189
Views
0
CrossRef citations to date
0
Altmetric
Original Research

Peripheral Cytopenia and Its Associated Factors in Type 2 Diabetes Mellitus Patients, Northwest Ethiopia

ORCID Icon, ORCID Icon & ORCID Icon
Pages 373-383 | Published online: 04 Jul 2022

References

  • Milosevic D, Panin VL. Relationship between hematological parameters and glycemic control in type 2 diabetes mellitus patients. J Med Biochem. 2019;38(2):164. doi:10.2478/jomb-2018-0021
  • Panda AK, Ambade RA. Prevalence of anemia and its correlation with HBA1c of patients in type-II diabetes mellitus: a pilot study. National J Physiol Pharm Pharmacol. 2018;8(10):1409–1413. doi:10.5455/njppp.2018.8.0621511072018
  • Antwi-Baffour S, Kyeremeh R, Boateng SO, Annison L, Seidu MA. Haematological parameters and lipid profile abnormalities among patients with Type-2 diabetes mellitus in Ghana. Lipids Health Dis. 2018;17(1):1–9. doi:10.1186/s12944-018-0926-y
  • Jain A, Naniwadekar M. An etiological reappraisal of pancytopenia-largest series reported to date from a single tertiary care teaching hospital. BMC Blood Disord. 2013;13(1):1–9. doi:10.1186/2052-1839-13-10
  • Atlaw D, Tariku Z. Magnitude and factors associated with anemia among diabetic patients in Ethiopia: a systematic review and meta-analysis. SAGE Open Med. 2021;9:20503121211031126. doi:10.1177/20503121211031126
  • Thomas MC, MacIsaac RJ, Tsalamandris C, Power D, Jerums G. Unrecognized anemia in patients with diabetes: a cross-sectional survey. Diabetes Care. 2003;26(4):1164–1169. doi:10.2337/diacare.26.4.1164
  • Greenburg AG. Pathophysiology of anemia. Am J Med. 1996;101(2):7S–11S. doi:10.1016/S0002-9343(96)00161-1
  • Al-Salman M. Anemia in patients with diabetes mellitus: prevalence and progression. General Med. 2015;1:1–4.
  • Barbieri J, Fontela PC, Winkelmann ER, et al. Anemia in patients with type 2 diabetes mellitus. Anemia. 2015;2015:548.
  • Alamri B, Bahabri A, Aldereihim A, et al. Hyperglycemia effect on red blood cells indices. Eur Rev Med Pharmacol Sci. 2019;23(5):2139–2150. doi:10.26355/eurrev_201903_17259
  • Digman C, Klein AK, Pittas AG. Leukopenia and thrombocytopenia caused by thiazolidinediones. Ann Intern Med. 2005;143(6):465–466. doi:10.7326/0003-4819-143-6-200509200-00016
  • Shimizu H. Thrombocytopenia in insulin-dependent diabetes mellitus. KITAKANTO Med J. 1998;48(4):283–285. doi:10.2974/kmj.48.283
  • Vinik AI, Erbas T, Park TS, Nolan R, Pittenger GL. Platelet dysfunction in type 2 diabetes. Diabetes Care. 2001;24(8):1476–1485. doi:10.2337/diacare.24.8.1476
  • Park J-M, Lee HS, Park J-Y, Jung D-H, Lee J-W. White blood cell count as a predictor of incident type 2 diabetes mellitus among non-obese adults: a longitudinal 10-year analysis of the Korean genome and epidemiology study. J Inflamm Res. 2021;14:1235. doi:10.2147/JIR.S300026
  • Moradi S, Kerman SRJ, Rohani F, Salari F. Association between diabetes complications and leukocyte counts in Iranian patients. J Inflamm Res. 2012;5:7. doi:10.2147/JIR.S26917
  • Biadgo B, Melku M, Abebe SM, Abebe M. Hematological indices and their correlation with fasting blood glucose level and anthropometric measurements in type 2 diabetes mellitus patients in Gondar, Northwest Ethiopia. Diabetes Metab Syndrome Obesity. 2016;9:91. doi:10.2147/DMSO.S97563
  • Naseem S, Varma N, Das R, Ahluwalia J, Sachdeva MUS, Marwaha RK. Pediatric patients with bicytopenia/pancytopenia: review of etiologies and clinico-hematological profile at a tertiary center. Indian J Pathol Microbiol. 2011;54(1):75. doi:10.4103/0377-4929.77329
  • Yang X, Yu Y, Xu J, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020;8(5):475–481. doi:10.1016/S2213-2600(20)30079-5
  • Hales CM, Fryar CD, Carroll MD, Freedman DS, Ogden CL. Trends in Obesity and Severe Obesity Prevalence in US Youth and Adults by Sex and Age, 2007-2008 to 201-2016. JAMA. 2018;319(16):1723–1725. doi:10.1001/jama.2018.3060
  • Collins SE, Kirouac M. Alcohol Consumption. In: Gellman MD, Turner JR, editors. Encyclopedia of Behavioral Medicine. New York: Springer New York; 2013:61–65.
  • Association AD. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2004;27(suppl_1):s5–s10.
  • Craig KJ, Williams JD, Riley SG, et al. Anemia and diabetes in the absence of nephropathy. Diabetes Care. 2005;28(5):1118–1123. doi:10.2337/diacare.28.5.1118
  • Thomas MC, MacIsaac RJ, Tsalamandris C, et al. The burden of anaemia in type 2 diabetes and the role of nephropathy: a cross-sectional audit. Nephrol Dialysis Transplantation. 2004;19(7):1792–1797. doi:10.1093/ndt/gfh248
  • Al-Khoury S, Afzali B, Shah N, Covic A, Thomas S, Goldsmith D. Anaemia in diabetic patients with chronic kidney disease—prevalence and predictors. Diabetologia. 2006;49(6):1183–1189. doi:10.1007/s00125-006-0254-z
  • Kebede SA, Tusa BS, Weldesenbet AB. Prevalence of anaemia and its associated factors among type 2 diabetes mellitus patients in University of Gondar comprehensive specialized hospital. Anemia. 2021;2021:154.
  • Taderegew MM, Gebremariam T, Tareke AA, Woldeamanuel GG. Anemia and its associated factors among type 2 diabetes mellitus patients attending Debre Berhan Referral Hospital, North-East Ethiopia: a cross-sectional study. J Blood Med. 2020;11:47. doi:10.2147/JBM.S243234
  • Engidaw MT, Feyisa MS. Prevalence of anemia and its associated factors among adult diabetes mellitus patients at Debre Tabor General Hospital, Northcentral Ethiopia. Diabetes Metab Syndrome Obesity. 2020;13:5017. doi:10.2147/DMSO.S286365
  • Adane T, Getawa S. Anaemia and its associated factors among diabetes mellitus patients in Ethiopia: a systematic review and meta‐analysis. Endocrinol Diabetes Metab. 2021;4(3):e00260. doi:10.1002/edm2.260
  • Mbanya JCN, Motala AA, Sobngwi E, Assah FK, Enoru ST. Diabetes in sub-saharan Africa. lancet. 2010;375(9733):2254–2266. doi:10.1016/S0140-6736(10)60550-8
  • Tong PC, Kong AP, So W-Y, et al. Hematocrit, independent of chronic kidney disease, predicts adverse cardiovascular outcomes in Chinese patients with type 2 diabetes. Diabetes Care. 2006;29(11):2439–2444. doi:10.2337/dc06-0887
  • Zoppini G, Targher G, Chonchol M, et al. Anaemia, independent of chronic kidney disease, predicts all-cause and cardiovascular mortality in type 2 diabetic patients. Atherosclerosis. 2010;210(2):575–580. doi:10.1016/j.atherosclerosis.2009.12.008
  • Bharathi K. Study of hematological profile and its significance in type 2 diabetes mellitus patients. J Diagn Pathol Oncol. 2016;1:14–17.
  • Adane T, Getaneh Z, Asrie F. Red blood cell parameters and their correlation with renal function tests among diabetes mellitus patients: a comparative cross-sectional study. Diabetes Metab Syndrome Obesity. 2020;13:3937. doi:10.2147/DMSO.S275392
  • Grossmann M, Panagiotopolous S, Sharpe K, et al. Low testosterone and anaemia in men with type 2 diabetes. Clin Endocrinol (Oxf). 2009;70(4):547–553. doi:10.1111/j.1365-2265.2008.03357.x
  • Church TS, LaMonte MJ, Barlow CE, Blair SN. Cardiorespiratory fitness and body mass index as predictors of cardiovascular disease mortality among men with diabetes. Arch Intern Med. 2005;165(18):2114–2120. doi:10.1001/archinte.165.18.2114
  • Nesti L, Pugliese NR, Sciuto P, Natali A. Type 2 diabetes and reduced exercise tolerance: a review of the literature through an integrated physiology approach. Cardiovasc Diabetol. 2020;19(1):1–17. doi:10.1186/s12933-020-01109-1
  • Arkew M, Yemane T, Mengistu Y, Gemechu K, Tesfaye G. Hematological parameters of type 2 diabetic adult patients at Debre Berhan Referral Hospital, Northeast Ethiopia: a comparative cross-sectional study. PLoS One. 2021;16(6):e0253286. doi:10.1371/journal.pone.0253286
  • Tong PC, Lee K-F, So W-Y, et al. White blood cell count is associated with macro-and microvascular complications in Chinese patients with type 2 diabetes. Diabetes Care. 2004;27(1):216–222. doi:10.2337/diacare.27.1.216
  • Kakouros N, Rade JJ, Kourliouros A, Resar JR. Platelet function in patients with diabetes mellitus: from a theoretical to a practical perspective. Int J Endocrinol. 2011;2011:487.
  • Ferreiro JL, Gómez-Hospital JA, Angiolillo DJ. Platelet abnormalities in diabetes mellitus. Diabetes Vascular Dis Res. 2010;7(4):251–259. doi:10.1177/1479164110383994
  • Santilli F, Simeone P, Liani R. The Role of Platelets in Diabetes Mellitus. Platelets: Elsevier; 2019:469–503.
  • Adane T, Asrie F, Getaneh Z, Getawa S. White blood cells and platelet profiles of diabetic patients at University of Gondar specialized referral hospital: a comparative cross‐sectional study. J Clin Lab Anal. 2021;35(6):e23808. doi:10.1002/jcla.23808
  • Yngen M, Östenson C, Li N, Hjemdahl P, Wallen N. Acute hyperglycemia increases soluble P-selectin in male patients with mild diabetes mellitus. Blood Coagulation Fibrinolysis. 2001;12(2):109–116. doi:10.1097/00001721-200103000-00004
  • Undas A, Wiek I, Stêpien E, Zmudka K, Tracz W. Hyperglycemia is associated with enhanced thrombin formation, platelet activation, and fibrin clot resistance to lysis in patients with acute coronary syndrome. Diabetes Care. 2008;31(8):1590–1595. doi:10.2337/dc08-0282