174
Views
7
CrossRef citations to date
0
Altmetric
Original Research

Chronic khat (Catha edulis) and alcohol marginally alter complete blood counts, clinical chemistry, and testosterone in male rats

, &
Pages 33-44 | Published online: 24 Jun 2013

References

  • AgeelyHMAHealth and socio-economic hazards associated with khat consumptionJ Family Community Med200815131123012161
  • Al-SamarraieMZ KhiabaniHOpdalMSKhat – a new drug of abuse in NorwayTidsskr Nor Laegeforen20071275574576 Norwegian17332809
  • NenciniPAhmedAMKhat consumption: a pharmacological reviewDrug Alcohol Depend198923119292537717
  • IhunwoAOKayanjaFIBAmadi-IhunwoUBUse and perception of the psychostimulant, khat (catha edulis) among three occupational groups in south western UgandaEast Afr Med J200481946847315626057
  • AndersonDBeckerlegSHailuDKleinAThe Khat Controversy: Stimulating the Debate on DrugsOxfordBerg Publishers2007
  • BeckerlegSKhat chewing as a new Ugandan leisure activityJournal of East African Studies2009314254
  • BeckerlegS“Idle and disorderly” khat users in Western UgandaDrugs: Education, Prevention, and Policy2010174303314
  • KebedeDAlemAMitikeGKhat and alcohol use and risky sex behaviour among in-school and out-of-school youth in EthiopiaBMC Public Health2005510916225665
  • ManghiRABroersBKhanRBenguettatDKhazaalYZullinoDFKhat use: lifestyle or addiction?J Psychoactive Drugs200941111019455904
  • HassanNAGunaidAAMurray-LyonIMKhat (Catha edulis): health aspects of khat chewingEast Mediterr Health J200713370671817687845
  • AliWMAl HabibKFAl-MotarrebAAcute coronary syndrome and khat herbal amphetamine use: an observational reportCirculation2011124242681268922155995
  • AliWMZubaidMAl-MotarrebAAssociation of khat chewing with increased risk of stroke and death in patients presenting with acute coronary syndromeMayo Clin Proc2010851197498020926835
  • Al-HaboriMThe potential adverse effects of habitual use of Catha edulis (khat)Expert Opin Drug Saf2005461145115416255671
  • Al-MotarrebAAl-HaboriMBroadleyKJKhat chewing, cardiovascular diseases and other internal medical problems: the current situation and directions for future researchJ Ethnopharmacol2010132354054820621179
  • ElmiASThe chewing of khat in SomaliaJ Ethnopharmacol1983821631766139513
  • IslamMWTariqMAgeelAMel-FeralyFSAl-MeshalIAAshrafIAn evaluation of the male reproductive toxicity of cathinoneToxicology19906032232342315943
  • MohammedAEngidaworkAReproductive parameters are differentially altered following subchronic administration of Catha edulis F. (Khat) extract and cathinone in male ratsJ Ethnopharmacol2011134397798321335082
  • World Health OrganizationGlobal Status Report on Alcohol and HealthGenevaWorld Health Organization2011 Available from: http://www.who.int/substance_abuse/publications/global_alcohol_report/msbgsruprofiles.pdfAccessed May 18, 2013
  • RoereckeMRehmJIschemic heart disease mortality and morbidity rates in former drinkers: a meta-analysisAm J Epidemiol2011173324525821156750
  • RehmJBaliunasDBorgesGLThe relation between different dimensions of alcohol consumption and burden of disease: an overviewAddiction2010105581784320331573
  • RehmJMathersCPopovaSThavorncharoensapMTeerawattananonYPatraJGlobal burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disordersLancet200937396822223223319560604
  • AlelePERujumbaJBKhat (Catha edulis) and ethanol co-dependence modulate seizure expression in a pentylenetetrazol seizure modelJ Ethnopharmacol201113731431143621871549
  • WidlerPMathysKBrenneisenRKalixPFischHUPharmaco-dynamics and pharmacokinetics of khat: a controlled studyClin Pharmacol Ther19945545565627910126
  • OdebiyiOOSofoworaEAPhytochemical screening of Nigerian medicinal plants IILloydia1991413234246672462
  • AlsalahiAAbdullaMAAl-MamaryMToxicological Features of Catha edulis (Khat) on Livers and Kidneys of Male and Female Sprague-Dawley Rats: A Subchronic StudyEvid Based Complement Alternat Med2012201282940123259000
  • DevaudLLMatthewsDBMorrowALGender impacts behavioral and neurochemical adaptations in ethanol-dependent ratsPharmacol Biochem Behav199964484184910593208
  • ElmiASKhat and blood glucose levels in manJ Ethnopharmacol1983833314.19836645581
  • HalbachHMedical aspects of the chewing of khat leavesBull World Health Organ197247121294538902
  • ChappellJSLeeMMCathinone preservation in khat evidence via dryingForensic Sci Int20101951–310812020036789
  • AlmedoAMAbrahamSWomen, moral virtue and Tchat-chewingMcDonaldMGender, Drink and DrugsOxfordBerg Publishers1994249259
  • HeatherNMillerWRGreeleyJSelf-Control and the Addictive BehavioursSydney, AustraliaMaxwell MacMillan1991
  • Al-MamaryMAl-HaboriMAl-AghbariAMBakerMMInvestigation into the toxicological effects of Catha edulis leaves: a short term study in animalsPhytother Res200216212713211933113
  • NemzekJABolgosGLWilliamsBARemickDGDifferences in normal values for murine white blood cell counts and other hematological parameters based on sampling siteInflamm Res2001501052352711713907
  • GothelfAHojmanPGehlJChange in hemoglobin levels due to anesthesia in mice: an important confounder in studies on hematopoietic drugsBiol Proced Online200911132533019957064
  • Al-HaboriMAl-AghbariAAl-MamaryMBakerMToxicological evaluation of Catha edulis leaves: a long term feeding experiment in animalsJ Ethnopharmacol200283320921712426088
  • Al-HaboriMAl-MamaryMLong-term feeding effects of Catha edulis leaves on blood constituents in animalsPhytomedicine2004117–863964415636178
  • ApterSJErikssonCJThe effect of alcohol on testosterone concentrations in alcohol-preferring and non-preferring rat linesAlcohol Clin Exp Res20032771190119312878927
  • CiceroTJBadgerTMEffects of alcohol on the hypothalamic-pituitarygonadal axis in the male ratJ Pharmacol Exp Ther19772012427433870681
  • AlomaryAAValléeMO’DellLEKoobGFPurdyRHFitzgeraldRLAcutely administered ethanol participates in testosterone synthesis and increases testosterone in rat brainAlcohol Clin Exp Res2003271384312544003
  • GebissaEScourge of Life or an Economic Lifeline? Public Discourses on Khat (Catha edulis) in EthiopiaSubst Use Misuse200843678480218473222
  • BeckerlegSWhat harm? Kenyan and Ugandan perspectives on khatAfrican Affairs2006105419219241
  • OsolAFarrarGEThe Dispensatory of the United States of America25th edPhiladelphia, PAJB Lippincott Company1955
  • NenciniPAhmedAMElmiASSubjective effects of khat chewing in humansDrug Alcohol Depend1986181971052877839
  • World Health OrganizationGlobal survey of alcohol and health. Management of substance abuseWorld Health Organization2010 Available from: http://www.who.int/substance_abuse/en/Accessed May 5, 2013