High Level of Serum Uric Acid induced Monocyte Inflammation is Related to Coronary Calcium Deposition in the Middle-Aged and Elder Population of China: A five-year Prospective Cohort Study

References

• Culleton BF, Larson MG, Kannel WB, Levy D. Serum uric acid and risk for cardiovascular disease and death: the Framingham Heart Study. Ann Intern Med. 1999;131(1):7–13.
   PubMed Web of Science ®Google Scholar
• Fang J, Alderman MH. Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey. JAMA. 2000;283(18):2404–2410.
   PubMed Web of Science ®Google Scholar
• Wu AH, Gladden JD, Ahmed M, Ahmed A, Filippatos G. Relation of serum uric acid to cardiovascular disease. Int J Cardiol. 2016;213:4–7.
   PubMed Web of Science ®Google Scholar
• Ruparelia N, Chai JT, Fisher EA, Choudhury RP. Inflammatory processes in cardiovascular disease: a route to targeted therapies. Nat Rev Cardiol. 2017;14(5):314.
   PubMed Web of Science ®Google Scholar
• Kawamoto R, Tomita H, Oka Y, Ohtsuka N. Relationship between serum uric acid concentration, metabolic syndrome and carotid atherosclerosis. Intern Med. 2006;45(9):605–614.
   PubMed Web of Science ®Google Scholar
• Rodrigues TC, Maahs DM, Johnson RJ, et al. Serum uric acid predicts progression of subclinical coronary atherosclerosis in individuals without renal disease. Diabetes Care. 2010;33(11):2471–2473.
   PubMed Web of Science ®Google Scholar
• Takayama S, Kawamoto R, Kusunoki T, Abe M, Onji M. Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome. Cardiovasc Diabetol. 2012;11:2.
   PubMed Web of Science ®Google Scholar
• Jayachandran M, Qu S. Harnessing hyperuricemia to atherosclerosis and understanding its mechanistic dependence. Med Res Rev. 2021;41(1):616–629.
   PubMed Web of Science ®Google Scholar
• Kimura Y, Yanagida T, Onda A, Tsukui D, Hosoyamada M, Kono H. Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation. Arterioscler Thromb Vasc Biol. 2020;40(3):570–582.
   PubMed Web of Science ®Google Scholar
• Puddu P, Puddu GM, Cravero E, Vizioli L, Muscari A. Relationships among hyperuricemia, endothelial dysfunction and cardiovascular disease: molecular mechanisms and clinical implications. J Cardiol. 2012;59(3):235–242.
   PubMed Web of Science ®Google Scholar
• Rao GN, Corson MA, Berk BC. Uric acid stimulates vascular smooth muscle cell proliferation by increasing platelet-derived growth factor A-chain expression. J Biol Chem. 1991;266(13):8604–8608.
   PubMed Web of Science ®Google Scholar
• Rock KL, Kataoka H, Lai JJ. Uric acid as a danger signal in gout and its comorbidities. Nat Rev Rheumatol. 2013;9(1):13–23.
   PubMed Web of Science ®Google Scholar
• Zimmer S, Grebe A, Latz E. Danger signaling in atherosclerosis. Circ Res. 2015;116(2):323–340.
   PubMed Web of Science ®Google Scholar
• Flores-Gomez D, Bekkering S, Netea MG, Riksen NP. Trained Immunity in Atherosclerotic Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2021;41(1):62–69.
   PubMed Web of Science ®Google Scholar
• Lee S, Bartlett B, Dwivedi G. Adaptive Immune Responses in Human Atherosclerosis. Int J Mol Sci. 2020;21:23.
   Web of Science ®Google Scholar
• Hou ZH, Lu B, Gao Y, et al. Prognostic value of coronary CT angiography and calcium score for major adverse cardiac events in outpatients. JACC Cardiovasc Imaging. 2012;5(10):990–999.
   PubMed Web of Science ®Google Scholar
• Chaikriangkrai K, Velankar P, Schutt R, et al. Additive prognostic value of coronary artery calcium score over coronary computed tomographic angiography stenosis assessment in symptomatic patients without known coronary artery disease. Am J Cardiol. 2015;115(6):738–744.
   PubMed Web of Science ®Google Scholar
• Dzaye O, Dudum R, Mirbolouk M, et al. Validation of the Coronary Artery Calcium Data and Reporting System (CAC-DRS): dual importance of CAC score and CAC distribution from the Coronary Artery Calcium (CAC) consortium. J Cardiovasc Comput Tomogr. 2020;14(1):12–17.
   PubMed Web of Science ®Google Scholar
• Polonsky TS, McClelland RL, Jorgensen NW, et al. Coronary artery calcium score and risk classification for coronary heart disease prediction. JAMA. 2010;303(16):1610–1616.
   PubMed Web of Science ®Google Scholar
• Qazi AH, Zallaghi F, Torres-Acosta N, Thompson RC, O’Keefe JH. Computed Tomography for Coronary Artery Calcification Scoring: mammogram for the Heart. Prog Cardiovasc Dis. 2016;58(5):529–536.
   PubMed Web of Science ®Google Scholar
• Wexler L, Brundage B, Crouse J, et al. Coronary artery calcification: pathophysiology, epidemiology, imaging methods, and clinical implications. A statement for health professionals from the American Heart Association. Writing Group. Circulation. 1996;94(5):1175–1192.
   PubMed Web of Science ®Google Scholar
• Kamimura D, Cain-Shields LR, Clark D, et al. Physical Activity, Inflammation, Coronary Artery Calcification, and Incident Coronary Heart Disease in African Americans: insights From the Jackson Heart Study. Mayo Clin Proc. 2021;96(4):901–911.
   PubMed Web of Science ®Google Scholar
• Ong KL, McClelland RL, Allison MA, et al. Lipoprotein (a) and coronary artery calcification: prospective study assessing interactions with other risk factors. Metabolism. 2021;116:154706.
   PubMed Web of Science ®Google Scholar
• Lee TS, Lu TM, Chen CH, Guo BC, Hsu CP. Hyperuricemia induces endothelial dysfunction and accelerates atherosclerosis by disturbing the asymmetric dimethylarginine/dimethylarginine dimethylaminotransferase 2 pathway. Redox Biol. 2021;46:102108.
   PubMed Web of Science ®Google Scholar
• Mannarino MR, Pirro M, Gigante B, et al. Association Between Uric Acid, Carotid Intima-Media Thickness, and Cardiovascular Events: prospective Results From the IMPROVE Study. J Am Heart Assoc. 2021;10(11):e020419.
   PubMed Web of Science ®Google Scholar
• Drivelegka P, Forsblad-d’Elia H, Angeras O, et al. Association between serum level of urate and subclinical atherosclerosis: results from the SCAPIS Pilot. Arthritis Res Ther. 2020;22(1):37.
   PubMed Web of Science ®Google Scholar
• Geng S, Chen K, Yuan R, et al. The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis. Nat Commun. 2016;7:13436.
   PubMed Web of Science ®Google Scholar
• Wesselink E, van Baar H, van Zutphen M, et al. Inflammation Is a Mediating Factor in the Association between Lifestyle and Fatigue in Colorectal Cancer Patients. Cancers. 2020;12:12.
   Web of Science ®Google Scholar
• Michiels C, Puigdevall L, Cochez P, et al. A Targetable, Noncanonical Signal Transducer and Activator of Transcription 3 Activation Induced by the Y-Less Region of IL-22 Receptor Orchestrates Imiquimod-Induced Psoriasis-Like Dermatitis in Mice. J Invest Dermatol. 2021;2:987.
   Google Scholar
• Tercan H, Riksen NP, Joosten LAB, Netea MG, Bekkering S. Trained Immunity: long-Term Adaptation in Innate Immune Responses. Arterioscler Thromb Vasc Biol. 2021;41(1):55–61.
   PubMed Web of Science ®Google Scholar
• Luis-Rodriguez D, Donate-Correa J, Martin-Nunez E, et al. Serum urate is related to subclinical inflammation in asymptomatic hyperuricaemia. Rheumatology. 2021;60(1):371–379.
   PubMed Web of Science ®Google Scholar
• Fragoulis GE, Soulaidopoulos S, Sfikakis PP, Dimitroulas T, DK G. Effect of Biologics on Cardiovascular Inflammation: mechanistic Insights and Risk Reduction. J Inflamm Res. 2021;14:1915–1931.
   PubMed Web of Science ®Google Scholar
• Braga TT, Davanso MR, Mendes D, et al. Sensing soluble uric acid by Naip1-Nlrp3 platform. Cell Death Dis. 2021;12(2):158.
   PubMed Web of Science ®Google Scholar
• Roman MJ, Shanker BA, Davis A, et al. Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus. N Engl J Med. 2003;349(25):2399–2406.
   PubMed Web of Science ®Google Scholar
• Baker JF, Krishnan E, Chen L, Schumacher HR. Serum uric acid and cardiovascular disease: recent developments, and where do they leave us? Am J Med. 2005;118(8):816–826.
   PubMed Web of Science ®Google Scholar
• Duewell P, Kono H, Rayner KJ, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010;464(7293):1357–1361.
   PubMed Web of Science ®Google Scholar
• Li-Yu J, Clayburne G, Sieck M, et al. Treatment of chronic gout. Can we determine when urate stores are depleted enough to prevent attacks of gout? J Rheumatol. 2001;28(3):577–580.
   PubMed Web of Science ®Google Scholar
• Han M, Kim H, Kim HJ, et al. Serum uric acid is associated with coronary artery calcification in early chronic kidney disease: a cross-sectional study. BMC Nephrol. 2021;22(1):247.
   PubMed Web of Science ®Google Scholar
• Liang L, Hou X, Bainey KR, et al. The association between hyperuricemia and coronary artery calcification development: a systematic review and meta-analysis. Clin Cardiol. 2019;42(11):1079–1086.
   PubMed Web of Science ®Google Scholar
• Kiss LZ, Bagyura Z, Csobay-Novak C, et al. Serum Uric Acid Is Independently Associated with Coronary Calcification in an Asymptomatic Population. J Cardiovasc Transl Res. 2019;12(3):204–210.
   PubMed Web of Science ®Google Scholar