Advanced search
Publication Cover
Journal of Asthma and Allergy Volume 16, 2023 - Issue
Submit an article Journal homepage
310
Views
2
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Characteristics of Severe Non-Eosinophilic Asthma: Analysis of Data from 1075 Patients Included in the FASE-CPHG Study

Laurent Portel1 Service de Pneumologie, Centre Hospitalier Robert Boulin, Libourne, FranceCorrespondence[email protected]
View further author information
,
Caroline Fabry-Vendrand2 Astra Zeneca, Courbevoie, FranceView further author information
,
Nathalie Texier3 Kappa Santé, Paris, FranceView further author information
,
Déborah Schwartz3 Kappa Santé, Paris, FranceView further author information
,
Audrey Capdepon2 Astra Zeneca, Courbevoie, FranceView further author information
,
Gabriel Thabut2 Astra Zeneca, Courbevoie, FranceView further author information
&
Didier Debieuvre4 Service de Pneumologie, Hôpital Émile Muller, Groupe Hospitalier de la Région Mulhouse Sud-Alsace (GHRMSA), Mulhouse, FranceView further author information
 show all
Pages 9-21 | Received 19 May 2022, Accepted 10 Dec 2022, Published online: 04 Jan 2023

References

  • Global Initiative for Asthma (GINA). Pocket guide for asthma management and prevention. A pocket guide for health professionals; 2021. Available from: https://ginasthma.org/pocket-guide-for-asthma-management-and-prevention. Accessed November 2, 2022.
  • Rönnebjerg L, Axelsson M, Kankaanranta H, et al. Severe asthma in a general population study: prevalence and clinical characteristics. J Asthma Allergy. 2021;14:1105–1115. doi:10.2147/JAA.S327659
  • Holguin F, Cardet JC, Chung KF, et al. Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline. Eur Respir J. 2020;55(1):1900588. doi:10.1183/13993003.00588-2019
  • Global Initiative for Asthma (GINA). Diagnosis and management of difficult-to-treat and severe asthma. Difficult-to-treat & severe asthma in adolescent and adult patients. A GINA Pocket Guide for health professionals. V3.0; 2021. Available from: https://ginasthma.org/severeasthma. Accessed November 2, 2022.
  • Bourdin A, Fabry-Vendrand C, Ostinelli J, et al. The burden of severe asthma in France: a case-control study using a medical claims database. J Allergy Clin Immunol Pract. 2019;7(5):1477–1487. doi:10.1016/j.jaip.2018.12.029
  • Gruffydd-Jones K. Unmet needs in asthma. Ther Clin Risk Manag. 2019;15:409–421. doi:10.2147/TCRM.S160327
  • Brusselle GG, Koppelman GH. Biologic Therapies for Severe Asthma. N Engl J Med. 2022;386(2):157–171. doi:10.1056/NEJMra2032506
  • Carr TF, Zeki AA, Kraft M. Eosinophilic and noneosinophilic asthma. Am J Respir Crit Care Med. 2018;197(1):22–37. doi:10.1164/rccm.201611-2232PP
  • Esteban-Gorgojo I, Antolín-Amérigo D, Domínguez-Ortega J, Quirce S. Non-eosinophilic asthma: current perspectives. J Asthma Allergy. 2018;11:267–281. doi:10.2147/JAA.S153097
  • Haute Autorité de Santé (HAS). Asthmes sévères: quels traitements proposer et dans quels cas? Communiqué de presse [Severe asthma: which treatments to offer and in which cases?]; 2018. French. French: https://www.has-sante.fr/jcms/c_2823952/fr/asthmes-severes-quels-traitements-proposer-et-dans-quels-cas. Accessed November 2, 2022.
  • Thomson NC. Novel approaches to the management of noneosinophilic asthma. Ther Adv Respir Dis. 2016;10(3):211‑234. doi:10.1177/1753465816632638
  • Abe Y, Suga Y, Fukushima K, et al. Advances and challenges of antibody therapeutics for severe bronchial asthma. Int J Mol Sci. 2021;23(1):83. doi:10.3390/ijms23010083
  • Portel L, Parrat E, Nocent-Ejnaini C, et al. FASE-CPHG study: a panoramic snapshot of difficult-to-treat, severe asthma in French nonacademic hospitals. ERJ Open Res. 2019;5(4):00069–2019. doi:10.1183/23120541.00069-2019
  • Coëtmeur D, Parrat E, Nocent-Ejnaini C, et al. Activité physique et asthme sévère: résultats de l’étude FASE-CPHG [Physical activity in severe asthma: results of the FASE-CPHG Study]. Rev Mal Respir. 2020;37(4):320–327. French. doi:10.1016/j.rmr.2019.12.004
  • Raherison-Semjen C, Parrat E, Nocent-Eijnani C, et al. CPHG (College of French Non-academic Hospitals). FASE-CPHG Study: identification of asthma phenotypes in the French Severe Asthma Study using cluster analysis. Respir Res. 2021;22(1):136. doi:10.1186/s12931-021-01723-x
  • Douwes J, Gibson P, Pekkanen J, Pearce N. Non-eosinophilic asthma: importance and possible mechanisms. Thorax. 2002;57(7):643–648. doi:10.1136/thorax.57.7.643
  • Heaney LG, Perez de Llano L, Al-Ahmad M, et al. Eosinophilic and noneosinophilic asthma: an expert consensus framework to characterize phenotypes in a global real-life severe asthma cohort. Chest. 2021;160(3):814–830. doi:10.1016/j.chest.2021.04.013
  • Casale TB, Chipps BE, Rosén K, et al. Response to omalizumab using patient enrichment criteria from trials of novel biologics in asthma. Allergy. 2018;73(2):490–497. doi:10.1111/all.13302
  • Yonas MA, Marsland AL, Emeremni CA, Moore CG, Holguin F, Wenzel S. Depressive symptomatology, quality of life and disease control among individuals with well-characterized severe asthma. J Asthma. 2013;50(8):884–890. doi:10.3109/02770903.2013.810750
  • Porsbjerg C, Menzies-Gow A. Co-morbidities in severe asthma: clinical impact and management. Respirology. 2017;22(4):651–661. doi:10.1111/resp.13026
  • Ciprandi G, Schiavetti I, Rindone E, Ricciardolo FLM. The impact of anxiety and depression on outpatients with asthma. Ann Allergy Asthma Immunol. 2015;115(5):408–414. doi:10.1016/j.anai.2015.08.007

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.