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Original Research

Serum homocysteine and disease severity in sickle cell anemia patients in Lagos

, , , , , , , , & show all
Pages 127-134 | Published online: 08 May 2019

References

  • Akinyanju OO. Profile of sickle cell disease in Nigeria. Ann NY Acad Sci. 1989;565:126–136.2672962
  • Modell B, Darlison M. Global epidemiology of haemoglobin disorders and derived service indicators. Bull World Health Organ. 2008;86:480–487.18568278
  • Rees D, Williams T, Gladwin M. Sickle-cell disease. Lancet. 2010;376:2018–2031. doi:10.1016/S0140-6736(10)61029-X21131035
  • Serjeant GR. Sickle-cell disease. Lancet. 1997;350:725–730.9291916
  • Taylor TD, Noguchi H, Totoki Y, et al. Human chromosome 11 DNA sequence and analysis including novel gene identification. Nature. 2006;440:491–500. doi:10.1038/nature0461416554810
  • Rahimi Z, Parsian A. Sickle cell disease and venous thromboembolism. Mediterr J Hematol Infect Dis. 2011;3:1–7. doi:10.4084/mjhid.2011.024
  • Steinberg MH. Sickle cell anaemia, the first molecular disease: overview of molecular etiology, pathophysiology, and therapeutic approaches. ScientificWorld J. 2008;8:1295–1324. doi:10.1100/tsw.2008.157
  • Hebbel R, Robert P. Ischemia-reperfusion injury in sickle cell anaemia: relationship to acute chest syndrome, endothelial dysfunction, arterial vasculopathy, and inflammatory pain. Hematol Oncol Clin North Am. 2014;28:181–198. doi:10.1016/j.hoc.2013.11.00524589261
  • Colombatti R, De Bon E, Bertomoro A, et al. Coagulation activation in children with sickle cell disease is associated with cerebral small vessel vasculopathy. PLoS One. 2013;8:311–318.
  • El-Hazmi MA, Warsy AS, Bahakim H. Blood proteins C and S in sickle cell disease. Acta Haematol. 1993;90:114–119. doi:10.1159/0002043908291368
  • Liesner R, Mackie I, Cookson J, et al. Prothrombotic changes in children with sickle cell disease: relationships to cerebrovascular disease and transfusion. Br J Haematol. 1998;103:1037–1044. doi:10.1046/j.1365-2141.1998.01121.x9886316
  • Ataga KI. Hypercoagulability and thrombotic complications in hemolytic anaemias. Haematologica. 2009;94:1481–1484. doi:10.3324/haematol.2009.01367219880774
  • Ataga KI, Cappellini MD, Rachmilewitz EA. β-thalassemia and sickle-cell anaemia as paradigms of hypercoagulability. Br J Haematol. 2007;139:3–13. doi:10.1111/j.1365-2141.2007.06740.x17854302
  • Sati‘Abbas S, Abul–Razak N, Mustafa N, Abd Ali R. Homocysteine, folic acid, vitamin B12 and pyridoxine: effects on vaso-occlusive crisis in sickle cell anemia and sickle –thalassemia. Ipmj. 2011;10:473–479.
  • Chao-Hung HO The influence of age, sex, vitamin B12, folate levels and methylenetetrahydrofolate reductase C677T genetic mutations on plasma homocysteine in the Chinese population. Haematologica. 2000;85:1051–1054.11025596
  • Klee GG. Cobalamin and folate evaluation; measurement of methylmalonic acid and homocysteine vs vitamin B12 and folate. Clin Chem. 2000;46:1277–1283.10926922
  • Toole JF, Malinow MR, Chambless LE, et al. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA. 2004;291:565–575. doi:10.1001/jama.291.5.56514762035
  • Homocysteine Studies collaboration. Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA. 2002;288:2015–2022.12387654
  • Ventura P, Panini R, Tremosini S, Salvioli G. A role for homocysteine increase in haemolysis of megaloblastic anaemias due to vitamin B(12) and folate deficiency: results from an in vitro experience. Biochim Biophys Acta. 2004;1739:33–42. doi:10.1016/j.bbadis.2004.08.00515607115
  • Mansoor MA, Bergmark C, Svardal AM, Lonning PE, Ueland PM. Redox status and protein binding of plasma homocysteine and other aminothiols in patients with early-onset peripheral vascular disease. Homocysteine and peripheral vascular disease. Arterioscler Thromb Vasc Biol. 1995;15:232.7749831
  • Al-Obaidi MK, Philippou H, Stubbs PJ, et al. Relationships between homocysteine, factor VIIa, and thrombin generation in acute coronary syndromes. Circulation. 2000;101:372.10653827
  • Nappo F, De Rossa N, Marfella R, et al. Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins. JAMA. 1999;281:2113. doi:10.1001/jama.281.22.211310367822
  • Hajjar KA. Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor. J Clin Invest. 1993;91:2873. doi:10.1172/JCI1165328390492
  • Stamler JS, Osborne JA, Jaraki O, et al. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. J Clin Invest. 1993;91:308.8380812
  • McCully KS. Homocysteine and vascular disease. Nat Med. 1996;2:386. doi:10.1038/nm0496-3868597939
  • Houston PE, Rana S, Sekhsaria S, Perlin E, Kim KS, Castro OL. Homocysteine in sickle cell: relationship to stroke. Am J Med. 1997;103:192–196.9316551
  • Van der Dijis FLP, Schong J, Brouwer DAJ, et al. Elevated homocysteine levels indicate suboptimal folate status in paediatric sickle cell patients. Am J Hematol. 1998;59:192–198.9798656
  • Prengler M, Pavlakis SG, Prohovik I, Adams RJ. Sickle cell disease: the neurological complications. Ann Neurol. 2002;51:543–552. doi:10.1002/ana.1019212112099
  • Al-Maktari L, Al-Nuzaily M, Bamashmoos S, Taresh S, Ali F. Thrombotic events in pateints with sickle cell anaemia: relationship to protein C, S and total homocysteine levels. Int J Curr Res Aca Rev. 2014;2:17–24.
  • Pandey S, Pandey HR, Mishra RM, Pandey S, Saxena R. Increased homocysteine level in Indian sickle cell patients. Ind J Clin Biochem. 2012;27:103–104.
  • Driss A, Asare KO, Hibbert JM, Gee BE, Adamkiewicz TV, Stiles JK. Sickle cell disease in the post genomic era: a monogenic disease with a polygenic phenotype. Genomic Insights. 2009;2:23–48. doi:10.4137/GEI.S2626
  • Van Den Tweel XW. Measurement of disease severity in patients with sickle cell disease: a systematic review [PhD Thesis] 2009; 42–52.
  • Steinberg MH, Dreiling BJ, Morrison FS, Necheles TF. Mild sickle cell disease. Clinical and Laboratory studies. JAMA. 1973;224:317–321.4739533
  • Odenheimer DJ, Sarnaik SA, Whitten CF, Rucknagel DL, Sing CF. The relationship between fetal hemoglobin and disease severity in children with sickle cell anaemia. Am J Med Genet. 1987;27:525–535. doi:10.1002/ajmg.13202703052443006
  • Bray GL, Muenz L, Makris N, Lessin LS. Assessing clinical severity in children with sickle cell disease. Preliminary results from a cooperative study. Am J Pediatr Hematol Oncol. 1994;16:50–54.8311173
  • Miller ST, Sleeper LA, Pegelow CH, et al. Prediction of adverse outcomes in children with sickle cell disease. N Engl J Med. 2000;342:83–89. doi:10.1056/NEJM20000113342020310631276
  • Steinberg MH. Predicting clinical severity in sickle cell anaemia. Br J Haematol. 2005;129:465–481. doi:10.1111/j.1365-2141.2005.05411.x15877729
  • Sebastiani P, Nolan VG, Baldwin CT, et al. A network model to predict the risk of death in sickle cell disease. Blood. 2007;110:2727–2735. doi:10.1182/blood-2007-04-08492117600133
  • Adegoke SA, Kuti BP. Evaluation of clinical severity of sickle cell anaemia in Nigerian children. J Appl Haematol. 2013;4:58–64.
  • Hedo CC, Okpala IE, Aken‘Ova YA. Foetal haemoglobin levels in Nigerians with sickle cell anaemia. A revisitation. Trop Geogr Med. 1993;45:162–164.7694410
  • Akinola NO, Stevens SM, Franklin IM, Nash GB, Stuart J. Subclinical ischaemic episodes during the steady state of sickle cell anaemia. J Clin Pathol. 1992;45:902–906.1385483
  • Hedo CC, Aken'ova YA, Okpala IE, Durojaiye AO, Salimonu LS. Acute phase reactants and severity of homozygous sickle cell disease. J InternMed. 1993;233:467–470.
  • Akinlade KS, Atere AD, Rahamon SK, Olaniyi JA. Serum levels of copeptin, C-reactive protein and cortisol in different severity groups of sickle cell anaemia. Niger J Physiol Sci. 2013;28:159–164.24937391
  • Dhar M, Bellevue R, Brar S, Carmel R. Mild hyperhomocysteinemia in adult patients with sickle cell disease: a common finding unrelated to folate and cobalamin status. Am J Hemat. 2004;76:114–120. doi:10.1002/ajh.2007315164375
  • Lowenthal EA, Mayo MS, Cornwell PE, Thornley-Brown D. Homocysteine elevation in sickle cell disease. J Am Coll Nutri. 2000;24:374–379.
  • Olaniyi J, Akinlade K, Atere A, Arinola O. Plasma homocysteine, methyl-malonic acid, vitamin B12 and folate levels in adult Nigerian sickle cell anaemia patients. Br J Med Med Res. 2014;4:1327–1334. doi:10.9734/BJMMR/2014/3989
  • Rodriguez-Cortes HM, Griener JC, Hyland K, et al. Plasma Homocysteine levels. J Pediatri Hemat/Onco. 1999;21(3):173–174.
  • Friedman AN, Boston AG, Selhub J, Levey AS, Rosenberg IH, Kidney T. Homocysteine metabolism. J Am Soc Neph. 2001;12(1):2181–2189.
  • Al-Saqladi AM, Delpisheh A, Bin-Gadeem HA, Brabin BJ. Severity of sickle cell disease in Yemeni children. J Trop Pediat. 2009;55:208–209. doi:10.1093/tropej/fmn109
  • Diagne I, Ndiaye O, Moreira C, et al. Sickle cell disease in children in Dakar, Senegal. Arch Pediatr. 2000;7(1):16–24.10668081
  • El-Hazmi MA. Clinical and haematological diversity of sickle cell disease in Saudi children. J Trop Pediatr. 1992;38:106–112. doi:10.1093/tropej/38.3.1061380566
  • Rugani MA. Association of Homocysteine with Vaso-Occlusive Crisis in Sickle Cell Disease. Brazil:Fluminense Federal university;2008 Available from: http://www.bdtd.ndc.uff.br/tde_arquivos/33/TDE-2009-06-17T090656Z-2093/Publico/TEDE-Dissert-Marilia%20Rugani.pdf.
  • Bradley AM, Joseph L. The treatment of hyperhomocysteinemia. Annu Rev Med. 2009;60:39–54. doi:10.1146/annurev.med.60.041807.12330818729731