Airway Inflammation Before and After Bronchial Thermoplasty in Severe Asthma

References

• Global Initiative for Asthma. Global strategy for asthma management and prevention; 2021. Available from: www.ginasthma.org. Accessed December 1, 2022.
   Google Scholar
• Hekking PP, Wener RR, Amelink M, Zwinderman AH, Bouvy ML, Bel EH. The prevalence of severe refractory asthma. J Allergy Clin Immunol. 2015;135(4):896–902. doi:10.1016/j.jaci.2014.08.042
   PubMed Web of Science ®Google Scholar
• Agache I, Beltran J, Akdis C, et al. Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. A systematic review for the EAACI Guidelines - recommendations on the use of biologicals in severe asthma. Allergy. 2020;75(5):1023–1042. doi:10.1111/all.14221
   PubMed Web of Science ®Google Scholar
• Bel EH, Wenzel SE, Thompson PJ, et al. Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. N Engl J Med. 2014;371(13):1189–1197. doi:10.1056/NEJMoa1403291
   PubMed Web of Science ®Google Scholar
• Ortega HG, Liu MC, Pavord ID, et al. Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med. 2014;371(13):1198–1207. doi:10.1056/NEJMoa1403290
   PubMed Web of Science ®Google Scholar
• Hanania NA, Wenzel S, Rosen K, et al. Exploring the effects of omalizumab in allergic asthma: an analysis of biomarkers in the EXTRA study. Am J Respir Crit Care Med. 2013;187(8):804–811. doi:10.1164/rccm.201208-1414OC
   PubMed Web of Science ®Google Scholar
• Eger K, Kroes JA, Ten A, Bel EH. Long-term therapy response to anti-il-5 biologics in severe asthma-a real-life evaluation. J Allergy Clin Immunol Pract. 2020;9(3):1194–1200. doi:10.1016/j.jaip.2020.10.010
   PubMed Web of Science ®Google Scholar
• Bonta PI, Chanez P, Annema JT, Shah PL, Niven R. Bronchial Thermoplasty in Severe Asthma: best Practice Recommendations from an Expert Panel. Respir Int Rev Thoracic Dis. 2018;95(5):289–300. doi:10.1159/000488291
   Web of Science ®Google Scholar
• Pavord ID, Cox G, Thomson NC, et al. Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma. Am J Respir Crit Care Med. 2007;176(12):1185–1191. doi:10.1164/rccm.200704-571OC
   PubMed Web of Science ®Google Scholar
• Castro M, Rubin AS, Laviolette M, et al. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am J Respir Crit Care Med. 2010;181(2):116–124. doi:10.1164/rccm.200903-0354OC
   PubMed Web of Science ®Google Scholar
• Chupp G, Laviolette M, Cohn L, et al. Long-term outcomes of bronchial thermoplasty in subjects with severe asthma: a comparison of 3-year follow-up results from two prospective multicentre studies. Eur Respir J. 2017;50(2):1700017. doi:10.1183/13993003.00017-2017
   PubMed Web of Science ®Google Scholar
• Cox G, Thomson NC, Rubin AS, et al. Asthma control during the year after bronchial thermoplasty. N Engl J Med. 2007;356(13):1327–1337. doi:10.1056/NEJMoa064707
   PubMed Web of Science ®Google Scholar
• Benayoun L, Druilhe A, Dombret MC, Aubier M, Pretolani M. Airway structural alterations selectively associated with severe asthma. Am J Respir Crit Care Med. 2003;167(10):1360–1368. doi:10.1164/rccm.200209-1030OC
   PubMed Web of Science ®Google Scholar
• Pretolani M, Dombret MC, Thabut G, et al. Reduction of airway smooth muscle mass by bronchial thermoplasty in patients with severe asthma. Am J Respir Crit Care Med. 2014;190(12):1452–1454. doi:10.1164/rccm.201407-1374LE
   PubMed Web of Science ®Google Scholar
• Denner DR, Doeing DC, Hogarth DK, Dugan K, Naureckas ET, White SR. Airway Inflammation after Bronchial Thermoplasty for Severe Asthma. Ann Am Thorac Soc. 2015;12(9):1302–1309. doi:10.1513/AnnalsATS.201502-082OC
   PubMed Web of Science ®Google Scholar
• d’Hooghe JNS, Goorsenberg AWM, Ten Hacken NHT, et al. Airway smooth muscle reduction after bronchial thermoplasty in severe asthma correlates with FEV1. Clin Exp Allergy. 2019;49(4):541–544. doi:10.1111/cea.13365
   PubMed Web of Science ®Google Scholar
• Pretolani M, Bergqvist A, Thabut G, et al. Effectiveness of bronchial thermoplasty in patients with severe refractory asthma: clinical and histopathologic correlations. J Allergy Clin Immunol. 2017;139(4):1176–1185. doi:10.1016/j.jaci.2016.08.009
   PubMed Web of Science ®Google Scholar
• Chakir J, Haj-Salem I, Gras D, et al. Effects of Bronchial Thermoplasty on Airway Smooth Muscle and Collagen Deposition in Asthma. Ann Am Thorac Soc. 2015;12(11):1612–1618. doi:10.1513/AnnalsATS.201504-208OC
   PubMed Web of Science ®Google Scholar
• Goorsenberg AWM, d’Hooghe JNS, Srikanthan K. Bronchial Thermoplasty Induced Airway Smooth Muscle Reduction and Clinical Response in Severe Asthma. The TASMA Randomized Trial. Am J Respir Crit Care Med. 2021;203(2):175–184. doi:10.1164/rccm.201911-2298OC
   PubMed Web of Science ®Google Scholar
• Russell RJ, Brightling CE. Bronchial thermoplasty: what we know, what we don’t know, and what we need to know. Eur Respir J. 2022;59(1):2102018. doi:10.1183/13993003.02018-2021
   PubMed Web of Science ®Google Scholar
• Goorsenberg AM, d’Hooghe JS, de Bruin D, van den Berk IH, Annema J, Bonta P. Bronchial Thermoplasty-Induced Acute Airway Effects Assessed with Optical Coherence Tomography in Severe Asthma. Respir Int Rev Thoracic Dis. 2018;96(6):564–570. doi:10.1159/000491676
   Web of Science ®Google Scholar
• Kirby M, Ohtani K, Lopez Lisbona RM, et al. Bronchial thermoplasty in asthma: 2-year follow-up using optical coherence tomography. Eur Respir J. 2015;46(3):859–862. doi:10.1183/09031936.00016815
   PubMed Web of Science ®Google Scholar
• Ladjemi MZ, Di Candia L, Heddebaut N, et al. Clinical and histopathologic predictors of therapeutic response to bronchial thermoplasty in severe refractory asthma. J Allergy Clin Immunol. 2021;148(5):1227–1235.e6. doi:10.1016/j.jaci.2020.12.642
   PubMed Web of Science ®Google Scholar
• Janssen LJ. Airway smooth muscle as a target in asthma and the beneficial effects of bronchial thermoplasty. J Allergy (Cairo). 2012;2012:593784. doi:10.1155/2012/593784
   PubMedGoogle Scholar
• Zuyderduyn S, Sukkar MB, Fust A, Dhaliwal S, Burgess JK. Treating asthma means treating airway smooth muscle cells. Eur Respir J. 2008;32(2):265–274. doi:10.1183/09031936.00051407
   PubMed Web of Science ®Google Scholar
• Salazar F, Ghaemmaghami AM. Allergen recognition by innate immune cells: critical role of dendritic and epithelial cells. Front Immunol. 2013;4:356. doi:10.3389/fimmu.2013.00356
   PubMed Web of Science ®Google Scholar
• Holtzman MJ, Byers DE, Alexander-Brett J, Wang X. The role of airway epithelial cells and innate immune cells in chronic respiratory disease. Nat Rev Immunol. 2014;14(10):686–698. doi:10.1038/nri3739
   PubMed Web of Science ®Google Scholar
• Bonser LR, Erle DJ. The airway epithelium in asthma. Adv Immunol. 2019;142:1–34.
   PubMed Web of Science ®Google Scholar
• Bousquet J, Mantzouranis E, Cruz AA, et al. Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol. 2010;126(5):926–938. doi:10.1016/j.jaci.2010.07.019
   PubMed Web of Science ®Google Scholar
• Bel EH, Sousa A, Fleming L, et al. Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI). Thorax. 2011;66(10):910–917. doi:10.1136/thx.2010.153643
   PubMed Web of Science ®Google Scholar
• d’Hooghe JN, Eberl S, Annema JT, Bonta PI. Propofol and Remifentanil Sedation for Bronchial Thermoplasty: a Prospective Cohort Trial. Int Rev Thoracic Dis. 2017;93(1):58–64. doi:10.1159/000452478
   Web of Science ®Google Scholar
• Niven R, Aubier M, Bonta P, Puente-Maestu L, Facciolongo N, Ryan D. European consensus meeting/statement on Bronchial Thermoplasty Who? Where? How? Respir Med. 2019;150:161–164. doi:10.1016/j.rmed.2019.02.020
   PubMed Web of Science ®Google Scholar
• Juniper EF, Guyatt GH, Willan A, Griffith LE. Determining a minimal important change in a disease-specific Quality of Life Questionnaire. J Clin Epidemiol. 1994;47(1):81–87. doi:10.1016/0895-4356(94)90036-1
   PubMed Web of Science ®Google Scholar
• Zhou JP, Feng Y, Wang Q, Zhou LN, Wan HY, Li QY. Long-term efficacy and safety of bronchial thermoplasty in patients with moderate-to-severe persistent asthma: a systemic review and meta-analysis. J Asthma. 2015;1:1–7.
   Google Scholar
• Chaudhuri R, Rubin A, Sumino K, et al. Safety and effectiveness of bronchial thermoplasty after 10 years in patients with persistent asthma (BT10+): a follow-up of three randomised controlled trials. Lancet Respir med. 2021;9(5):457–466. doi:10.1016/S2213-2600(20)30408-2
   PubMed Web of Science ®Google Scholar
• Chupp G, Kline JN, Khatri SB, et al. Bronchial Thermoplasty in Severe Asthmatics At 5 Years: the PAS2 Study. Chest. 2021.
   Google Scholar
• Elliot JG, Jones RL, Abramson MJ, et al. Distribution of airway smooth muscle remodelling in asthma: relation to airway inflammation. Respirology. 2015;20(1):66–72. doi:10.1111/resp.12384
   PubMed Web of Science ®Google Scholar
• James AL, Noble PB, Drew SA, et al. Airway smooth muscle proliferation and inflammation in asthma. J Appl Physiol. 2018;125(4):1090–1096. doi:10.1152/japplphysiol.00342.2018
   PubMed Web of Science ®Google Scholar
• Ichikawa T, Panariti A, Audusseau S, et al. Effect of bronchial thermoplasty on structural changes and inflammatory mediators in the airways of subjects with severe asthma. Respir Med. 2019;150:165–172. doi:10.1016/j.rmed.2019.03.005
   PubMed Web of Science ®Google Scholar
• Ravi A, Chowdhury S, Dijkhuis A, Bonta PI, Sterk PJ, Lutter R. Neutrophilic inflammation in asthma and defective epithelial translational control. Eur Respir J. 2019;54(2):1900547. doi:10.1183/13993003.00547-2019
   PubMed Web of Science ®Google Scholar
• Ravi A, Goorsenberg AWM, Dijkhuis A, et al. Metabolic differences between bronchial epithelium from healthy individuals and patients with asthma and the effect of bronchial thermoplasty. J Allergy Clin Immunol. 2021;148(5):1236–1248. doi:10.1016/j.jaci.2020.12.653
   PubMed Web of Science ®Google Scholar
• Papakonstantinou E, Koletsa T, Zhou L, et al. Bronchial thermoplasty in asthma: an exploratory histopathological evaluation in distinct asthma endotypes/phenotypes. Respir Res. 2021;22(1):186. doi:10.1186/s12931-021-01774-0
   PubMed Web of Science ®Google Scholar
• Ano S, Kikuchi N, Matsuyama M, et al. Transcriptome genetic differences between responders and non-responders before bronchial thermoplasty. J Asthma. 2021;58:1–12. doi:10.1080/02770903.2019.1656230
   PubMed Web of Science ®Google Scholar
• Facciolongo N, Bonacini M, Galeone C, et al. Bronchial thermoplasty in severe asthma: a real-world study on efficacy and gene profiling. Allergy Asthma Clin Immunol. 2022;18(1):39. doi:10.1186/s13223-022-00680-4
   PubMed Web of Science ®Google Scholar