1,435
Views
136
CrossRef citations to date
0
Altmetric
Review

Wheat allergy: diagnosis and management

Pages 13-25 | Published online: 29 Jan 2016

References

  • FasanoASaponeAZevallosVSchuppanDNonceliac gluten sensitivityGastroenterology201514861195120425583468
  • CianferoniASpergelJMFood allergy: review, classification and diagnosisAllergol Int200958445746619847094
  • CianferoniAKhullarKSaltzmanROral food challenge to wheat: a near-fatal anaphylaxis and review of 93 food challenges in childrenWorld Allergy Organ J2013611423965733
  • CianferoniAMuraroAFood-induced anaphylaxisImmunol Allergy Clin North Am201232116519522244239
  • SalcedoGQuirceSDiaz-PeralesAWheat allergens associated with Baker’s asthmaJ Investig Allergol Clin Immunol20112128192
  • NovembreECianferoniABernardiniREpidemiology of insect venom sensitivity in children and its correlation to clinical and atopic featuresClin Exp Allergy19982878348389720817
  • PooleJABarrigaKLeungDYTiming of initial exposure to cereal grains and the risk of wheat allergyPediatrics200611762175218216740862
  • VenterCPereiraBGrundyJClaytonCBArshadSHDeanTPrevalence of sensitization reported and objectively assessed food hypersensitivity amongst six-year-old children: a population-based studyPediatr Allergy Immunol200617535636316846454
  • VenterCPereiraBGrundyJIncidence of parentally reported and clinically diagnosed food hypersensitivity in the first year of lifeJ Allergy Clin Immunol200611751118112416675341
  • VenterCPereiraBVoigtKComparison of open and double-blind placebo-controlled food challenges in diagnosis of food hypersensitivity amongst childrenJ Hum Nutr Diet200720656557918001378
  • VenterCPereiraBVoigtKPrevalence and cumulative incidence of food hypersensitivity in the first 3 years of lifeAllergy200863335435918053008
  • KeetCAMatsuiECDhillonGLenehanPPaterakisMWoodRAThe natural history of wheat allergyAnn Allergy Asthma Immunol2009102541041519492663
  • AiharaYKotoyoriTTakahashiYOsunaHOhnumaSIkezawaZThe necessity for dual food intake to provoke food-dependent exercise-induced anaphylaxis (FEIAn): a case report of FEIAn with simultaneous intake of wheat and umeboshiJ Allergy Clin Immunol200110761100110511398092
  • PourpakZGhojezadehLMansouriMMozaffariHFarhoudiAWheat anaphylaxis in childrenImmunol Invest200736217518217365018
  • ScherfKABrockowKBiedermannTKoehlerPWieserHWheat-dependent exercise-induced anaphylaxisClin Exp Allergy Epub2015918
  • Du ToitGFood-dependent exercise-induced anaphylaxis in childhoodPediatr Allergy Immunol200718545546317617816
  • WiszniewskaMNowakowska-SwirtaEPalczynskiCWalusiak-SkorupaJDiagnosing of bakers’ respiratory allergy: is specific inhalation challenge test essential?Allergy Asthma Proc201132211111821439164
  • QuirceSDiaz-PeralesADiagnosis and management of grain-induced asthmaAllergy Asthma Immunol Res20135634835624179680
  • SampsonHAFood allergy. Part 1: immunopathogenesis and clinical disordersJ Allergy Clin Immunol19991035 Pt 171772810329801
  • LeeLABurksAWFood allergies: prevalence, molecular characterization, and treatment/prevention strategiesAnnu Rev Nutr20062653956516602930
  • ChehadeMMayerLOral tolerance and its relation to food hypersensitivitiesJ Allergy Clin Immunol2005115131215637539
  • HeymanMSymposium on ‘dietary influences on mucosal immunity’. How dietary antigens access the mucosal immune systemProc Nutr Soc200160441942612069393
  • IwasakiAMucosal dendritic cellsAnnu Rev Immunol20072538141817378762
  • DahanSRoth-WalterFArnaboldiPAgarwalSMayerLEpithelia: lymphocyte interactions in the gutImmunol Rev200721524325317291293
  • MowatAMAnatomical basis of tolerance and immunity to intestinal antigensNat Rev Immunol20033433134112669023
  • LackGEpidemiologic risks for food allergyJ Allergy Clin Immunol200812161331133618539191
  • RomagnaniPAnnunziatoFPiccinniMPMaggiERomagnaniSTh1/Th2 cells, their associated molecules and role in pathophysiologyEur Cytokine Netw200011351051111203198
  • RadauerCBreitenederHEvolutionary biology of plant food allergensJ Allergy Clin Immunol2007120351852517689599
  • PastorelloEAFarioliLContiAWheat IgE-mediated food allergy in European patients: alpha-amylase inhibitors, lipid transfer proteins and low-molecular-weight glutenins. Allergenic molecules recognized by double-blind, placebo-controlled food challengeInt Arch Allergy Immunol20071441102217496422
  • PalosuoKAleniusHVarjonenEA novel wheat gliadin as a cause of exercise-induced anaphylaxisJ Allergy Clin Immunol19991035 Pt 191291710329828
  • MoritaEMatsuoHMiharaSMorimotoKSavageAWTathamASFast omega-gliadin is a major allergen in wheat-dependent exercise-induced anaphylaxisJ Dermatol Sci20033329910414581135
  • PahrSSelbRWeberMBiochemical, biophysical and IgE-epitope characterization of the wheat food allergen, Tri a 37PloS one2014911e11148325368998
  • PahrSConstantinCPapadopoulosNGalpha-Purothionin, a new wheat allergen associated with severe allergyJ Allergy Clin Immunol201313241000100323810762
  • PahrSConstantinCMariAMolecular characterization of wheat allergens specifically recognized by patients suffering from wheat-induced respiratory allergyClin Exp Allergy201242459760922417217
  • PalacinAQuirceSArmentiaAWheat lipid transfer protein is a major allergen associated with baker’s asthmaJ Allergy Clin Immunol200712051132113817716720
  • PastorelloEAFarioliLStafylarakiCWheat-dependent exercise-induced anaphylaxis caused by a lipid transfer protein and not by omega-5 gliadinAnn Allergy Asthma Immunol2014112438638724507829
  • Sánchez-MongeRGarcía-CasadoGLópez-OtínCArmentiaASalcedoGWheat flour peroxidase is a prominent allergen associated with baker’s asthmaClin Exp Allergy19972710113011379383252
  • YamashitaHNanbaYOnishiMKimotoMHiemoriMTsujiHIdentification of a wheat allergen, Tri a Bd 36K, as a peroxidaseBiosci Biotechnol Biochem200266112487249012506994
  • KobrehelKWongJHBaloghAKissFYeeBCBuchananBBSpecific reduction of wheat storage proteins by thioredoxin hPlant Physiol199299391992411538180
  • WeichelMGlaserAGBallmer-WeberBKSchmid-GrendelmeierPCrameriRWheat and maize thioredoxins: a novel cross-reactive cereal allergen family related to baker’s asthmaJ Allergy Clin Immunol2006117367668116522470
  • WeichelMVergoossenNJBonomiSScreening the allergenic repertoires of wheat and maize with sera from double-blind, placebo-controlled food challenge positive patientsAllergy200661112813516364168
  • ConstantinCQuirceSGroteMMolecular and immunological characterization of a wheat serine proteinase inhibitor as a novel allergen in baker’s asthmaJ Immunol2008180117451746018490745
  • ConstantinCQuirceSPoorafsharMMicro-arrayed wheat seed and grass pollen allergens for component-resolved diagnosisAllergy20096471030103719210348
  • LehtoMAiraksinenLPuustinenAThaumatin-like protein and baker’s respiratory allergyAnn Allergy Asthma Immunol2010104213914620306817
  • BittnerCGrassauBFrenzelKBaurXIdentification of wheat gliadins as an allergen family related to baker’s asthmaJ Allergy Clin Immunol2008121374474918036646
  • SanderIRaulf-HeimsothMDuserMFlaggeACzupponABBaurXDifferentiation between cosensitization and cross-reactivity in wheat flour and grass pollen-sensitized subjectsInt Arch Allergy Immunol199711243783859104794
  • JonesSMMagnolfiCFCookeSKSampsonHAImmunologic cross-reactivity among cereal grains and grasses in children with food hypersensitivityJ Allergy Clin Immunol19959633413517560636
  • NiggemannBSielaffBBeyerKBinderCWahnUOutcome of double-blind, placebo-controlled food challenge tests in 107 children with atopic dermatitisClin Exp Allergy1999291919610051707
  • NiggemannBRolinck-WerninghausCMehlABinderCZiegertMBeyerKControlled oral food challenges in children – when indicated, when superfluous?Allergy200560786587015932374
  • PerryTTMatsuiECConover-WalkerMKWoodRARisk of oral food challengesJ Allergy Clin Immunol200411451164116815536426
  • ReibelSRohrCZiegertMSommerfeldCWahnUNiggemannBWhat safety measures need to be taken in oral food challenges in children?Allergy2000551094094411030374
  • SiracusaMCSaenzSAHillDATSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammationNature2011477736322923321841801
  • GonsalvesNFood allergies and eosinophilic gastrointestinal illnessGastroenterol Clin North Am20073617591vi17472876
  • FujitaHOsunaHKanbaraTInomataNIkezawaZ[Wheat anaphylaxis enhanced by administration of acetylsalicylic acid or by exercise]Arerugi2005541012031207 Japanese16407667
  • BrockowKKneisslDValentiniLUsing a gluten oral food challenge protocol to improve diagnosis of wheat-dependent exercise-induced anaphylaxisJ Allergy Clin Immunol2015135497798425269870
  • van KampenVRabsteinSSanderIPrediction of challenge test results by flour-specific IgE and skin prick test in symptomatic bakersAllergy200863789790218588556
  • HoubaRHeederikDDoekesGWheat sensitization and work-related symptoms in the baking industry are preventable. An epidemiologic studyAm J Respir Crit Care Med19981585 Pt 1149915039817699
  • HoubaRVan RunPHeederikDDoekesGWheat antigen exposure assessment for epidemiological studies in bakeries using personal dust sampling and inhibition ELISAClin Exp Allergy19962621541638835122
  • MeijsterTTielemansEde PaterNHeederikDModelling exposure in flour processing sectors in the Netherlands: a baseline measurement in the context of an intervention programAnn Occup Hyg200751329330417369619
  • MergetRHegerMGlobischAQuantitative bronchial challenge tests with wheat flour dust administered by spinhaler: comparison with aqueous wheat flour extract inhalationJ Allergy Clin Immunol199710021992079275141
  • SanderIRihsHPDoekesGComponent-resolved diagnosis of baker’s allergy based on specific IgE to recombinant wheat flour proteinsJ Allergy Clin Immunol201513561529153725576081
  • OlivieriMBiscardoCAPalazzoPWheat IgE profiling and wheat IgE levels in bakers with allergic occupational phenotypesOccup Environ Med201370961762223685986
  • van RhijnBDVlieg-BoerstraBJVersteegSAEvaluation of allergen-microarray-guided dietary intervention as treatment of eosinophilic esophagitisJ Allergy Clin Immunol201513641095109725935104
  • JonesSMBurksAWDupontCState of the art on food allergen immunotherapy: oral, sublingual, and epicutaneousJ Allergy Clin Immunol2014133231832324636471
  • VarshneyPJonesSMScurlockAMA randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic responseJ Allergy Clin Immunol2011127365466021377034
  • SkripakJMNashSDRowleyHA randomized, double-blind, placebo-controlled study of milk oral immunotherapy for cow’s milk allergyJ Allergy Clin Immunol200812261154116018951617
  • BurksAWJonesSMWoodRAOral immunotherapy for treatment of egg allergy in childrenN Engl J Med2012367323324322808958
  • ThyagarajanAVarshneyPJonesSMPeanut oral immunotherapy (OIT) is not ready for clinical useJ Allergy Clin Immunol20101261313220620564
  • KalachNSoulainesPde BoissieuDDupontCA pilot study of the usefulness and safety of a ready-to-use atopy patch test (Diallertest) versus a comparator (Finn Chamber) during cow’s milk allergy in childrenJ Allergy Clin Immunol200511661321132616337466
  • DupontCKalachNSoulainesPLegoue-MorillonSPiloquetHBenhamouPHCow’s milk epicutaneous immunotherapy in children: a pilot trial of safety, acceptability, and impact on allergic reactivityJ Allergy Clin Immunol201012551165116720451043
  • CrivellaroMSennaGMarcerGPassalacquaGImmunological treatments for occupational allergyInt J Immunopathol Pharmacol201326357958424067454
  • ArmentiaAMartin-SantosJMQuinteroABakers’ asthma: prevalence and evaluation of immunotherapy with a wheat flour extractAnn Allergy19906542652722221484
  • CirlaAMLorenziniRACirlaPERecupero professionale di panificatiori allergici mediante vaccino verso farina di frumento [Specific immunotherapy and relocation in occupational allergic bakers]Giornale italiano di medicina del lavoro ed ergonomia2007293 Suppl443445 Italian18409768
  • ArmentiaAArranzMMartinJMEvaluation of immune complexes after immunotherapy with wheat flour in bakers’ asthmaAnn Allergy19926954414441456487
  • OlivieriMBiscardoCATurriSPerbelliniLOmalizumab in persistent severe bakers’ asthmaAllergy200863679079118445199
  • DeBrosseCWRothenbergMEAllergy and eosinophil-associated gastrointestinal disorders (EGID)Curr Opin Immunol200820670370818721876
  • FurutaGTForbesDBoeyCEosinophilic gastrointestinal diseases (EGIDs)J Pediatr Gastroenterol Nutr200847223423818664881
  • StraumannAIdiopathic eosinophilic gastrointestinal diseases in adultsBest Pract Res Clin Gastroenterol200822348149618492567
  • StraumannASimonHUEosinophilic esophagitis: escalating epidemiology?J Allergy Clin Immunol2005115241841915696105
  • CherianSSmithNMForbesDARapidly increasing prevalence of eosinophilic oesophagitis in Western AustraliaArch Dis Child200691121000100416877474
  • van RhijnBDVerheijJSmoutAJBredenoordAJRapidly increasing incidence of eosinophilic esophagitis in a large cohortNeurogastroenterol Motil2013251475222963642
  • HruzPStraumannABussmannCEscalating incidence of eosinophilic esophagitis: a 20-year prospective, population-based study in Olten County, SwitzerlandJ Allergy Clin Immunol201112861349135022019091
  • SpergelJMBrown-WhitehornTFBeausoleilJL14 years of eosinophilic esophagitis: clinical features and prognosisJ Pediatr Gastroenterol Nutr2009481303619172120
  • StraumannAEosinophilic esophagitis: a bulk of mysteriesDig Dis20133116923797116
  • LiacourasCAFurutaGTHiranoIEosinophilic esophagitis: updated consensus recommendations for children and adultsJ Allergy Clin Immunol2011128132021477849
  • JensenETMartinCFKappelmanMDDellonESPrevalence of Eosinophilic Gastritis, Gastroenteritis, and Colitis: Estimates From a National Administrative DatabaseJ Pediatr Gastroenterol Nutr Epub2015520
  • CaldwellJMCollinsMHStuckeEMHistologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptomeJ Allergy Clin Immunol201413451114112425234644
  • KoHMMorottiRAYershovOChehadeMEosinophilic gastritis in children: clinicopathological correlation, disease course, and response to therapyAm J Gastroenterol201410981277128524957155
  • PrussinCEosinophilic gastroenteritis and related eosinophilic disordersGastroenterol Clin North Am201443231732724813518
  • BlanchardCMinglerMKVicarioMIL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoidsJ Allergy Clin Immunol200712061292130018073124
  • BlanchardCWangNStringerKFEotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitisJ Clin Invest2006116253654716453027
  • JyonouchiSSmithCLSarettaFInvariant natural killer T cells in children with eosinophilic esophagitisClin Exp Allergy2014441586824118614
  • NotiMWojnoEDKimBSThymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitisNat Med20131981005101323872715
  • SherrillJDGaoPSStuckeEMVariants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitisJ Allergy Clin Immunol2010126116016520620568
  • RothenbergMESpergelJMSherrillJDCommon variants at 5q22 associate with pediatric eosinophilic esophagitisNat Genet201042428929120208534
  • KottyanLCDavisBPSherrillJDGenome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic diseaseNat Genet201446889590025017104
  • NoelRJPutnamPERothenbergMEEosinophilic esophagitisN Engl J Med2004351994094115329438
  • SherrillJDRothenbergMEGenetic and epigenetic underpinnings of eosinophilic esophagitisGastroenterol Clin North Am201443226928024813515
  • FranciosiJPTamVLiacourasCASpergelJMA case-control study of sociodemographic and geographic characteristics of 335 children with eosinophilic esophagitisClin Gastroenterol Hepatol20097441541919118642
  • SleimanPMWangMLCianferoniAGWAS identifies four novel eosinophilic esophagitis lociNat Commun20145559325407941
  • SpergelJMRothenbergMECollinsMHReslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trialJ Allergy Clin Immunol2012129245646322206777
  • SherrillJDKcKWuDDesmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitisMucosal immunology20147371872924220297
  • KellyKJLazenbyAJRowePCYardleyJHPermanJASampsonHAEosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formulaGastroenterology19951095150315127557132
  • KagalwallaAFSentongoTARitzSEffect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitisClin Gastroenterol Hepatol2006491097110216860614
  • SpergelJMBrown-WhitehornTFCianferoniAIdentification of causative foods in children with eosinophilic esophagitis treated with an elimination dietJ Allergy Clin Immunol2012130246146722743304
  • ClaytonFFangJCGleichGJEosinophilic esophagitis in adults is associated with IgG4 and not mediated by IgEGastroenterology2014147360260924907494
  • LucendoAJAriasATeniasJMRelation between eosinophilic esophagitis and oral immunotherapy for food allergy: a systematic review with meta-analysisAnn Allergy Asthma Immunol2014113662462925216976
  • MaggadottirSMHillDARuymannKResolution of acute IgE-mediated allergy with development of eosinophilic esophagitis triggered by the same foodJ Allergy Clin Immunol201413351487148924636092
  • SpergelJMEosinophilic esophagitis in adults and children: evidence for a food allergy component in many patientsCurr Opin Allergy Clin Immunol20077327427817489048
  • GonsalvesNYangGYDoerflerBRitzSDittoAMHiranoIElimination diet effectively treats eosinophilic esophagitis in adults; food reintroduction identifies causative factorsGastroenterology201214271451145922391333
  • Molina-InfanteJAriasABarrioJRodriguez-SanchezJSanchez-CazalillaMLucendoAJFour-food group elimination diet for adult eosinophilic esophagitis: A prospective multicenter studyJ Allergy Clin Immunol201413451093109925174868
  • ErwinEATripathiAOgboguPUIgE Antibody Detection and Component Analysis in Patients with Eosinophilic EsophagitisJ Allergy Clin Immunol Pract Epub2015619
  • FurutaGTLiacourasCACollinsMHEosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatmentGastroenterology200713341342136317919504
  • Menard-KatcherPMarksKLLiacourasCASpergelJMYangYXFalkGWThe natural history of eosinophilic oesophagitis in the transition from childhood to adulthoodAliment Pharmacol Ther201337111412123121227
  • MervesJMuirAModayur ChandramouleeswaranPCianferoniAWangMLSpergelJMEosinophilic esophagitisAnn Allergy Asthma Immunol2014112539740324566295
  • LiacourasCASpergelJGoberLMEosinophilic esophagitis: clinical presentation in childrenGastroenterol Clin North Am201443221922924813511
  • LiacourasCASpergelJMRuchelliEEosinophilic esophagitis: a 10-year experience in 381 childrenClin Gastroenterol Hepatol20053121198120616361045
  • AcevesSSBastianJFNewburyRODohilROral viscous budesonide: a potential new therapy for eosinophilic esophagitis in childrenAm J Gastroenterol2007102102271227917581266
  • ButzBKWenTGleichGJEfficacy, dose reduction, and resistance to high-dose fluticasone in patients with eosinophilic esophagitisGastroenterology2014147232433324768678
  • GreenhawtMAcevesSSSpergelJMRothenbergMEThe management of eosinophilic esophagitisJ Allergy Clin Immunol Pract20131433234024565538
  • Sanchez-GarciaSRodriguez Del RioPEscuderoCMartinez-GomezMJIbanezMDPossible eosinophilic esophagitis induced by milk oral immunotherapyJ Allergy Clin Immunol201212941155115722236725
  • TanACKruimelJWNaberTHEosinophilic gastroenteritis treated with non-enteric-coated budesonide tabletsEur J Gastroenterol Hepatol200113442542711338074
  • AmmouryRFRosenmanMBRoettcherDGuptaSKIncidental gastric eosinophils in patients with eosinophilic esophagitis: do they matter?J Pediatr Gastroenterol Nutr201051672372620601904
  • PalosuoKVarjonenEKekkiOMWheat omega-5 gliadin is a major allergen in children with immediate allergy to ingested wheatJ Allergy Clin Immunol2001108463463811590393
  • EbisawaMShibataRSatoSBorresMPItoKClinical utility of IgE antibodies to omega-5 gliadin in the diagnosis of wheat allergy: a pediatric multicenter challenge studyInt Arch Allergy Immunol20121581717622212744
  • SampsonHAUtility of food-specific IgE concentrations in predicting symptomatic food allergyJ Allergy Clin Immunol2001107589189611344358
  • MatsuoHDahlstromJTanakaASensitivity and specificity of recombinant omega-5 gliadin-specific IgE measurement for the diagnosis of wheat-dependent exercise-induced anaphylaxisAllergy200863223323618186814