Poor Asthma Control in Schoolchildren May Lead to Lower Lung Function Trajectory from Childhood to Early Adulthood: A Japanese Cohort Study

References

• GBD 2015 Chronic Respiratory Disease Collaborators. Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Respir Med. 2017;5(9):691–706. doi:10.1016/S2213-2600(17)30293-X
   PubMed Web of Science ®Google Scholar
• Global Asthma Network. The global asthma report; 2018. Available from: http://www.globalasthmanetwork.org/. Accessed April 1, 2021.
   Google Scholar
• Ebmeier S, Thayabaran D, Braithwaite I, Bénamara C, Weatherall M, Beasley R. Trends in international asthma mortality: analysis of data from the WHO mortality database from 46 countries (1993–2012). Lancet. 2017;390(10098):935–945. doi:10.1016/S0140-6736(17)31448-4
   PubMed Web of Science ®Google Scholar
• Ministry of health, labour and welfare, Japan. Available from: http://www.mhlw.go.jp/. Accessed April 1, 2021. Japanese.
   Google Scholar
• Ichinose M, Sugiura H, Nagase H, et al. Japanese guidelines for adult asthma 2017. Allergol Int. 2017;66(2):163–189. doi:10.1016/j.alit.2016.12.005
   PubMed Web of Science ®Google Scholar
• Bourdin A, Fabry-Vendrand C, Ostinelli J, et al. The burden of severe asthma in France: a case-control study using a medical claims database. J Allergy Clin Immunol Pract. 2019;7(5):1477–1487. doi:10.1016/j.jaip.2018.12.029
   PubMed Web of Science ®Google Scholar
• Omachi TA, Iribarren C, Sarkar U, et al. Risk factors for death in adults with severe asthma. Ann Allergy Asthma Immunol. 2008;101(2):130–136. doi:10.1016/S1081-1206(10)60200-1
   PubMed Web of Science ®Google Scholar
• Sears MR. Consequences of long-term inflammation. The natural history of asthma. Clin Chest Med. 2000;21(2):315–329. doi:10.1016/s0272-5231(05)70269-0
   PubMed Web of Science ®Google Scholar
• Ulrik CS. Outcome of asthma: longitudinal changes in lung function. Eur Respir J. 1999;13(4):904–918. doi:10.1034/j.1399-3003.1999.13d35.x
   PubMed Web of Science ®Google Scholar
• Okayama Y, Kawayama T, Kinoshita T, et al. Impact of airflow obstruction on long-term mortality in patients with asthma in Japan. Allergol Int. 2019;68(4):462–469. doi:10.1016/j.alit.2019.04.009
   PubMed Web of Science ®Google Scholar
• Lange P, Çolak Y, Ingebrigtsen TS, Vestbo J, Marott JL. Long-term prognosis of asthma, chronic obstructive pulmonary disease, and asthma-chronic obstructive pulmonary disease overlap in the Copenhagen City Heart study: a prospective population-based analysis. Lancet Respir Med. 2016;4(6):454–462. doi:10.1016/S2213-2600(16)00098-9
   PubMed Web of Science ®Google Scholar
• Siroux V, Boudier A, Dolgopoloff M, et al. Forced midexpiratory flow between 25% and 75% of forced vital capacity is associated with long-term persistence of asthma and poor asthma outcomes. J Allergy Clin Immunol. 2016;137(6):1709–1716.e6. doi:10.1016/j.jaci.2015.10.029
   PubMed Web of Science ®Google Scholar
• Huang S, Vasquez MM, Halonen M, Martinez FD, Guerra S. Asthma, airflow limitation and mortality risk in the general population. Eur Respir J. 2015;45(2):338–346. doi:10.1183/09031936.00108514
   PubMed Web of Science ®Google Scholar
• Pijnenburg MW, Fleming L. Advances in understanding and reducing the burden of severe asthma in children. Lancet Respir Med. 2020;8(10):1032–1044. doi:10.1016/S2213-2600(20)30399-4
   PubMed Web of Science ®Google Scholar
• Castagnoli R, Marseglia A, Brambilla I, et al. Severe uncontrolled asthma in children: practical approach on diagnosis and management. Minerva Pediatr. 2020;72(3):196–205. doi:10.23736/S0026-4946.20.05818-1
   PubMed Web of Science ®Google Scholar
• Licari A, Brambilla I, Filippo MD, Poddighe D, Castagnoli R, Marseglia GL. The role of upper airway pathology as a co-morbidity in severe asthma. Expert Rev Respir Med. 2017;11(11):855–865. doi:10.1080/17476348.2017.1381564
   PubMed Web of Science ®Google Scholar
• Fuchs O, Bahmer T, Rabe KF, et al. Asthma transition from childhood into adulthood. Lancet Respir Med. 2017;5:224–234. doi:10.1016/S2213-2600(16)30187-4
   PubMed Web of Science ®Google Scholar
• Trivedi M, Denton E. Asthma in children and adults–what are the differences and what can they tell us about asthma? Front Pediatr. 2019;7:256. doi:10.3389/fped.2019.00256
   PubMed Web of Science ®Google Scholar
• Rennard SI, Drummond MB. Early chronic obstructive pulmonary disease: definition, assessment, and prevention. Lancet. 2015;385(9979):1778–1788. doi:10.1016/S0140-6736(15)60647-X
   PubMed Web of Science ®Google Scholar
• Koefoed HJL, Zwitserloot AM, Vonk JM, Koppelman GH. Asthma, bronchial hyperresponsiveness, allergy and lung function development until early adulthood: a systematic literature review. Pediatr Allergy Immunol. 2021;32(6):1238–1254. doi:10.1111/pai.13516
   PubMed Web of Science ®Google Scholar
• Koefoed HJL, Gehring U, Vonk JM, Koppelman GH. Blood eosinophils associate with reduced lung function growth in adolescent asthmatics. Clin Exp Allergy. 2021;51(4):556–563. doi:10.1111/cea.13818
   PubMed Web of Science ®Google Scholar
• Bui DS, Lodge CJ, Burgess JA, et al. Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life. Lancet Respir Med. 2018;6(7):535–544. doi:10.1016/S2213-2600(18)30100-0
   PubMed Web of Science ®Google Scholar
• Belgrave DCM, Granell R, Turner SW, et al. Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies. Lancet Respir Med. 2018;6(7):526–534. doi:10.1016/S2213-2600(18)30099-7
   PubMed Web of Science ®Google Scholar
• McGeachie MJ, Yates KP, Zhou X, et al. Patterns of growth and decline in lung function in persistent childhood asthma. N Engl J Med. 2016;374(19):1842–1852. doi:10.1056/NEJMoa1513737
   PubMed Web of Science ®Google Scholar
• Lo DK, Beardsmore CB, Roland D, et al. Lung function and asthma control in school-age children managed in UK primary care: a cohort study. Thorax. 2020;75(2):101–107. doi:10.1136/thoraxjnl-2019-213068
   PubMed Web of Science ®Google Scholar
• Pijnenburg MW, Baraldi E, Brand PLP, et al. Monitoring asthma in children. Eur Respir J. 2015;45(4):906–925. doi:10.1183/09031936.00088814
   PubMed Web of Science ®Google Scholar
• Spahn JD, Covar R. Clinical assessment of asthma progression in children and adults. J Allergy Clin Immunol. 2008;121(3):548–557. doi:10.1016/j.jaci.2008.01.012
   PubMed Web of Science ®Google Scholar
• Takase M, Sakata H, Shikada M, et al. Standardization of predicted values of spirogram for Japanese Children (Final Report). Jpn J Pediatr Pulmonol. 2008;9:164–176. Japanese.
   Google Scholar
• Soriano JB, Miravitlles M, García-Río F, et al. Spirometrically-defined restrictive ventilatory defect: population variability and individual determinants. Prim Care Respir J. 2012;21(2):187–193. doi:10.4104/pcrj.2012.00027
   PubMedGoogle Scholar
• Sekerel BE, Civelek E, Karabulut E, et al. Are risk factors of childhood asthma predicting disease persistence in early adulthood different in the developing world? Allergy. 2006;61(7):869–877. doi:10.1111/j.1398-9995.2006.01082.x
   PubMed Web of Science ®Google Scholar
• The Japanese Society for Pediatric Endocrinology. Clinical growth charts. Available from: http://jspe.umin.jp/index.html. Accessed October 6, 2019. Japanese.
   Google Scholar
• Suwa S, Tachibana K, Maesaka H, et al. Longitudinal standards for height and height velocity for Japanese children from birth to maturity. Clin Pediatr Endocrinol. 1992;1(1):5–13. doi:10.1297/cpe.1.5
   Google Scholar
• Duan P, Wang Y, Lin R, et al. Impact of early life exposures on COPD in adulthood: a systematic review and meta-analysis. Respirology. 2021;26(12):1131–1151. doi:10.1111/resp.14144
   PubMed Web of Science ®Google Scholar
• Okyere DO, Bui DS, Washko GR, et al. Predictors of lung function trajectories in population-based studies: a systematic review. Respirology. 2021;26(10):938–959. doi:10.1111/resp.14142
   PubMed Web of Science ®Google Scholar
• Ali KM. Childhood asthma as a risk factor for adult chronic obstructive pulmonary disease: a systematic review and meta-analysis. Expert Rev Respir Med. 2020;29:1–7. doi:10.1080/17476348.2021.1864328
   Web of Science ®Google Scholar
• Leung TF, Tang MF, Leung ASY, Tam WWS, Sy HY, Wong GWK. Trajectory of spirometric and exhaled nitric oxide measurements in Chinese schoolchildren with asthma. Pediatr Allergy Immunol. 2018;29(2):166–173. doi:10.1111/pai.12836
   PubMed Web of Science ®Google Scholar
• Kelly WJ, Hudson I, Raven J, Phelan PD, Pain MC, Olinsky A. Childhood asthma and adult lung function. Am Rev Respir Dis. 1988;138(1):26–30. doi:10.1164/ajrccm/138.1.26
   PubMed Web of Science ®Google Scholar
• Ortega H, Yancey SW, Keene ON, Gunsoy NB, Albers FC, Howarth PH. Asthma exacerbations associated with lung function decline in patients with severe eosinophilic asthma. J Allergy Clin Immunol Pract. 2018;6(3):980–986.e1. doi:10.1016/j.jaip.2017.12.019
   PubMed Web of Science ®Google Scholar
• Silkoff PE, Laviolette M, Singh D, et al. Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study. Respir Res. 2016;17:43. doi:10.1186/s12931-016-0360-5
   PubMed Web of Science ®Google Scholar
• Matsunaga K, Hirano T, Oka A, et al. Progression of irreversible airflow limitation in asthma: correlation with severe exacerbations. J Allergy Clin Immunol Pract. 2015;3(5):759–64.e1. doi:10.1016/j.jaip.2015.05.005
   PubMed Web of Science ®Google Scholar
• O’Byrne PM, Pedersen S, Lamm CJ, Tan WC, Busse WW; START Investigators Group. Severe exacerbations and decline in lung function in asthma. Am J Respir Crit Care Med. 2009;179(1):19–24. doi:10.1164/rccm.200807-1126OC
   PubMed Web of Science ®Google Scholar
• Çolak Y, Afzal S, Nordestgaard BG, et al. Young and middle-aged adults with airflow limitation according to lower limit of normal but not fixed ratio have high morbidity and poor survival: a population-based prospective cohort study. Eur Respir J. 2018;51(3):1702681. doi:10.1183/13993003.02681-2017
   PubMed Web of Science ®Google Scholar
• Swanney MP, Ruppel G, Enright PL, et al. Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction. Thorax. 2008;63(12):1046–1051. doi:10.1136/thx.2008.098483
   PubMed Web of Science ®Google Scholar
• Smith LJ. The lower limit of normal versus a fixed ratio to assess airflow limitation: will the debate ever end? Eur Respir J. 2018;51(3):1800403. doi:10.1183/13993003.00403-2018
   PubMed Web of Science ®Google Scholar
• Hopp RJ, Wilson MC, Pasha MA. Small airway disease in pediatric asthma: the who, what, when, where, why, and how to remediate. A review and commentary. Clin Rev Allergy Immunol. 2020;62(1):145–159. doi:10.1007/s12016-020-08818-1
   PubMed Web of Science ®Google Scholar
• Beydon N, Davis SD, Lombardi E, et al. An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool children. Am J Respir Crit Care Med. 2007;175(12):1304–1345. doi:10.1164/rccm.200605-642ST
   PubMed Web of Science ®Google Scholar
• Deliu M, Fontanella S, Haider S, et al. Longitudinal trajectories of severe wheeze exacerbations from infancy to school age and their association with early-life risk factors and late asthma outcomes. Clin Exp Allergy. 2020;50(3):315–324. doi:10.1111/cea.13553
   PubMed Web of Science ®Google Scholar
• Zeiger RS, Dawson C, Weiss S. Relationships between duration of asthma and asthma severity among children in the Childhood Asthma Management Program (CAMP). J Allergy Clin Immunol. 1999;103(3 Pt 1):376–387. doi:10.1016/s0091-6749(99)70460-4
   PubMed Web of Science ®Google Scholar
• Tse SM, Coull BA, Sordillo JE, Datta S, Gold DR. Gender- and age-specific risk factors for wheeze from birth through adolescence. Pediatr Pulmonol. 2015;50(10):955–962. doi:10.1002/ppul.23113
   PubMed Web of Science ®Google Scholar
• Mohammad HR, Belgrave D, Harding KK, et al. Age, sex and the association between skin test responses and IgE titres with asthma. Pediatr Allergy Immunol. 2016;27(3):313–319. doi:10.1111/pai.12534
   PubMed Web of Science ®Google Scholar
• Allinson JP, Afzal S, Çolak Y, et al. Changes in lung function in European adults born between 1884 and 1996 and implications for the diagnosis of lung disease: a cross-sectional analysis of ten population-based studies. Lancet Respir Med. 2022;10(1):83–94. doi:10.1016/S2213-2600(21)00313-1
   PubMed Web of Science ®Google Scholar
• Ministry of education, culture, sports, science and technology in Japan. Available from: https://www.mext.go.jp/index.htm. Accessed November 10, 2021. Japanese.
   Google Scholar
• Yoshihara S, Yoshida T, Kurosaka F, et al. Internet survey of childhood asthma and use of inhaled therapy in the home in Japan. Pediatr Int. 2008;50(4):495–499. doi:10.1111/j.1442-200X.2008.02704.x
   PubMed Web of Science ®Google Scholar