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CLINICAL TRIAL REPORT

Anti-Inflammatory Effect of Ulinastatin on the Association Between Inflammatory Phenotypes in Acute Type A Aortic Dissection

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Pages 3709-3718 | Published online: 27 Jun 2022

References

  • Allaire E, Schneider F, Saucy F, et al. New insight in aetiopathogenesis of aortic diseases. Eur J Vasc Endovasc Surg. 2009;37(5):531–537. doi:10.1016/j.ejvs.2009.02.002
  • Depner M, Fuchs O, Genuneit J, et al.; PASTURE Study Group. Clinical and epidemiologic phenotypes of childhood asthma. Am J Respir Crit Care Med. 2014;189(2):129–138. doi:10.1164/rccm.201307-1198OC
  • Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA; NHLBI ARDS Network. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med. 2014;2(8):611–620. doi:10.1016/S2213-2600(14)70097-9
  • Seymour CW, Kennedy JN, Wang S, et al. Derivation, validation, and potential treatment implications of novel clinical phenotypes for sepsis. JAMA. 2019;321(20):2003–2017. doi:10.1001/jama.2019.5791
  • Takano H, Inoue K, Shimada A, Sato H, Yanagisawa R, Yoshikawa T. Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice. Lab Invest. 2009;89(7):833–839. doi:10.1038/labinvest.2009.35
  • Czerny M, Schoenhoff F, Etz C, et al. The impact of pre-operative malperfusion on outcome in acute type A aortic dissection: results from the GERAADA registry. J Am Coll Cardiol. 2015;65:2628–2635. doi:10.1016/j.jacc.2015.04.030
  • Kanai T, Ishiwata T, Kobayashi T, et al. Ulinastatin, a urinary trypsin inhibitor, for the initial treatment of patients with Kawasaki disease: a retrospective study. Circulation. 2011;124(25):2822–2828. doi:10.1161/CIRCULATIONAHA.111.028423
  • Astrup T, Nissen U. urinary trypsin inhibitor (MINGIN): transformation into a new trypsin inhibitor by acid hydrolysis or by sialidase. Nature. 1964;203:255–257. doi:10.1038/203255a0
  • He G, Li Q, Li W, et al. Effect of ulinastatin on interleukins and pulmonary function in bypass patients: a meta-analysis of randomized controlled trials. Herz. 2020;45(4):335–346. doi:10.1007/s00059-018-4732-0
  • Zhenyu H, Qiaoli Y, Guangxiang C, Maohua W. The effect of ulinastatin on postoperative course in cardiopulmonary bypass patients in Asia: a meta-analysis of randomized controlled trials. J Cardiothorac Surg. 2022;17(1):66. doi:10.1186/s13019-022-01811-z
  • Sun L, Qi R, Zhu J, Liu Y, Zheng J. Total arch replacement combined with stented elephant trunk implantation: a new “standard” therapy for type a dissection involving repair of the aortic arch? Circulation. 2011;123(9):971–978. doi:10.1161/CIRCULATIONAHA.110.015081
  • Overman DM, Jacobs JP, Prager RL, et al. Report from the society of thoracic surgeons national database workforce: clarifying the definition of operative mortality. World J Pediatr Congenit Heart Surg. 2013;4(1):10–12. doi:10.1177/2150135112461924
  • Rindskopf D, Rindskopf W. The value of latent class analysis in medical diagnosis. Stat Med. 1986;5(1):21–27. doi:10.1002/sim.4780050105
  • Schwartz G. Estimating the dimension of a model. Ann Stat. 1978;6:461–464.
  • Lo YT, Mendell NR, Rubin DB. Testing the number of components in a normal mixture. Biometrika. 2001;88(3):767–778. doi:10.1093/biomet/88.3.767
  • Augoustides JG, Szeto WY, Desai ND, et al. Classification of acute type A dissection: focus on clinical presentation and extent. Eur J Cardiothorac Surg. 2011;39(4):519–522. doi:10.1016/j.ejcts.2010.05.038
  • Dake MD, Thompson M, van Sambeek M, Vermassen F, Morales JP. DEFINE Investigators. DISSECT: a new mnemonic-based approach to the categorization of aortic dissection. Eur J Vasc Endovasc Surg. 2013;46(2):175–190. doi:10.1016/j.ejvs.2013.04.029
  • Sievers HH, Rylski B, Czerny M, et al. Aortic dissection reconsidered: type, entry site, malperfusion classification adding clarity and enabling outcome prediction. Interact Cardiovasc Thorac Surg. 2020;30(3):451–457. doi:10.1093/icvts/ivz281
  • Rimmer LJ, Moughal S, Bashir M. Immunological therapeutics in acute aortic syndrome. Asian Cardiovasc Thorac Ann. 2020;28(8):512–519. doi:10.1177/0218492320943350
  • Xu CE, Zou CW, Zhang MY, Guo L. Effects of high-dose ulinastatin on inflammatory response and pulmonary function in patients with type-A aortic dissection after cardiopulmonary bypass under deep hypothermic circulatory arrest. J Cardiothorac Vasc Anesth. 2013;27(3):479–484. doi:10.1053/j.jvca.2012.11.001
  • Nakanishi K, Takeda S, Sakamoto A, Kitamura A. Effects of ulinastatin treatment on the cardiopulmonary bypass-induced hemodynamic instability and pulmonary dysfunction. Crit Care Med. 2006;34(5):1351–1357. doi:10.1097/01.CCM.0000215110.55899.AE
  • Cao C, Yin C, Shou S, et al. Ulinastatin protects against LPS-induced acute lung injury by attenuating TLR4/NF-κB pathway activation and reducing inflammatory mediators. Shock. 2018;50(5):595–605. doi:10.1097/SHK.0000000000001104
  • Wang J, Zhou J, Bai S. Combination of glutamine and ulinastatin treatments greatly improves sepsis outcomes. J Inflamm Res. 2020;13:109–115. doi:10.2147/JIR.S234122
  • Song D, Song G, Niu Y, et al. Ulinastatin activates haem oxygenase 1 antioxidant pathway and attenuates allergic inflammation. Br J Pharmacol. 2014;171(19):4399–4412. doi:10.1111/bph.12780
  • Karnad DR, Bhadade R, Verma PK, et al. Intravenous administration of ulinastatin (human urinary trypsin inhibitor) in severe sepsis: a multicenter randomized controlled study. Intensive Care Med. 2014;40(6):830–838. doi:10.1007/s00134-014-3278-8