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ORIGINAL RESEARCH

Presence of Hepatocellular Carcinoma Does Not Affect Course and Response to Anticoagulation of Bland Portal Vein Thrombosis in Cirrhotic Patients

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Pages 473-482 | Received 27 Oct 2022, Accepted 15 Mar 2023, Published online: 27 Mar 2023

References

  • Andriulli A, Tripodi A, Angeli P.; Under the Auspices of the Italian Association for the Study of Liver Diseases (AISF) and the Italian Society of Internal Medicine (SIMI). Hemostatic balance in patients with liver cirrhosis: report of a consensus conference. Dig Liver Dis. 2016;48(5):455–467. doi:10.1016/j.dld.2016.02.008
  • Tsochatzis EA, Senzolo M, Germani G, et al. Systematic review: portal vein thrombosis in cirrhosis. Aliment Pharmacol Ther. 2010;31(3):366–374. doi:10.1111/j.1365-2036.2009.04182.x
  • Violi F, Corazza RG, Caldwell SH, et al. Portalvein thrombosis relevance on liver cirrhosis: Italian Venous Thrombotic Events Registry. Intern Emerg Med. 2016;11:1059–1066. doi:10.1007/s11739-016-1416-8
  • von Kockritz L, De Gottardi A, Trebicka J, Praktiknjo M. Portal vein thrombosis in patients with cirrhosis. Gastroenterol Rep. 2017;5(2):148–156. doi:10.1093/gastro/gox014
  • Mahé I, Chidiac J, Bertoletti L, et al.; RIETE investigators. The clinical course of venousthromboembolism may differ to cancer site. Am J Med. 2017;130(3):337–347. doi:10.1016/j.amjmed.2016.10.017
  • Prins MH, Lensing AWA, Brighton TA, et al. Oral rivaroxaban versus enoxaparin with vitamin Kantagonist for the treatment of symptomatic venousthromboembolism in patients with cancer (EINSTEIN-DVTand EINSTEIN-PE): a pooled subgroup analysis of two randomised controlled trials. Lancet Haematol. 2014;1(1):e37–e46. doi:10.1016/S2352-3026(14)70018-3
  • Nery F, Chevret S, Condat B, et al. Causes and consequences of portal vein thrombosis in 1243 patients with cirrhosis: results of a longitudinal study. Hepatology. 2015;61:660–667. doi:10.1002/hep.27546
  • Villa E, Cammà C, Marietta M, et al. Enoxaparin prevents portal vein thrombosis and liver decompensation in patients with advanced cirrhosis. Gastroenterology. 2012;143:1253–1260. doi:10.1053/j.gastro.2012.07.018
  • Pettinari I, Vukotic R, Stefanescu H, et al.; BO-LIVES (Bologna LIVErvascular Studies). Clinical impact and safety of anticoagulants for portal vein thrombosis in chirrhosis. Am J Gastroenterol. 2019;114(2):258–266. doi:10.1038/s41395-018-0421-0
  • Piscaglia F, Gianstefani A, Ravaioli M, et al. Criteria for diagnosing benign portal vein thrombosis in the assessment of patients with cirrhosis and hepatocellular carcinoma for liver transplantation. Liver Transpl. 2010;16:658–667. doi:10.1002/lt.22044
  • Lip GY, Chin BS, Blann AD. Cancer and the prothrombotic state. Lancet Oncol. 2002;3(1):27–34. PMID: 11908507. doi:10.1016/s1470-2045(01)00619-2
  • Lai CH, Cheng PY, Chen YY. Liver cirrhosis and risk ofintracerebral haemorrhage: a 9-year follow-up study. Stroke. 2011;42:2615–2617. doi:10.1161/STROKEAHA.111.617076
  • Mancuso A, Politi F, Maringhini A. Portal vein thromboses in cirrhosis: to treat or not to treat? Gastroenterology. 2018;154:758. doi:10.1053/j.gastro.2017.07.053
  • Piscaglia F, Sansone V. Reply to anticoagulation for portal vein thrombosis in cirrhosis. Am J Gastroenterol. 2019;114(6):1001–1002. doi:10.14309/ajg.0000000000000274
  • Chak EW. Anticoagulation of portal vein thrombosis in cirrhosis: first, do no harm. Am J Gastroenterol. 2019. doi:10.14309/ajg.0000000000000351
  • European Association for the Study of the Liver. EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis. J Hepatol. 2022;76(5):1151–1184. PMID: 35300861. doi:10.1016/j.jhep.2021.09.003
  • Hanafy AS, Abd-Elsalam S, Dawoud MM. Randomized controlled trial of rivaroxaban versus warfarin in the management of acute non-neoplastic portal vein thrombosis. Vascul Pharmacol. 2019;113:86–91. PMID: 29886103. doi:10.1016/j.vph.2018.05.002
  • Loffredo L, Pastori D, Farcomeni A, Violi F. Effects of anticoagulants in patients with cirrhosis and portal vein thrombosis: a systematic review and meta-analysis. Gastroenterology. 2017;153:480–487. doi:10.1053/j.gastro.2017.04.042
  • Turon F, Hernández-Gea V, García-Pagán JC. Portal vein thrombosis: yes or no on anticoagulation therapy. Curr Opin Organ Transplant. 2018;23:250–256. doi:10.1097/MOT.0000000000000506
  • Piscaglia F, Benevento F, Pecorell A, Forgione A, Stefanescu H. Anticoagulation in cirrhotic portal vein thrombosis: no harm, but survival benefit still unclear. Am J Gastroenterol. 2020;115(1):145–146. PMID: 31809302. doi:10.14309/ajg.0000000000000483
  • Mahmoudi TM, Marquez V, Kayal A, Carvalho R, Weiss AA HCC complicated by PVT: outcome and the role of anticoagulation therapy. Can Liver J 2019;27:121–126. doi:10.3138/canlivj.2018-0026