Cyclophilin A Plays Potential Roles in a Rat Model of Asthma and Suppression of Immune Response

References

• Global Initiative for Asthma(2020). Global strategy for asthma management and prevention; 2020. Available from: www.ginasthma.org. Accessed April 8, 2021.
   Google Scholar
• Soriano JB, Abajobir AA, Abate KH, et al. Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Respir Med. 2017;5(9):691–706. doi:10.1016/S2213-2600(17)30293-X
   PubMed Web of Science ®Google Scholar
• Fergeson JE, Patel SS, Lockey RF. Acute asthma, prognosis, and treatment. J Allergy Clin Immunol. 2017;139(2):438–447. doi:10.1016/j.jaci.2016.06.054
   PubMed Web of Science ®Google Scholar
• McKeever T, Harrison TW, Hubbard R, Shaw D. Inhaled corticosteroids and the risk of pneumonia in people with asthma: a case-control study. Chest. 2013;144(6):1788–1794. doi:10.1378/chest.13-0871
   PubMed Web of Science ®Google Scholar
• Yim RP, Koumbourlis AC. Tolerance & resistance to beta(2)-agonist bronchodilators. Paediatr Respir Rev. 2013;14(3):195–198. doi:10.1016/j.prrv.2012.11.002
   Web of Science ®Google Scholar
• Guan WJ, Zheng JP, Gao Y, et al. Responsiveness to leukotriene D4 and methacholine for predicting efficacy of montelukast in asthma. J Thorac Dis. 2013;5(3):298–301. doi:10.3978/j.issn.2072-1439.2013.02.01
   Web of Science ®Google Scholar
• Yalcin AD, Bisgin A, Cetinkaya R, Yildirim M, Gorczynski RM. Clinical course and side effects of anti-IgE monoclonal antibody in patients with severe persistent asthma. Clin Lab. 2013;59(1–2):71–77. doi:10.7754/Clin.Lab.2012.120406
   PubMed Web of Science ®Google Scholar
• Gibson PG, Yang IA, Upham JW, et al. Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. Lancet. 2017;390(10095):659–668. doi:10.1016/S0140-6736(17)31281-3
   PubMed Web of Science ®Google Scholar
• Caminati M, Pham DL, Bagnasco D, Canonica GW. Type 2 immunity in asthma. World Allergy Organ. 2018;11(1):13. doi:10.1186/s40413-018-0192-5
   PubMed Web of Science ®Google Scholar
• Olin JT, Wechsler ME. Asthma: pathogenesis and novel drugs for treatment. BMJ. 2014;349(nov24 8):g5517. doi:10.1136/bmj.g5517
   Web of Science ®Google Scholar
• Tokunaga A, Sugiyama D, Maeda Y, et al. Selective inhibition of low-affinity memory CD8(+) T cells by corticosteroids. J Exp Med. 2019;216(12):2701–2713. doi:10.1084/jem.20190738
   PubMed Web of Science ®Google Scholar
• Williams DM. Clinical pharmacology of corticosteroids. Respir Care. 2018;63(6):655–670. doi:10.4187/respcare.06314
   PubMed Web of Science ®Google Scholar
• Kay AB. Immunosuppressive agents in chronic severe asthma. Allergy Proc. 1994;15(3):147–150. doi:10.2500/108854194778702838
   Google Scholar
• Sihra BS, Kon OM, Durham SR, et al. Effect of cyclosporin A on the allergen-induced late asthmatic reaction. Thorax. 1997;52(5):447–452. doi:10.1136/thx.52.5.447
   Web of Science ®Google Scholar
• Alexander AG, Barnes NC, Kay AB. Trial of cyclosporin in corticosteroid-dependent chronic severe asthma. Lancet. 1992;339(8789):324–328. doi:10.1016/0140-6736(92)91646-P
   PubMed Web of Science ®Google Scholar
• Evans DJ, Cullinan P, Geddes DM. Cyclosporin as an oral corticosteroid sparing agent in stable asthma. Cochrane Database Syst Rev. 2000;5:CD002993. doi:10.1002/14651858.CD002993
   Google Scholar
• Survase SA, Kagliwal LD, Annapure US, Singhal RS. Cyclosporin A–a review on fermentative production, downstream processing and pharmacological applications. Biotechnol Adv. 2011;29(4):418–435. doi:10.1016/j.biotechadv.2011.03.004
   PubMed Web of Science ®Google Scholar
• Colgan J, Asmal M, Yu B, Luban J. Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine. J Immunol. 2005;174(10):6030–6038. doi:10.4049/jimmunol.174.10.6030
   PubMed Web of Science ®Google Scholar
• Handschumacher RE, Harding MW, Rice J, Drugge RJ, Speicher DW. Cyclophilin: a specific cytosolic binding protein for cyclosporin A. Science. 1984;226(4674):544–547. doi:10.1126/science.6238408
   PubMed Web of Science ®Google Scholar
• Seko Y, Fujimura T, Taka H, et al. Hypoxia followed by reoxygenation induces secretion of cyclophilin A from cultured rat cardiac myocytes. Biochem Biophys Res Commun. 2004;317(1):162–168. doi:10.1016/j.bbrc.2004.03.021
   PubMed Web of Science ®Google Scholar
• Sherry B, Yarlett N, Strupp A, Cerami A. Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages. Proc Natl Acad Sci U S A. 1992;89(8):3511–3515. doi:10.1073/pnas.89.8.3511
   PubMed Web of Science ®Google Scholar
• Jin ZG, Melaragno MG, Liao DF, et al. Cyclophilin A is a secreted growth factor induced by oxidative stress. Circ Res. 2000;87(9):789–796. doi:10.1161/01.RES.87.9.789
   PubMed Web of Science ®Google Scholar
• Brazin KN, Mallis RJ, Fulton DB, Andreotti AH. Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A. Proc Natl Acad Sci U S A. 2002;99(4):1899–1904. doi:10.1073/pnas.042529199
   Web of Science ®Google Scholar
• Schwartzberg PL, Finkelstein LD, Readinger JA. TEC-family kinases: regulators of T-helper-cell differentiation. Nat Rev Immunol. 2005;5(4):284–295. doi:10.1038/nri1591
   PubMed Web of Science ®Google Scholar
• Colgan J, Asmal M, Neagu M, et al. Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk. Immunity. 2004;21(2):189–201. doi:10.1016/j.immuni.2004.07.005
   PubMed Web of Science ®Google Scholar
• Li J, Chen J, Zhang L, et al. One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation. Bioorg Med Chem. 2006;14(16):5527–5534. doi:10.1016/j.bmc.2006.04.026
   Web of Science ®Google Scholar
• Kofron JL, Kuzmic P, Kishore V, Colon-Bonilla E, Rich DH. Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay. Biochemistry. 1991;30(25):6127–6134. doi:10.1021/bi00239a007
   Web of Science ®Google Scholar
• Yin LM, Li HY, Zhang QH, et al. Effects of S100A9 in a rat model of asthma and in isolated tracheal spirals. Biochem Biophys Res Commun. 2010;398(3):547–552. doi:10.1016/j.bbrc.2010.06.116
   PubMed Web of Science ®Google Scholar
• Xu Y-D, Wang Y, Yin L-M, et al. S100A8 protein attenuates airway hyperresponsiveness by suppressing the contraction of airway smooth muscle. Biochem Biophys Res Commun. 2017;484(1):184–188. doi:10.1016/j.bbrc.2017.01.033
   Web of Science ®Google Scholar
• Kim S-H, Lessner SM, Sakurai Y, Galis ZS. Cyclophilin A as a novel biphasic mediator of endothelial activation and dysfunction. Am J Pathol. 2004;164(5):1567–1574. doi:10.1016/S0002-9440(10)63715-7
   PubMed Web of Science ®Google Scholar
• Sun L, Yu G, Yang S, Zhang L. Effects of hydrocortisone on the differentiation of human T helper 2 cells. Scand J Immunol. 2011;73(3):208–214. doi:10.1111/j.1365-3083.2010.02500.x
   Web of Science ®Google Scholar
• Packard KA, Khan MM. Effects of histamine on Th1/Th2 cytokine balance. Int Immunopharmacol. 2003;3(7):909–920. doi:10.1016/S1567-5769(02)00235-7
   PubMed Web of Science ®Google Scholar
• Watanabe N, Kobayashi A. Nippostrongylus brasiliensis: radioresistant IgE antibody-forming cells in infected rats. Exp Parasitol. 1989;68(2):216–222. doi:10.1016/0014-4894(89)90100-8
   Web of Science ®Google Scholar
• Barnig C, Frossard N, Levy BD. Towards targeting resolution pathways of airway inflammation in asthma. Pharmacol Ther. 2018;186:98–113. doi:10.1016/j.pharmthera.2018.01.004
   PubMed Web of Science ®Google Scholar
• PubChem Compound Summary for CID 5754, Hydrocortisone. National library of medicine (US), national center for biotechnology information; 2021. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Hydrocortisone. Accessed April 8, 2021.
   Google Scholar
• Katial RK, Sachanandani D, Pinney C, Lieberman MM. Cytokine production in cell culture by peripheral blood mononuclear cells from immunocompetent hosts. Clin Diagn Lab Immunol. 1998;5(1):78–81. doi:10.1128/CDLI.5.1.78-81.1998
   PubMedGoogle Scholar
• Stemmy EJ, Balsley MA, Jurjus RA, et al. Blocking cyclophilins in the chronic phase of asthma reduces the persistence of leukocytes and disease reactivation. Am J Respir Cell Mol Biol. 2011;45(5):991–998. doi:10.1165/rcmb.2011-0007OC
   Web of Science ®Google Scholar
• Stemmy EJ, Benton AS, Lerner J, et al. Extracellular cyclophilin levels associate with parameters of asthma in phenotypic clusters. J Asthma. 2011;48(10):986–993. doi:10.3109/02770903.2011.623334
   PubMed Web of Science ®Google Scholar
• Benton AS, Wang Z, Lerner J, et al. Overcoming heterogeneity in pediatric asthma: tobacco smoke and asthma characteristics within phenotypic clusters in an African American cohort. J Asthma. 2010;47(7):728–734. doi:10.3109/02770903.2010.491142
   PubMed Web of Science ®Google Scholar
• Hershenson MB, Brown M, Camoretti-Mercado B, Solway J. Airway smooth muscle in asthma. Annu Rev Pathol. 2008;3(1):523–555. doi:10.1146/annurev.pathmechdis.1.110304.100213
   Web of Science ®Google Scholar
• Vathenen AS, Knox AJ, Higgins BG, Britton JR, Tattersfield AE. Rebound increase in bronchial responsiveness after treatment with inhaled terbutaline. Lancet. 1988;1(8585):554–558. doi:10.1016/S0140-6736(88)91352-9
   Web of Science ®Google Scholar
• Barnes PJ. Neural control of human airways in health and disease. Am Rev Respir Dis. 1986;134(6):1289–1314. doi:10.1164/arrd.1986.134.5.1289
   Google Scholar
• Lefcoe NM. The effect of hydrocortisone hemisuccinate on tracheal smooth muscle of the guinea pig and cat. J Allergy. 1956;27(4):352–358. doi:10.1016/0021-8707(56)90074-0
   Google Scholar
• Andersson RG, Kovesi G. The effect of hydrocortisone on tension and cyclic AMP metabolism in tracheal smooth muscle. Experientia. 1974;30(7):784–786. doi:10.1007/BF01924186
   Google Scholar
• Kim K, Oh IK, Yoon KS, et al. Antioxidant activity is required for the protective effects of cyclophilin A against oxidative stress. Mol Med Rep. 2015;12(1):712–718. doi:10.3892/mmr.2015.3392
   Web of Science ®Google Scholar
• Cheng F, Yuan W, Cao M, et al. Cyclophilin A protects cardiomyocytes against hypoxia/reoxygenation-induced apoptosis via the AKT/Nox2 pathway. Oxid Med Cell Longev. 2019;2019:2717986. doi:10.1155/2019/2717986
   Web of Science ®Google Scholar
• Fujisawa T. Role of oxygen radicals on bronchial asthma. Curr Drug Targets Inflamm Allergy. 2005;4(4):505–509. doi:10.2174/1568010054526304
   Google Scholar