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Review

Optimizing transfusion strategies in damage control resuscitation: current insights

, &
Pages 117-133 | Published online: 20 Aug 2018

References

  • PohlmanTHWalshMAversaJHutchisonEMOlsenKPLawrence ReedRDamage control resuscitationBlood Rev201529425126225631636
  • ChangRCardenasJCWadeCEHolcombJBAdvances in the understanding of trauma-induced coagulopathyBlood201612881043104927381903
  • MacLeodJBWinklerAMMcCoyCCHillyerCDShazBHEarly trauma induced coagulopathy (ETIC): prevalence across the injury spectrumInjury201445591091524438827
  • SchochlHSchlimpCJVoelckelWPotential value of pharmacological protocols in traumaCurr Opin Anaesthesiol201326222122923321555
  • OshiroAYanagidaYGandoSHenzanNTakahashiIMakiseHHemostasis during the early stages of trauma: comparison with disseminated intravascular coagulationCrit Care2014182R6124708802
  • ChangRHolcombJBOptimal fluid therapy for traumatic hemorrhagic shockCrit Care Clin2017331153627894494
  • RahbarEFoxEEdel JuncoDJEarly resuscitation intensity as a surrogate for bleeding severity and early mortality in the PROMMTT studyJ Trauma Acute Care Surg2013751 Suppl 1S162323778506
  • RahbarMHdel JuncoDJHuangHA latent class model for defining severe hemorrhage: experience from the PROMMTT studyJ Trauma Acute Care Surg2013751 Suppl 1S828823778516
  • OldroydJCVenardosKMAokiNJImproving outcomes for hospital patients with critical bleeding requiring massive transfusion: the Australian and New Zealand Massive Transfusion Registry study methodologyBMC Res Notes20169145727716381
  • LeviMFriesDGombotzHPrevention and treatment of coagulopathy in patients receiving massive transfusionsVox Sang2011101215417421749403
  • SavageSAZarzaurBLCroceMAFabianTCRedefining massive transfusion when every second countsJ Trauma Acute Care Surg201374239640023354230
  • BrohiKCohenMJGanterMTAcute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysisJ Trauma20086451211121718469643
  • BrohiKSinghJHeronMCoatsTAcute traumatic coagulopathyJ Trauma20035461127113012813333
  • HessJRDuttonRBHolcombJBScaleaTMGiving plasma at a 1:1 ratio with red cells in resuscitation: who might benefit?Transfusion20084881763176518482190
  • HolcombJBJenkinsDRheePDamage control resuscitation: directly addressing the early coagulopathy of traumaJ Trauma200762230731017297317
  • McLaughlinDFNilesSESalinasJA predictive model for massive transfusion in combat casualty patientsJ Trauma2008642 SupplS57S6318376173
  • NilesSEMcLaughlinDFPerkinsJGIncreased mortality associated with the early coagulopathy of trauma in combat casualtiesJ Trauma20086461459146318545109
  • MesarTLarentzakisADzikWChangYVelmahosGYehDDAssociation between ratio of fresh frozen plasma to red blood cells during massive transfusion and survival among patients without traumatic injuryJAMA Surg2017152657458028273299
  • FarooqNGaliatsatosPAulakhJKHigginsCMartinezAMassive transfusion practice in non-trauma related hemorrhagic shockJ Crit Care201843656928846895
  • American College of Obstetricians and Gynecologists Committee on Patient Safety and Quality ImprovementCommittee Opinion No. 590: preparing for clinical emergencies in obstetrics and gynecologyObstet Gynecol2014123372272524553170
  • WeisbrodABSheppardFRChernofskyMREmergent management of postpartum hemorrhage for the general and acute care surgeonWorld J Emerg Surg200944319939251
  • MatsumotoTNogamiKShimaMSimultaneous measurement of thrombin and plasmin generation to assess the interplay between coagulation and fibrinolysisThromb Haemost2013110476176824072166
  • HoffmanMMonroeDM3rdA cell-based model of hemostasisThromb Haemost200185695896511434702
  • MonroeDMHoffmanMRobertsHRPlatelets and thrombin generationArterioscler Thromb Vasc Biol20022291381138912231555
  • WolbergASThrombin generation and fibrin clot structureBlood Rev200721313114217208341
  • HuangCCShihCCLiuTYLeePYAssessing the viscoelastic properties of thrombus using a solid-sphere-based instantaneous force approachUltrasound Med Biol201137101722173321821355
  • Van de WouwerMCollenDConwayEMThrombomodulin-protein C-EPCR system: integrated to regulate coagulation and inflammationArterioscler Thromb Vasc Biol20042481374138315178554
  • WoodJPElleryPEMaroneySAMastAEBiology of tissue factor pathway inhibitorBlood2014123192934294324620349
  • MastAETissue factor pathway inhibitor: multiple anticoagulant activities for a single proteinArterioscler Thromb Vasc Biol201636191426603155
  • MaroneySAMastAENew insights into the biology of tissue factor pathway inhibitorJ Thromb Haemost201513Suppl 1S200S20726149025
  • GandoSOtomoYLocal hemostasis, immunothrombosis, and systemic disseminated intravascular coagulation in trauma and traumatic shockCrit Care2015197225886801
  • MartinFAMurphyRPCumminsPMThrombomodulin and the vascular endothelium: insights into functional, regulatory, and therapeutic aspectsAm J Physiol Heart Circ Physiol201330412H1585H159723604713
  • ChristiaansSCWagenerBMEsmonCTPittetJFProtein C and acute inflammation: a clinical and biological perspectiveAm J Physiol Lung Cell Mol Physiol20133057L455L46623911436
  • Schedin-WeissSRichardBOlsonSTKinetic evidence that allosteric activation of antithrombin by heparin is mediated by two sequential conformational changesArch Biochem Biophys2010504216917620816747
  • LevyJHSniecinskiRMWelsbyIJLeviMAntithrombin: anti-inflammatory properties and clinical applicationsThromb Haemost2016115471272826676884
  • CampbellWDLazouraEOkadaNOkadaHInactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase NMicrobiol Immunol200246213113411939578
  • MylesTNishimuraTYunTHThrombin activatable fibrinolysis inhibitor, a potential regulator of vascular inflammationJ Biol Chem200327851510595106714525995
  • NishimuraTMylesTPiliponskyAMKaoPNBerryGJLeungLLThrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivoBlood200710951992199717105819
  • WengHBLiSEarly changes of plasma angiopoietin-2 in patients with multiple traumaWorld J Emerg Med20112428729025215025
  • DalyCQianXCastanaroCAngiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactorSci Rep20188150529323190
  • Lomas-NeiraJVenetFChungCSThakkarRHeffernanDAyalaANeutrophil-endothelial interactions mediate angiopoietin-2-associated pulmonary endothelial cell dysfunction in indirect acute lung injury in miceAm J Respir Cell Mol Biol201450119320023980650
  • HughesDPMarronMBBrindleNPThe antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2Circ Res200392663063612609966
  • TadrosAHughesDPDunmoreBJBrindleNPABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1Blood2003102134407440912933576
  • TerpstraMLAmanJvan Nieuw AmerongenGPGroeneveldABPlasma biomarkers for acute respiratory distress syndrome: a systematic review and meta-analysis*Crit Care Med201442369170024158164
  • ZinterMSSpicerAOrwollBOPlasma angiopoietin-2 outperforms other markers of endothelial injury in prognosticating pediatric ARDS mortalityAm J Physiol Lung Cell Mol Physiol20163103L224L23126660787
  • HerreroRSanchezGLorenteJANew insights into the mechanisms of pulmonary edema in acute lung injuryAnn Transl Med2018623229430449
  • HajjarianZTripathiMMNadkarniSKOptical Thromboelastography to evaluate whole blood coagulationJ Biophotonics20158537238124700701
  • JohanssonPICoagulation monitoring of the bleeding traumatized patientCurr Opin Anaesthesiol201225223524122193152
  • WeederPDPorteRJLismanTHemostasis in liver disease: implications of new concepts for perioperative managementTransfus Med Rev201428310711324721432
  • WeiselJWBiophysics. Enigmas of blood clot elasticityScience2008320587545645718436761
  • JohanssonPIStissingTBochsenLOstrowskiSRThrombelastography and tromboelastometry in assessing coagulopathy in traumaScand J Trauma Resusc Emerg Med2009174519775458
  • JohanssonPISvendsenMSSaladoJBochsenLKristensenATInvestigation of the thrombin-generating capacity, evaluated by thrombogram, and clot formation evaluated by thrombelastography of platelets stored in the blood bank for up to 7 daysVox Sang200894211311818067490
  • KawasakiJKatoriNKodakaMMiyaoHTanakaKAElectron microscopic evaluations of clot morphology during thrombelastographyAnesth Analg20049951440144415502045
  • GonzalezEMooreEEMooreHBManagement of trauma-induced coagulopathy with thrombelastographyCrit Care Clin201733111913427894492
  • GonzalezEMooreEEMooreHBGoal-directed hemostatic resuscitation of trauma-induced coagulopathy: a pragmatic randomized clinical trial comparing a viscoelastic assay to conventional coagulation assaysAnn Surg201626361051105926720428
  • HarrJNMooreEEChinTLViscoelastic hemostatic fibrinogen assays detect fibrinolysis earlyEur J Trauma Emerg Surg2015411495626038165
  • MooreEEMooreHBGonzalezEPostinjury fibrinolysis shutdown: rationale for selective tranexamic acidJ Trauma Acute Care Surg2015786 Suppl 1S65S6926002266
  • WadaTCoagulofibrinolytic changes in patients with post-cardiac arrest syndromeFront Med (Lausanne)2017415629034235
  • RamseyMTFabianTCShahanCPA prospective study of platelet function in trauma patientsJ Trauma Acute Care Surg201680572673226895088
  • DavisPKMusunuruHWalshMPlatelet dysfunction is an early marker for traumatic brain injury-induced coagulopathyNeurocrit Care201318220120822847397
  • WindelovNASorensenAMPernerAPlatelet aggregation following trauma: a prospective studyBlood Coagul Fibrinolysis2014251677323945060
  • WohlauerMVMooreEEDrozNMHemodilution is not critical in the pathogenesis of the acute coagulopathy of traumaJ Surg Res20121731263021696767
  • WohlauerMVMooreEEThomasSEarly platelet dysfunction: an unrecognized role in the acute coagulopathy of traumaJ Am Coll Surg2012214573974622520693
  • CastellinoFJChapmanMPDonahueDLTraumatic brain injury causes platelet adenosine diphosphate and arachidonic acid receptor inhibition independent of hemorrhagic shock in humans and ratsJ Trauma Acute Care Surg20147651169117624747445
  • GandoSSawamuraAHayakawaMTrauma, shock, and disseminated intravascular coagulation: lessons from the classical literatureAnn Surg20112541101921368657
  • ParkMSOwenBABallingerBAQuantification of hypercoagulable state after blunt trauma: microparticle and thrombin generation are increased relative to injury severity, while standard markers are notSurgery2012151683183622316436
  • ParkMSXueASpearsGMThrombin generation and procoagulant microparticle profiles after acute trauma: a prospective cohort studyJ Trauma Acute Care Surg201579572673126496097
  • MatijevicNWangYWWadeCECellular microparticle and thrombogram phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study: correlation with coagulopathyThromb Res2014134365265825086657
  • TianYSalsberyBWangMBrain-derived microparticles induce systemic coagulation in a murine model of traumatic brain injuryBlood2015125132151215925628471
  • NekludovMMobarrezFGrythDBellanderBMWallenHFormation of microparticles in the injured brain of patients with severe isolated traumatic brain injuryJ Neurotrauma201431231927193324956150
  • ZhangQRaoofMChenYCirculating mitochondrial DAMPs cause inflammatory responses to injuryNature2010464728510410720203610
  • JohanssonPIWindelovNARasmussenLSSorensenAMOstrowskiSRBlood levels of histone-complexed DNA fragments are associated with coagulopathy, inflammation and endothelial damage early after traumaJ Emerg Trauma Shock20136317117523960372
  • CohenMJBrohiKCalfeeCSEarly release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusionCrit Care2009136R17419887013
  • GiannoudisPVMallinaRHarwoodPPerrySSanteEDPapeHCPattern of release and relationship between HMGB-1 and IL-6 following blunt traumaInjury201041121323132720887988
  • TreutigerCJMullinsGEJohanssonASHigh mobility group 1 B-box mediates activation of human endotheliumJ Intern Med2003254437538512974876
  • LevratAGrosARugeriLEvaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patientsBr J Anaesth2008100679279718440953
  • SchochlHFrietschTPavelkaMJamborCHyperfibrinolysis after major trauma: differential diagnosis of lysis patterns and prognostic value of thrombelastometryJ Trauma200967112513119590321
  • SchochlHVoelckelWMaegeleMSolomonCTrauma-associated hyperfibrinolysisHamostaseologie2012321222722009115
  • LongstaffCKolevKBasic mechanisms and regulation of fibrinolysisJ Thromb Haemost201513Suppl 1S9810526149056
  • CottonBAHarvinJAKostousouvVHyperfibrinolysis at admission is an uncommon but highly lethal event associated with shock and prehospital fluid administrationJ Trauma Acute Care Surg201273236537022846941
  • ChapmanMPMooreEEMooreHBThe “Black Diamond”: Rapid thrombelastography identifies lethal hyperfibrinolysisJ Trauma Acute Care Surg201579692592926488324
  • AllardSGreenLHuntBJHow we manage the haematological aspects of major obstetric haemorrhageBr J Haematol2014164217718824383841
  • JohanssonPStensballeJOstrowskiSShock induced endotheliopathy (SHINE) in acute critical illness - a unifying pathophysiologic mechanismCrit Care20172112528179016
  • WhiteNJWardKRPatiSStrandenesGCapAPHemorrhagic blood failure: oxygen debt, coagulopathy, and endothelial damageJ Trauma Acute Care Surg2017826S Suppl 1S41S4928328671
  • OstrowskiSRJohanssonPIEndothelial glycocalyx degradation induces endogenous heparinization in patients with severe injury and early traumatic coagulopathyJ Trauma Acute Care Surg2012731606622743373
  • JohanssonPIOstrowskiSRAcute coagulopathy of trauma: balancing progressive catecholamine induced endothelial activation and damage by fluid phase anticoagulationMed Hypotheses201075656456720708846
  • HayakawaMGandoSOnoYWadaTYanagidaYSawamuraAFibrinogen level deteriorates before other routine coagulation parameters and massive transfusion in the early phase of severe trauma: a retrospective observational studySemin Thromb Hemost2015411354225590522
  • HayakawaMSawamuraAGandoSDisseminated intravascular coagulation at an early phase of trauma is associated with consumption coagulopathy and excessive fibrinolysis both by plasmin and neutrophil elastaseSurgery2011149222123020655560
  • YanagidaYGandoSSawamuraANormal prothrombinase activity, increased systemic thrombin activity, and lower antithrombin levels in patients with disseminated intravascular coagulation at an early phase of trauma: comparison with acute coagulopathy of trauma-shockSurgery20131541485723684364
  • CardenasJCMatijevicNBaerLAHolcombJBCottonBAWadeCEElevated tissue plasminogen activator and reduced plasminogen activator inhibitor promote hyperfibrinolysis in trauma patientsShock201441651452124667610
  • CardenasJCWadeCEHolcombJBMechanisms of trauma-induced coagulopathyCurr Opin Hematol201421540440925010798
  • ChapmanMPMooreEERamosCRFibrinolysis greater than 3% is the critical value for initiation of antifibrinolytic therapyJ Trauma Acute Care Surg201375696196724256667
  • MooreHBMooreEEHuebnerBRFibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activatorJ Trauma Acute Care Surg20178361014102229190254
  • DavenportRPathogenesis of acute traumatic coagulopathyTransfusion201353Suppl 123S27S23301969
  • RazaIDavenportRRourkeCThe incidence and magnitude of fibrinolytic activation in trauma patientsJ Thromb Haemost201311230731423176206
  • ShakurHRobertsIBautistaREffects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trialLancet20103769734233220554319
  • MooreHBMooreEEGonzalezEHyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown: the spectrum of postinjury fibrinolysis and relevance to antifibrinolytic therapyJ Trauma Acute Care Surg201477681181725051384
  • AlamAQUse of TXA to Prevent Postpartum Hemorrhage (TAPPH-1) Available from: https://clinicaltrials.gov/ct2/show/NCT03069859?term=NCT03069859&rank=1Accessed May 18, 2018
  • ShakurHHaemorrhage Alleviation With Tranexamic Acid-Intestinal System (HALT-IT) NCT016581242018 Available from: https://clinicaltrials.gov/ct2/show/NCT01658124?term=HALT-IT&rank=1Accessed May 5, 2018
  • PanteliMPountosIGiannoudisPVPharmacological adjuncts to stop bleeding: options and effectivenessEur J Trauma Emerg Surg201642330331026660675
  • RourkeCCurryNKhanSFibrinogen levels during trauma hemorrhage, response to replacement therapy, and association with patient outcomesJ Thromb Haemost20121071342135122519961
  • BesserMWMacDonaldSGAcquired hypofibrinogenemia: current perspectivesJ Blood Med2016721722527713652
  • HagemoJSStanworthSJuffermansNPPrevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational studyCrit Care2014182R5224666991
  • vanDeWaterLCarrJMAronsonDMcDonaghJAnalysis of elevated fibrin(ogen) degradation product levels in patients with liver diseaseBlood1986675146814732938648
  • MartiniJMaischSPilshoferLStreifWMartiniWFriesDFibrinogen concentrate in dilutional coagulopathy: a dose study in pigsTransfusion201454114915723672536
  • MartiniWZCoagulopathy by hypothermia and acidosis: mechanisms of thrombin generation and fibrinogen availabilityJ Trauma200967120220819590336
  • HuntBJSegalHHyperfibrinolysisJ Clin Pathol199649129589038728
  • StachurskaJLatalloZKopecMInhibition of platelet aggregation by dialysable fibrinogen degradation products (FDP)Thromb Diath Haemorrh197023191985420436
  • LevyJHGreenbergCBiology of Factor XIII and clinical manifestations of Factor XIII deficiencyTransfusion20135351120113122928875
  • AndreasonCLPohlmanTHDamage control resuscitation for catastrophic bleedingOral Maxillofac Surg Clin North Am201628455356827745621
  • PapadopoulosDSiempisTTheodorakouETsoulfasGHepatic ischemia and reperfusion injury and trauma: current conceptsArch Trauma Res201322637024396796
  • SatterlySAMartinMWingerdMHempelJHofferZStallingsJDFlutamide fails to reduce resuscitation requirements in a porcine ischemia-reperfusion modelJ Surg Res2013184147247923791438
  • SingerMCritical illness and flat batteriesCrit Care201721Suppl 330929297363
  • WaxmanKShock: ischemia, reperfusion, and inflammationNew Horiz1996421531608774791
  • JorchSKKubesPAn emerging role for neutrophil extracellular traps in noninfectious diseaseNat Med201723327928728267716
  • RaymondSLHoldenDCMiraJCMicrobial recognition and danger signals in sepsis and traumaBiochim Biophys Acta2017186310 Pt B2564257328115287
  • WagnerNDieterenSFranzNEthyl pyruvate ameliorates hepatic injury following blunt chest trauma and hemorrhagic shock by reducing local inflammation, NF-kappaB activation and HMGB1 releasePLoS One2018132e019217129420582
  • EppensteinerJDavisRPBarbasASKwunJLeeJImmunothrombotic activity of damage-associated molecular patterns and extracellular vesicles in secondary organ failure induced by trauma and sterile insultsFront Immunol2018919029472928
  • LevyRMMollenKPPrinceJMSystemic inflammation and remote organ injury following trauma require HMGB1Am J Physiol Regul Integr Comp Physiol20072934R1538R154417652366
  • EskiciZMAcikgozSPiskinNHigh mobility group B1 levels in sepsis and disseminated intravascular coagulationActa Biochim Pol201259456156623094260
  • HatadaTWadaHNoboriTPlasma concentrations and importance of high mobility group box protein in the prognosis of organ failure in patients with disseminated intravascular coagulationThromb Haemost200594597597916363239
  • GandoSMicrovascular thrombosis and multiple organ dysfunction syndromeCrit Care Med2010382 SupplS35S4220083912
  • ItoTKawaharaKNakamuraTHigh-mobility group box 1 protein promotes development of microvascular thrombosis in ratsJ Thromb Haemost20075110911617239166
  • ZettelKRDyerMRavalJSAged human stored red blood cell supernatant inhibits macrophage phagocytosis in an HMGB1 dependent manner after trauma in a murine modelShock201747221722427488090
  • ThurairajahKBriggsGDBaloghZJThe source of cell-free mitochondrial DNA in trauma and potential therapeutic strategiesEur J Trauma Emerg Surg Epub201849
  • NakahiraKKyungSYRogersAJCirculating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validationPLoS Med20131012e100157724391478
  • BlackGESokolKKMoeDMImpact of a novel phosphoinositol-3 kinase inhibitor in preventing mitochondrial DNA damage and damage-associated molecular pattern accumulation: results from the Biochronicity ProjectJ Trauma Acute Care Surg201783468368928930961
  • McNabABurnsBBhullarIChesireDKerwinAA prehospital shock index for trauma correlates with measures of hospital resource use and mortalitySurgery2012152347347622938906
  • MitraBFitzgeraldMChanJThe utility of a shock index ≥1 as an indication for pre-hospital oxygen carrier administration in major traumaInjury2014451616523391451
  • MutschlerMNienaberUMunzbergMThe Shock Index revisited - a fast guide to transfusion requirement? A retrospective analysis on 21,853 patients derived from the TraumaRegister DGU(R)Crit Care2013174R17223938104
  • CamazineMNHemmilaMRLeonardJCMassive transfusion policies at trauma centers participating in the American College of Surgeons Trauma Quality Improvement ProgramJ Trauma Acute Care Surg2015786 Suppl 1S485326002263
  • TongletMLEarly Prediction of Ongoing Hemorrhage in Severe Trauma: Presentation of the Existing Scoring SystemsArch Trauma Res201654e3337728144603
  • ArakakiLSLBulgerEMCiesielskiWAMuscle oxygenation as an early predictor of shock severity in trauma patientsShock201747559960527820776
  • SchenkmanKACarlbomDJBulgerEMMuscle oxygenation as an indicator of shock severity in patients with suspected severe sepsis or septic shockPLoS One2017128e018235128771567
  • SchenkmanKAHawkinsDSCiesielskiWADelaneyMArakakiLSNon-invasive assessment of muscle oxygenation may aid in optimising transfusion threshold decisions in ambulatory paediatric patientsTransfus Med2017271252928070916
  • ArakakiLSSchenkmanKACiesielskiWAShaverJMMuscle oxygenation measurement in humans by noninvasive optical spectroscopy and locally weighted regressionAnal Chim Acta2013785273323764440
  • HolcombJBTilleyBCBaraniukSTransfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trialJAMA2015313547148225647203
  • FahrendorffMOliveriRSJohanssonPIThe use of viscoelastic haemostatic assays in goal-directing treatment with allogeneic blood products – a systematic review and meta-analysisScand J Trauma Resusc Emerg Med20172513928403868
  • LopezESrivastavaAKPatiSHolcombJBWadeCEPlatelet-derived microvesicles: a potential therapy for trauma-induced coagulopathyShock201849324324828858139
  • HickmanDAPawlowskiCLSekhonUDSMarksJGuptaASBiomaterials and advanced technologies for hemostatic management of bleedingAdv Mater20183041700859
  • Centers for Disease C, PreventionFatal bacterial infections associated with platelet transfusions -- United States, 2004MMWR Morb Mortal Wkly Rep200554716817015729217
  • EstcourtLJMaloufRHopewellSPathogen-reduced platelets for the prevention of bleedingCochrane Database Syst Rev20177CD00907228756627
  • VamvakasECRelative safety of pooled whole blood-derived versus single-donor (apheresis) platelets in the United States: a systematic review of disparate risksTransfusion200949122743275819682339
  • AckerJPMarksDCSheffieldWPQuality assessment of established and emerging blood components for transfusionJ Blood Transfus20162016486028428070448
  • Neisser-SvaeATrawnicekLHegerAMehtaTTriulziDFive-day stability of thawed plasma: solvent/detergent-treated plasma comparable with fresh-frozen plasma and plasma frozen within 24 hoursTransfusion201656240440926419404
  • HessJRHolcombJBResuscitating PROPPRlyTransfusion20155561362136425858048
  • MayrWRHaemovigilance: are there significant differences among plasma products?Transfus Apher Sci201043340740920934384
  • PitkanenHJouppilaAMowinckelMCEnhanced thrombin generation and reduced intact protein S in processed solvent detergent plasmaThromb Res2015135116717425466844
  • HegerANeisser-SvaeATrawnicekLTriulziDThrombin generation potential and clot-forming capacity of thawed fresh-frozen plasma, plasma frozen within 24 h and solvent/detergent-treated plasma (octaplasLG((R))), during 5-day storage at 1–6 degrees CVox Sang Epub2018423
  • USFDA2018 Available from: https://www.fda.gov/downloads/biologicsbloodvaccines/bloodbloodproducts/approvedproducts/licensedproductsblas/ucm336161.pdfAccessed May 18, 2018
  • ChhibberVGreeneMVauthrinMBaileyJWeinsteinRIs group A thawed plasma suitable as the first option for emergency release transfusion? (CME)Transfusion20145471751175524400951
  • CoolingLGoing from A to B: the safety of incompatible group A plasma for emergency release in trauma and massive transfusion patientsTransfusion20145471695169725041147
  • MehrCRGuptaRvon RecklinghausenFMSzczepiorkowskiZMDunbarNMBalancing risk and benefit: maintenance of a thawed Group A plasma inventory for trauma patients requiring massive transfusionJ Trauma Acute Care Surg20137461425143123694868
  • WinearlsJCampbellDHurnCFibrinogen in traumatic haemorrhage: a narrative reviewInjury201748223024228088374
  • WinearlsJWullschlegerMWakeEFibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trialTrials201718124128549445
  • OkerbergCKWilliamsLA3rdKilgoreMLCryoprecipitate AHF vs. fibrinogen concentrates for fibrinogen replacement in acquired bleeding patients - an economic evaluationVox Sang2016111329229827248502
  • KriebardisAGAntonelouMHGeorgatzakouHTTzounakasVLStamoulisKEPapassideriISMicroparticles variability in fresh frozen plasma: preparation protocol and storage time effectsBlood Transfus201614222823727136430
  • FrancisCWMarderVJIncreased resistance to plasmic degradation of fibrin with highly crosslinked alpha-polymer chains formed at high factor XIII concentrationsBlood1988715136113652965927
  • GerlachRTolleFRaabeAZimmermannMSiegemundASeifertVIncreased risk for postoperative hemorrhage after intracranial surgery in patients with decreased factor XIII activity: implications of a prospective studyStroke20023361618162312053001
  • KarkoutiKvon HeymannCJespersenCMEfficacy and safety of recombinant factor XIII on reducing blood transfusions in cardiac surgery: a randomized, placebo-controlled, multicenter clinical trialJ Thorac Cardiovasc Surg2013146492793923820174
  • NascimentoBGoodnoughLTLevyJHCryoprecipitate therapyBr J Anaesth2014113692293424972790
  • KeyNSNegrierCCoagulation factor concentrates: past, present, and futureLancet2007370958543944817679021
  • HauserCJBoffardKDuttonRResults of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhageJ Trauma201069348950020838118
  • MurthiSBStansburyLGDuttonRPEdelmanBBScaleaTMHessJRTransfusion medicine in trauma patients: an updateExpert Rev Hematol20114552753721939420
  • KrautJAMadiasNESerum anion gap: its uses and limitations in clinical medicineClin J Am Soc Nephrol20072116217417699401
  • McCarronDAElliottWCRoseJSBennettWMSevere mixed metabolic acidosis secondary to rhabdomyolysisAm J Med1979675905908507101
  • KrautJAMadiasNEMetabolic acidosis: pathophysiology, diagnosis and managementNat Rev Nephrol20106527428520308999
  • WolbergASMengZHMonroeDM3rdHoffmanMA systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet functionJ Trauma20045661221122815211129
  • KermodeJCZhengQMilnerEPMarked temperature dependence of the platelet calcium signal induced by human von Willebrand factorBlood199994119920710381514
  • KramerLBauerEJoukhadarCCitrate pharmacokinetics and metabolism in cirrhotic and noncirrhotic critically ill patientsCrit Care Med200331102450245514530750
  • KornblithLZKutcherMERedickBJCalfeeCSVilardiRFCohenMJFibrinogen and platelet contributions to clot formation: implications for trauma resuscitation and thromboprophylaxisJ Trauma Acute Care Surg201476225526324458031
  • AsehnouneKBaloghZCiterioGThe research agenda for trauma critical careIntensive Care Med20174391340135128756471
  • ShuklaMSekhonUDBetapudiVIn vitro characterization of SynthoPlate (synthetic platelet) technology and its in vivo evaluation in severely thrombocytopenic miceJ Thromb Haemost201715237538727925685
  • HarrJNMooreEEGhasabyanAFunctional fibrinogen assay indicates that fibrinogen is critical in correcting abnormal clot strength following traumaShock2013391454923247121
  • JegerVWilliSLiuTThe Rapid TEG a-Angle may be a sensitive predictor of transfusion in moderately injured blunt trauma patientsScientific World Journal2012201282179422547997
  • JegerVZimmermannHExadaktylosAKCan RapidTEG accelerate the search for coagulopathies in the patient with multiple injuries?J Trauma20096641253125719359945
  • SchlimpCJSolomonCRanucciMHochleitnerGRedlHSchochlHThe effectiveness of different functional fibrinogen polymerization assays in eliminating platelet contribution to clot strength in thromboelastometryAnesth Analg2014118226927624445628
  • KashukJLMooreEESawyerMPostinjury coagulopathy management: goal directed resuscitation via POC thrombelastographyAnn Surg2010251460461420224372
  • KashukJLMooreEEWohlauerMInitial experiences with point-of-care rapid thrombelastography for management of life-threatening postinjury coagulopathyTransfusion2012521233321790635
  • PommereningMJGoodmanMDFarleyDLEarly diagnosis of clinically significant hyperfibrinolysis using thrombelastography velocity curvesJ Am Coll Surg201421961157116625458237
  • SheenJHHeegerPSEffects of complement activation on allograft injuryCurr Opin Organ Transplant201520446847526132735
  • DavisAE3rdMejiaPLuFBiological activities of C1 inhibitorMol Immunol200845164057406318674818