Reactive Hemophagocytic Lymphohistiocytosis Secondary to Ovarian Adenocarcinoma: A Rare Case Report

References

• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70(1):7–30. doi:10.3322/caac.21590
   PubMed Web of Science ®Google Scholar
• Lheureux S, Gourley C, Vergote I, et al. Epithelial ovarian cancer. Lancet. 2019;393(10177):1240–1253. doi:10.1016/S0140-6736(18)32552-2
   PubMed Web of Science ®Google Scholar
• Gaona-Luviano P, Medina-Gaona LA, Magaña-Pérez K. Epidemiology of ovarian cancer. Chin Clin Oncol. 2020;9(4):47. doi:10.21037/cco-20-34
   PubMed Web of Science ®Google Scholar
• Astigarraga I, Gonzalez-Granado LI, Allende LM, et al. Haemophagocytic syndromes: the importance of early diagnosis and treatment. Pediatr. 2018;89(2):124.e1–124.e8. doi:10.1016/j.anpedi.2018.05.003
   Web of Science ®Google Scholar
• Chahine Z, Jayakrishnan T, Samhouri Y, et al. Haemophagocytic lymphohistiocytosis that spontaneously resolved: a case of EBV. BMJ Case Rep. 2020;13(11):e235544. doi:10.1136/bcr-2020-235544
   PubMedGoogle Scholar
• Risma KA, Marsh RA. Hemophagocytic lymphohistiocytosis: clinical presentations and diagnosis. J Allergy Clin Immunol Pract. 2019;7(3):824–832. doi:10.1016/j.jaip.2018.11.050
   PubMed Web of Science ®Google Scholar
• Seo JJ. Hematopoietic cell transplantation for hemophagocytic lymphohistiocytosis: recent advances and controversies. Blood Res. 2015;50(3):131–139. doi:10.5045/br.2015.50.3.131
   PubMedGoogle Scholar
• Mendes FR, Sobral KM, Culler HF, et al. Acquired hemophagocytic lymphohistiocytosis as initial manifestation of multiple myeloma: a case report and literature review. Medicine. 2020;99(39):e22299. doi:10.1097/MD.0000000000022299
   PubMed Web of Science ®Google Scholar
• Henter JI, Horne A, Arico M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007;48(2):124–131. doi:10.1002/pbc.21039
   PubMed Web of Science ®Google Scholar
• Fardet L, Galicier L, Lambotte O, et al. Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndrome. Arthritis Rheumatol. 2014;66(9):2613–2620. doi:10.1002/art.38690
   PubMed Web of Science ®Google Scholar
• Ramos-Casals M, Brito-Zerón P, López-Guillermo A, et al. Adult haemophagocytic syndrome. Lancet. 2014;383(9927):1503–1516. doi:10.1016/S0140-6736(13)61048-X
   PubMed Web of Science ®Google Scholar
• Ishii E, Ohga S, Imashuku S, et al. Nationwide survey of hemophagocytic lymphohistiocytosis in Japan. Int J Hematol. 2007;86(1):58–65. doi:10.1532/IJH97.07012
   PubMed Web of Science ®Google Scholar
• Kapoor S, Morgan CK, Siddique MA, et al. Intensive care unit complications and outcomes of adult patients with hemophagocytic lymphohistiocytosis: a retrospective study of 16 cases. World J Crit Care Med. 2018;7(6):73–83. doi:10.5492/wjccm.v7.i6.73
   PubMedGoogle Scholar
• Machaczka M, Vaktnas J, Klimkowska M, et al. Malignancy-associated hemophagocytic lymphohistiocytosis in adults: a retrospective population-based analysis from a single center. Leuk Lymphoma. 2011;52(4):613–619. doi:10.3109/10428194.2010.551153
   PubMed Web of Science ®Google Scholar
• Tamamyan GN, Kantarjian HM, Ning J, et al. Malignancy-associated hemophagocytic lymphohistiocytosis in adults: relation to hemophagocytosis, characteristics, and outcomes. Cancer. 2016;122(18):2857–2866. doi:10.1002/cncr.30084
   PubMed Web of Science ®Google Scholar
• Barba T, Maucort-Boulch D, Iwaz J, et al. Hemophagocytic lymphohistiocytosis in intensive care unit: a 71-compliant retrospective study. Medicine. 2015;94(51):e2318. doi:10.1097/MD.0000000000002318
   PubMed Web of Science ®Google Scholar
• Sakai T, Shiraki K, Deguchi M, et al. Hepatocellular carcinoma associated with hemophagocytic syndrome. Hepatogastroenterology. 2001;48(41):1464–1466.
   PubMedGoogle Scholar
• Dumont L, Salaroli A, Dal Lago L, et al. Prostate cancer and reactive haemophagocytic lymphohistiocytosis. Eur J Case Rep Intern Med. 2021;8(4):002425. doi:10.12890/2021_002425
   PubMedGoogle Scholar
• Koizumi K, Haseyama Y, Machino R, et al. The hemophagocytic syndrome in prostate cancer revealed by disseminated carcinomatosis of the bone marrow. J Urol. 2002;168(3):1101–1102. doi:10.1016/S0022-5347(05)64588-0
   PubMed Web of Science ®Google Scholar
• Declerck L, Adenis C, Amela E, et al. Prostate cancer related haemophagocytic syndrome: successful treatment with chemotherapy. Acta Oncol. 2012;51(2):268–269. doi:10.3109/0284186X.2011.608377
   PubMed Web of Science ®Google Scholar
• Nosratian-Baskovic M, Tan B, Folkins A, et al. Hemophagocytic lymphohistiocytosis as a paraneoplastic syndrome associated with ovarian dysgerminoma. Gynecol Oncol Rep. 2016;17:38–41. doi:10.1016/j.gore.2016.05.013
   PubMedGoogle Scholar
• Sandnes M, Ulvik RJ, Vorland M, et al. Hyperferritinemia-A clinical overview. J Clin Med. 2021;10(9):2008. doi:10.3390/jcm10092008
   PubMed Web of Science ®Google Scholar
• Knaak C, Nyvlt P, Schuster FS, et al. Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore. Crit Care. 2020;24(1):244. doi:10.1186/s13054-020-02941-3
   PubMed Web of Science ®Google Scholar
• Mottaghipisheh H, Kalantar K, Amanati A, et al. Comparison of the clinical features and outcome of children with hemophagocytic lymphohistiocytosis (HLH) secondary to visceral leishmaniasis and primary HLH: a single-center study. BMC Infect Dis. 2021;21(1):732. doi:10.1186/s12879-021-06408-w
   PubMed Web of Science ®Google Scholar
• Merrill SA, Naik R, Streiff MB, et al. A prospective quality improvement initiative in adult hemophagocytic lymphohistiocytosis to improve testing and a framework to facilitate trigger identification and mitigate hemorrhage from retrospective analysis. Medicine. 2018;97(31):e11579. doi:10.1097/MD.0000000000011579
   PubMed Web of Science ®Google Scholar
• Lachmann G, Spies C, Schenk T, et al. Hemophagocytic lymphohistiocytosis: potentially underdiagnosed in intensive care units. Shock. 2018;50(2):149–155. doi:10.1097/SHK.0000000000001048
   PubMed Web of Science ®Google Scholar
• Lachmann G, Knaak C, von Haefen C, et al. Diagnostic biomarkers for adult haemophagocytic lymphohistiocytosis in critically ill pse Strobe-Coatients (HEMICU): a prospective observational study protocol. BMJ Open. 2019;9(10):e032695. doi:10.1136/bmjopen-2019-032695
   PubMed Web of Science ®Google Scholar
• Dalal BI, Vakil AP, Khare NS, et al. Abnormalities of the lymphocyte subsets and their immunophenotype, and their prognostic significance in adult patients with hemophagocytic lymphohistiocytosis. Ann Hematol. 2015;94(7):1111–1117. doi:10.1007/s00277-015-2350-y
   PubMed Web of Science ®Google Scholar
• Carvelli J, Piperoglou C, Farnarier C, et al. Functional and genetic testing in adults with HLH reveals an inflammatory profile rather than a cytotoxicity defect. Blood. 2020;136(5):542–552. doi:10.1182/blood.2019003664
   PubMed Web of Science ®Google Scholar
• Griffin G, Shenoi S, Hughes GC. Hemophagocytic lymphohistiocytosis: an update on pathogenesis, diagnosis, and therapy. Best Pract Res Clin Rheumatol. 2020;34(4):101515. doi:10.1016/j.berh.2020.101515
   PubMed Web of Science ®Google Scholar
• Merli P, Quintarelli C, Strocchio L, et al. The role of interferon-gamma and its signaling pathway in pediatric hematological disorders. Pediatr Blood Cancer. 2021;68(4):e28900. doi:10.1002/pbc.28900
   PubMed Web of Science ®Google Scholar
• Chiossone L, Dumas PY, Vienne M, et al. Natural killer cells and other innate lymphoid cells in cancer. Nat Rev Immunol. 2018;18(11):671–688. doi:10.1038/s41577-018-0061-z
   PubMed Web of Science ®Google Scholar
• Di Vito C, Mikulak J, Zaghi E, et al. NK cells to cure cancer. Semin Immunol. 2019;41:101272. doi:10.1016/j.smim.2019.03.004
   PubMed Web of Science ®Google Scholar
• Parodi E, Romano F, Ramenghi U. How we use reticulocyte parameters in workup and management of pediatric hematologic diseases. Front Pediatr. 2020;8:588617. doi:10.3389/fped.2020.588617
   PubMed Web of Science ®Google Scholar
• Yoshihara S, Li Y, Xia J, et al. Posttransplant hemophagocytic lymphohistiocytosis driven by myeloid cytokines and vicious cycles of T-Cell and macrophage activation in humanized mice. Front Immunol. 2019;10:186. doi:10.3389/fimmu.2019.00186
   PubMed Web of Science ®Google Scholar
• Ru YX, Bao ST, Dong SX, et al. Analysis of monocyte and histiocytic cell populations in bone marrow of patients with confirmed and suspected cases of reactive histocytosis. Ultrastruct Pathol. 2013;37(2):93–101. doi:10.3109/01913123.2012.742174
   PubMed Web of Science ®Google Scholar