Cardioprotective Effect of Gossypin Against Myocardial Ischemic/Reperfusion in Rats via Alteration of Oxidative Stress, Inflammation and Gut Microbiota

References

• Panda S, Kar A, Biswas S. Preventive effect of Agnucastoside C against isoproterenol-induced myocardial injury. Sci Rep. 2017;7(1). doi:10.1038/s41598-017-16075-0
   Web of Science ®Google Scholar
• Fan Y. Cardioprotective effect of rhapontigenin in isoproterenol-induced myocardial infarction in a rat model. Pharmacology. 2019;103(5–6):291–302. doi:10.1159/000496800
   PubMed Web of Science ®Google Scholar
• Roth GA, Mensah GA, Johnson CO, et al. Global burden of cardiovascular diseases and risk factors, 1990–2019: update From the GBD 2019 Study. J Am Coll Cardiol. 2020;76(25):2982–3021. doi:10.1016/j.jacc.2020.11.010
   PubMed Web of Science ®Google Scholar
• Adedapo AA, Adeoye BO, Oyagbemi AA, Omobowale TO, Yakubu MA. Cardioprotective effects of the ethanol leaf extract of andrographis paniculata in isoprotereno l-induced myocardial infarction in rats. FASEB J. 2017;31(1Supplement 1). Available from: http://www.fasebj.org/content/31/1_Supplement/1070.12.abstract?sid=63efa7fd-3bba-4fc9-9138-51c75457d9b9%0Ahttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed18&NEWS=N&AN=616904111. Accessed January 12, 2022.
   Google Scholar
• Sreeniwas Kumar A, Sinha N. Cardiovascular disease in India: a 360 degree overview. Med J Armed Forces India. 2020;76(1):1–3. doi:10.1016/j.mjafi.2019.12.005
   PubMedGoogle Scholar
• Ganapathy R, Ramachandran A, Shivalingaiah SB, et al. Cardioprotective potential of polyphenols rich Thraatchathi Chooranam against isoproterenol induced myocardial necrosis in experimental rats. BMC Complement Med Ther. 2020;20(1). doi:10.1186/s12906-020-03124-x
   PubMedGoogle Scholar
• Zhu L, Wei T, Chang X, et al. Effects of salidroside on myocardial injury in vivo in vitro via regulation of Nox/NF-κB/AP1 pathway. Inflammation. 2015;38(4):1589–1598. doi:10.1007/s10753-015-0134-0
   PubMed Web of Science ®Google Scholar
• Raja S, Ramya I, Ravindranadh K. A review on protective role of phytoconstituents against isoproterenol induced myocardial necrosis. Int J Pharmacogn Phytochem Res. 2016;8(5):848–864.
   Google Scholar
• Murugesan S, Pandiyan A, Saravanakumar L, Moodley K, Mackraj I. Protective role of wild garlic on isoproterenol-induced myocardial necrosis in Wistar rats. J Ethnopharmacol. 2019;237:108–115. doi:10.1016/j.jep.2019.03.049
   PubMed Web of Science ®Google Scholar
• Krishna RG, Sundara rajan R. Cardioprotective and antioxidant effects of Bougainvillea glabra against isoproterenol induced myocardial necrosis in albino rats. Int J Phytomedicine. 2018;10(1):45. doi:10.5138/09750185.2200
   Google Scholar
• Singh N, Kumar R. Effect of nicorandil and amlodipine on bio-chemical parameters during isoproterenol induced myocardial necrosis in rats. Indian J Clin Biochem. 2003;18(1):99–102. doi:10.1007/BF02867674
   PubMedGoogle Scholar
• Raja S, Ramya I. Cardioprotective potential of methanol extract of Polygonum glabrum on isoproterenol induced myocardial necrosis in rats. Int J Phytomedicine. 2017;9(3):518. doi:10.5138/09750185.2125
   Google Scholar
• Wang Z, Zhang F, Liu W, Sheng N, Sun H, Zhang J. Impaired tricarboxylic acid cycle flux and mitochondrial aerobic respiration during isoproterenol induced myocardial ischemia is rescued by bilobalide. J Pharm Anal. 2021. doi:10.1016/j.jpha.2020.08.008
   Web of Science ®Google Scholar
• Wang C, Peng D, Liu Y, Yu Z, Guo P, Wei J. Agarwood alcohol extract ameliorates isoproterenol-induced myocardial ischemia by inhibiting oxidation and apoptosis. Cardiol Res Pract. 2020;2020:1–10. doi:10.1155/2020/3640815
   Web of Science ®Google Scholar
• Fan S, Zhang J, Xiao Q, et al. Cardioprotective effect of the polysaccharide from Ophiopogon japonicus on isoproterenol-induced myocardial ischemia in rats. Int J Biol Macromol. 2020;147:233–240. doi:10.1016/j.ijbiomac.2020.01.068
   PubMed Web of Science ®Google Scholar
• Huang K, Liu Y, Tang H, et al. Glabridin prevents doxorubicin-induced cardiotoxicity through gut microbiota modulation and colonic macrophage polarization in mice. Front Pharmacol. 2019;10(February). doi:10.3389/fphar.2019.00107
   Web of Science ®Google Scholar
• Huang Z, Gan J, Jia L, et al. An orally administrated nucleotide-delivery vehicle targeting colonic macrophages for the treatment of inflammatory bowel disease. Biomaterials. 2015;48:26–36. doi:10.1016/j.biomaterials.2015.01.013
   PubMed Web of Science ®Google Scholar
• Magne F, Gotteland M, Gauthier L, et al. The Firmicutes/Bacteroidetes ratio: a relevant marker of gut dysbiosis in obese patients? Nutrients. 2020;12(5):1474. doi:10.3390/nu12051474
   PubMed Web of Science ®Google Scholar
• Jandhyala SM, Talukdar R, Subramanyam C, Vuyyuru H, Sasikala M, Reddy DN. Role of the normal gut microbiota. World J Gastroenterol. 2015;21(29):8836–8847. doi:10.3748/wjg.v21.i29.8787
   PubMed Web of Science ®Google Scholar
• Naqvi S, Asar TO, Kumar V, et al. A cross-talk between gut microbiome, salt and hypertension. Biomed Pharmacother. 2021;134:111156. doi:10.1016/j.biopha.2020.111156
   PubMed Web of Science ®Google Scholar
• Viswanadha VP, Dhivya V, Somasundaram B, et al. The role of mitochondria in piperine mediated cardioprotection in isoproterenol induced myocardial ischemia. Curr Pharm Des. 2020;27(26):2975–2989. doi:10.2174/1381612826666200909125750
   Web of Science ®Google Scholar
• Verma VK, Arya D, Bhatia J. Morin ameliorates isoproterenol induced myocardial necrosis in rats. Proc Annu Meet Jpn Pharmacol Soc. 2018;WCP2018:PO4-2-40. doi:10.1254/jpssuppl.wcp2018.0_po4-2-40
   Google Scholar
• Fathima SN, Vasudeva Murthy S. Current pharmacological status of cardioprotective plants against isoproterenol induced myocardial infarction. Asian J Pharm Clin Res. 2018;11(4):17–27. doi:10.22159/ajpcr.2018.v11i4.24158
   Google Scholar
• Ciumărnean L, Milaciu MV, Runcan O, et al. The effects of flavonoids in cardiovascular diseases. Molecules. 2020;25(18):18. doi:10.3390/molecules25184320
   Web of Science ®Google Scholar
• Bhardwaj JS, Manandhar S, Chatterjee S, et al. Protective effects of gossypin in colchicine-induced cognitive dysfunction and oxidative damage in rats. Res J Pharm Technol. 2020;13(11):5189–5196. doi:10.5958/0974-360X.2020.00907.5
   Google Scholar
• Tanyeli A, Eraslan E, Güler MC, Kurt N, Akaras N. Gossypin protects against renal ischemia-reperfusion injury in rats. Kafkas Univ Vet Fak Derg. 2020;26(1):89–96. doi:10.9775/kvfd.2019.22396
   Web of Science ®Google Scholar
• Cinar I, Yayla M, Tavaci T, et al. In vivo and in vitro cardioprotective effect of gossypin against isoproterenol-induced myocardial infarction injury. Cardiovasc Toxicol. 2021;22(1):52–62. doi:10.1007/s12012-021-09698-3
   PubMed Web of Science ®Google Scholar
• Gautam P, Flora SJS. Oral supplementation of gossypin during lead exposure protects alteration in heme synthesis pathway and brain oxidative stress in rats. Nutrition. 2010;26(5):563–570. doi:10.1016/j.nut.2009.06.008
   PubMed Web of Science ®Google Scholar
• Venkatesan T, Sorimuthu Pillai S. Antidiabetic activity of gossypin, a pentahydroxyflavone glucoside, in streptozotocin-induced experimental diabetes in rats. J Diabetes. 2012;4(1):41–46. doi:10.1111/j.1753-0407.2011.00145.x
   PubMed Web of Science ®Google Scholar
• Kardeş S, Karakuş E, Gelen V, et al. Neuroprotective effect of gossypin on glutamate-induced excitotoxic neuronal death in SH-SY5Y cell line. Toxicol Lett. 2016;258:S286. doi:10.1016/j.toxlet.2016.06.1997
   Web of Science ®Google Scholar
• Ji L, Tian Z, Liu Y, Liu M. Protective effect of casticin in myocardial ischemia/reperfusion injury in rats via attenuation of oxidative stress and inflammation. Arch Med Sci. 2021. doi:10.5114/aoms/127588
   Google Scholar
• Raish M. Momordica charantia polysaccharides ameliorate oxidative stress, hyperlipidemia, inflammation, and apoptosis during myocardial infarction by inhibiting the NF-κB signaling pathway. Int J Biol Macromol. 2017;97:544–551. doi:10.1016/j.ijbiomac.2017.01.074
   PubMed Web of Science ®Google Scholar
• Fathiazad F, Tamarzadeh N, Alsos D, Garjani A, Vaez H. The effect of astragaloside IV on isoproterenol-induced myocardial infarction in rats. Pharm Sci. 2019;25(2):100–110. doi:10.15171/PS.2019.16
   Web of Science ®Google Scholar
• Goyal SN, Sharma C, Mahajan UB, et al. Protective effects of cardamom in isoproterenol-induced myocardial infarction in rats. Int J Mol Sci. 2015;16(11):27457–27469. doi:10.3390/ijms161126040
   PubMed Web of Science ®Google Scholar
• Govindasami S, Uddandrao VVS, Raveendran N, Sasikumar V. Therapeutic potential of biochanin-a against isoproterenol-induced myocardial infarction in rats. Cardiovasc Hematol Agents Med Chem. 2020;18(1):31–36. doi:10.2174/1871525718666200206114304
   PubMedGoogle Scholar
• Ouyang B, Li Z, Ji X, Huang J, Zhang H, Jiang C. The protective role of lutein on isoproterenol-induced cardiac failure rat model through improving cardiac morphology, antioxidant status via positively regulating Nrf2/HO-1 signalling pathway. Pharm Biol. 2019;57(1):529–535. doi:10.1080/13880209.2019.1649436
   PubMed Web of Science ®Google Scholar
• Li H, Song F, Duan LR, et al. Paeonol and danshensu combination attenuates apoptosis in myocardial infarcted rats by inhibiting oxidative stress: roles of Nrf2/HO-1 and PI3K/Akt pathway. Sci Rep. 2016;6. doi:10.1038/srep23693
   Web of Science ®Google Scholar
• Huang H, Geng Q, Yao H, et al. Protective effect of scutellarin on myocardial infarction induced by isoprenaline in rats. Iran J Basic Med Sci. 2018;21(3):267–276. doi:10.22038/ijbms.2018.26110.6415
   PubMed Web of Science ®Google Scholar
• Mundugaru R, Udaykumar P, Senthilkumar S, Bhat S. Cardioprotective activity of fruit of Garcinia pedunculata on isoprenaline-induced myocardial infarction in rat. Bangladesh J Pharmacol. 2016;11(1):231–235. doi:10.3329/bjp.v11i1.24941
   Web of Science ®Google Scholar
• Abdelhalim AT, Nur NM, Mansour S, Ibrahim A. Cardioprotective effect of vitamin e against myocardial infarction induced by isoprenaline in albino rats. Asian J Pharm Clin Res. 2018;11(6):273–276. doi:10.22159/ajpcr.2018.v11i6.24999
   Google Scholar
• Shen Z, Geng Q, Huang H, et al. Antioxidative and cardioprotective effects of schisandra chinensis bee pollen extract on isoprenaline-induced myocardial infarction in rats. Molecules. 2019;24(6):1090. doi:10.3390/molecules24061090
   PubMed Web of Science ®Google Scholar
• Zhang X, Li X, Wang C, et al. Ameliorative effect of ferruginol on isoprenaline hydrochloride-induced myocardial infarction in rats. Environ Toxicol. 2021;36(2):249–256. doi:10.1002/tox.23030
   PubMed Web of Science ®Google Scholar
• Zarkasi KA, Zainalabidin S, Jen-Kit T, Hakimi NH, Ramli NZ, Jubri Z. Tocotrienol-rich fraction modulates cardiac metabolic profile changes in isoprenaline-induced myocardial infarction rats. Sains Malays. 2020;49(2):357–373. doi:10.17576/jsm-2020-4902-14
   Web of Science ®Google Scholar
• Zaafan MA, Abdelhamid AM. The cardioprotective effect of astaxanthin against isoprenaline-induced myocardial injury in rats: involvement of TLR4/NF-κB signaling pathway. Eur Rev Med Pharmacol Sci. 2021;25(11):4099–4105. doi:10.26355/eurrev_202106_26052
   PubMed Web of Science ®Google Scholar
• Tawfik MK, Ghattas MH, Abo-Elmatty DM, Abdel-Aziz NA. Atorvastatin restores the balance between pro-inflammatory and anti-inflammatory mediators in rats with acute myocardial infarction. Eur Rev Med Pharmacol Sci. 2010;14(6):499–506.
   PubMed Web of Science ®Google Scholar
• Badavi M, Mard SA, Dianat M, Dashtbozorgi N. Crocin attenuates oxidative stress and inflammation in myocardial infarction induced by isoprenaline via PPARγ activation in diabetic rats. J Diabetes Metab Disord. 2020;19(2):1517–1525. doi:10.1007/s40200-020-00686-y
   PubMed Web of Science ®Google Scholar
• Kopustinskiene DM, Jakstas V, Savickas A, Bernatoniene J. Flavonoids as anticancer agents. Nutrients. 2020;12(2):457. doi:10.3390/nu12020457
   PubMed Web of Science ®Google Scholar
• Reinhardt D, Sigusch HH, Henße J, Tyagi SC, Körfer R, Figulla HR. Cardiac remodelling in end stage heart failure: upregulation of matrix metalloproteinase (MMP) irrespective of the underlying disease, and evidence for a direct inhibitory effect of ACE inhibitors on MMP. Heart. 2002;88(5):525–530. doi:10.1136/heart.88.5.525
   PubMed Web of Science ®Google Scholar
• Periasamy S, Mo FE, Chen SY, Chang CC, Liu MY. Sesamol attenuates isoproterenol-induced acute myocardial infarction via inhibition of matrix metalloproteinase-2 and −9 expression in rats. Cell Physiol Biochem. 2011;27(3–4):273–280. doi:10.1159/000327953
   PubMedGoogle Scholar
• Boarescu P-M, Chirilǎ I, Bulboacǎ AE, et al. Effects of curcumin nanoparticles in isoproterenol-induced myocardial infarction. Oxid Med Cell Longev. 2019;2019:1–13. doi:10.1016/j.mjafi.2019.12.005
   Web of Science ®Google Scholar
• Kho ZY, Lal SK. The human gut microbiome - a potential controller of wellness and disease. Front Microbiol. 2018;9(AUG). doi:10.3389/fmicb.2018.01835
   PubMed Web of Science ®Google Scholar
• Brahe LK, Astrup A, Larsen LH. Is butyrate the link between diet, intestinal microbiota and obesity-related metabolic diseases? Obes Rev. 2013;14(12):950–959. doi:10.1111/obr.12068
   PubMed Web of Science ®Google Scholar
• Luissint AC, Parkos CA, Nusrat A. Inflammation and the intestinal barrier: leukocyte–epithelial cell interactions, cell junction remodeling, and mucosal repair. Gastroenterology. 2016;151(4):616–632. doi:10.1053/j.gastro.2016.07.008
   PubMed Web of Science ®Google Scholar