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Original Research

Alpha-Mangostin Improves Cardiac Hypertrophy and Fibrosis and Associated Biochemical Parameters in High-Fat/High-Glucose Diet and Low-Dose Streptozotocin Injection-Induced Type 2 Diabetic Rats

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Pages 27-38 | Published online: 28 Jan 2020

References

  • De Rosa S, Arcidiacono B, Chiefari E, et al. Type 2 diabetes mellitus and cardiovascular disease: genetic and epigenetic links. Front Endocrinol (Lausanne). 2018;17(9):2. doi:10.3389/fendo.2018.00002
  • Stumvoll M, Goldstein BJ, van Haeften TW. Type 2 diabetes: principles of pathogenesis and therapy. Lancet. 2005;365(9467):1333–1346. doi:10.1016/S0140-6736(05)61032-X
  • Vecchié A, Montecucco F, Carbone F, et al. Diabetes and vascular disease: is it all about glycemia? Curr Pharm Des. 2019;25(29):3112–3127. doi:10.2174/1381612825666190830181944
  • Jia G, Hill MA, Sowers JR. Diabetic cardiomyopathy: an update of mechanisms contributing to this clinical entity. Circ Res. 2018;122(4):624–638. doi:10.1161/CIRCRESAHA.117.311586
  • Chen S, Guo X, Chen Y, et al. Prevalence of abnormal serum liver enzymes in patients with type 2 diabetes mellitus: a cross-sectional study from China. Postgrad Med. 2016;128(8):770–776. doi:10.1080/00325481.2016.1242366
  • Feig DI, Kang DH, Johnson RJ. Uric acid and cardiovascular risk. N Engl J Med. 2008;359(17):1811–1821. doi:10.1056/NEJMra0800885
  • Bell DS. Heart failure: the frequent, forgotten, and often fatal complication of diabetes. Diabetes Care. 2003;26(8):2433–2441. doi:10.2337/diacare.26.8.2433
  • Ferrannini E, Cushman WC. Diabetes and hypertension: the bad companions. Lancet. 2012;380(9841):601–610. doi:10.1016/S0140-6736(12)60987-8
  • Hunking P. Lifestyle advice in preventing and treating type 2 diabetes. J Fam Health. 2005;16:109e12.
  • Milajerdi A, Jazayeri S, Hashemzadeh N, et al. The effect of saffron (Crocus sativus L.) hydroalcoholic extract on metabolic control in type 2 diabetes mellitus: a triple-blinded randomized clinical trial. J Res Med Sci. 2018;23:16. doi:10.4103/jrms.JRMS_286_17
  • World Health Organization (WHO). The WHO expert committee on diabetes mellitus, Technical Report Series 646. Geneva, Switzerland; 1980.
  • Keputusan Menteri Kesehatan Republik Indonesia Nomor 0584/Menkes/SK/VI/1995 Tentang Sentra Pengembangan dan Penerapan Pengobatan Tradisional; 1995.
  • Laksmiani NPL. Ethanolic extract of mangosteen (Garcinia mangostana) pericarp as sensitivity enhancer of doxorubicin on MCF-7 cells by inhibiting P-glycoprotein. Nus Biosci. 2019;11(1):49–55.
  • Adenina S, Rahmaniah R, Yuyuntia Y, et al. The effect of alpha-mangostin on transforming growth factor beta 1 (TGF-β1) and matrix metalloproteinase-3 expression in TGF-β-induced hepatic stellate cells. Int J App Pharm. 2019;11(1):177–180. doi:10.22159/ijap.2019.v11s1.16144
  • Chen LG, Yang LL, Wang CC. Anti-inflammatory activity of mangostins from Garcinia mangostana. Food Chem Toxicol. 2008;46(2):688–693. doi:10.1016/j.fct.2007.09.096
  • Pedraza-Chaverrí J, Reyes-Fermín LM, Nolasco-Amaya EG, et al. ROS scavenging capacity and neuroprotective effect of α-mangostin against 3-nitropropionic acid in cerebellar granule neurons. Exp Toxicol Pathol. 2009;61(5):491–501. doi:10.1016/j.etp.2008.11.002
  • Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412–419. doi:10.1007/BF00280883
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25:402–408. doi:10.1006/meth.2001.1262
  • Mekseepralard C, Areebambud C, Suksamrarn S, et al. Effects of long-term alpha-mangostin supplementation on hyperglycemia and insulin resistance in type 2 diabetic rats induced by high fat diet and low dose streptozotocin. J Med Assoc Thai. 2015;98(Suppl 10):S23–S30.
  • Jariyapongskul A, Areebambud C, Suksamrarn S, et al. Alpha-mangostin attenuation of hyperglycemia-induced ocular hypoperfusion and blood retinal barrier leakage in the early stage of type 2 diabetes rats. Biomed Res Int. 2015;2015:785826. doi:10.1155/2015/785826
  • Gothandam K, Ganesan VS, Ayyasamy T, et al. Antioxidant potential of theaflavin ameliorates the activities of key enzymes of glucose metabolism in high fat diet and streptozotocin-induced diabetic rats. Redox Rep. 2019;24(1):41–50. doi:10.1080/13510002.2019.1624085
  • Ginsberg HN. Insulin resistance and cardiovascular disease. J Clin Invest. 2000;106(4):453–458. doi:10.1172/JCI10762
  • Grundy SM, Hansen B, Smith SC, et al. Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Arterioscler Thromb Vasc Biol. 2004;24(2):e19–e24. doi:10.1161/01.ATV.0000112379.88385.67
  • Singh N, Kamath V, Rajini PS. Attenuation of hyperglycemia and associated biochemical parameters in STZ-induced diabetic rats by dietary supplementation of potato peel powder. Clin Chim Acta. 2005;353(1–2):165–175. doi:10.1016/j.cccn.2004.10.016
  • Bratoeva K, Stoyanov GS, Merdzhanova A, et al. Manifestations of renal impairment in fructose-induced metabolic syndrome. Cureus. 2017;9(11):e1826.
  • Buettner R, Parhofer KG, Woenckhaus M, et al. Defining high-fat-diet rat models: metabolic and molecular effects of different fat types. J Mol Endocrinol. 2006;36(3):485–501. doi:10.1677/jme.1.01909
  • Oliveira GO, Braga CP, Fernandes AA. Improvement of biochemical parameters in type 1diabetic rats after the roots aqueous extract of yacon [Smallanthus sonchifolius (Poepp.& Endl.)] treatment. Food Chem Toxicol. 2013;59:256–260. doi:10.1016/j.fct.2013.05.050
  • Vozarova B, Stefan N, Lindsay RS, et al. High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes. 2002;51(6):1889–1895. doi:10.2337/diabetes.51.6.1889
  • Ghimire S, Shakya S, Shakya J. Abnormal liver parameters among individuals with type 2 diabetes mellitus Nepalese population. Biochem Pharmacol (Los Angel). 2018;7:1. doi:10.4172/2167-0501.1000243
  • Judi L, Toukan A, Khader Y, et al. Prevalence of elevated hepatic transaminases among Jordanian patients with type 2 diabetes mellitus. Ann Saudi Med. 2010;30(1):25–32. doi:10.5144/0256-4947.59369
  • Arkkila PE, Koskinen PJ, Kantola IM, et al. Diabetic complications are associated with liver enzyme activities in people with type 1 diabetes. Diabetes Res Clin Pract. 2001;52(2):113–118. doi:10.1016/S0168-8227(00)00241-2
  • Quiñones Galvan A, Natali A, Baldi S, et al. Effect of insulin on uric acid excretion in humans. Am J Physiol. 1995;268(1 Pt 1):E1–E5. doi:10.1152/ajpendo.1995.268.1.E1
  • Choi SS, Diehl AM. Hepatic triglyceride synthesis and nonalcoholic fatty liver disease. Curr Opin Lipidol. 2008;19(3):295–300. doi:10.1097/MOL.0b013e3282ff5e55
  • Lee JH. Prevalence of hyperuricemia and its association with metabolic syndrome and cardiometabolic risk factors in Korean children and adolescents: analysis based on the 2016–2017 Korea National Health and Nutrition Examination Survey. Korean J Pediatr. 2019;62(8):317–323. doi:10.3345/kjp.2019.00444
  • Kwong RY, Sattar H, Wu H, et al. Incidence and prognostic implication of unrecognized myocardial scar characterized by cardiac magnetic resonance in diabetic patients without clinical evidence of myocardial infarction. Circulation. 2008;118(100):1011–1020. doi:10.1161/CIRCULATIONAHA.107.727826
  • Turkbey EB, Backlund JY, Genuth S, et al. DCCT/EDIC Research Group. Myocardial structure, function, and scar in patients with type 1 diabetes mellitus. Circulation. 2011;124(16):1737–1746. doi:10.1161/CIRCULATIONAHA.111.022327
  • Russo I, Frangogiannis NG. Diabetes-associated cardiac fibrosis: cellular effectors, molecular mechanisms and therapeutic opportunities. J Mol Cell Cardiol. 2016;90:84–93. doi:10.1016/j.yjmcc.2015.12.011
  • Nikolajević Starčević J, Janić M, Šabovič M. Molecular mechanisms responsible for diastolic dysfunction in diabetes mellitus patients. Int J Mol Sci. 2019;9(5):20.
  • Bienvenu LA, Morgan J, Rickard AJ, et al. Macrophage mineralocorticoid receptor signaling plays a key role in aldosterone-independent cardiac fibrosis. Endocrinology. 2012;153(7):3416–3425. doi:10.1210/en.2011-2098
  • Jia G, DeMarco VG, Sowers JR. Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy. Nat Rev Endocrinol. 2016;12(3):144–153. doi:10.1038/nrendo.2015.216
  • Badole SL, Chaudhari SM, Jangam GB, et al. Cardioprotective activity of pongamia pinnata in streptozotocin-nicotinamide induced diabetic rats. Biomed Res Int. 2015;2015:403291. doi:10.1155/2015/403291
  • Yang J, Park Y, Zhang H, et al. Role of MCP-1 in tumor necrosis factor-alpha-induced endothelial dysfunction in type 2 diabetic mice. Am J Physiol Heart Circ Physiol. 2009;297(4):H1208–H1216. doi:10.1152/ajpheart.00396.2009
  • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259(5091):87–91. doi:10.1126/science.7678183
  • Sampath PD, Vijayaragavan K. Ameliorative prospective of alpha-mangostin, a xanthone derivative from Garcinia mangostana against beta-adrenergic catecholamine-induced myocardial toxicity and anomalous cardiac TNF-alpha and COX-2 expressions in rats. Exp Toxicol Pathol. 2008;60(4–5):357–364. doi:10.1016/j.etp.2008.02.006
  • Xu Y, Zhou H, Cai L. Alpha-mangostin attenuates oxidative stress and inflammation in adjuvant-induced arthritic rats. Trop J Pharm Res. 2017;16(11):2611–2616. doi:10.4314/tjpr.v16i11.6