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Original Research

Effects of Iron Deficiency and Its Indicators on Lymphocyte Subsets: A Study at King Fahd Hospital of the University, Saudi Arabia

ORCID Icon, ORCID Icon, ORCID Icon, &
Pages 61-67 | Published online: 16 Feb 2022

References

  • Chandra RK. Nutrition and the immune system from birth to old age. Eur J Clin Nutr. 2002;56(Suppl 3):S73–S76. doi:10.1038/sj.ejcn.1601492
  • Hall A, Bobrow E, Brooker S, et al. Anaemia in schoolchildren in eight countries in Africa and Asia. Public Health Nutr. 2001;4(3):749–756. doi:10.1079/PHN2000111
  • Collins HL, Kaufmann SH, Schaible UE. Iron chelation via deferoxamine exacerbates experimental salmonellosis via inhibition of the nicotinamide adenine dinucleotide phosphate oxidase-dependent respiratory burst. J Immunol. 2002;168(7):3458–3463. doi:10.4049/jimmunol.168.7.3458
  • Omara FO, Blakley BR. The effects of iron deficiency and iron overload on cell-mediated immunity in the mouse. Br J Nutr. 1994;72(6):899–909. doi:10.1079/BJN19940094
  • Sejas E, Kolsteren P, Hoeree T, Roberfroid D. Iron supplementation in previously anemic Bolivian children normalized hematologic parameters, but not immunologic parameters. J Trop Pediatr. 2008;54(3):164–168. doi:10.1093/tropej/fmm106
  • Ekiz C, Agaoglu L, Karakas Z, Gurel N, Yalcin I. The effect of iron deficiency anemia on the function of the immune system. Haematol J. 2005;5(7):579–583. doi:10.1038/sj.thj.6200574
  • Tang YM, Chen XZ, Li GR, Zhou RH, Ning H, Yan H. [Effects of iron deficiency anemia on immunity and infectious disease in pregnant women]. Wei Sheng Yan Jiu. 2006;35(1):79–81. Chinese.
  • Schaible UE, Kaufmann SH. Iron and microbial infection. Nat Rev Microbiol. 2004;2(12):946. doi:10.1038/nrmicro1046
  • Mast AE, Blinder MA, Gronowski AM, Chumley C, Scott MG. Clinical utility of the soluble transferrin receptor and comparison with serum ferritin in several populations. Clin Chem. 1998;44(1):45–51. doi:10.1093/clinchem/44.1.45
  • Soppi ET. Iron deficiency without anemia - a clinical challenge. Clin Case Rep. 2018;6(6):1082–1086. doi:10.1002/ccr3.1529
  • Bhaskaram P. Micronutrient malnutrition, infection, and immunity: an overview. Nutr Rev. 2002;60(5 Pt 2):S40–S45. doi:10.1301/00296640260130722
  • Vydyborets SV. [An analysis of the immunity indices of patients with iron-deficiency anemia]. Lik Sprava. 2000;3–4:71–75. Ukrainian.
  • Soyano A, Gomez M. [Role of iron in immunity and its relation with infections]. Arch Latinoam Nutr. 1999;49(3Suppl 2):40S–6S. Spanish.
  • Aly SS, Fayed HM, Ismail AM, Abdel Hakeem GL. Assessment of peripheral blood lymphocyte subsets in children with iron deficiency anemia. BMC Pediatr. 2018;18(1):49. doi:10.1186/s12887-018-0990-5
  • Özcan A, Çakmak M, Toraman AR, et al. Evaluation of leucocyte and its subgroups in iron deficiency anemia. Int J Med Med Sci. 2011;3(5):135–138.
  • Mullick S, Rusia U, Sikka M, Faridi MA. Impact of iron deficiency anaemia on T lymphocytes & their subsets in children. Indian J Med Res. 2006;124(6):647–654.
  • Santos PC, Falcao RP. Decreased lymphocyte subsets and K-cell activity in iron deficiency anemia. Acta Haematol. 1990;84(3):118–121. doi:10.1159/000205047
  • Berger J, Schneider D, Dyck J-L, et al. Iron deficiency, cell-mediated immunity and infection among 6–36 month old children living in rural Togo. Nutr Res. 1992;12(1):39–49. doi:10.1016/S0271-5317(05)80408-7
  • Attia MA, Essa SA, Nosair NA, Amin AM, El-Agamy OA. Effect of iron deficiency anemia and its treatment on cell mediated immunity. Indian J Hematol Blood Transfus. 2009;25(2):70–77. doi:10.1007/s12288-009-0017-3
  • van Heerden R. Evaluation of neutrophil and lymphocyte function in subjects with iron deficiency. S Afr Med J. 1981;59(4):111–113.
  • Sherman AR, Lockwood JF. Impaired natural killer cell activity in iron-deficient rat pups. J Nutr. 1987;117(3):567–571. doi:10.1093/jn/117.3.567
  • Spear AT, Sherman AR. Iron deficiency alters DMBA-induced tumor burden and natural killer cell cytotoxicity in rats. J Nutr. 1992;122(1):46–55. doi:10.1093/jn/122.1.46
  • Bami MH, Mohri M, Seifi HA, Tabatabaee AA. Effects of parenteral supply of iron and copper on hematology, weight gain, and health in neonatal dairy calves. Vet Res Commun. 2008;32(7):553–561. doi:10.1007/s11259-008-9058-6
  • Thibault H, Galan P, Selz F, et al. The immune response in iron-deficient young children: effect of iron supplementation on cell-mediated immunity. Eur J Pediatr. 1993;152(2):120–124. doi:10.1007/BF02072487
  • Beard JL. Iron biology in immune function, muscle metabolism and neuronal functioning. J Nutr. 2001;131(2s–2):568S–79S; discussion 80S. doi:10.1093/jn/131.2.568S