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ORIGINAL RESEARCH

LINC00886 Facilitates Hepatocellular Carcinoma Tumorigenesis by Sequestering microRNA-409-3p and microRNA-214-5p

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Pages 863-881 | Received 02 Mar 2023, Accepted 01 Jun 2023, Published online: 08 Jun 2023

References

  • Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–249. doi:10.3322/caac.21660
  • Llovet JM, Kelley RK, Villanueva A, et al. Hepatocellular carcinoma. Nat Rev Dis Primer. 2021;7(1):6. doi:10.1038/s41572-020-00240-3
  • Shao M, Wang Y, Dong H, et al. From liver fibrosis to hepatocarcinogenesis: role of excessive liver H2O2 and targeting nanotherapeutics. Bioact Mater. 2023;23:187–205. doi:10.1016/j.bioactmat.2022.11.001
  • Fujiwara N, Friedman SL, Goossens N, Hoshida Y. Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine. J Hepatol. 2018;68(3):526–549. doi:10.1016/j.jhep.2017.09.016
  • Nakagawa S, Wei L, Song WM, et al. Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition. Cancer Cell. 2016;30(6):879–890. doi:10.1016/j.ccell.2016.11.004
  • Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. The Lancet. 2012;379(9822):1245–1255. doi:10.1016/S0140-6736(11)61347-0
  • Derrien T, Johnson R, Bussotti G, et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 2012;22(9):1775–1789. doi:10.1101/gr.132159.111
  • Yao RW, Wang Y, Chen LL. Cellular functions of long noncoding RNAs. Nat Cell Biol. 2019;21(5):542–551. doi:10.1038/s41556-019-0311-8
  • Jin S, Yang X, Li J, Yang W, Ma H, Zhang Z. p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma. Mol Cancer. 2019;18(1):38. doi:10.1186/s12943-019-0993-3
  • Xia R, Geng G, Yu X, et al. LINC01140 promotes the progression and tumor immune escape in lung cancer by sponging multiple microRNAs. J Immunother Cancer. 2021;9(8):e002746. doi:10.1136/jitc-2021-002746
  • Zhang Y, Miao Y, Shang M, et al. LincRNA-p21 leads to G1 arrest by p53 pathway in esophageal squamous cell carcinoma. Cancer Manag Res. 2019;11:6201–6214. doi:10.2147/CMAR.S197557
  • Li G-H, Ma Z-H, Wang X. Long non-coding RNA CCAT1 is a prognostic biomarker for the progression of oral squamous cell carcinoma via miR-181a-mediated Wnt/β-catenin signaling pathway. Cell Cycle. 2019;18(21):2902–2913. doi:10.1080/15384101.2019.1662257
  • Wu P, Mo Y, Peng M, et al. Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA. Mol Cancer. 2020;19(1):22. doi:10.1186/s12943-020-1147-3
  • Xie C, Li SY, Fang JH, Zhu Y, Yang JE. Functional long non-coding RNAs in hepatocellular carcinoma. Cancer Lett. 2021;500:281–291. doi:10.1016/j.canlet.2020.10.042
  • Lim LJ, Wong SYS, Huang F, et al. Roles and Regulation of Long Noncoding RNAs in Hepatocellular Carcinoma. Cancer Res. 2019;79(20):5131–5139. doi:10.1158/0008-5472.CAN-19-0255
  • Huang Z, Zhou JK, Peng Y, He W, Huang C. The role of long noncoding RNAs in hepatocellular carcinoma. Mol Cancer. 2020;19(1):77. doi:10.1186/s12943-020-01188-4
  • Pan W, Li W, Zhao J, et al. lnc RNA ‐ PDPK 2P promotes hepatocellular carcinoma progression through the PDK 1/ AKT /Caspase 3 pathway. Mol Oncol. 2019;13(10):2246–2258. doi:10.1002/1878-0261.12553
  • Sheng JQ, Wang MR, Fang D, et al. LncRNA NBR2 inhibits tumorigenesis by regulating autophagy in hepatocellular carcinoma. Biomed Pharmacother. 2021;133:111023. doi:10.1016/j.biopha.2020.111023
  • Zhao D, Zhang X, Tang Y, et al. Identification and Validation of Novel Biomarkers for Hepatocellular Carcinoma, Liver Fibrosis/Cirrhosis and Chronic Hepatitis B via Transcriptome Sequencing Technology. J Hepatocell Carcinoma. 2022;9:389–403. doi:10.2147/JHC.S357380
  • Angeli P, Bernardi M, Villanueva C, et al. EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis. J Hepatol. 2018;69(2):406–460. doi:10.1016/j.jhep.2018.03.024
  • Fukui H, Saito H, Ueno Y, et al. Evidence-based clinical practice guidelines for liver cirrhosis 2015. J Gastroenterol. 2016;51(7):629–650. doi:10.1007/s00535-016-1216-y
  • Vogel A, Cervantes A, Chau I, et al. Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018;29:iv238–iv255. doi:10.1093/annonc/mdy308
  • Tomczak K, Czerwińska P, Wiznerowicz M. The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge. Contemp Oncol Pozn. 2015;1A:68–77. doi:10.5114/wo.2014.47136
  • Li Y, Zhang Y, Zhang S, et al. circRNA circARNT2 Suppressed the Sensitivity of Hepatocellular Carcinoma Cells to Cisplatin by Targeting the miR-155-5p/PDK1 Axis. Mol Ther - Nucleic Acids. 2021;23:244–254. doi:10.1016/j.omtn.2020.08.037
  • Liu W, Yao Y, Shi L, Tang G, Wu L. A novel lncRNA LOLA1 may predict malignant progression and promote migration, invasion, and EMT of oral leukoplakia via the AKT/GSK‐3β pathway. J Cell Biochem. 2021;122(10):1302–1312. doi:10.1002/jcb.29951
  • Kumar L, Futschik ME. Mfuzz: a software package for soft clustering of microarray data. Bioinformation. 2007;2(1):5–7. doi:10.6026/97320630002005
  • McCarthy DJ, Chen Y, Smyth GK. Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation. Nucleic Acids Res. 2012;40(10):4288–4297. doi:10.1093/nar/gks042
  • Dong Z, Yang L, Lu J, et al. Downregulation of LINC00886 facilitates epithelial–mesenchymal transition through SIRT7/ELF3/miR-144 pathway in esophageal squamous cell carcinoma. Clin Exp Metastasis. 2022;39(4):661–677. doi:10.1007/s10585-022-10171-w
  • He G, Karin M. NF-κB and STAT3 – key players in liver inflammation and cancer. Cell Res. 2011;21(1):159–168. doi:10.1038/cr.2010.183
  • Li Y, Chen L, Zhang B, Ohno Y, Hu H. miR-409-3p inhibits the proliferation and migration of human ovarian cancer cells by targeting Rab10. Cell Mol Biol. 2020;66(7):197–201. doi:10.14715/cmb/2020.66.7.30
  • Guo R, Zou B, Liang Y, et al. LncRNA RCAT1 promotes tumor progression and metastasis via miR-214-5p/E2F2 axis in renal cell carcinoma. Cell Death Dis. 2021;12(7):689. doi:10.1038/s41419-021-03955-7
  • Li C, Yang J, Liu C, Wang X, Zhang L. Long non-coding RNAs in hepatocellular carcinoma: ordering of the complicated lncRNA regulatory network and novel strategies for HCC clinical diagnosis and treatment. Pharmacol Res. 2020;158:104848. doi:10.1016/j.phrs.2020.104848
  • Lan L, Cao H, Chi W, et al. Aberrant DNA hypermethylation-silenced LINC00886 gene accelerates malignant progression of laryngeal carcinoma. Pathol Res Pract. 2020;216(4):152877. doi:10.1016/j.prp.2020.152877
  • Mosallaei M, Ehtesham N, Rahimirad S, Saghi M, Vatandoost N, Khosravi S. PBMCs: a new source of diagnostic and prognostic biomarkers. Arch Physiol Biochem. 2022;128(4):1081–1087. doi:10.1080/13813455.2020.1752257
  • Čelešnik H, Potočnik U. Peripheral Blood Transcriptome in Breast Cancer Patients as a Source of Less Invasive Immune Biomarkers for Personalized Medicine, and Implications for Triple Negative Breast Cancer. Cancers. 2022;14(3):591. doi:10.3390/cancers14030591
  • Li H, Mao Y, Xiong Y, et al. A Comprehensive Proteome Analysis of Peripheral Blood Mononuclear Cells (PBMCs) to Identify Candidate Biomarkers of Pancreatic Cancer. Cancer Genomics - Proteomics. 2019;16(1):81–89. doi:10.21873/cgp.20114
  • Twine NC, Stover JA, Marshall B, et al. Disease-associated Expression Profiles in Peripheral Blood Mononuclear Cells from Patients with Advanced Renal Cell Carcinoma. Cancer Res. 2003;63(18):6069–6075.
  • Kunadirek P, Pinjaroen N, Nookaew I, Tangkijvanich P, Chuaypen N. Transcriptomic Analyses Reveal Long Non-Coding RNA in Peripheral Blood Mononuclear Cells as a Novel Biomarker for Diagnosis and Prognosis of Hepatocellular Carcinoma. Int J Mol Sci. 2022;23(14):7882. doi:10.3390/ijms23147882
  • Sun Q, Hao Q, Prasanth KV. Nuclear Long Noncoding RNAs: key Regulators of Gene Expression. Genomics Proteomics Bioinformatics. 2018;34(2):142–157. doi:10.1016/j.tig.2017.11.005
  • Dykes IM, Emanueli C. Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA. Genomics Proteomics Bioinformatics. 2017;15(3):177–186. doi:10.1016/j.gpb.2016.12.005
  • Pang J, Li Z, Wang G, Li N, Gao Y, Wang S. miR‐214‐5p targets KLF5 and suppresses proliferation of human hepatocellular carcinoma cells. J Cell Biochem. 2019;120(2):1850–1859. doi:10.1002/jcb.27498
  • Zhang CS, Lin Y, Sun FB, Gao J, Han B, Li SJ. miR-409 down-regulates Jak-Stat pathway to inhibit progression of liver cancer. Eur Rev Med Pharmacol Sci. 2019;23(1):146–154. doi:10.26355/eurrev_201901_16758
  • Wang W, Jia WD, Hu B, Pan YY. RAB10 overexpression promotes tumor growth and indicates poor prognosis of hepatocellular carcinoma. Oncotarget. 2017;8(16):26434–26447. doi:10.18632/oncotarget.15507
  • Zeng Z, Cao Z, Tang Y. Increased E2F2 predicts poor prognosis in patients with HCC based on TCGA data. BMC Cancer. 2020;20(1):1037. doi:10.1186/s12885-020-07529-2
  • Fan Y, Mao R, Yang J. NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer. Protein Cell. 2013;4(3):176–185. doi:10.1007/s13238-013-2084-3
  • Karin M. Nuclear factor-κB in cancer development and progression. Nature. 2006;441(7092):431–436. doi:10.1038/nature04870
  • Luedde T, Schwabe RF. NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol. 2011;8(2):108–118. doi:10.1038/nrgastro.2010.213
  • Wang D, Lou J, Ouyang C, et al. Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane. Proc Natl Acad Sci. 2010;107(31):13806–13811. doi:10.1073/pnas.1009428107
  • Wang S, Wang L, Wu C, Sun S. E2F2 directly regulates the STAT1 and PI3K/AKT/NF-κB pathways to exacerbate the inflammatory phenotype in rheumatoid arthritis synovial fibroblasts and mouse embryonic fibroblasts. Arthritis Res Ther. 2018;20(1):225. doi:10.1186/s13075-018-1713-x