References
- GoodmanZDIshakKGLanglossJMSesterhennIARabinLCombined hepatocellular-cholangiocarcinoma. A histologic and immunohistochemical studyCancer19855511241352578078
- BosmanFTCarneiroFHrubanRTheiseNDWHO Classification of Tumours of the Digestive SystemIARC PressLyon2010
- KohKCLeeHChoiMSClinicopathologic features and prognosis of combined hepatocellular cholangiocarcinomaAm J Surg2005189112012515701504
- AllenRALisaJRCombined liver cell and bile duct carcinomaAm J Pathol194925464765518152860
- WachtelMSZhangYXuTChiriva-InternatiMFrezzaEECombined hepatocellular cholangiocarcinomas; analysis of a large databaseClin Med Pathol20081S500S547
- JarnaginWRWeberSTickooSKCombined hepatocellular and cholangiocarcinoma: demographic, clinical, and prognostic factorsCancer20029472040204611932907
- BruntEAishimaSClavienPAcHCC-CCA: consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentiationHepatology201868111312629360137
- WangAQZhengYCDuJCombined hepatocellular cholan-giocarcinoma: controversies to be addressedWorld J Gastroenterol201622184459446527182157
- KimHParkCHanKHPrimary liver carcinoma of intermediate (hepatocyte–cholangiocyte) phenotypeJ Hepatol200440229830414739102
- ZhangFChenXPZhangWCombined hepatocellular chol-angiocarcinoma originating from hepatic progenitor cells: immuno-histochemical and double-fluorescence immunostaining evidenceHistopathology200852222423218184271
- LeeWSLeeKWHeoJSComparison of combined hepatocellular and cholangiocarcinoma with hepatocellular carcinoma and intrahepatic cholangiocarcinomaSurg Today2006361089289716998683
- ZuoHQYanLNZengYClinicopathological characteristics of 15 patients with combined hepatocellular carcinoma and cholangiocar-cinomaHepatobiliary Pancreat Dis Int20076216116517374575
- LeeCHHsiehSYChangCJLinYJComparison of clinical characteristics of combined hepatocellular-cholangiocarcinoma and other primary liver cancersJ Gastroenterol Hepatol201328112212723034166
- Cazals-HatemDRebouissouSBioulac-SagePClinical and molecular analysis of combined hepatocellular-cholangiocarcinomasJ Hepatol200441229229815288479
- LeeJHChungGEYuSJLong-term prognosis of combined hepatocellular and cholangiocarcinoma after curative resection comparison with hepatocellular carcinoma and cholangiocarcinomaJ Clin Gastroenterol2011451697520142755
- YoonYIHwangSLeeYJPostresection outcomes of combined hepatocellular carcinoma-cholangiocarcinoma, hepatocellular carcinoma and intrahepatic cholangiocarcinomaJ Gastrointest Surg201620241142026628072
- YinXZhangBHQiuSJCombined hepatocellular carcinoma and cholangiocarcinoma: clinical features, treatment modalities, and prognosisAnn Surg Oncol20121992869287622451237
- GaranciniMGoffredoPPagniFCombined hepatocellular-cholangiocarcinoma: a population-level analysis of an uncommon primary liver tumorLiver Transpl201420895295924777610
- JungDHHwangSSongGWLongterm prognosis of combined hepatocellular carcinoma-cholangiocarcinoma following liver transplantation and resectionLiver Transpl201723333034128027599
- NgIOShekTWNichollsJMaLTCombined hepatocellular-chol-angiocarcinoma: a clinicopathological studyJ Gastroenterol Hepatol199813134409737569
- GhouriYAMianIRoweJHReview of hepatocellular carcinoma: epidemiology, etiology, and carcinogenesisJ Carcinog2017161128694740
- SanyalAJYoonSKLencioniRThe etiology of hepatocellular carcinoma and consequences for treatmentOncologist201015Suppl 4142221115577
- KhanSAToledanoMBTaylor-RobinsonSDEpidemiology, risk factors, and pathogenesis of cholangiocarcinomaHPB2008102778218773060
- TaguchiJNakashimaOTanakaMHisakaTTakazawaTKojiroMA clinicopathological study on combined hepatocellular and cholan-giocarcinomaJ Gastroenterol Hepatol19961187587648872774
- KassahunWTHaussJManagement of combined hepatocellular and cholangiocarcinomaInt J Clin Pract20086281271127818284443
- KimJHYoonHKKoGYNonresectable combined hepatocellular carcinoma and cholangiocarcinoma: analysis of the response and prognostic factors after transcatheter arterial chemoembolizationRadiology2010255127027720308463
- AokiKTakayasuKKawanoTCombined hepatocellular carcinoma and cholangiocarcinoma: clinical features and computed tomographic findingsHepatology1993185109010957693572
- YanoYYamamotoJKosugeTCombined hepatocellular and cholangiocarcinoma: a clinicopathologic study of 26 resected casesJpn J Clin Oncol200333628328712913082
- BhagatVJavleMYuJCombined hepatocholangiocarcinoma: case-series and review of literatureInt J Gastrointest Cancer2006371273417290078
- TickooSKZeeSYObiekweSCombined hepatocellular-cholangiocarcinoma: a histopathologic, immunohistochemical, and in situ hybridization studyAm J Surg Pathol200226898999712170085
- YehMMPathology of combined hepatocellular-cholangiocarcinomaJ Gastroenterol Hepatol20102591485149220796144
- TheiseNDYaoJLHaradaKHepatic “stem cell” malignancies in adults: four casesHistopathology200343326327112940779
- WuPCFangJWLauVKLaiCLLoCKLauJYClassification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers. Clinical and biological implicationsAm J Pathol19961494116711758863666
- MoeiniASiaDZhangZMixed hepatocellular cholangiocar-cinoma tumors: cholangiolocellular carcinoma is a distinct molecular entityJ Hepatol201766595296128126467
- FujiiHZhuXGMatsumotoTGenetic classification of combined hepatocellular-cholangiocarcinomaHum Pathol20003191011101711014564
- YanoHIemuraAHaramakiMA human combined hepatocellular and cholangiocarcinoma cell line (KMCH-2) that shows the features of hepatocellular carcinoma or cholangiocarcinoma under different growth conditionsJ Hepatol19962444134228738727
- MaedaTAdachiEKajiyamaKSugimachiKTsuneyoshiMCombined hepatocellular and cholangiocarcinoma: proposed criteria according to cytokeratin expression and analysis of clinicopathologic featuresHum Pathol19952699569647545644
- O’ConnorKWalshJCSchaefferDFCombined hepatocellular-cholangiocarcinoma (cHCC-CC): a distinct entityAnn Hepatol201413331732224756005
- GeraSEttelMAcosta-GonzalezGXuRClinical features, histology, and histogenesis of combined hepatocellular-cholangiocarcinomaWorld J Hepatol20179630030928293379
- ChoiBIHanJKKimYICombined hepatocellular and cholan-giocarcinoma of the liver: sonography, CT, angiography, and iodized-oil CT with pathologic correlationAbdom Imaging199419143468161902
- MaximinSGaneshanDMShanbhogueAKCurrent update on combined hepatocellular-cholangiocarcinomaEur J Radiol Open20141404826937426
- SammonJFischerSMenezesRMRI features of combined hepatocellular-cholangiocarcinoma versus mass forming intrahepatic cholangiocarcinomaCancer Imaging2018181829486800
- FowlerKJSheybaniAParkerRA3rdCombined hepatocellular and cholangiocarcinoma (biphenotypic) tumors: imaging features and diagnostic accuracy of contrast-enhanced CT and MRIAm J Roent-genol20132012332339
- WellsMLVenkateshSKChandanVSBiphenotypic hepatic tumors: imaging findings and review of literatureAbdom Imaging20154072293230525952572
- ParkSHLeeSSYuECombined hepatocellular-cholangiocarcinoma: gadoxetic acid-enhanced MRI findings correlated with pathologic features and prognosisJ Magn Reson Imaging201746126728027875000
- SanadaYShiozakiSAokiHTakakuraNYoshidaKYamaguchiYA clinical study of 11 cases of combined hepatocellular–cholangiocarcinoma: assessment of enhancement patterns on dynamics computed tomography before resectionHepatol Res200532318519515978872
- JeonSKJooILeeDHCombined hepatocellular cholangiocarcinoma: LI-RADS v2017 categorisation for differential diagnosis and prognostication on gadoxetic acid-enhanced MR imagingEur Radiol Epub2018628
- PotretzkeTATanBRDoyleMBBruntEMHeikenJPFowlerKJImaging features of biphenotypic primary liver carcinoma (hepatochol-angiocarcinoma) and the potential to mimic hepatocellular carcinoma: LI-RADS analysis of CT and MRI features in 61 casesAm J Roentgenol20162071253126866746
- HeCMaoYWangJThe Predictive value of staging systems and inflammation scores for patients with combined hepatocellular cholangiocarcinoma after surgical resection: a retrospective studyJ Gastrointest Surg20182271239125029667093
- YouHLWengSWLiSHCopy number aberrations in combined hepatocellular carcinoma and cholangiocarcinomaExp Mol Pathol201292328128622366251
- LiuZHLianBFDongQZWhole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversityBio-chim Biophys Acta186420186 Pt B23602368
- XueTCZhangBHYeSLRenZGDifferentially expressed gene profiles of intrahepatic cholangiocarcinoma, hepatocellular carcinoma, and combined hepatocellular-cholangiocarcinoma by integrated microarray analysisTumor Biol201536858915899
- SasakiMSatoYNakanumaYMutational landscape of combined hepatocellular carcinoma and cholangiocarcinoma, and its clinico-pathological significanceHistopathology201770342343427634656
- The Cancer Genome Atlas Research NetworkComprehensive and integrative genomic characterization of hepatocellular carcinomaCell2017169713271341.e2328622513
- WooHGLeeJHYoonJHIdentification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinomaCancer Res20107083034304120395200
- CoulouarnCCavardCRubbia-BrandtLCombined hepa-tocellular-cholangiocarcinomas exhibit progenitor features and activation of Wnt and TGFbeta signaling pathwaysCarcinogenesis20123391791179622696594
- DecaensTGodardCde ReynièsAStabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fateHepatology200847124725818038450
- TanXYuanYZengGBeta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse developmentHepatology20084751667167918393386
- KimKHLeeSGParkEHSurgical treatments and prognoses of patients with combined hepatocellular carcinoma and cholangiocarci-nomaAnn Surg Oncol200916362362919130133
- NakamuraSSuzukiSSakaguchiTSurgical treatment of patients with mixed hepatocellular carcinoma and cholangiocarcinomaCancer1996788167116768859179
- SasakiAKawanoKAramakiMClinicopathologic study of mixed hepatocellular and cholangiocellular carcinoma: modes of spreading and choice of surgical treatment by reference to macroscopic typeJ Surg Oncol2001761374611223823
- ErcolaniGGraziGLRavaioliMThe role of lymphadenectomy for liver tumors: further considerations on the appropriateness of treatment strategyAnn Surg2004239220220914745328
- BismuthHMajnoPEHepatobiliary surgeryJ Hepatol2000321 Suppl20822410728806
- TaoCYLiuWRJinLSurgical treatment of combined hepato-cellular-cholangiocarcinoma is as effective in elderly patients as it is in younger patients: a propensity score matching analysisJ Cancer2018961106111229581790
- NorthupPGWanamakerRCLeeVDAdamsRBBergCLModel for End-Stage Liver Disease (MELD) predicts nontransplant surgical mortality in patients with cirrhosisAnn Surg2005242224425116041215
- MalinchocMKamathPSGordonFDPeineCJRankJTer BorgPCA model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shuntsHepatology200031486487110733541
- GroeschlRTTuragaKKGamblinTCTransplantation versus resection for patients with combined hepatocellular carcinoma-cholangiocarci-nomaJ Surg Oncol2013107660861223386397
- VilchezVShahMBDailyMFLong-term outcome of patients undergoing liver transplantation for mixed hepatocellular carcinoma and cholangiocarcinoma: an analysis of the UNOS databaseHPB2016181293426776848
- ParkYHHwangSAhnCSLong-term outcome of liver transplantation for combined hepatocellular carcinoma and cholangiocarcinomaTranspl Proc201345830383040
- SongSMoonHHLeeSComparison between resection and transplantation in combined hepatocellular and cholangiocarcinomaTranspl Proc201345830413046
- BergquistJRGroeschlRTIvanicsTMixed hepatocellular and cholangiocarcinoma: a rare tumor with a mix of parent phenotypic characteristicsHPB2016181188689227546172
- MagantyKLeviDMoonJCombined hepatocellular carcinoma and intrahepatic cholangiocarcinoma: outcome after liver transplantationDig Dis Sci201055123597360120848202
- WuCHYongCCLiewEHCombined hepatocellular carcinoma and cholangiocarcinoma: diagnosis and prognosis after resection or transplantationTranspl Proc201648411001104
- MagistriPTarantinoGSerraVGuidettiCBallarinRdi BenedettoFLiver transplantation and combined hepatocellular-cholangiocarcinoma: feasibility and outcomesDig Liver Dis201749546747028258929
- FowlerKSaadNEBruntEBiphenotypic primary liver carcinomas: assessing outcomes of hepatic directed therapyAnn Surg Oncol201522134130413726293835
- de VitoCSarkerDRossPHeatonNQuagliaAHistological heterogeneity in primary and metastatic classic combined hepatocellular-cholangiocarcinoma: a case seriesVirchows Archiv2017471561962928707055
- NaSKChoiGHLeeHCThe effectiveness of transarterial chemoembolization in recurrent hepatocellular-cholangiocarcinoma after resectionPLoS One2018136e019813829879137
- KobayashiSTerashimaTShibaSMulticenter retrospective analysis of systemic chemotherapy for unresectable combined hepatocellular and cholangiocarcinomaCancer Sci201810982549255729856900
- RogersJEBolonesiRMRashidASystemic therapy for unresectable, mixed hepatocellular-cholangiocarcinoma: treatment of a rare malignancyJ Gastrointest Oncol20178234735128480073
- ChiMMikhitarianKShiCGoffLWManagement of combined hepatocellular-cholangiocarcinoma: a case report and literature reviewGastrointest Cancer Res20125619920223293701
- KimGMJeungH-CKimDA case of combined hepatocellular-cholangiocarcinoma with favorable response to systemic chemotherapyCancer Res Treat201042423523821253326
- BroutierLMastrogiovanniGVerstegenMMHuman primary liver cancer-derived organoid cultures for disease modeling and drug screeningNat Med201723121424143529131160
- SprinzlMFGallePRCurrent progress in immunotherapy of hepatocellular carcinomaJ Hepatol201766348248428011330
- DuffyAGUlahannanSVMakorova-RusherOTremelimumab in combination with ablation in patients with advanced hepatocellular carcinomaJ Hepatol201766354555127816492
- LiuCLFanSTLoCMHepatic resection for combined hepato-cellular and cholangiocarcinomaArch Surg20031381869012511158