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ORIGINAL RESEARCH

Sputum Neurturin Levels in Adult Asthmatic Subjects

ORCID Icon, , , , & ORCID Icon
Pages 889-901 | Received 02 Jun 2023, Accepted 12 Aug 2023, Published online: 31 Aug 2023

References

  • Heuckeroth RO, Enomoto H, Grider JR, et al. Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons. Neuron. 1999;22(2):253–263. doi:10.1016/S0896-6273(00)81087-9
  • Pulleyn LJ, Newton R, Adcock IM, Barnes PJ. TGFbeta1 allele association with asthma severity. Hum Genet. 2001;109(6):623–627. doi:10.1007/s00439-001-0617-y
  • Horger BA, Nishimura MC, Armanini MP, et al. Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. J Neurosci. 1998;18(13):4929–4937. doi:10.1523/JNEUROSCI.18-13-04929.1998
  • Fjord-Larsen L, Johansen JL, Kusk P, et al. Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified neurturin construct. Exp Neurol. 2005;195(1):49–60. doi:10.1016/j.expneurol.2005.03.006
  • Bartus RT, Kordower JH, Johnson EM Jr, et al. Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with alpha-synucleinopathies. Neurobiol Dis. 2015;78:162–171. doi:10.1016/j.nbd.2015.03.023
  • Ruiz-Ferrer M, Torroglosa A, Luzon-Toro B, et al. Novel mutations at RET ligand genes preventing receptor activation are associated to Hirschsprung’s disease. J Mol Med. 2011;89(5):471–480. doi:10.1007/s00109-010-0714-2
  • Widenfalk J, Nosrat C, Tomac A, Westphal H, Hoffer B, Olson L. Neurturin and glial cell line-derived neurotrophic factor receptor-beta (GDNFR-beta), novel proteins related to GDNF and GDNFR-alpha with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in peripheral organs. J Neurosci. 1997;17(21):8506–8519. doi:10.1523/JNEUROSCI.17-21-08506.1997
  • Kabata H, Artis D. Neuro-immune crosstalk and allergic inflammation. J Clin Invest. 2019;129(4):1475–1482. doi:10.1172/JCI124609
  • Lieu T, Kollarik M, Myers AC, Undem BJ. Neurotrophin and GDNF family ligand receptor expression in vagal sensory nerve subtypes innervating the adult Guinea pig respiratory tract. Am J Physiol Lung Cell Mol Physiol. 2011;300(5):L790–L798. doi:10.1152/ajplung.00449.2010
  • Vargas-Leal V, Bruno R, Derfuss T, Krumbholz M, Hohlfeld R, Meinl E. Expression and function of glial cell line-derived neurotrophic factor family ligands and their receptors on human immune cells. J Immunol. 2005;175(4):2301–2308. doi:10.4049/jimmunol.175.4.2301
  • Michel T, Theresine M, Poli A, et al. Increased Th2 cytokine secretion, eosinophilic airway inflammation, and airway hyperresponsiveness in neurturin-deficient mice. J Immunol. 2011;186(11):6497–6504. doi:10.4049/jimmunol.1001673
  • Mauffray M, Domingues O, Hentges F, Zimmer J, Hanau D, Michel T. Neurturin influences inflammatory responses and airway remodeling in different mouse asthma models. J Immunol. 2015;194(4):1423–1433. doi:10.4049/jimmunol.1402496
  • American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986. Am Rev Respir Dis. 1987;136(1):225–244. doi:10.1164/ajrccm/136.1.225
  • Ichinose M, Sugiura H, Nagase H, et al. Japanese guidelines for adult asthma 2017. Allergol Int. 2017;66(2):163–189. doi:10.1016/j.alit.2016.12.005
  • Pizzichini E, Pizzichini MM, Efthimiadis A, et al. Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. Am J Respir Crit Care Med. 1996;154(2 Pt 1):308–317. doi:10.1164/ajrccm.154.2.8756799
  • Hastie AT, Mauger DT, Denlinger LC, et al. Mixed sputum granulocyte longitudinal impact on lung function in the severe asthma research program. Am J Respir Crit Care Med. 2021;203(7):882–892. doi:10.1164/rccm.202009-3713OC
  • Liu J, Huang X, Cao X, Feng X, Wang X. Serum biomarker analysis in patients with premature ovarian insufficiency. Cytokine. 2020;126:154876. doi:10.1016/j.cyto.2019.154876
  • Crapo RO, Hankinson JL, Irvin C, et al. Standardization of spirometry, 1994 Update. American Thoracic Society. Am J Respir Crit Care Med. 1995;152(3):1107–1136. doi:10.1164/ajrccm.152.3.7663792
  • Dweik RA, Boggs PB, Erzurum SC, et al. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med. 2011;184(5):602–615. doi:10.1164/rccm.9120-11ST
  • Sato S, Saito J, Sato Y, et al. Clinical usefulness of fractional exhaled nitric oxide for diagnosing prolonged cough. Respir Med. 2008;102(10):1452–1459. doi:10.1016/j.rmed.2008.04.018
  • Nathan RA, Sorkness CA, Kosinski M, et al. Development of the asthma control test: a survey for assessing asthma control. J Allergy Clin Immunol. 2004;113(1):59–65. doi:10.1016/j.jaci.2003.09.008
  • Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, 2023. Global Initiative for Asthma; 2023.
  • Morel L, Domingues O, Zimmer J, Michel T. Revisiting the role of neurotrophic factors in inflammation. Cells. 2020;9(4):865. doi:10.3390/cells9040865
  • Connolly E, Morgan DJ, Franklin M, et al. Neurturin regulates the lung-resident macrophage inflammatory response to viral infection. Life Sci Alliance. 2020;3(12):e202000780. doi:10.26508/lsa.202000780
  • Abdo M, Pedersen F, Kirsten AM, et al. Longitudinal impact of sputum inflammatory phenotypes on small airway dysfunction and disease outcomes in asthma. J Allergy Clin Immunol Pract. 2022;10(6):1545–1553 e2. doi:10.1016/j.jaip.2022.02.020
  • Atkinson JJ, Senior RM. Matrix metalloproteinase-9 in lung remodeling. Am J Respir Cell Mol Biol. 2003;28(1):12–24. doi:10.1165/rcmb.2002-0166TR
  • Wong KL, Tai JJ, Wong WC, et al. Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets. Blood. 2011;118(5):e16–e31. doi:10.1182/blood-2010-12-326355
  • Corry DB, Kiss A, Song LZ, et al. Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines. FASEB J. 2004;18(9):995–997. doi:10.1096/fj.03-1412fje
  • Bhallamudi S, Roos BB, Teske JJ, et al. Glial-derived neurotrophic factor in human airway smooth muscle. J Cell Physiol. 2021;236(12):8184–8196. doi:10.1002/jcp.30489
  • Teague WG, Phillips BR, Fahy JV, et al. Baseline features of the Severe Asthma Research Program (SARP III) cohort: differences with age. J Allergy Clin Immunol Pract. 2018;6(2):545–554 e4. doi:10.1016/j.jaip.2017.05.032
  • Soma T, Nagata M. Immunosenescence, inflammaging, and lung senescence in asthma in the elderly. Biomolecules. 2022;12(10):1456. doi:10.3390/biom12101456