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ORIGINAL RESEARCH

TXNIP Participated in NLRP3-Mediated Inflammation in a Rat Model of Cervical Spondylotic Myelopathy

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Pages 4547-4559 | Published online: 09 Aug 2022

References

  • Zhou LY, Yao M, Tian ZR, et al. Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1-dependent mitochondrial fission. J Neurochem. 2020;155(2):154–176. doi:10.1111/jnc.15011.
  • McCormick JR, Sama AJ, Schiller NC, Butler AJ, Donnally CJ 3rd. Cervical spondylotic myelopathy: a guide to diagnosis and management. J Am Board Fam Med. 2020;33(2):303–313. doi:10.3122/jabfm.2020.02.190195.
  • Dhillon RS, Parker J, Syed YA, et al. Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy. Acta Neuropathol Commun. 2016;4(1):89. doi:10.1186/s40478-016-0359-7.
  • Zhou L, Yao M, Tian Z, et al. Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission. Free Radic Biol Med. 2020;152:697–714. doi:10.1016/j.freeradbiomed.2020.01.014.
  • Moon ES, Karadimas SK, Yu WR, Austin JW, Fehlings MG. Riluzole attenuates neuropathic pain and enhances functional recovery in a rodent model of cervical spondylotic myelopathy. Neurobiol Dis. 2014;62:394–406. doi:10.1016/j.nbd.2013.10.020.
  • Isobe T, Yaguchi H, Matsui K, Inoue K. [A case of cervical spondylotic amyotrophy resembling post-polio syndrome]. 1例の脊髄灰白質炎後症候群に類似した頚椎症性筋萎縮.Rinsho Shinkeigaku. 2006;46(1):59–61. Japanese.
  • Mortezaee K, Khanlarkhani N, Beyer C, Zendedel A. Inflammasome: its role in traumatic brain and spinal cord injury. J Cell Physiol. 2018;233(7):5160–5169. doi:10.1002/jcp.26287.
  • Li Y, Ritzel RM, Khan N, et al. Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice. Theranostics. 2020;10(25):11376–11403. doi:10.7150/thno.49199
  • Pfyffer D, Wyss PO, Huber E, et al. Metabolites of neuroinflammation relate to neuropathic pain after spinal cord injury. Neurology. 2020;95(7):e805–e814. doi:10.1212/wnl.0000000000010003
  • Brockie S, Hong J, Fehlings MG. The role of microglia in modulating neuroinflammation after spinal cord injury. Int J Mol Sci. 2021;22(18). doi:10.3390/ijms22189706
  • Swanson KV, Deng M, Ting JP. The NLRP3 inflammasome: molecular activation and regulation to therapeutics. Nat Rev Immunol. 2019;19(8):477–489. doi:10.1038/s41577-019-0165-0
  • Gaidt MM, Hornung V. The NLRP3 inflammasome renders cell death pro-inflammatory. J Mol Biol. 2018;430(2):133–141. doi:10.1016/j.jmb.2017.11.013
  • Al Mamun A, Wu Y, Monalisa I, et al. Role of pyroptosis in spinal cord injury and its therapeutic implications. J Adv Res. 2021;28:97–109. doi:10.1016/j.jare.2020.08.004
  • Tsubaki H, Tooyama I, Walker DG. Thioredoxin-interacting protein (TXNIP) with focus on brain and neurodegenerative diseases. Int J Mol Sci. 2020;21(24). doi:10.3390/ijms21249357
  • Pan M, Zhang F, Qu K, Liu C, Zhang J. TXNIP: a double-edged sword in disease and therapeutic outlook. Oxid Med Cell Longev. 2022;2022:7805115. doi:10.1155/2022/7805115
  • Yu P, Zhang X, Liu N, et al. Pyroptosis: mechanisms and diseases. Signal Transduct Target Ther. 2021;6(1):128. doi:10.1038/s41392-021-00507-5
  • Ren Z, Liang W, Sheng J, et al. Gal-3 is a potential biomarker for spinal cord injury and Gal-3 deficiency attenuates neuroinflammation through ROS/TXNIP/NLRP3 signaling pathway. Biosci Rep. 2019;39(12). doi:10.1042/bsr20192368
  • Pan Z, Shan Q, Gu P, et al. miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis. J Neuroinflammation. 2018;15(1):29. doi:10.1186/s12974-018-1073-0
  • Hu T, Sun Q, Gou Y, et al. Salidroside alleviates chronic constriction injury-induced neuropathic pain and inhibits of TXNIP/NLRP3 pathway. Neurochem Res. 2021. doi:10.1007/s11064-021-03459-y
  • Vidal PM, Ulndreaj A, Badner A, Hong J, Fehlings MG. Methylprednisolone treatment enhances early recovery following surgical decompression for degenerative cervical myelopathy without compromise to the systemic immune system. J Neuroinflammation. 2018;15(1):222. doi:10.1186/s12974-018-1257-7
  • Basso DM, Beattie MS, Bresnahan JC. A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma. 1995;12(1):1–21. doi:10.1089/neu.1995.12.1
  • Chung D, Cho DC, Park SH, et al. Cold allodynia after C2 root resection in Sprague-Dawley rats. J Korean Neurosurg Soc. 2018;61(2):186–193. doi:10.3340/jkns.2017.0404.019
  • Rivlin AS, Tator CH. Effect of duration of acute spinal cord compression in a new acute cord injury model in the rat. Surg Neurol. 1978;10(1):38–43.
  • Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol. 2010;11(2):136–140. doi:10.1038/ni.1831
  • Miao J, Zhou X, Ji T, Chen G. NF-κB p65-dependent transcriptional regulation of histone deacetylase 2 contributes to the chronic constriction injury-induced neuropathic pain via the microRNA-183/TXNIP/NLRP3 axis. J Neuroinflammation. 2020;17(1):225. doi:10.1186/s12974-020-01901-6
  • Kurokawa R, Murata H, Ogino M, Ueki K, Kim P. Altered blood flow distribution in the rat spinal cord under chronic compression. Spine. 2011;36(13):1006–1009. doi:10.1097/BRS.0b013e3181eaf33d
  • Zhou Z, He M, Zhao Q, et al. Panax notoginseng saponins attenuate neuroinflammation through TXNIP-mediated NLRP3 inflammasome activation in aging rats. Curr Pharm Biotechnol. 2021;22(10):1369–1379. doi:10.2174/1389201021999201110204735
  • Zahid A, Li B, Kombe AJK, Jin T, Tao J. Pharmacological inhibitors of the NLRP3 inflammasome. Front Immunol. 2019;10:2538. doi:10.3389/fimmu.2019.02538
  • Li N, Zhao T, Cao Y, et al. Tangshen formula attenuates diabetic kidney injury by imparting anti-pyroptotic effects via the TXNIP-NLRP3-GSDMD axis. Front Pharmacol. 2020;11:623489. doi:10.3389/fphar.2020.623489
  • Ji L, Wang Q, Huang F, et al. FOXO1 overexpression attenuates tubulointerstitial fibrosis and apoptosis in diabetic kidneys by ameliorating oxidative injury via TXNIP-TRX. Oxid Med Cell Longev. 2019;2019:3286928. doi:10.1155/2019/3286928
  • Lv H, Zhu C, Wei W, et al. Enhanced Keap1-Nrf2/Trx-1 axis by daphnetin protects against oxidative stress-driven hepatotoxicity via inhibiting ASK1/JNK and Txnip/NLRP3 inflammasome activation. Phytomedicine. 2020;71:153241. doi:10.1016/j.phymed.2020.153241
  • Nishinaka Y, Masutani H, Oka S, et al. Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1. J Biol Chem. 2004;279(36):37559–37565. doi:10.1074/jbc.M405473200
  • Suh HW, Yun S, Song H, et al. TXNIP interacts with hEcd to increase p53 stability and activity. Biochem Biophys Res Commun. 2013;438(2):264–269. doi:10.1016/j.bbrc.2013.07.036