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ORIGINAL RESEARCH

TRIM55 Promotes Proliferation of Hepatocellular Carcinoma Through Stabilizing TRIP6 to Activate Wnt/β-Catenin Signaling

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Pages 1281-1293 | Received 20 Apr 2023, Accepted 19 Jul 2023, Published online: 03 Aug 2023

References

  • Llovet JM, Kelley RK, Villanueva A, et al. Hepatocellular carcinoma. Nat Rev Dis Primers. 2021;7(1):6. doi:10.1038/s41572-020-00240-3
  • Yang JD, Hainaut P, Gores GJ, Amadou A, Plymoth A, Roberts LR. A global view of hepatocellular carcinoma: trends, risk, prevention and management. Nat Rev Gastroenterol Hepatol. 2019;16(10):589–604. doi:10.1038/s41575-019-0186-y
  • World Health Organization. Projections of mortality and causes of death, 2016 to 2060. Available from: http://www.who.int/healthinfo/global_burden_disease/projections/en/. Accessed July 20, 2023.
  • Zhou H, Song T. Conversion therapy and maintenance therapy for primary hepatocellular carcinoma. Biosci Trends. 2021;15(3):155–160. doi:10.5582/bst.2021.01091
  • Villanueva A. Hepatocellular Carcinoma. N Engl J Med. 2019;380(15):1450–1462. doi:10.1056/NEJMra1713263
  • Wu J, Yang S, Xu K, et al. Patterns and trends of liver cancer incidence rates in Eastern and SouthEastern Asian Countries (1983–2007) and Predictions to 2030. Gastroenterology. 2018;154(6):1719–1728 e1715. doi:10.1053/j.gastro.2018.01.033
  • Perera S, Mankoo B, Gautel M. Developmental regulation of MURF E3 ubiquitin ligases in skeletal muscle. J Muscle Res Cell Motil. 2012;33(2):107–122. doi:10.1007/s10974-012-9288-7
  • Perera S, Holt MR, Mankoo BS, Gautel M. Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover. Dev Biol. 2011;351(1):46–61. doi:10.1016/j.ydbio.2010.12.024
  • Hu MM, Shu HB. Multifaceted roles of TRIM38 in innate immune and inflammatory responses. Cell Mol Immunol. 2017;14(4):331–338. doi:10.1038/cmi.2016.66
  • Huang N, Sun X, Li P, et al. TRIM family contribute to tumorigenesis, cancer development, and drug resistance. Exp Hematol Oncol. 2022;11(1):75. doi:10.1186/s40164-022-00322-w
  • Hatakeyama S. trim family proteins: roles in autophagy, immunity, and carcinogenesis. Trends Biochem Sci. 2017;42(4):297–311. doi:10.1016/j.tibs.2017.01.002
  • Li X, Huang L, Gao W. Overexpression of Tripartite Motif Containing 55 (TRIM55) inhibits migration and invasion of Hepatocellular Carcinoma (HCC) cells via epithelial-mesenchymal transition and Matrix Metalloproteinase-2 (MMP2). Med Sci Monit. 2019;25:771–777. doi:10.12659/MSM.910984
  • Cockram PE, Kist M, Prakash S, Chen SH, Wertz IE, Vucic D. Ubiquitination in the regulation of inflammatory cell death and cancer. Cell Death Differ. 2021;28(2):591–605. doi:10.1038/s41418-020-00708-5
  • Li Q, Zhang W. Progress in anticancer drug development targeting ubiquitination-related factors. Int J Mol Sci. 2022;23(23):15104.
  • Yang K, Xiao W. Functions and mechanisms of the Ubc13-UEV complex and lysine 63-linked polyubiquitination in plants. J Exp Bot. 2022;73(16):5372–5387. doi:10.1093/jxb/erac239
  • Liu F, Liao Z, Qin L, et al. Targeting VPS72 inhibits ACTL6A/MYC axis activity in hepatocellular carcinoma progression. Hepatology. 2023. doi:10.1097/HEP.0000000000000268
  • Liao Z, Chen L, Zhang X, et al. PTPRepsilon acts as a metastatic promoter in hepatocellular carcinoma by facilitating recruitment of SMAD3 to TGF-beta receptor 1. Hepatology. 2020;72(3):997–1012. doi:10.1002/hep.31104
  • Zhu H, Zhang H, Pei Y, et al. Long non-coding RNA CCDC183-AS1 acts AS a miR-589-5p sponge to promote the progression of hepatocellular carcinoma through regulating SKP1 expression. J Exp Clin Cancer Res. 2021;40(1):57. doi:10.1186/s13046-021-01861-6
  • Song J, Liu Y, Liu F, et al. The 14-3-3 sigma protein promotes HCC anoikis resistance by inhibiting EGFR degradation and thereby activating the EGFR-dependent ERK1/2 signaling pathway. Theranostics. 2021;11(3):996–1015. doi:10.7150/thno.51646
  • Liu X, Su K, Sun X, et al. Sec62 promotes stemness and chemoresistance of human colorectal cancer through activating Wnt/beta-catenin pathway. J Exp Clin Cancer Res. 2021;40(1):132. doi:10.1186/s13046-021-01934-6
  • Hu C, Xin Z, Sun X, et al. Activation of ACLY by SEC63 deploys metabolic reprogramming to facilitate hepatocellular carcinoma metastasis upon endoplasmic reticulum stress. J Exp Clin Cancer Res. 2023;42(1):108. doi:10.1186/s13046-023-02656-7
  • Wang J, Peng R, Zhang Z, Zhang Y, Dai Y, Sun Y. Identification and validation of key genes in hepatocellular carcinoma by bioinformatics analysis. Biomed Res Int. 2021;2021:6662114. doi:10.1155/2021/6662114
  • Zhou H, Jiang L, Wang G, Su L, Hou L, Xue X. Identification of MCM4 as a prognostic marker of hepatocellular carcinoma. Biomed Res Int. 2021;2021:7479326. doi:10.1155/2021/7479326
  • Rao B, Li J, Ren T, et al. RPL19 is a prognostic biomarker and promotes tumor progression in hepatocellular carcinoma. Front Cell Dev Biol. 2021;9:686547. doi:10.3389/fcell.2021.686547
  • Hou Y, Wang Z, Huang S, et al. SKA3 Promotes tumor growth by regulating CDK2/P53 phosphorylation in hepatocellular carcinoma. Cell Death Dis. 2019;10(12):929. doi:10.1038/s41419-019-2163-3
  • Gou H, Liang JQ, Zhang L, et al. TTPAL promotes colorectal tumorigenesis by stabilizing trip6 to activate wnt/beta-catenin signaling. Cancer Res. 2019;79(13):3332–3346. doi:10.1158/0008-5472.CAN-18-2986
  • van WijkSJ, Fulda S, Dikic I, Heilemann M, van Wijk SJ. Visualizing ubiquitination in mammalian cells. EMBO Rep. 2019;20(2). doi:10.15252/embr.201846520
  • Zhu L, Qin C, Li T, et al. The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein. Cell Death Differ. 2020;27(6):1819–1831. doi:10.1038/s41418-019-0464-9
  • Hu X, Tang Z, Ma S, Yu Y, Chen X, Zang G. Tripartite motif-containing protein 7 regulates hepatocellular carcinoma cell proliferation via the DUSP6/p38 pathway. Biochem Biophys Res Commun. 2019;511(4):889–895. doi:10.1016/j.bbrc.2019.02.001
  • Xu M, Hu J, Zhou B, Zhong Y, Lin N, Xu R. TRIM29 prevents hepatocellular carcinoma progression by inhibiting Wnt/beta-catenin signaling pathway. Acta Biochim Biophys Sin. 2019;51(1):68–77. doi:10.1093/abbs/gmy151
  • Du H, Xu Q, Xiao S, et al. MicroRNA-424-5p acts as a potential biomarker and inhibits proliferation and invasion in hepatocellular carcinoma by targeting TRIM29. Life Sci. 2019;224:1–11. doi:10.1016/j.lfs.2019.03.028
  • Huang G, Liang M, Liu H, et al. CircRNA hsa_circRNA_104348 promotes hepatocellular carcinoma progression through modulating miR-187-3p/RTKN2 axis and activating Wnt/beta-catenin pathway. Cell Death Dis. 2020;11(12):1065. doi:10.1038/s41419-020-03276-1
  • Gur’ianova OA, Sablina AA, Chumakov PM, Frolova EI. Down-regulation of TRIP6 expression induces actin cytoskeleton rearrangements in human carcinoma cell lines. Mol Biol. 2005;39(5):905–909.
  • Zhao W, Dai Y, Dai T, et al. TRIP6 promotes cell proliferation in hepatocellular carcinoma via suppression of FOXO3a. Biochem Biophys Res Commun. 2017;494(3–4):594–601. doi:10.1016/j.bbrc.2017.10.117
  • Lin VT, Lin FT. TRIP6: an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity. Cell Signal. 2011;23(11):1691–1697. doi:10.1016/j.cellsig.2011.06.004
  • Lu K, Pan Y, Huang Z, Liang H, Ding ZY, Zhang B. TRIM proteins in hepatocellular carcinoma. J Biomed Sci. 2022;29(1):69. doi:10.1186/s12929-022-00854-7
  • Zhan W, Zhang S. TRIM proteins in lung cancer: mechanisms, biomarkers and therapeutic targets. Life Sci. 2021;268:118985. doi:10.1016/j.lfs.2020.118985
  • Chen SY, Zhang HP, Li J, et al. Tripartite motif-containing 27 attenuates liver ischemia/reperfusion injury by suppressing Transforming Growth Factor beta-Activated Kinase 1 (TAK1) by TAK1 binding protein 2/3 degradation. Hepatology. 2021;73(2):738–758. doi:10.1002/hep.31295
  • Dai CY, Lin CY, Tsai PC, et al. Impact of tumor size on the prognosis of hepatocellular carcinoma in patients who underwent liver resection. J Chin Med Assoc. 2018;81(2):155–163. doi:10.1016/j.jcma.2017.06.018