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ORIGINAL RESEARCH

IL-13 Regulates Orai1 Expression in Human Bronchial Smooth Muscle Cells and Airway Remodeling in Asthma Mice Model via LncRNA H19

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Pages 1245-1261 | Received 28 Jan 2022, Accepted 20 Aug 2022, Published online: 07 Sep 2022

References

  • Papi A, Brightling C, Pedersen SE, Reddel HK. Asthma. Lancet. 2018;391(10122):783–800.
  • Akdis CA, Arkwright PD, Bruggen MC, et al. Type 2 immunity in the skin and lungs. Allergy. 2020;75(7):1582–1605.
  • Saglani S, Lui S, Ullmann N, et al. IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma. J Allergy Clin Immunol. 2013;132(3):676–685 e613.
  • Manson ML, Safholm J, James A, et al. IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways. J Allergy Clin Immunol. 2020;145(3):808–817 e802.
  • Wang X, Xu C, Ji J, et al. IL-4/IL-13 upregulates Sonic hedgehog expression to induce allergic airway epithelial remodeling. Am J Physiol Lung Cell Mol Physiol. 2020;318(5):L888–L899.
  • Doucet C, Brouty-Boye D, Pottin-Clemenceau C, Canonica GW, Jasmin C, Azzarone B. Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma. J Clin Invest. 1998;101(10):2129–2139.
  • McKnight CG, Potter C, Finkelman FD. IL-4Ralpha expression by airway epithelium and smooth muscle accounts for nearly all airway hyperresponsiveness in murine allergic airway disease. Mucosal Immunol. 2020;13(2):283–292.
  • Wang YM, Xu WJ, Xiang LL, et al. Store-operated calcium entry-associated regulatory factor regulates airway inflammation and airway remodeling in asthma mice models. Am J Physiol Lung Cell Mol Physiol. 2021;321(3):L533–L544.
  • Gao YD, Zou JJ, Zheng JW, et al. Promoting effects of IL-13 on Ca2+ release and store-operated Ca2+ entry in airway smooth muscle cells. Pulm Pharmacol Ther. 2010;23(3):182–189.
  • Prakriya M, Lewis RS. Store-Operated Calcium Channels. Physiol Rev. 2015;95(4):1383–1436.
  • Zou JJ, Gao YD, Geng S, Yang J. Role of STIM1/Orai1-mediated store-operated Ca(2)(+) entry in airway smooth muscle cell proliferation. J Appl Physiol. 2011;110(5):1256–1263.
  • Spinelli AM, Gonzalez-Cobos JC, Zhang X, et al. Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration. Pflugers Arch. 2012;464(5):481–492.
  • Sathish V, Abcejo AJ, Thompson MA, Sieck GC, Prakash YS, Pabelick CM. Caveolin-1 regulation of store-operated Ca(2+) influx in human airway smooth muscle. Eur Respir J. 2012;40(2):470–478.
  • Atianand MK, Caffrey DR, Fitzgerald KA. Immunobiology of Long Noncoding RNAs. Annu Rev Immunol. 2017;35:177–198.
  • Ali T, Grote P. Beyond the RNA-dependent function of LncRNA genes. Elife. 2020;9:548.
  • Zhu X, Wei Y, Dong J. Long Noncoding RNAs in the Regulation of Asthma: current Research and Clinical Implications. Front Pharmacol. 2020;11:532849.
  • Zheng M, Hong W, Gao M, et al. Long Noncoding RNA COPDA1 Promotes Airway Smooth Muscle Cell Proliferation in Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2019;61(5):584–596.
  • Mao Z, Shi Y, Cao Q, et al. Transcriptional regulation on the gene expression signature in combined allergic rhinitis and asthma syndrome. Epigenomics. 2018;10(2):119–131.
  • Su H, Xu X, Yan C, et al. LncRNA H19 promotes the proliferation of pulmonary artery smooth muscle cells through AT1R via sponging let-7b in monocrotaline-induced pulmonary arterial hypertension. Respir Res. 2018;19(1):254.
  • Lopez-Urrutia E, Bustamante Montes LP. Ladron de Guevara Cervantes D, Perez-Plasencia C, Campos-Parra AD. Crosstalk Between Long Non-coding RNAs, Micro-RNAs and mRNAs: deciphering Molecular Mechanisms of Master Regulators in Cancer. Front Oncol. 2019;9:669.
  • Ma J, Zhang L, Hao J, Li N, Tang J, Hao L. Up-regulation of microRNA-93 inhibits TGF-beta1-induced EMT and renal fibrogenesis by down-regulation of Orai1. J Pharmacol Sci. 2018;136(4):218–227.
  • Lu Q, Guo Z, Xie W, et al. The lncRNA H19 Mediates Pulmonary Fibrosis by Regulating the miR-196a/COL1A1 Axis. Inflammation. 2018;41(3):896–903.
  • Xiao Y, Liu R, Li X, et al. Long Noncoding RNA H19 Contributes to Cholangiocyte Proliferation and Cholestatic Liver Fibrosis in Biliary Atresia. Hepatology. 2019;70(5):1658–1673.
  • Woo LN, Guo WY, Wang X, et al. A 4-Week Model of House Dust Mite (HDM) Induced Allergic Airways Inflammation with Airway Remodeling. Sci Rep. 2018;8(1):6925.
  • Wills-Karp M, Luyimbazi J, Xu X, et al. Interleukin-13: central mediator of allergic asthma. Science. 1998;282(5397):2258–2261.
  • Ingram JL, Kraft M. IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies. J Allergy Clin Immunol. 2012;130(4):829–842.
  • Sugita K, Steer CA, Martinez-Gonzalez I, et al. Type 2 innate lymphoid cells disrupt bronchial epithelial barrier integrity by targeting tight junctions through IL-13 in asthmatic patients. J Allergy Clin Immunol. 2018;141(1):300–310 e311.
  • Yang SJ, Allahverdian S, Saunders ADR, Liu E, Dorscheid DR. IL-13 signaling through IL-13 receptor alpha2 mediates airway epithelial wound repair. FASEB J. 2019;33(3):3746–3757.
  • Sherrill JD, Kiran KC, Blanchard C, et al. Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing. Genes Immun. 2014;15(6):361–369.
  • Roy S, Schmeier S, Kaczkowski B, et al. Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages. Sci Rep. 2018;8(1):6758.
  • Yue L, Yin X, Hao F, et al. Long Noncoding RNA Linc00632 Inhibits Interleukin-13-Induced Inflammatory Cytokine and Mucus Production in Nasal Epithelial Cells. J Innate Immun. 2020;12(1):116–128.
  • Wang L, Lv Q, Song X, Jiang K, Zhang J. ADRB2 suppresses IL-13-induced allergic rhinitis inflammatory cytokine regulated by miR-15a-5p. Hum Cell. 2019;32(3):306–315.
  • Su Y, Wang J, Zou J, Han W, Li S. miR-330 regulates interleukin-13-induced MUC5AC secretion by targeting Munc18b in human bronchial epithelial cells. Int J Clin Exp Pathol. 2018;11(7):3463–3470.
  • Solberg OD, Ostrin EJ, Love MI, et al. Airway epithelial miRNA expression is altered in asthma. Am J Respir Crit Care Med. 2012;186(10):965–974.
  • Chiba Y, Tanabe M, Goto K, Sakai H, Misawa M. Down-regulation of miR-133a contributes to up-regulation of Rhoa in bronchial smooth muscle cells. Am J Respir Crit Care Med. 2009;180(8):713–719.
  • Chiba Y, Ando Y, Kato Y, Hanazaki M, Sakai H. Down-regulation of miR-140-3p is a cause of the interlukin-13-induced up-regulation of RhoA protein in bronchial smooth muscle cells. Small GTPases. 2021;1:1–6.
  • Yu H, Qi N, Zhou Q. LncRNA H19 Inhibits Proliferation and Migration of Airway Smooth Muscle Cells Induced by PDGF-BB Through miR-21/PTEN/Akt Axis. J Asthma Allergy. 2021;14:71–80.
  • Bousquet J, Agache I, Blain H, et al. Management of anaphylaxis due to COVID-19 vaccines in the elderly. Allergy. 2021;1:55.
  • Dey BK, Pfeifer K, The DA. H19 long noncoding RNA gives rise to microRNAs miR-675-3p and miR-675-5p to promote skeletal muscle differentiation and regeneration. Genes Dev. 2014;28(5):491–501.
  • Abdelmohsen K, Srikantan S, Tominaga K, et al. Growth inhibition by miR-519 via multiple p21-inducing pathways. Mol Cell Biol. 2012;32(13):2530–2548.
  • Deng W, Wang J, Zhang J, Cai J, Bai Z, Zhang Z. Orai1, a Direct Target of microRNA-519, Promotes Progression of Colorectal Cancer via Akt/GSK3beta Signaling Pathway. Dig Dis Sci. 2016;61(6):1553–1560.
  • Zhang S, Al-Maghout T, Cao H, et al. Gut Bacterial Metabolite Urolithin A (UA) Mitigates Ca(2+) Entry in T Cells by Regulating miR-10a-5p. Front Immunol. 2019;10:1737.
  • Zhang S, Al-Maghout T, Zhou Y, et al. Role of Dicer Enzyme in the Regulation of Store Operated Calcium Entry (SOCE) in CD4+ T Cells. Cell Physiol Biochem. 2016;39(4):1360–1368.
  • Miao C, Bai L, Yang Y, Huang J. Dysregulation of lncRNAs in Rheumatoid Arthritis: biomarkers, Pathogenesis and Potential Therapeutic Targets. Front Pharmacol. 2021;12:652751.
  • Zhang X, Ji S, Cai G, et al. H19 Increases IL-17A/IL-23 Releases via Regulating VDR by Interacting with miR675-5p/miR22-5p in Ankylosing Spondylitis. Mol Ther Nucleic Acids. 2020;19:393–404.
  • Wang B, Suen CW, Ma H, et al. The Roles of H19 in Regulating Inflammation and Aging. Front Immunol. 2020;11:579687.
  • Gamaev L, Mizrahi L, Friehmann T, et al. The pro-oncogenic effect of the lncRNA H19 in the development of chronic inflammation-mediated hepatocellular carcinoma. Oncogene. 2021;40(1):127–139.
  • Lan X, Sun W, Dong W, et al. Downregulation of long noncoding RNA H19 contributes to the proliferation and migration of papillary thyroid carcinoma. Gene. 2018;646:98–105.
  • Chen C, Liu WR, Zhang B, et al. LncRNA H19 downregulation confers erlotinib resistance through upregulation of PKM2 and phosphorylation of AKT in EGFR-mutant lung cancers. Cancer Lett. 2020;486:58–70.
  • Yuan Y, Li X, Chu Y, Ye G, Yang L, Dong Z. Long Non-coding RNA H19 Augments Hypoxia/Reoxygenation-Induced Renal Tubular Epithelial Cell Apoptosis and Injury by the miR-130a/BCL2L11 Pathway. Front Physiol. 2021;12:632398.
  • Austin PJ, Tsitsiou E, Boardman C, et al. Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle. J Allergy Clin Immunol. 2017;139(3):780–789.