’ cell histiocytosisSemin Oncol19911811823
- LaheyEHistiocytosis X – an analysis of prognostic factorsJ Pediatr19758721841891151558
- LaheyMEPrognostic factors in histiocytosis XAm J Pediatr Hematol Oncol19813157606972178
- MinkovMGroisNHeitgerAPotschgerUWestermeierTGadnerHResponse to initial treatment of multisystem Langerhans cell histiocytosis: an important prognostic indicatorMed Pediatr Oncol200239658158512376981
- DonadieuJPiguetCBernardFA new clinical score for disease activity in Langerhans cell histiocytosisPediatr Blood Cancer200443777077615390280
- LavinPTOsbandMEEvaluating the role of therapy in histiocytosis-X. Clinical studies, staging, and scoringHematol Oncol Clin North Am19871135473499431
- TitgemeyerCGroisNMinkovMFlucher-WolframBGatterer-MenzIGadnerHPattern and course of single-system disease in Langerhans cell histiocytosis data from the DAL-HX 83- and 90-studyMed Pediatr Oncol200137210811411496348
- BroadbentVGadnerHCurrent therapy for Langerhans cell histiocytosisHematol Oncol Clin North Am19981223273389561903
- GadnerHGroisNAricoMA randomized trial of treatment for multisystem Langerhans’ cell histiocytosisJ Pediatr2001138572873411343051
- AllenCELadischSMcClainKLHow I treat Langerhans cell histiocytosisBlood20151261263525827831
- BroadbentVGadnerHKompDMLadischSHistiocytosis syndromes in children: II. Approach to the clinical and laboratory evaluation of children with Langerhans cell histiocytosis. Clinical Writing Group of the Histiocyte SocietyMed Pediatr Oncol19891764924952685528
- HauptRMinkovMAstigarragaILangerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work-up, and treatment for patients till the age of 18 yearsPediatr Blood Cancer201360217518423109216
- BerryDHGresikMMaybeeDMarcusRHistiocytosis X in bone onlyMed Pediatr Oncol19901842922942192248
- BolliniGJouveJLGentetJCJacquemierMBouyalaJMBone lesions in histiocytosis XJ Pediatr Orthop19911144694771860945
- FiorilloASadileFDe ChiaraCBone lesions in Langerhans cell histiocytosisClin Pediatr (Phila)19933221181208432075
- KilpatrickSEWengerDEGilchristGSShivesTCWollanPCUnniKKLangerhans’ cell histiocytosis (histiocytosis X) of bone. A clinicopathologic analysis of 263 pediatric and adult casesCancer19957612247124848625073
- LauLMStuurmanKWeitzmanSSkeletal Langerhans cell histiocytosis in children: permanent consequences and health-related quality of life in long-term survivorsPediatr Blood Cancer200850360761217973322
- WomerRBRaneyRBJrD’AngioGJHealing rates of treated and untreated bone lesions in histiocytosis XPediatrics19857622862883875075
- MorimotoAIshidaYSuzukiNNationwide survey of single-system single site Langerhans cell histiocytosis in JapanPediatr Blood Cancer20105419810219728332
- CohenMZornozaJCangirAMurrayJAWallaceSDirect injection of methylprednisolone sodium succinate in the treatment of solitary eosinophilic granuloma of bone: a report of 9 casesRadiology198013622892937403498
- EgelerRMThompsonRCJrVoutePANesbitMEJrIntralesional infiltration of corticosteroids in localized Langerhans’ cell histiocytosisJ Pediatr Orthop19921268118141452756
- AblaOEgelerRMWeitzmanSLangerhans cell histiocytosis: current concepts and treatmentsCancer Treat Rev201036435435920188480
- ArceciRJBrennerMKPritchardJControversies and new approaches to treatment of Langerhans cell histiocytosisHematol Oncol Clin North Am19981223393579561904
- McClainKLDrug therapy for the treatment of Langerhans cell histiocytosisExpert Opin Pharmacother20056142435244116259575
- MonsereenusornCRodriguez-GalindoCClinical characteristics and treatment of Langerhans Cell histiocytosisHematol Oncol Clin North Am201529585387326461147
- DonadieuJBernardFvan NoeselMCladribine and cytarabine in refractory multisystem Langerhans cell histiocytosis: results of an international phase 2 studyBlood2015126121415142326194764
- GadnerHGroisNPotschgerUImproved outcome in multisystem Langerhans cell histiocytosis is associated with therapy intensificationBlood200811152556256218089850
- GadnerHMinkovMGroisNTherapy prolongation improves outcome in multisystem Langerhans cell histiocytosisBlood2013121255006501423589673
- MinkovMGroisNBroadbentVCeciAJakobsonALadischSCyclosporine A therapy for multisystem langerhans cell histiocytosisMed Pediatr Oncol199933548248510531573
- WeitzmanSBraierJDonadieuJ2′-Chlorodeoxyadenosine (2-CdA) as salvage therapy for Langerhans cell histiocytosis (LCH): results of the LCH-S-98 protocol of the histiocyte societyPediatr Blood Cancer20095371271127619731321
- MinkovMRodriguez-GalindoCTreatment of Langerhans cell histiocytosis: it is time to learn from the pastBr J Haematol2015171114814925816900
- MinkovMSteinerMPotschgerUReactivations in multisystem Langerhans cell histiocytosis: data of the international LCH registryJ Pediatr20081535700705705.e701e70218589441
- MorimotoAKobayashiRMaedaMAsamiKBesshoFImashukuSImpact of reactivation on the sequelae of multi-system Langerhans cell histiocytosis patientsPediatr Blood Cancer2008504931932 author reply 93217729246
- PollonoDReyGLatellaARossoDChantadaGBraierJReactivation and risk of sequelae in Langerhans cell histiocytosisPediatr Blood Cancer200748769669917252574
- BernardFThomasCBertrandYMulti-centre pilot study of 2-chlorodeoxyadenosine and cytosine arabinoside combined chemotherapy in refractory Langerhans cell histiocytosis with haematological dysfunctionEur J Cancer200541172682268916291085
- SteinerMMatthes-MartinSAttarbaschiAImproved outcome of treatment-resistant high-risk Langerhans cell histiocytosis after allogeneic stem cell transplantation with reduced-intensity conditioningBone Marrow Transplant200536321522515937510
- AkkariVDonadieuJPiguetCHematopoietic stem cell transplantation in patients with severe Langerhans cell histiocytosis and hematological dysfunction: experience of the French Langerhans Cell Study GroupBone Marrow Transplant200331121097110312796789
- AblaOWeitzmanSTreatment of Langerhans cell histiocytosis: role of BRAF/MAPK inhibitionHematol Am Soc Hematol Educ Program201520151565570
- AllenCEParsonsDWBiological and clinical significance of somatic mutations in Langerhans cell histiocytosis and related histiocytic neoplastic disordersHematol Am Soc Hematol Educ Program20152015559564
- BrownNAFurtadoLVBetzBLHigh prevalence of somatic MAP2K1 mutations in BRAF V600E-negative Langerhans cell histiocytosisBlood2014124101655165824982505
- ChakrabortyRHamptonOAShenXMutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesisBlood2014124193007301525202140
- DiamondELDurhamBHHarocheJDiverse and targetable kinase alterations drive histiocytic neoplasmsCancer Discov20166215416526566875
- NelsonDSvan HalterenAQuispelWTMAP2K1 and MAP3K1 mutations in Langerhans cell histiocytosisGenes Chromosomes Cancer201554636136825899310
- HymanDMDiamondELVibatCRProspective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disordersCancer Discov201551647125324352
- BubolzAMWeissingerSEStenzingerAPotential clinical implications of BRAF mutations in histiocytic proliferationsOncotarget20145124060407024938183
- CharlesJBeaniJCFiandrinoGBusserBMajor response to vemurafenib in patient with severe cutaneous Langerhans cell histiocytosis harboring BRAF V600E mutationJ Am Acad Dermatol2014713e97e9925128147
- HarocheJCohen-AubartFEmileJFDramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutationBlood201312191495150023258922
- HarocheJCohen-AubartFEmileJFReproducible and sustained efficacy of targeted therapy with vemurafenib in patients with BRAF(V600E)-mutated Erdheim-Chester diseaseJ Clin Oncol201533541141825422482
- HeritierSJehanneMLevergerGVemurafenib use in an infant for high-risk Langerhans cell histiocytosisJAMA Oncol20151683683826180941
- HymanDMPuzanovISubbiahVVemurafenib in multiple nonmelanoma cancers with BRAF V600 mutationsN Engl J Med2015373872673626287849
- HarocheJCohen-AubartFEmileJFDonadieuJAmouraZVemurafenib as first line therapy in BRAF-mutated Langerhans cell histiocytosisJ Am Acad Dermatol2015731e29e3026089069
- BrownRECyclo-oxygenase-2 in the osteolytic lesions of Langerhans cell histiocytosisMed Pediatr Oncol200034431110742083
- BrownREBrief communication: morphoproteomic analysis of osteolytic Langerhans cell histiocytosis with therapeutic implicationsAnn Clin Lab Sci200535213113615943175
- ArzooKSadeghiSPullarkatVPamidronate for bone pain from osteolytic lesions in Langerhans’-cell histiocytosisN Engl J Med2001345322511463032
- BrownREMore on pamidronate in Langerhans’-cell histiocytosisN Engl J Med2001345201503
- ElomaaIBlomqvistCPorkkaLHolmstromTExperiences of clodronate treatment of multifocal eosinophilic granuloma of boneJ Intern Med1989225159612918272
- KamizonoJOkadaYShirahataATanakaYBisphosphonate induces remission of refractory osteolysis in langerhans cell histiocytosisJ Bone Miner Res200217111926192812412797
- MunnSEOlliverLBroadbentVPritchardJUse of indomethacin in Langerhans cell histiocytosisMed Pediatr Oncol199932424724910102016
- HenterJIKarlenJCalmingUBernstrandCAnderssonUFadeelBSuccessful treatment of Langerhans’-cell histiocytosis with etanerceptN Engl J Med20013452115771578
- BrodowiczTHemetsbergerMWindhagerRDenosumab for the treatment of giant cell tumor of the boneFuture Oncol201511131881189426161925
- DahiyaNKhadkaASharmaAKGuptaAKSinghNBrashierDBDenosumab: a bone antiresorptive drugMed J Armed Forces India2015711717525609868
- GoldenbergMMPharmaceutical approval updateP T201338844344524222975
- VaishyaRAgarwalAKVijayV“Salvage Treatment” of aggressive giant cell tumor of bones with denosumabCureus201577e29126251767
- HartCVogelhuberMWolffDAnakoinosis: communicative reprogramming of tumor systems – for rescuing from chemorefractory neoplasiaCancer Microenviron201582759226259724
- SenechalBElainGJeziorskiEExpansion of regulatory T cells in patients with Langerhans cell histiocytosisPLoS Med200748e25317696642
- GatalicaZBilalovicNPalazzoJPDisseminated histiocytoses biomarkers beyond BRAFV600E: frequent expression of PD-L1Oncotarget2015623198191982526110571