Analysis of JAK2V617F Tyrosine Kinase Mutation in Blood Donors with Erythrocytosis – A Pilot Study in a Tertiary Care Teaching Hospital of South India

References

• Myers DJ, Collins RA. Blood donation. StatPearls; 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK525967/. Accessed July 27, 2022.
   Google Scholar
• Tagariello G, Di Gaetano R, Sartori R, et al. The JAK2(V617F) tyrosine kinase mutation in blood donors with upper-limit haematocrit levels. Blood Transfus. 2009;7(2):111–116. doi:10.2450/2008.0049-08
   PubMed Web of Science ®Google Scholar
• Mithoowani S, Laureano M, Crowther MA, Hillis CM. Investigation and management of erythrocytosis. CMAJ. 2020;192(32):E913–E918. doi:10.1503/cmaj.191587
   PubMed Web of Science ®Google Scholar
• Barbui T, Thiele J, Gisslinger H, et al. The 2016 WHO classification and diagnostic criteria for myeloproliferative neoplasms: document summary and in-depth discussion. Blood Cancer J. 2018;8(2):15. doi:10.1038/s41408-018-0054-y
   PubMed Web of Science ®Google Scholar
• Kamaruzzaman SF, Noor NH, Hassan MN, Yusoff SM, Abdullah WZ. Detection of JAK2 V617F mutation among donors with erythrocytosis. Am J Med Sci. 2018;3(2):19–25. doi:10.24191/jchs.v3i2.7056
   Google Scholar
• Kumar V, Abbas AK, Aster JC. Red blood cell and bleeding disorders. Polycythemia. In: Robbins Basic Pathology. 10th ed. Elsevier Health Sciences; 2017:656.
   Google Scholar
• Messinezy M, Pearson TC. The classification and diagnostic criteria of the erythrocytoses (polycythaemias). Clin Lab Haematol. 1999;21(5):309–316. doi:10.1046/j.1365-2257.1999.00246.x
   PubMedGoogle Scholar
• Wouters HJ, Mulder R, van Zeventer IA, et al. Erythrocytosis in the general population: clinical characteristics and association with clonal hematopoiesis. Blood Adv. 2020;4(24):6353–6363. doi:10.1182/bloodadvances.2020003323
   PubMed Web of Science ®Google Scholar
• Ministry of Health and Family Welfare, Government of India, New Delhi. Guidelines for blood donor selection & referral –NACO; 2017. Available from: http://naco.gov.in/sites/default/files/Letter%20reg.%20%20guidelines%20for%20blood%20donor%20selection%20%26%20referral%20-2017.pdf. Accessed July 27, 2022
   Google Scholar
• Pisudde PM, Shyam S, Rekha D, Gon S. Evaluation of pre-donation deferral reason among the blood donors visiting ESIC hospital in Eastern India. J Blood Disord Transfus. 2015;6(250):2.
   Google Scholar
• Bobati S, Basavraj V, Prakash P. Analysis of predonation loss of blood donors due to deferrals-in a tertiary care hospital set up. J Health Allied Sci. 2016;5(1):15–18. doi:10.4103/2278-344X.173874
   Google Scholar
• Kandasamy D, Shastry S, Chenna D, Mohan G. Blood donor deferral analysis in relation to the screening process: a single-center study from southern India with emphasis on high hemoglobin prevalence. J Blood Med. 2020;11:327–334. doi:10.2147/JBM.S265461
   PubMed Web of Science ®Google Scholar
• Vyas N, Prakash Sapre J, Maheshbhai Maru A, Ramkrishna Shah A. Donor deferral criteria-one-year study at a tertiary care hospital. J Diagn Pathol Oncol. 2021;6(2):90–93. doi:10.18231/j.jdpo.2021.020
   Google Scholar
• Sabari Priya E. Retrospective analysis of patterns of donor deferral among blood donors in a tertiary care hospital. Int J Contemp Med Res. 2019;6(1):A6–A9.
   Google Scholar
• Hatami H, Maghsoodlu M, Salehifar P, Karimian M, Ferdowsi S. Analyzing the causes of blood donor deferrals and characteristics of deferred individuals in Kurdistan Province, Iran. Int J Basic Sci Med. 2018;3(3):114–119. doi:10.15171/ijbsm.2018.21
   Google Scholar
• Al-Nuri RN. The frequency of blood donors and polycythemia among general population in Nineveh Governorate, Iraq. Ann Coll Med Mosul. 2021;42(2):141–147. doi:10.33899/mmed.2020.128424.1049
   Google Scholar
• Arslan O. Whole blood donor deferral rate and characteristics of the Turkish population. Transfus Med. 2007;17(5):379–383. doi:10.1111/j.1365-3148.2007.00738.x
   PubMed Web of Science ®Google Scholar
• Magnussen K, Hasselbalch HC, Ullum H, Bjerrum OW. Characterization of blood donors with high haemoglobin concentration. Vox Sang. 2013;104(2):110–114. doi:10.1111/j.1423-0410.2012.01644.x
   PubMed Web of Science ®Google Scholar
• Birjandi F, Gharehbaghian A, Delavari A, Rezaie N, Maghsudlu M. Blood donor deferral pattern in Iran. Arch Iran Med. 2013;16(11):657–660.
   PubMed Web of Science ®Google Scholar
• Sultan S, Irfan SM, Baig MA, Usman SM, Shirazi UA. Insight into donor deferral pattern based on peripheral blood counts: an experience from South Pakistan. Asian J Transfus Sci. 2017;11(2):151–155. doi:10.4103/0973-6247.214357
   PubMedGoogle Scholar
• Ibrahim IK, Hassan R, Ali EW, Omer A. Polycythaemia vera among sudanese patients with special emphasis on JAK2 mutations. Asian Pac J Cancer Prev. 2019;20(1):41–44. doi:10.31557/APJCP.2019.20.1.41
   PubMedGoogle Scholar
• Djulbegovic M, Dugdale LS, Lee AI. Evaluation of polycythemia: a teachable moment. JAMA Intern Med. 2018;178(1):128–130. doi:10.1001/jamainternmed.2017.6213
   PubMed Web of Science ®Google Scholar
• AL-Rubaie HA, Khudeir MA, Al-Bayaa IM. Detection of JAK2V617F tyrosine kinase mutation and estimation of serum erythropoietin in blood donors who have high hematocrit. J Fac Med Baghdad. 2014;56(4):395–400. doi:10.32007/med.1936/jfacmedbagdad.v56i4.12
   Google Scholar
• Gangat N, Szuber N, Pardanani A, Tefferi A. JAK2 unmutated erythrocytosis: current diagnostic approach and therapeutic views. Leukemia. 2021;35(8):2166–2181. doi:10.1038/s41375-021-01290-6
   PubMed Web of Science ®Google Scholar
• Prchal JF, Prchal JT, Polycythemia V, et al. Williams Hematology. 9th ed. New York: McGraw-Hill; 2021:1291–1301.
   Google Scholar
• Vannucchi AM. From leeches to personalized medicine: evolving concepts in the management of polycythemia vera. Haematologica. 2017;102(1):18–29. doi:10.3324/haematol.2015.129155
   PubMed Web of Science ®Google Scholar
• Lupak O, Han X, Xie P, Mahmood S, Mohammed H, Donthireddy V. The role of a low erythropoietin level for the polycythemia vera diagnosis. Blood Cells Mol Dis. 2020;80:102355. doi:10.1016/j.bcmd.2019.102355
   PubMed Web of Science ®Google Scholar